All Stories

  1. Modulating mRNA carrier efficacy through the molecular catwalk of ionizable nitrogens in lipidic domains
  2. Spatiotemporal Nanotransformers for Antitumoral Orchestration of Protein Homeostasis
  3. Nano/micro-scale targeted RNA delivery systems for cancer therapy
  4. PEGylation Enhances Colloidal Stability and Promotes Ligand-Mediated Targeting of LAF–Xenopeptide mRNA Complexes
  5. Have we finally found the ideal nucleic acid carrier with lipo-xenopeptides?
  6. CRISPR/Cas9 Ribonucleoprotein Delivery Enhanced by Lipo-Xenopeptide Carriers and Homology-Directed Repair Modulators: Insights from Reporter Cell Lines
  7. Evolution of Lipo-Xenopeptide Carriers for siRNA Delivery: Interplay of Stabilizing Subunits
  8. Ionic Coating of siRNA Polyplexes with cRGD–PEG–Hyaluronic Acid To Modulate Serum Stability and In Vivo Performance
  9. Dual pH-responsive CRISPR/Cas9 ribonucleoprotein xenopeptide complexes for genome editing
  10. New insights for the development of efficient DNA vaccines
  11. Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo
  12. Advancing delivery of RNA therapeutics with cationizable xenopeptides
  13. Strategies and mechanisms for endosomal escape of therapeutic nucleic acids
  14. Correction: Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression
  15. In Vivo Endothelial Cell Gene Silencing by siRNA‐LNPs Tuned with Lipoamino Bundle Chemical and Ligand Targeting
  16. Dual Effect by Chemical Electron Transfer Enhanced siRNA Lipid Nanoparticles: Reactive Oxygen Species-Triggered Tumor Cell Killing Aggravated by Nrf2 Gene Silencing
  17. Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose
  18. Tumor-targeted PROTAC prodrug nanoplatform enables precise protein degradation and combination cancer therapy
  19. GalNAc- or Mannose-PEG-Functionalized Polyplexes Enable Effective Lectin-Mediated DNA Delivery
  20. Dynamic carriers for therapeutic RNA delivery
  21. Nucleic acid delivery to retinal cells using lipopeptides as a potential tool towards ocular gene therapies
  22. Crosstalk Between NK Cell Receptors and Tumor Membrane Hsp70‐Derived Peptide: A Combined Computational and Experimental Study
  23. Lipoamino bundle LNPs for efficient mRNA transfection of dendritic cells and macrophages show high spleen selectivity
  24. Modulating efficacy and cytotoxicity of lipoamino fatty acid nucleic acid carriers using disulfide or hydrophobic spacers
  25. Transcriptional Targeting of Dendritic Cells Using an Optimized Human Fascin1 Gene Promoter
  26. mCherry on Top: A Positive Read-Out Cellular Platform for Screening DMD Exon Skipping Xenopeptide–PMO Conjugates
  27. From structural design to delivery: mRNA therapeutics for cancer immunotherapy
  28. Unravelling the metastasis-preventing effect of miR-200cin vitroandin vivo
  29. Receptor-Targeted Carbon Nanodot Delivery through Polymer Caging and Click Chemistry-Supported LRP1 Ligand Attachment
  30. High-resolution bioenergetics correlates the length of continuous protonatable diaminoethane motif of four-armed oligo(ethanamino)amide transfectants to cytotoxicity
  31. Interleukin-6-controlled, mesenchymal stem cell-based sodium/iodide symporter gene therapy improves survival of glioblastoma-bearing mice
  32. Peptide nucleic acid-zirconium coordination nanoparticles
  33. Chemical Evolution of Amphiphilic Xenopeptides for Potentiated Cas9 Ribonucleoprotein Delivery
  34. Iron-Gallic Acid Peptide Nanoparticles as a Versatile Platform for Cellular Delivery with Synergistic ROS Enhancement Effect
  35. Chemical-electron-transfer-based lipopolyplexes for enhanced siRNA delivery
  36. Molecular Chameleon Carriers for Nucleic Acid Delivery: The Sweet Spot Between Lipoplexes and Polyplexes
  37. Mesenchymal Stem Cell–mediated Image-guided Sodium Iodide Symporter (NIS) Gene Therapy Improves Survival of Glioblastoma-bearing Mice
  38. Dual EGFR- and TfR-targeted gene transfer for sodium iodide symporter gene therapy of glioblastoma
  39. Folate Receptor‐Mediated Delivery of Cas9 RNP for Enhanced Immune Checkpoint Disruption in Cancer Cells
  40. Combating Drug Resistance by Exploiting miRNA-200c-Controlled Phase II Detoxification
  41. Biomimetic Mineralization of Iron-Fumarate Nanoparticles for Protective Encapsulation and Intracellular Delivery of Proteins
  42. A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology
  43. Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery
  44. A Novel Piggyback Strategy for mRNA Delivery Exploiting Adenovirus Entry Biology
  45. Receptor-Targeted Dual pH-Triggered Intracellular Protein Transfer
  46. Targeting nucleic acid-based therapeutics to tumors: Challenges and strategies for polyplexes
  47. CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells
  48. The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy
  49. Performance of nanoparticles for biomedical applications: The in vitro/in vivo discrepancy
  50. Cross‐Linkable Polyion Complex Micelles from Polypept(o)ide‐Based ABC‐Triblock Copolymers for siRNA Delivery
  51. Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
  52. Correction to “Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release”
  53. Selective sodium iodide symporter (NIS) gene therapy of glioblastoma mediated by EGFR-targeted lipopolyplexes
  54. NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development
  55. Transferrin Receptor Targeted Polyplexes Completely Comprised of Sequence‐Defined Components
  56. Dynamic mRNA polyplexes benefit from bioreducible cleavage sites for in vitro and in vivo transfer
  57. The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatment
  58. Gene Therapy “Made in Germany”: A Historical Perspective, Analysis of the Status Quo, and Recommendations for Action by the German Society for Gene Therapy
