All Stories

  1. AV-101, a Pro-Drug Antagonist at the NMDA Receptor Glycine Site, Reduces L-Dopa Induced Dyskinesias in MPTP Monkeys

    Article • Cells, November 2022, MDPI AG

    Dr David Dickens

  2. LAT1, a novel pharmacological target for the treatment of glioblastoma

    Article • Biochemical Pharmacology, July 2022, Elsevier

    Dr David Dickens

  3. The dipeptide prolyl-hydroxyproline promotes cellular homeostasis and lamellipodia-driven motility via active β1-integrin in adult tendon cells

    Article • Journal of Biological Chemistry, July 2021, Elsevier

    Dr David Dickens

  4. Inflammatory Bowel Disease: A Personalized Approach

    Article • Frontiers in Pediatrics, February 2021, Frontiers

    Dr David Dickens

  5. Probenecid Increases the Concentration of 7-Chlorokynurenic Acid Derived from the Prodrug 4-Chlorokynurenine within the Prefrontal Cortex

    Article • Molecular Pharmaceutics, December 2020, American Chemical Society (ACS)

    Dr David Dickens

  6. Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants

    Article • Archives of Toxicology, June 2020, Springer Science + Business Media

    Dr David Dickens

  7. Cellular uptake of the atypical antipsychotic clozapine is a carrier-mediated process

    Article • Molecular Pharmaceutics, June 2018, American Chemical Society (ACS)

    Dr David Dickens

  8. In vitro characterisation of solid drug nanoparticle compositions of efavirenz in a brain endothelium cell line

    Article • Journal of Interdisciplinary Nanomedicine, September 2017, Wiley

    Professor Steven P Rannard, Dr David Dickens, Neill Liptrott, Alison Savage, James Hobson

  9. Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol

    Article • Scientific Reports, March 2017, Nature

    Dr David Dickens

  10. Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography

    Article • Journal of Medicinal Chemistry, August 2015, American Chemical Society (ACS)

    Dr David Dickens

  11. Misoprostol-induced fever and genetic polymorphisms in drug transporters SLCO1B1 and ABCC4 in women of Latin American and European ancestry

    Article • Pharmacogenomics, June 2015, Future Medicine

    Professor Andrew David Weeks, Dr David Dickens

  12. A comprehensive functional and clinical analysis of ABCC2 and its impact on treatment response to carbamazepine

    Article • The Pharmacogenomics Journal, February 2014, Nature

    Dr David Dickens

  13. Transport of gabapentin by LAT1 (SLC7A5)

    Article • Biochemical Pharmacology, June 2013, Elsevier

    Dr David Dickens, Dr Svetlana Antonyuk

  14. ABCB1 single nucleotide polymorphisms (1236C>T, 2677G>T, and 3435C>T) do not affect transport activity of human P-glycoprotein

    Article • Pharmacogenetics and Genomics, June 2013, Wolters Kluwer Health

    Dr David Dickens

  15. A Multi-System Approach Assessing the Interaction of Anticonvulsants with P-gp

    Article • PLoS ONE, May 2013, PLOS

    Dr David Dickens

  16. Lamotrigine is a substrate for OCT1 in brain endothelial cells

    Article • Biochemical Pharmacology, March 2012, Elsevier

    Dr David Dickens

  17. The B-cell lymphoma 2 (BCL2)-inhibitors, ABT-737 and ABT-263, are substrates for P-glycoprotein

    Article • Biochemical and Biophysical Research Communications, May 2011, Elsevier

    Dr David Dickens

  18. MAP4K3 modulates cell death via the post-transcriptional regulation of BH3-only proteins

    Article • Proceedings of the National Academy of Sciences, July 2009, Proceedings of the National Academy of Sciences

    Dr David Dickens

  19. Chapter 5. Drug Transporters at the Blood–Brain Barrier

    Article • Royal Society of Chemistry

    Dr David Dickens