All Stories

  1. Angiotensin (1–7) delivered orally via probiotic, but not subcutaneously, benefits the gut-brain axis in older rats

    Article • GeroScience, May 2020, Springer Science + Business Media

    Drake Morgan

  2. Therapeutic Delivery of Ang(1–7) via Genetically Modified Probiotic: A Dosing Study

    Article • The Journals of Gerontology Series A, October 2019, Oxford University Press (OUP)

    Drake Morgan

  3. Oestradiol and leptin have separate but additive anorexigenic effects and differentially target fat mass in rats

    Article • Journal of Neuroendocrinology, October 2018, Wiley

    Dr Hale Z Toklu, Drake Morgan

  4. Limiting feeding to the active phase reduces blood pressure without the necessity of caloric reduction or fat mass loss

    Article • AJP Regulatory Integrative and Comparative Physiology, October 2018, American Physiological Society

    Drake Morgan

  5. ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old rats

    Article • Experimental Gerontology, October 2018, Elsevier

    Drake Morgan

  6. Activation of the central melanocortin system in rats persistently reduces body and fat mass independently of caloric reduction

    Article • Canadian Journal of Physiology and Pharmacology, March 2018, Canadian Science Publishing

    Drake Morgan

  7. iBAT sympathetic innervation is not required for body weight loss induced by central leptin delivery

    Article • AJP Endocrinology and Metabolism, March 2018, American Physiological Society

    Drake Morgan

  8. Mitochondrial ATP transporter depletion protects mice against liver steatosis and insulin resistance

    Article • Nature Communications, February 2017, Springer Science + Business Media

    Drake Morgan

  9. Intracerebroventricular tempol administration in older rats reduces oxidative stress in the hypothalamus but does not change STAT3 signalling or SIRT1/AMPK pathway

    Article • Applied Physiology Nutrition and Metabolism, January 2017, Canadian Science Publishing

    Dr Hale Z Toklu, Drake Morgan

  10. Anorexic response to rapamycin does not appear to involve a central mechanism

    Article • Clinical and Experimental Pharmacology and Physiology, July 2016, Wiley

    Dr Hale Z Toklu, Drake Morgan

  11. Onset of leptin resistance shows temporal differences related to dose or pulsed treatment

    Article • European Journal of Pharmacology, May 2016, Elsevier

    Drake Morgan

  12. Temporal MRI characterization, neurobiochemical and neurobehavioral changes in a mouse repetitive concussive head injury model

    Article • Scientific Reports, June 2015, Springer Science + Business Media

    Drake Morgan

  13. Rapamycin Versus Intermittent Feeding: Dissociable Effects on Physiological and Behavioral Outcomes When Initiated Early and Late in Life

    Article • The Journals of Gerontology Series A, January 2015, Oxford University Press (OUP)

    Drake Morgan

  14. Rapamycin Normalizes Serum Leptin by Alleviating Obesity and Reducing Leptin Synthesis in Aged Rats

    Article • The Journals of Gerontology Series A, January 2015, Oxford University Press (OUP)

    Drake Morgan

  15. A Novel Aminotetralin-Type Serotonin (5-HT) 2C Receptor-Specific Agonist and 5-HT2A Competitive Antagonist/5-HT2B Inverse Agonist with Preclinical Efficacy for Psychoses

    Article • Journal of Pharmacology and Experimental Therapeutics, February 2014, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Drake Morgan

  16. Intake-dependent effects of cocaine self-administration on impulsive choice in a delay discounting task.

    Article • Behavioral Neuroscience, January 2014, American Psychological Association (APA)

    Drake Morgan

  17. Adolescent Risk Taking, Cocaine Self-Administration, and Striatal Dopamine Signaling

    Article • Neuropsychopharmacology, October 2013, Springer Science + Business Media

    Drake Morgan

  18. Molecular Pharmacology and Ligand Docking Studies Reveal a Single Amino Acid Difference between Mouse and Human Serotonin 5-HT2A Receptors That Impacts Behavioral Translation of Novel 4-Phenyl-2-dimethylaminotetralin Ligands

    Article • Journal of Pharmacology and Experimental Therapeutics, September 2013, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Drake Morgan

  19. Molecular and behavioral pharmacology of two novel orally-active 5HT2 modulators: Potential utility as antipsychotic medications

    Article • Neuropharmacology, September 2013, Elsevier

    Drake Morgan

  20. Thermal sensitivity across ages and during chronic fentanyl administration in rats

    Article • Psychopharmacology, July 2013, Springer Science + Business Media

    Drake Morgan

  21. Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model

    Article • Neuropharmacology, July 2013, Elsevier

    Drake Morgan

  22. Nonhuman primate models of social behavior and cocaine abuse

    Article • Psychopharmacology, August 2012, Springer Science + Business Media

    Drake Morgan

  23. Late-life enalapril administration induces nitric oxide-dependent and independent metabolic adaptations in the rat skeletal muscle