  59. Transient Permeabilization of Living Cells: Combining Shear Flow and Acoustofluidic Trapping for the Facilitated Uptake of Molecules
  60. Optimizing pDNA Lipo-polyplexes: A Balancing Act between Stability and Cargo Release
  61. Regional Hyperthermia Enhances Mesenchymal Stem Cell Recruitment to Tumor Stroma: Implications for Mesenchymal Stem Cell-Based Tumor Therapy
  62. Synergistic Combination of Calcium and Citrate in Mesoporous Nanoparticles Targets Pleural Tumors
  63. Carriers for Nucleic Acid Delivery to the Brain
  64. Controlling Nanoparticle Formulation: A Low-Budget Prototype for the Automation of a Microfluidic Platform
  65. Hyaluronate siRNA nanoparticles with positive charge display rapid attachment to tumor endothelium and penetration into tumors
  66. Versatile, Multifunctional Block Copolymers for the Self-Assembly of Well-Defined, Nontoxic pDNA Polyplexes
  67. A Multistage Cooperative Nanoplatform Enables Intracellular Co‐Delivery of Proteins and Chemotherapeutics for Cancer Therapy
  68. Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
  69. Nucleic Acid-Based Approaches for Tumor Therapy
  70. Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles
  71. Protein-drug conjugate programmed by pH-reversible linker for tumor hypoxia relief and enhanced cancer combination therapy
  72. Optimizing synthetic nucleic acid and protein nanocarriers: The chemical evolution approach
  73. Tuning the Morphological Appearance of Iron(III) Fumarate: Impact on Material Characteristics and Biocompatibility
  74. Delivery of Cas9/sgRNA Ribonucleoprotein Complexes via Hydroxystearyl Oligoamino Amides
  75. Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells
  76. Artificial peptides for antitumoral siRNA delivery
  77. Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells
  78. Polymer-Based Tumor-targeted Nanosystems
  79. Inducible microRNA-200c decreases motility of breast cancer cells and reduces filamin A
  80. Downregulation of GRK5 hampers the migration of breast cancer cells
  81. A microfluidic approach for sequential assembly of siRNA polyplexes with a defined structure-activity relationship
  82. Co-delivery of pretubulysin and siEG5 to EGFR overexpressing carcinoma cells
  83. Core‐Shell Functionalized Zirconium‐Pemetrexed Coordination Nanoparticles as Carriers with a High Drug Content
  84. Polymeric Carriers for Nucleic Acid Delivery: Current Designs and Future Directions
  85. Supramolecular Assembly of Aminoethylene‐Lipopeptide PMO Conjugates into RNA Splice‐Switching Nanomicelles
  86. Radiation-Induced Amplification of TGFB1-Induced Mesenchymal Stem Cell–Mediated Sodium Iodide Symporter (NIS) Gene 131I Therapy
  87. Combination Chemotherapy of L1210 Tumors in Mice with Pretubulysin and Methotrexate Lipo-Oligomer Nanoparticles
  88. A microfluidic approach for sequential assembly of siRNA polyplexes with defined structure – activity relationship
  89. A microfluidic approach for sequential assembly of siRNA polyplexes with defined structure – activity relationship
  90. IL4‐Receptor‐Targeted Dual Antitumoral Apoptotic Peptide—siRNA Conjugate Lipoplexes
  91. Size tunable nanoparticle formation employing droplet fusion by acoustic streaming applied to polyplexes
  92. Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy
  93. Coordinative Binding of Polymers to Metal–Organic Framework Nanoparticles for Control of Interactions at the Biointerface
  94. Targeting APLN/APLNR Improves Antiangiogenic Efficiency and Blunts Proinvasive Side Effects of VEGFA/VEGFR2 Blockade in Glioblastoma
  95. MiRNA-27a sensitizes breast cancer cells to treatment with Selective Estrogen Receptor Modulators
  96. Dual-targeted NIS polyplexes—a theranostic strategy toward tumors with heterogeneous receptor expression
  97. Combined antitumoral effects of pretubulysin and methotrexate
  98. Click-Shielded and Targeted Lipopolyplexes
  99. Combinatorial siRNA Polyplexes for Receptor Targeting
  100. Sequence-Defined Cationic Lipo-Oligomers Containing Unsaturated Fatty Acids for Transfection
  101. Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids
  102. TGFB1-driven mesenchymal stem cell-mediated NIS gene transfer
  103. External Beam Radiation Therapy Enhances Mesenchymal Stem Cell–Mediated Sodium–Iodide Symporter Gene Delivery
  104. Bioresponsive polyplexes – chemically programmed for nucleic acid delivery
  105. Precise Enzymatic Cleavage Sites for Improved Bioactivity of siRNA Lipo-Polyplexes
  106. Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo
  107. A proteomic analysis of chemoresistance development via sequential treatment with doxorubicin reveals novel players in MCF‑7 breast cancer cells
  108. Epidermal growth factor receptor targeted methotrexate and small interfering RNA co-delivery
  109. Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines
  110. 2. Nanomedicines for targeted therapy
  111. Efficient Shielding of Polyplexes Using Heterotelechelic Polysarcosines
  112. A proteomic analysis of an in vitro knock-out of miR-200c
  113. In vivo tracking of adipose tissue grafts with cadmium-telluride quantum dots
  114. Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics
  115. Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma
  116. Novel PAMAM-PEG-Peptide Conjugates for siRNA Delivery Targeted to the Transferrin and Epidermal Growth Factor Receptors
  117. Reintroducing the Sodium–Iodide Symporter to Anaplastic Thyroid Carcinoma
  118. Solid-phase supported design of carriers for therapeutic nucleic acid delivery
  119. Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes
  120. Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots
  121. Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery
  122. EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases
