All Stories

  1. Flavonoids as Inspiration for the Design and Synthesis of New Antiproliferative, Antiparasitic and Antiviral Compounds: An Account

    Article • Journal of the Brazilian Chemical Society, January 2024, Sociedade Brasileira de Quimica (SBQ)

    Eduardo Salustiano

  2. A Novel Protocol for the Synthesis of 1,2,4-Oxadiazoles Active against Trypanosomatids and Drug-Resistant Leukemia Cell Lines

    Article • Tropical Medicine and Infectious Disease, November 2022, MDPI AG

    Eduardo Salustiano

  3. Detachment of Hexokinase II From Mitochondria Promotes Collateral Sensitivity in Multidrug Resistant Chronic Myeloid Leukemia Cells

    Article • Frontiers in Oncology, May 2022, Frontiers

    Eduardo Salustiano

  4. Intrinsic and Chemotherapeutic Stressors Modulate ABCC-Like Transport in Trypanosoma cruzi

    Article • Molecules, June 2021, MDPI AG

    Eduardo Salustiano

  5. Synthesis of new α-Aryl-α-tetralones and α-Fluoro-α-aryl-α-tetralones, preliminary antiproliferative evaluation on drug resistant cell lines and in silico prediction of ADMETox properties

    Article • Bioorganic Chemistry, May 2021, Elsevier

    Eduardo Salustiano

  6. Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differentially modulating ABC transporters in chronic myeloid leukemias

    Article • Journal of Biological Chemistry, March 2020, American Society for Biochemistry & Molecular Biology (ASBMB)

    Eduardo Salustiano

  7. Thiol efflux mediated by an ABCC-like transporter participates for Trypanosoma cruzi adaptation to environmental and chemotherapeutic stresses

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Eduardo Salustiano

  8. Inhibition of glycosphingolipid biosynthesis reverts multidrug resistance by differential modulation of ABC transporters on chronic myeloid leukemias

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Eduardo Salustiano

  9. Insights into the Biological Evaluation of Pterocarpanquinones and Carbapterocarpans with Anti-tumor Activity against MDR Leukemias

    Article • Anti-Cancer Agents in Medicinal Chemistry, May 2019, Bentham Science Publishers

    Eduardo Salustiano

  10. Enantioselective Synthesis, DFT Calculations, and Preliminary Antineoplastic Activity of Dibenzo 1-Azaspiro[4.5]decanes on Drug-Resistant Leukemias

    Article • The Journal of Organic Chemistry, January 2019, American Chemical Society (ACS)

    Eduardo Salustiano, Professor Pedro Merino

  11. 11a-N-tosyl-5-carbapterocarpans: Synthesis, antineoplastic evaluation and in silico prediction of ADMETox properties

    Article • Bioorganic Chemistry, October 2018, Elsevier

    Eduardo Salustiano

  12. Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses

    Article • Frontiers in Oncology, March 2018, Frontiers

    Eduardo Salustiano

  13. Functional Characterization of ABCC Proteins from Trypanosoma cruzi and Their Involvement with Thiol Transport

    Article • Frontiers in Microbiology, February 2018, Frontiers

    Eduardo Salustiano

  14. In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118

    Article • Investigational New Drugs, May 2016, Springer Science + Business Media

    Eduardo Salustiano

  15. The pterocarpanquinone LQB-118 induces apoptosis in acute myeloid leukemia cells of distinct molecular subtypes and targets FoxO3a and FoxM1 transcription factors

    Article • International Journal of Oncology, August 2014, Spandidos Publications

    Eduardo Salustiano

  16. 11a-N-Tosyl-5-deoxi-pterocarpan (LQB-223), a promising prototype for targeting MDR leukemia cell lines

    Article • European Journal of Medicinal Chemistry, May 2014, Elsevier

    Eduardo Salustiano

  17. LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells

    Article • Investigational New Drugs, May 2010, Springer Science + Business Media

    Eduardo Salustiano

  18. New pterocarpanquinones: Synthesis, antineoplasic activity on cultured human malignant cell lines and TNF-α modulation in human PBMC cells

    Article • Bioorganic & Medicinal Chemistry, February 2010, Elsevier

    Eduardo Salustiano

  19. Comparison of the cytotoxic effect of lapachol, α-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells

    Article • Investigational New Drugs, March 2009, Springer Science + Business Media

    Eduardo Salustiano

  20. (±)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: Cytotoxic effect on human leukemia cell lines

    Article • European Journal of Medicinal Chemistry, February 2009, Elsevier

    Eduardo Salustiano