    Article • AGE, May 2012, Springer Science + Business Media

    Drake Morgan

  24. Head-twitch response in rodents induced by the hallucinogen 2,5-dimethoxy-4-iodoamphetamine: a comprehensive history, a re-evaluation of mechanisms, and its utility as a model

    Article • Drug Testing and Analysis, April 2012, Wiley

    Drake Morgan

  25. Effects of Morphine on Thermal Sensitivity in Adult and Aged Rats

    Article • The Journals of Gerontology Series A, December 2011, Oxford University Press (OUP)

    Drake Morgan

  26. Methods in Drug Abuse Models: Comparison of Different Models of Methamphetamine Paradigms

    Article • December 2011, Springer Science + Business Media

    Dr. Firas Kobeissy, Drake Morgan

  27. Assessing Locomotor-Stimulating Effects of Cocaine in Rodents

    Article • December 2011, Springer Science + Business Media

    Drake Morgan

  28. Group Processes: Social Dominance

    Article • September 2011, Oxford University Press (OUP)

    Drake Morgan

  29. Usefulness of Preclinical Models for Assessing the Efficacy of Late-Life Interventions for Sarcopenia

    Article • The Journals of Gerontology Series A, June 2011, Oxford University Press (OUP)

    Drake Morgan

  30. Animal Models of Addiction: Fat and Sugar

    Article • Current Pharmaceutical Design, April 2011, Bentham Science Publishers

    Drake Morgan

  31. Effects of chronic fentanyl administration on physical performance of aged rats

    Article • Experimental Gerontology, January 2011, Elsevier

    Drake Morgan

  32. Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 × Brown Norway rats

    Article • AGE, December 2010, Springer Science + Business Media

    Drake Morgan

  33. Gene expression changes in the medial prefrontal cortex and nucleus accumbens following abstinence from cocaine self-administration

    Article • BMC Neuroscience, January 2010, Springer Science + Business Media

    Dr Willard M Freeman, Drake Morgan

  34. Persistent proteomic alterations in the medial prefrontal cortex with abstinence from cocaine self-administration

    Article • PROTEOMICS - CLINICAL APPLICATIONS, April 2009, Wiley

    Dr Willard M Freeman, Drake Morgan

  35. Evaluation of prescription opioids using operant-based pain measures in rats.

    Article • Experimental and Clinical Psychopharmacology, October 2008, American Psychological Association (APA)

    Drake Morgan

  36. Cocaine self-administration on a hold-down schedule of reinforcement in rats

    Article • Psychopharmacology, September 2008, Springer Science + Business Media

    Drake Morgan

  37. How to make a rat addicted to cocaine

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, November 2007, Elsevier

    Drake Morgan

  38. Persistent Alterations in Mesolimbic Gene Expression with Abstinence from Cocaine Self-Administration

    Article • Neuropsychopharmacology, September 2007, Nature

    Dr Willard M Freeman, Drake Morgan

  39. Cross-sensitization of the reinforcing effects of cocaine and amphetamine in rats

    Article • Psychopharmacology, August 2007, Springer Science + Business Media

    Drake Morgan

  40. Explaining the Escalation of Drug Use in Substance Dependence: Models and Appropriate Animal Laboratory Tests

    Article • Pharmacology, January 2007, Karger Publishers

    Drake Morgan

  41. PET imaging of dopamine D2 receptors during chronic cocaine self-administration in monkeys

    Article • Nature Neuroscience, July 2006, Springer Science + Business Media

    Robert H. Mach, Drake Morgan

  42. Discrete-trials heroin self-administration produces sensitization to the reinforcing effects of cocaine in rats

    Article • Psychopharmacology, January 2006, Springer Science + Business Media

    Drake Morgan

  43. Sensitization of the reinforcing effects of self-administered cocaine in rats: effects of dose and intravenous injection speed

    Article • European Journal of Neuroscience, July 2005, Wiley

    Drake Morgan

  44. Rapid and Persistent Sensitization to the Reinforcing Effects of Cocaine

    Article • Neuropsychopharmacology, May 2005, Springer Science + Business Media

    Drake Morgan

  45. Reduced Dopamine Terminal Function and Insensitivity to Cocaine Following Cocaine Binge Self-Administration and Deprivation

    Article • Neuropsychopharmacology, February 2005, Springer Science + Business Media

    Drake Morgan

  46. Effects of extended-access self-administration and deprivation on breakpoints maintained by cocaine in rats

    Article • Psychopharmacology, January 2005, Springer Science + Business Media

    Drake Morgan

  47. Extended cocaine self-administration and deprivation produces region-specific and time-dependent changes in connexin36 expression in rat brain