  123. EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent
  124. Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Stability forIn VivoGene Silencing in Leukemia
  125. Non-Viral Delivery Vehicles
  126. Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers
  127. Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery
  128. Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines
  129. Antitumoral Cascade-Targeting Ligand for IL-6 Receptor-Mediated Gene Delivery to Glioma
  130. Nanoparticle Technology: Having Impact, but Needing Further Optimization
  131. Polyplex Evolution: Understanding Biology, Optimizing Performance
  132. Systemic tumor-targeted sodium iodide symporter (NIS) gene therapy of hepatocellular carcinoma mediated by B6 peptide polyplexes
  133. Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Shielding of pDNA Nanoparticles
  134. Design of Poly-l -Glutamate-Based Complexes for pDNA Delivery
  135. Corrigendum to “Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo” [Euro. J. Pharm. Biopharm. 105 (2016) 85–96]
  136. Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy
  137. Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the theranostic sodium iodide symporter (NIS) gene
  138. Monitoring integrity and localization of modified single-stranded RNA oligonucleotides using ultrasensitive fluorescence methods
  139. History of Polymeric Gene Delivery Systems
  140. Multifunctional Nanoparticles by Coordinative Self-Assembly of His-Tagged Units with Metal–Organic Frameworks
  141. Cadmium Telluride Quantum Dots as a Fluorescence Marker for Adipose Tissue Grafts
  142. Microfluidic self-assembly of folate-targeted monomolecular siRNA-lipid nanoparticles
  143. Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains
  144. Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes
  145. Intracellular Delivery of Nanobodies for Imaging of Target Proteins in Live Cells
  146. EGF receptor targeted lipo-oligocation polyplexes for antitumoral siRNA and miRNA delivery
  147. Controllable Acoustic Mixing of Fluids in Microchannels for the Fabrication of Therapeutic Nanoparticles
  148. Call for papers: Nanoparticle Development and Applications in Cellular and Molecular Therapies
  149. Acid-labile pHPMA modification of four-arm oligoaminoamide pDNA polyplexes balances shielding and gene transfer activity in vitro and in vivo
  150. Sequence-defined cMET/HGFR-targeted Polymers as Gene Delivery Vehicles for the Theranostic Sodium Iodide Symporter (NIS) Gene
  151. Hypoxia-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery
  152. Salinomycin co-treatment enhances tamoxifen cytotoxicity in luminal A breast tumor cells by facilitating lysosomal degradation of receptor tyrosine kinases
  153. How to Tackle the Challenge of siRNA Delivery with Sequence-Defined Oligoamino Amides
  154. Post-PEGylation of siRNA Lipo-oligoamino Amide Polyplexes Using Tetra-glutamylated Folic Acid as Ligand for Receptor-Targeted Delivery
  155. Ring-Shaped Microlanes and Chemical Barriers as a Platform for Probing Single-Cell Migration
  156. Specially-Made Lipid-Based Assemblies for Improving Transmembrane Gene Delivery: Comparison of Basic Amino Acid Residue Rich Periphery
  157. Imparting Functionality to MOF Nanoparticles by External Surface Selective Covalent Attachment of Polymers
  158. 493. Nonviral Gene Transfer by Sequence-Defined Proton-Sponges with Combined Nucleic Acid Binding and Endosomal Buffering: Balancing Basicities
  159. Targeted siRNA Delivery Using a Lipo-Oligoaminoamide Nanocore with an Influenza Peptide and Transferrin Shell
  160. Combinatorial Optimization of Sequence-Defined Oligo(ethanamino)amides for Folate Receptor-Targeted pDNA and siRNA Delivery
  161. Dual antitumoral potency of EG5 siRNA nanoplexes armed with cytotoxic bifunctional glutamyl-methotrexate targeting ligand
  162. From Artificial Amino Acids to Sequence-Defined Targeted Oligoaminoamides
  163. DNA as Tunable Adaptor for siRNA Polyplex Stabilization and Functionalization
  164. A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair
  165. Highly efficient siRNA delivery from core–shell mesoporous silica nanoparticles with multifunctional polymer caps
  166. Precise redox-sensitive cleavage sites for improved bioactivity of siRNA lipopolyplexes
  167. pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing
  168. Consecutive salinomycin treatment reduces doxorubicin resistance of breast tumor cells by diminishing drug efflux pump expression and activity
  169. Fast Characterization of Polyplexes by Taylor Dispersion Analysis
  170. Enhanced Intracellular Protein Transduction by Sequence Defined Tetra-Oleoyl Oligoaminoamides Targeted for Cancer Therapy
  171. Sequence-defined nucleic acid carriers combining distinct modules for complexation, shielding, receptor-targeting and endosomal escape
  172. Assessing potential peptide targeting ligands by quantification of cellular adhesion of model nanoparticles under flow conditions
  173. Self-assembled amphiphilic sequence-defined PEGylated three-arm oligo(ethanamino)amides via NCL reaction for drug delivery: Impact of building blocks on controlled release
  174. Traceless pH sensitive coating of polyplexes prepared from well-defined polycations
  175. Combination of sequence-defined oligoaminoamides with transferrin-polycation conjugates for receptor-targeted gene delivery
  176. Evaluation of improved PAMAM-G5 conjugates for gene delivery targeted to the transferrin receptor
  177. Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application
  178. Combining polyethylenimine and Fe(III) for mediating pDNA transfection
  179. Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes
  180. Tumor-targeted Delivery of Anti-microRNA for Cancer Therapy: pHLIP is Key
