All Stories

  1. Hydrophobic unnatural base pair promotes trigger loop closure and catalysis in cellular RNA polymerase independent of hydrogen bonding

    Article • Proceedings of the National Academy of Sciences, August 2026, Proceedings of the National Academy of Sciences

    Dong Wang

  2. Structural basis of transcription-coupled RNA damage by incorporation of oxidized ribonucleotides

    Article • Proceedings of the National Academy of Sciences, April 2026, Proceedings of the National Academy of Sciences

    Dong Wang

  3. RNA polymerase II trapped on a molecular treadmill: Structural basis of persistent transcriptional arrest by a minor groove DNA binder

    Article • Proceedings of the National Academy of Sciences, January 2022, Proceedings of the National Academy of Sciences

    Dong Wang

  4. Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers

    Article • Proceedings of the National Academy of Sciences, September 2020, Proceedings of the National Academy of Sciences

    Dong Wang

  5. A chemical probe targets DNA 5-formylcytosine sites and inhibits TDG excision, polymerases bypass, and gene expression

    Article • Chemical Science, January 2014, Royal Society of Chemistry

    Dong Wang, Dr CHAO ZHANG