    Article • Synapse, January 2005, Wiley

    Drake Morgan

  48. Comparison of the Reinforcing Effects of Cocaine and Cocaine/Heroin Combinations under Progressive Ratio and Choice Schedules in Rats

    Article • Neuropsychopharmacology, December 2004, Springer Science + Business Media

    Drake Morgan

  49. Fast onset of dopamine uptake inhibition by intravenous cocaine

    Article • European Journal of Neuroscience, November 2004, Wiley

    Drake Morgan

  50. Binge self-administration and deprivation produces sensitization to the reinforcing effects of cocaine in rats

    Article • Psychopharmacology, August 2004, Springer Science + Business Media

    Drake Morgan

  51. Effects of positive allosteric modulators of the GABA B receptor on cocaine self-administration in rats

    Article • Psychopharmacology, April 2004, Springer Science + Business Media

    Drake Morgan

  52. Characterization of dopamine D1 and D2 receptor function in socially housed cynomolgus monkeys self-administering cocaine

    Article • Psychopharmacology, February 2004, Springer Science + Business Media

    Drake Morgan

  53. Effects of the dopamine reuptake inhibitor PTT on reinstatement and on food- and cocaine-maintained responding in rhesus monkeys

    Article • Psychopharmacology, January 2004, Springer Science + Business Media

    Drake Morgan

  54. Sensitization to the reinforcing effects of cocaine following binge-abstinent self-administration

    Article • Neuroscience & Biobehavioral Reviews, January 2004, Elsevier

    Drake Morgan

  55. Effect of strain and sex on μ opioid receptor-mediated G-protein activation in rat brain

    Article • Brain Research Bulletin, May 2003, Elsevier

    Drake Morgan

  56. The Reinforcing Efficacy of the Dopamine Reuptake Inhibitor 2β-Propanoyl-3β-(4-tolyl)-tropane (PTT) as Measured by a Progressive-Ratio Schedule and a Choice Procedure in Rhesus Monkeys

    Article • Journal of Pharmacology and Experimental Therapeutics, November 2002, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Drake Morgan

  57. Cocaine- and food-maintained responding under a multiple schedule in rhesus monkeys: environmental context and the effects of a dopamine antagonist

    Article • Psychopharmacology, October 2002, Springer Science + Business Media

    Robert H. Mach, Drake Morgan

  58. Social dominance in monkeys: dopamine D2 receptors and cocaine self-administration

    Article • Nature Neuroscience, January 2002, Springer Science + Business Media

    Robert H. Mach, Drake Morgan

  59. Cocaine-like discriminative stimulus effects and [ 3 H]dopamine uptake inhibition produced by selected partial opioid agonists

    Article • Behavioural Pharmacology, July 2001, Wolters Kluwer Health

    Drake Morgan

  60. Effects of Neuropeptide Y on the Discriminative Stimulus and Antinociceptive Properties of Morphine

    Article • Pharmacology Biochemistry and Behavior, September 1999, Elsevier

    Drake Morgan

  61. An Examination of the Interactions Between the Antinociceptive Effects of Morphine and Various [micro sign]-Opioids

    Article • Anesthesia & Analgesia, February 1999, Wolters Kluwer Health

    Drake Morgan

  62. An Examination of the Interactions Between the Antinociceptive Effects of Morphine and Various [micro sign]-Opioids

    Article • Anesthesia & Analgesia, February 1999, Wolters Kluwer Health

    Drake Morgan

  63. The � opioid irreversible antagonist beta-funaltrexamine differentiates the discriminative stimulus effects of opioids with high and low efficacy at the ? opioid receptor

    Article • Psychopharmacology, November 1998, Springer Science + Business Media

    Drake Morgan

  64. Opioids and rate of positively reinforced behavior: II. Antagonism by β-funaltrexamine.

    Article • Experimental and Clinical Psychopharmacology, November 1996, American Psychological Association (APA)

    Drake Morgan

  65. Effects of the delta opioid agonist BW373U86 in pigeons trained to discriminate fentanyl, bremazocine and water in a three-choice drug discrimination procedure

    Article • Psychopharmacology, August 1996, Springer Science + Business Media

    Drake Morgan

  66. Contribution of individual differences to discriminative stimulus, antinociceptive and rate-decreasing effects of opioids

    Article • Behavioural Pharmacology, May 1996, Wolters Kluwer Health

    Drake Morgan

  67. Opioids and rate of positively reinforced behavior

    Article • Behavioural Pharmacology, May 1996, Wolters Kluwer Health

    Drake Morgan

  68. Discriminative stimulus effects of the 5HT1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids

    Article • Psychopharmacology, December 1995, Springer Science + Business Media

    Drake Morgan

  69. Assessment of the relative intrinsic efficacy of profadol and meperidine in a pigeon drug discrimination procedure

    Article • Behavioural Pharmacology, February 1994, Wolters Kluwer Health

    Drake Morgan