  181. Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)
  182. Mesenchymal Stem Cell-Mediated, Tumor Stroma-Targeted Radioiodine Therapy of Metastatic Colon Cancer Using the Sodium Iodide Symporter as Theranostic Gene
  183. Defined Polymeric Materials for Gene Delivery
  184. Dual-Targeted Polyplexes Based on Sequence-Defined Peptide-PEG-Oligoamino Amides
  185. Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer
  186. Multifunctional polymer-capped mesoporous silica nanoparticles for pH-responsive targeted drug delivery
  187. Multifunctional Oligoaminoamides for the Receptor-Specific Delivery of Therapeutic RNA
  188. Nucleic Acid Medicines: The Polymer Option
  189. Alternation of histone and DNA methylation in human atherosclerotic carotid plaques
  190. Handling Risk Attitudes for Preference Learning and Intelligent Decision Support
  191. Sequence-defined polymers for the delivery of oligonucleotides
  192. Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells
  193. The Actin Targeting Compound Chondramide Inhibits Breast Cancer Metastasis via Reduction of Cellular Contractility
  194. In vitro and in vivo characterization of the actin polymerizing compound chondramide as an angiogenic inhibitor
  195. Sequence-Defined Oligoaminoamides for the Delivery of siRNAs
  196. Sequence-defined shuttles for targeted nucleic acid and protein delivery
  197. Bioreducible Polycations as Shuttles for Therapeutic Nucleic Acid and Protein Transfection
  198. Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ
  199. Synthesis of Core–Shell Graphitic Carbon@Silica Nanospheres with Dual-Ordered Mesopores for Cancer-Targeted Photothermochemotherapy
  200. Stability and activity of hydroxyethyl starch-coated polyplexes in frozen solutions or lyophilizates
  201. 632: Tamoxifen resistance can be overcome by salinomycin treatment
  202. 175: miR-27a is a functional biomarker for tamoxifen treatment of luminal A/B breast tumors
  203. Characterization and compatibility of hydroxyethyl starch–polyethylenimine copolymers for DNA delivery
  204. Synthetic Polyglutamylation of Dual-Functional MTX Ligands for Enhanced Combined Cytotoxicity of Poly(I:C) Nanoplexes
  205. Native chemical ligation for conversion of sequence-defined oligomers into targeted pDNA and siRNA carriers
  206. In vivo imaging of mesenchymal stem cell recruitment into the tumor stroma of hepatocellular carcinoma (HCC) using a HIF-specific sodium iodide symporter gene system
  207. Comb-Like Oligoaminoethane Carriers: Change in Topology Improves pDNA Delivery
  208. Gene Regulation by Intracellular Delivery and Photodegradation of Nanoparticles Containing Small Interfering RNA
  209. Retro-Inverso CendR Peptide-Mediated Polyethyleneimine for Intracranial Glioblastoma-Targeting Gene Therapy
  210. Correlation of Length of Linear Oligo(ethanamino) Amides with Gene Transfer and Cytotoxicity
  211. V-ATPase Inhibition Regulates Anoikis Resistance and Metastasis of Cancer Cells
  212. Simplified Pretubulysin Derivatives and Their Biological Effects on Cancer Cells
  213. Fine-tuning of proton sponges by precise diaminoethanes and histidines in pDNA polyplexes
  214. Polymers for Nucleic Acid Transfer—An Overview
  215. Pretubulysin: a new option for the treatment of metastatic cancer
  216. Salinomycin treatment reduces metastatic tumor burden by hampering cancer cell migration
  217. Influences on Cellular Adhesion of Nanoparticles under Blood Flow-Like Conditions
  218. Nucleic Acid Medicines: The Polymer Option
  219. Gene Transfer with Sequence-Defined Oligo(ethanamino)amides Bioreducibly Attached to a Propylenimine Dendrimer Core
  220. The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells
  221. The proto-oncogene KRAS is targeted by miR-200c
  222. V-ATPase inhibition by archazolid leads to lysosomal dysfunction resulting in impaired cathepsin B activationin vivo
  223. A polyphosphoester conjugate of melphalan as antitumoral agent
  224. Formulation development of lyophilized, long-term stable siRNA/oligoaminoamide polyplexes
  225. Nano-encapsulation of Oligonucleotides for Therapeutic Use
  226. Glutathione-sensitive RGD-Poly(ethylene glycol)-SS-Polyethylenimine for intracranial glioblastoma targeted gene delivery
  227. Systemic Image-Guided Liver Cancer Radiovirotherapy Using Dendrimer-Coated Adenovirus Encoding the Sodium Iodide Symporter as Theranostic Gene
  228. De-targeting by miR-143 decreases unwanted transgene expression in non-tumorigenic cells
  229. Generation of a tumor- and tissue-specific episomal non-viral vector system
  230. Comparison of four different particle sizing methods for siRNA polyplex characterization
  231. Gene silencing and antitumoral effects of Eg5 or Ran siRNA oligoaminoamide polyplexes
  232. Characterization of in vivo chemoresistant human hepatocellular carcinoma cells with transendothelial differentiation capacities
  233. Imaging of mesenchymal stem cell recruitment into the stroma of hepatic colon cancer metastases using the sodium iodide symporter (NIS)
  234. The effect of molar mass and degree of hydroxyethylation on the controlled shielding and deshielding of hydroxyethyl starch-coated polyplexes
  235. Stromal Targeting of Sodium Iodide Symporter Using Mesenchymal Stem Cells Allows Enhanced Imaging and Therapy of Hepatocellular Carcinoma
  236. A Comprehensive Gene Expression Analysis of Resistance Formation upon Metronomic Cyclophosphamide Therapy
  237. Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294
  238. Stabilizing effect of tyrosine trimers on pDNA and siRNA polyplexes
  239. Systemic TNFα Gene Therapy Synergizes With Liposomal Doxorubicine in the Treatment of Metastatic Cancer
  240. Adenoviral Vectors Coated with PAMAM Dendrimer Conjugates Allow CAR Independent Virus Uptake and Targeting to the EGF Receptor
  241. - Bioadhesive Drug Delivery Systems
  242. Potent Retro-Inverso d-Peptide for Simultaneous Targeting of Angiogenic Blood Vasculature and Tumor Cells
  243. Biomaterials in RNAi therapeutics: quo vadis?
  244. EGFR-Targeted Adenovirus Dendrimer Coating for Improved Systemic Delivery of the Theranostic NIS Gene
  245. Gene Therapy for Advanced Melanoma: Selective Targeting and Therapeutic Nucleic Acids
  246. In Vivo Imaging Enables High Resolution Preclinical Trials on Patients’ Leukemia Cells Growing in Mice
  247. Sequence-defined four-arm oligo(ethanamino)amides for pDNA and siRNA delivery: Impact of building blocks on efficacy
  248. Stabilization of polyplexes via polymer crosslinking for efficient siRNA delivery
  249. miR-200c Sensitizes Breast Cancer Cells to Doxorubicin Treatment by Decreasing TrkB and Bmi1 Expression
  250. Sequence Defined Disulfide-Linked Shuttle for Strongly Enhanced Intracellular Protein Delivery
  251. Anti-angiogenic effects of the tubulysin precursor pretubulysin and of simplified pretubulysin derivatives
  252. The V-ATPase-Inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1
  253. Synthesis of Polyethylenimine-Based Nanocarriers for Systemic Tumor Targeting of Nucleic Acids
  254. Therapeutic plasmid DNA versus siRNA delivery: Common and different tasks for synthetic carriers
  255. Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery
  256. Acid-Labile Traceless Click Linker for Protein Transduction
  257. Tuning Nanoparticle Uptake: Live-Cell Imaging Reveals Two Distinct Endocytosis Mechanisms Mediated by Natural and Artificial EGFR Targeting Ligand
  258. Structure–activity relationships of siRNA carriers based on sequence-defined oligo (ethane amino) amides
  259. New Sequence-Defined Polyaminoamides with Tailored Endosomolytic Properties for Plasmid DNA Delivery
  260. Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells
  261. Controlled shielding and deshielding of gene delivery polyplexes using hydroxyethyl starch (HES) and alpha-amylase
  262. Synthesis and characterization of new platinum(II) phosphinate complexes
  263. PolyIC GE11 polyplex inhibits EGFR-overexpressing tumors
  264. Hydrogen Bonding in α-Aminophosphonic Acids
  265. Synthesis of Linear Polyethylenimine and Use in Transfection
  266. Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino)amides for receptor-mediated gene delivery
  267. Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing
  268. Polymers for siRNA Delivery: Inspired by Viruses to be Targeted, Dynamic, and Precise
  269. Disconnecting the Yin and Yang Relation of Epidermal Growth Factor Receptor (EGFR)-Mediated Delivery: A Fully Synthetic, EGFR-Targeted Gene Transfer System Avoiding Receptor Activation
  270. Image-Guided Tumor-Selective Radioiodine Therapy of Liver Cancer After Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene
  271. Nucleic Acid-Based Therapeutics for Glioblastoma
  272. Nucleic Acid Carriers Based on Precise Polymer Conjugates
  273. Image-guided, Tumor Stroma-targeted 131I Therapy of Hepatocellular Cancer After Systemic Mesenchymal Stem Cell-mediated NIS Gene Delivery
  274. Solid-Phase Synthesis of Sequence-Defined T-, i-, and U-Shape Polymers for pDNA and siRNA Delivery
  275. Invading target cells: multifunctional polymer conjugates as therapeutic nucleic acid carriers
  276. Sustained, high transgene expression in liver with plasmid vectors using optimized promoter-enhancer combinations
  277. To Be Targeted: Is the Magic Bullet Concept a Viable Option for Synthetic Nucleic Acid Therapeutics?
  278. pH-Responsive Release of Acetal-Linked Melittin from SBA-15 Mesoporous Silica
  279. Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry
  280. Liver Detargeting of Adenoviral Vectors by Polymer Coating after Systemic Delivery Using the Sodium Iodide Symporter (NIS) as Reporter Gene
  281. Synthesis, NMR-Spectroscopy, and Molecular Structure of a Phosphonyl Ene Diamine
  282. Development of a lyophilized plasmid/LPEI polyplex formulation with long-term stability—A step closer from promising technology to application
  283. Dual-targeted polyplexes: One step towards a synthetic virus for cancer gene therapy
  284. Epidermal Growth Factor Receptor-targeted 131I-therapy of Liver Cancer Following Systemic Delivery of the Sodium Iodide Symporter Gene
  285. Novel Fmoc-Polyamino Acids for Solid-Phase Synthesis of Defined Polyamidoamines
  286. Functional modification of amide-crosslinked oligoethylenimine for improved siRNA delivery
  287. Functional Polymer Conjugates for Medicinal Nucleic Acid Delivery
  288. Live in vivo imaging of Egr-1 promoter activity during neonatal development, liver regeneration and wound healing
  289. Pyridylhydrazone-based PEGylation for pH-reversible lipopolyplex shielding
  290. The establishment of an up-scaled micro-mixer method allows the standardized and reproducible preparation of well-defined plasmid/LPEI polyplexes
  291. EGFR-Homing dsRNA Activates Cancer-Targeted Immune Response and Eliminates Disseminated EGFR-Overexpressing Tumors in Mice
  292. Live-cell imaging and single-particle tracking of polyplex internalization
  293. Pyridylhydrazone-based PEG for pH-reversible lipopolyplex shielding
  294. In Vivo Imaging In the Individualized Mouse Model of Acute Lymphoblastic Leukemia Enables Highly Sensitive and Continuous Follow up of Patient-Derived Xenografts
  295. Impact of Indium-111 Oxine Labelling on Viability of Human Mesenchymal Stem Cells In Vitro, and 3D Cell-Tracking Using SPECT/CT In Vivo
  296. Multifunctional CPP Polymer System for Tumor-Targeted pDNA and siRNA Delivery
  297. Controlled removal of a nonviral episomal vector from transfected cells
  298. Capsomer-Specific Fluorescent Labeling of Adenoviral Vector Particles Allows for Detailed Analysis of Intracellular Particle Trafficking and the Performance of Bioresponsive Bonds for Vector Capsid Modifications
  299. Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery
  300. Poly(I:C)-Mediated Tumor Growth Suppression in EGF-Receptor Overexpressing Tumors Using EGF-Polyethylene Glycol-Linear Polyethylenimine as Carrier
  301. The impact of carboxyalkylation of branched polyethylenimine on effectiveness in small interfering RNA delivery
  302. Adenovirus-Derived Vectors for Prostate Cancer Gene Therapy
  303. Clinical Adenoviral Gene Therapy for Prostate Cancer
  304. Bioresponsive polymers for the delivery of therapeutic nucleic acids
  305. In vivo chemoresistance of prostate cancer in metronomic cyclophosphamide therapy
  306. Tf-lipoplex-mediated c-Jun silencing improves neuronal survival following excitotoxic damage in vivo
  307. Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy
  308. Peptide- and polymer-based delivery of therapeutic RNA
  309. Photochemical Internalization (PCI): A Technology for Drug Delivery
  310. Chemically Programmed Polymers for Targeted DNA and siRNA Transfection
  311. Improvedin vivogene transfer into tumor tissue by stabilization of pseudodendritic oligoethylenimine-based polyplexes
  312. Hydrophobically Modified Oligoethylenimines as Highly Efficient Transfection Agents for siRNA Delivery
  313. Drug Nanocarriers Labeled With Near-infrared-emitting Quantum Dots (Quantoplexes): Imaging Fast Dynamics of Distribution in Living Animals
  314. Targeted Radioiodine Therapy of Neuroblastoma Tumors following Systemic Nonviral Delivery of the Sodium Iodide Symporter Gene
  315. Influence of the Molecular Weight of Bioreducible Oligoethylenimine Conjugates on the Polyplex Transfection Properties
  316. Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate
  317. Causal Role of Apoptosis-Inducing Factor for Neuronal Cell Death Following Traumatic Brain Injury
  318. Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery
  319. A microscopic view on photo-induced polyplex release from endosomes
  320. Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS
  321. Hyperthermia-Induced Targeting of Thermosensitive Gene Carriers to Tumors
  322. Receptor-Targeted Polyplexes for DNA and siRNA Delivery
  323. Extracellular Targeting of Synthetic Therapeutic Nucleic Acid Formulations
  324. Polyhydroxyethylaspartamide-spermine copolymers: Efficient vectors for gene delivery
  325. Click Chemistry for High-Density Biofunctionalization of Mesoporous Silica
  326. Dynamics of photoinduced endosomal release of polyplexes
  327. Nitric oxide—A novel therapeutic for cancer
  328. An Acid Sensitive Ketal-Based Polyethylene Glycol-Oligoethylenimine Copolymer Mediates Improved Transfection Efficiency at Reduced Toxicity
  329. Hyperthermia induced targeting of thermosensitive gene carriers to tumors
  330. The Silent (R)evolution of Polymeric Nucleic Acid Therapeutics
  331. Acetal Linked Oligoethylenimines for Use As pH-Sensitive Gene Carriers
  332. Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding
  333. Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(β‐amino esters)
  334. Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity
  335. Bid-induced release of AIF from mitochondria causes immediate neuronal cell death
  336. Gene therapy progress and prospects: synthetic polymer-based systems
  337. Induction of Apoptosis in Murine Neuroblastoma by Systemic Delivery of Transferrin-Shielded siRNA Polyplexes for Downregulation of Ran
  338. Mechanism of nonviral nucleic acid and gene delivery
  339. Breathing Life into Polycations:  Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery
  340. Acrolein: unwanted side product or contribution to antiangiogenic properties of metronomic cyclophosphamide therapy?
  341. Monomolecular Assembly of siRNA and Poly(ethylene glycol)−Peptide Copolymers
  342. Converging Paths of Viral and Non-viral Vector Engineering
  343. Photochemical Enhancement of DNA Delivery by EGF Receptor Targeted Polyplexes
  344. Receptor-Mediated Gene Transfer
  345. Photochemical Internalization: A New Tool for Drug Delivery
  346. Proteomic Analysis Reveals Differences in Protein Expression in Spheroid versus Monolayer Cultures of Low-Passage Colon Carcinoma Cells
  347. Novel degradable oligoethylenimine acrylate ester-based pseudodendrimers for in vitro and in vivo gene transfer
  348. Novel Biocompatible Cationic Copolymers Based on Polyaspartylhydrazide Being Potent as Gene Vector on Tumor Cells
  349. Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo
  350. Synthesis and characterization of chemically condensed oligoethylenimine containing beta-aminopropionamide linkages for siRNA delivery
  351. Corrigendum to “Cellular Dynamics of EGF Receptor–targeted Synthetic Viruses”
  352. Correction: EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice
  353. An Acetal-Based PEGylation Reagent for pH-Sensitive Shielding of DNA Polyplexes
  354. Cellular Dynamics of EGF Receptor–Targeted Synthetic Viruses
  355. Programmed drug delivery: nanosystems for tumor targeting
  356. Delayed neuronal death after brain trauma involves p53-dependent inhibition of NF-κB transcriptional activity
  357. Cell and Tissue Targeting of Nucleic Acids for Cancer Gene Therapy
  358. Transcriptionally Targeted Nonviral Gene Transfer Using a β-Catenin/TCF-Dependent Promoter in a Series of Different Human Low Passage Colon Cancer Cells
  359. A dimethylmaleic acid–melittin-polylysine conjugate with reduced toxicity, pH-triggered endosomolytic activity and enhanced gene transfer potential
  360. siRNA delivery by a transferrin-associated lipid-based vector: a non-viral strategy to mediate gene silencing
  361. Degradable gene carriers based on oligomerized polyamines
  362. Effects of Raf-1 siRNA on human cerebral microvascular endothelial cells: A potential therapeutic strategy for inhibition of tumor angiogenesis
  363. Optimizing targeted gene delivery: Chemical modification of viral vectors and synthesis of artificial virus vector systems
  364. DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions
  365. Recent Developments in the Application of Plasmid DNA-Based Vectors and Small Interfering RNA Therapeutics for Cancer
  366. The Internalization Route Resulting in Successful Gene Expression Depends on both Cell Line and Polyethylenimine Polyplex Type
  367. Gene Carriers Based on Hexanediol Diacrylate Linked Oligoethylenimine:  Effect of Chemical Structure of Polymer on Biological Properties
  368. pH-responsive shielding of non-viral gene vectors
  369. Induction of activating transcription factor 3 by anoxia is independent of p53 and the hypoxic HIF signalling pathway
  370. Melittin analogs with high lytic activity at endosomal pH enhance transfection with purified targeted PEI polyplexes
  371. Temperature Dependent Gene Expression Induced by PNIPAM-Based Copolymers:  Potential of Hyperthermia in Gene Transfer
  372. Effects of hypoxia and limited diffusion in tumor cell microenvironment on bystander effect of P450 prodrug therapy
  373. Decorated Rods:  A “Bottom-Up” Self-Assembly of Monomolecular DNA Complexes
  374. The Transport of Nanosized Gene Carriers Unraveled by Live-Cell Imaging
  375. Optimized lipopolyplex formulations for gene transfer to human colon carcinoma cells underin vitro conditions
  376. Photochemical Internalization of Transgenes Controlled by the Heat-shock Protein 70 Promoter
  377. EGF Receptor-Targeted Synthetic Double-Stranded RNA Eliminates Glioblastoma, Breast Cancer, and Adenocarcinoma Tumors in Mice
  378. Apoptosis-Inducing Factor Triggered by Poly(ADP-Ribose) Polymerase and Bid Mediates Neuronal Cell Death after Oxygen-Glucose Deprivation and Focal Cerebral Ischemia
  379. Cryoconserved shielded and EGF receptor targeted DNA polyplexes: cellular mechanisms
  380. Specific Targets in Tumor Tissue for the Delivery of Therapeutic Genes
  381. Toward Synthetic Viruses: Endosomal pH-Triggered Deshielding of Targeted Polyplexes Greatly Enhances Gene Transfer in vitro and in vivo
  382. Contribution of academic research to discovery and development of medicines: current status and future opportunities
  383. Opening of Size-Selective Pores in Endosomes during Human Rhinovirus Serotype 2 In Vivo Uncoating Monitored by Single-Organelle Flow Analysis
  384. C- versus N-terminally linked melittin-polyethylenimine conjugates: the site of linkage strongly influences activity of DNA polyplexes
  385. Targeting of Polyplexes: Toward Synthetic Virus Vector Systems
  386. Non-Viral Vectors for Gene Therapy, Second Edition: Part 2
  387. Transferrin Receptor-Targeted Gene Delivery Systems
  388. Functional Analysis of Genomic DNA, cDNA, and Nucleotide Sequence of the Mature C-Type Natriuretic Peptide Gene in Vascular Cells
  389. Photochemically Enhanced Gene Delivery of EGF Receptor-targeted DNA Polyplexes
  390. Stabilized Nonviral Formulations for the Delivery of MCP-1 Gene into Cells of the Vasculoendothelial System
  391. Targeted nucleic acid delivery into tumors: new avenues for cancer therapy
  392. In vitro andin vivo delivery of intact BAC DNA– comparison of different methods
  393. Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
  394. Strategies to Improve DNA Polyplexes for in Vivo Gene Transfer: Will “Artificial Viruses” Be the Answer?
  395. Tumor-targeted gene therapy: strategies for the preparation of ligand–polyethylene glycol–polyethylenimine/DNA complexes
  396. Nanoparticles bearing polyethyleneglycol-coupled transferrin as gene carriers: preparation and in vitro evaluation
  397. Tissue-dependent factors affect gene delivery to tumors in vivo
  398. Nonviral gene transfer into fetal mouse livers (a comparison between the cationic polymer PEI and naked DNA)
  399. Optical imaging of transferrin targeted PEI/DNA complexes in living subjects
  400. Retrofitting BACs with G418 resistance, luciferase, and oriP and EBNA-1 – new vectors for in vitro and in vivodelivery
  401. Novel Shielded Transferrin−Polyethylene Glycol−Polyethylenimine/DNA Complexes for Systemic Tumor-Targeted Gene Transfer
  402. Reactivation of the Mitosis-Promoting Factor in Postmitotic Cardiomyocytes
  403. Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice
  404. Tumor-targeted gene delivery of tumor necrosis factor-α induces tumor necrosis and tumor regression without systemic toxicity
  405. Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers
  406. Targeting tumors with non-viral gene delivery systems
  407. Somatic gene transfer into the lactating ovine mammary gland
  408. Overcoming the Nuclear Barrier: Cell Cycle Independent Nonviral Gene Transfer with Linear Polyethylenimine or Electroporation
  409. Tumor-targeted gene delivery: an attractive strategy to use highly active effector molecules in cancer treatment
  410. Transmembrane Targeting of DNA with Membrane Active Peptides
  411. Design and gene delivery activity of modified polyethylenimines
  412. DNA/polyethylenimine transfection particles: Influence of ligands, polymer size, and PEGylation on internalization and gene expression
  413. Different Strategies for Formation of PEGylated EGF-Conjugated PEI/DNA Complexes for Targeted Gene Delivery
  414. Functional maturation of dendritic cells by exposure to CD40L transgenic tumor cells, fibroblasts or keratinocytes
  415. Tumor targeting with surface-shielded ligand–polycation DNA complexes
  416. Immunoadjuvant activity of interferon-γ-liposomes co-administered with influenza vaccines
  417. Different behavior of branched and linear polyethylenimine for gene deliveryin vitro andin vivo
  418. Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
  419. Transfection of epithelial cells is enhanced by combined treatment with mannitol and polyethyleneglycol
  420. Xenogenization by tetanus toxoid loading into lymphoblastoid cell lines and primary human tumor cells mediated by polycations and liposomes
  421. The role of lipoprotein lipase in adipose tissue development and metabolism
  422. Interleukin-2 gene-modified allogeneic melanoma cell vaccines can induce cross-protection against syngeneic tumors in mice
  423. A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry
  424. Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System
  425. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus
  426. Polymer Based Systems for Tumor-Targeted Gene Delivery
  427. Application of membrane-active peptides for nonviral gene delivery
  428. Membrane destabilization for improved cystolic delivery
  429. Mannose Polyethylenimine Conjugates for Targeted DNA Delivery into Dendritic Cells
  430. Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport
  431. Liposomes as cytokine-supplement in tumor cell-based vaccines
  432. Immunotherapy of Metastatic Malignant Melanoma by a Vaccine Consisting of Autologous Interleukin 2-Transfected Cancer Cells: Outcome of a Phase I Study
  433. PEGylated DNA/transferrin–PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
  434. Efficient Gene Delivery into Human Dendritic Cells by Adenovirus Polyethylenimine and Mannose Polyethylenimine Transfection
  435. Polycation-based DNA complexes for tumor-targeted gene deliveryin vivo
  436. Development of Transferrin-Polycation/DNA Based Vectors for Gene Delivery to Melanoma Cells
  437. Ligand—Polycation Conjugates for Receptor-Targeted Gene Transfer
  438. Receptor Mediated Gene Transfer
  439. Application of membrane-active peptides for drug and gene delivery across cellular membranes
  440. The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells
  441. Influence of the DNA complexation medium on the transfection efficiency of lipospermine/DNA particles
  442. An RGD–Oligolysine Peptide: A Prototype Construct for Integrin-Mediated Gene Delivery
  443. Effects of membrane-active agents in gene delivery
  444. Polylysine-based transfection systems utilizing receptor-mediated delivery
  445. Increase of proliferation rate and enhancement of antitumor cytotoxicity of expanded human CD3+CD56+ immunologic effector cells by receptor-mediated transfection with the interleukin-7 gene
  446. Gene-Modified Dendritic Cells by Receptor-Mediated Transfection
  447. Stabilization of gene delivery systems by freeze-drying
  448. Coupling of cell-binding ligands to polyethylenimine for targeted gene delivery
  449. Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene
  450. Glycerol and Polylysine Synergize in Their Ability to Rupture Vesicular Membranes: A Mechanism for Increased Transferrin–Polylysine-Mediated Gene Transfer1
  451. Lymphocyte apoptosis: induction by gene transfer techniques
  452. Nomenclature for Synthetic Gene Delivery Systems
  453. Influence of Membrane-Active Peptides on Lipospermine/DNA Complex Mediated Gene Transfer
  454. The cdc2Ms Kinase Is Differently Regulated in the Cytoplasm and in the Nucleus
  455. In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer
  456. Functional Re-expression of Laminin-5 in Laminin-γ2-deficient Human Keratinocytes Modifies Cell Morphology, Motility, and Adhesion
  457. Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene Delivery
  458. Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems
  459. Glycerol Enhancement of Ligand-Polylysine/DNA Transfection
  460. Developmental and Cell Cycle Regulation of Alfalfa nucMs1, a Plant Homolog of the Yeast Nsr1 and Mammalian Nucleolin
  461. Phase I Study to the Immunotherapy of Metastatic Malignant Melanoma by a Cancer Vaccine Consisting of Autologous Cancer Cells Transfected with the Human IL-2 Gene. University of Vienna, Austria
  462. Developmental and cell cycle regulation of alfalfa nucMs1, a plant homolog of the yeast Nsr1 and mammalian nucleolin.
  463. Receptor-Mediated Gene Delivery with Synthetic Virus-Like Particles
  464. Complement Activation by Polylysine-DNA Complexes
  465. Virus-mediated release of endosomal content in vitro: different behavior of adenovirus and rhinovirus serotype 2
  466. Receptor-Mediated Gene Transfer into Human T Lymphocytes via Binding of DNA/CD3 Antibody Particles to the CD3 T Cell Receptor Complex
  467. Regulation of the Tissue Factor Promoter in Endothelial Cells
  468. Rhinovirus-mediated endosomal release of transfection complexes.
  469. Psoralen Treatment of Adenovirus Particles Eliminates Virus Replication and Transcription While Maintaining the Endosomolytic Activity of the Virus Capsid
  470. High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection": The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein
  471. Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes
  472. In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.
  473. Chirale Lactole, XI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler Alkanole
  474. Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis
  475. Efficient Foreign Gene Expression in Epstein-Barr Virus-Transformed Human B-Cells
  476. Carbohydrate receptor-mediated gene transfer to human T leukaemic cells
  477. Gene Therapy for B-cell Lymphoma in a SCID Mouse Model using an Immunoglobulin-Regulated Diphtheria Toxin Gene Delivered by a Novel Adenovirus-Polylysine Conjugate
  478. The Generation of Tumor Vaccines by Adenovirus-Enhanced Transferrinfection of Cytokine Genes into Tumor Cells
  479. Somatic gene therapy for cancer: the utility of transferrinfection in generating ‘tumor vaccines’
  480. Non-viral approaches to gene therapy
  481. Receptor-mediated Gene Transfer to Airway Epithelial Cells in Primary Culture
  482. Direct In Vivo Gene Transfer to Airway Epithelium Employing Adenovirus–Polylysine–DNA Complexes
  483. [42] Receptor-mediated transport of DNA into eukaryotic cells
  484. Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.
  485. Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand
  486. Transferrinfection: A Highly Efficient Way to Express Gene Constructs in Eukaryotic Cells
  487. Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
  488. High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.
  489. Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
  490. High-Efficiency Gene Transfer Mediated by Adenovirus Coupled to DNA–Polylysine Complexes
  491. Gene Transfer to Respiratory Epithelial Cells via the Receptor-mediated Endocytosis Pathway
  492. Effective incorporation of 2'-O-methyl-oligoribonuclectides into liposomes and enhanced cell association through modification with thiocholesterol
  493. Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.
  494. DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety
  495. 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event
  496. Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.
  497. Pheromone, 3.Mitt.: Eine einfache Methode zur Steuerung der Reduktion von ?-Alkoxy-carbonylverbindungen
  498. A simple procedure for the preparation of protected 2′-O-methyl or 2′-O-ethyl ribonucleoside-3′-O-phosphoramidites
  499. Chemie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die R
  500. Chemie von α-Aminonitrilen. Aziridin-2-carbonitril, ein Vorläufer von rca-O3-Phosphoserinnitril und Glycolaldehyd-phosphat
  501. Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.
  502. Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.
  503. Transferrin-polycation conjugates as carriers for DNA uptake into cells.
  504. Ein einfaches Verfahren zur Herstellung anellierter Thiophene
  505. Chirale Lactole, VI. Eine Methode zur Bestimmung der Absolutkonfiguration chiraler α-hydroxysubstituierter Nitrile, Alkine und Aldehyde
  506. Kohlenhydrat-Modelle, I. Kinetische und thermodynamische Effekte bei Acetalisierungsreaktionen enantiomerenreiner Thiolactole
  507. Chirale Lactole, IV. Selektivitäten bei Acetalisierungsreaktionen enantiomerenreiner Lactole am Beispiel von Octahydro-8,9,9-trimethyl-5,8-methano-2H-1-benzopyran-2-ol
  508. Gene Delivery Using Polymer Therapeutics
  509. Nonviral Vector Systems for Cancer Gene Therapy
  510. Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy
  511. In Vitro Gene Transfection with Surface-Modified Gelatin Nanoparticles