All Stories

  1. Pierre Chambon, a pioneer of molecular biology and gene regulation in eukaryotes

    Article • Proceedings of the National Academy of Sciences, July 2026, Proceedings of the National Academy of Sciences

    Daniel Metzger

  2. HIF1 inhibition targets tumoral and myeloid cells, and is a promising therapy for metastatic castration-resistant prostate cancer

    Article • Cell Death and Disease, March 2026, Springer Science + Business Media

    Daniel Metzger

  3. Nouvelles perspectives de traitement du cancer de la prostate basé sur la vitamine D

    Article • médecine/sciences, February 2025, EDP Sciences

    Daniel Metzger

  4. Espoir d’un nouveau traitement pour le cancer de la prostate résistant à la castration

    Article • médecine/sciences, October 2023, EDP Sciences

    Daniel Metzger

  5. Hypoxia‐inducible factor 1A inhibition overcomes castration resistance of prostate tumors

    Article • EMBO Molecular Medicine, April 2023, Springer Science + Business Media

    Daniel Metzger

  6. Vitamin D Analogs Bearing C-20 Modifications Stabilize the Agonistic Conformation of Non-Responsive Vitamin D Receptor Variants

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    Daniel Metzger

  7. Single-cell analyses unravel cell type–specific responses to a vitamin D analog in prostatic precancerous lesions

    Article • Science Advances, July 2021, American Association for the Advancement of Science

    Daniel Metzger

  8. Tyrosine hydroxylase conditional KO mice reveal peripheral tissue-dependent differences in dopamine biosynthetic pathways

    Article • Journal of Biological Chemistry, January 2021, Elsevier

    Daniel Metzger

  9. Cytosolic sequestration of the vitamin D receptor as a therapeutic option for vitamin D-induced hypercalcemia

    Article • Nature Communications, December 2020, Springer Science + Business Media

    Daniel Metzger

  10. Aging Exacerbates Ischemia-Reperfusion-Induced Mitochondrial Respiration Impairment in Skeletal Muscle

    Article • Antioxidants, June 2019, MDPI AG

    Daniel Metzger

  11. Skeletal Muscle–Specific Activation of Gq Signaling Maintains Glucose Homeostasis

    Article • Diabetes, April 2019, American Diabetes Association

    Daniel Metzger

  12. PGC-1β modulates statin-associated myotoxicity in mice

    Article • Archives of Toxicology, December 2018, Springer Science + Business Media

    Daniel Metzger

  13. Senescence controls prostatic neoplasia driven by Pten loss

    Article • Molecular & Cellular Oncology, November 2018, Taylor & Francis

    Daniel Metzger

  14. Comment limiter la progression des tumeurs prostatiques déficientes en PTEN ?

    Article • médecine/sciences, November 2018, EDP Sciences

    Daniel Metzger

  15. Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver

    Article • Cell Metabolism, August 2018, Elsevier

    Daniel Metzger

  16. Diabetes Worsens Skeletal Muscle Mitochondrial Function, Oxidative Stress, and Apoptosis After Lower-Limb Ischemia-Reperfusion: Implication of the RISK and SAFE Pathways?

    Article • Frontiers in Physiology, May 2018, Frontiers

    Daniel Metzger

  17. PTEN deletion in luminal cells of mature prostate induces replication stress and senescence in vivo

    Article • Journal of Experimental Medicine, May 2018, Rockefeller University Press

    Daniel Metzger

  18. γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor

    Article • Cell Metabolism, April 2018, Elsevier

    Daniel Metzger

  19. Ligand-Independent Actions of Vitamin D Receptor

    Article • January 2018, Elsevier

    Daniel Metzger

  20. The histone code reader Spin1 controls skeletal muscle development

    Article • Cell Death and Disease, November 2017, Springer Science + Business Media

    Daniel Metzger

  21. Improved Protocol for Chromatin Immunoprecipitation from Mouse Skeletal Muscle

    Article • Journal of Visualized Experiments, November 2017, MyJove Corporation

    Daniel Metzger

  22. Peroxisome proliferator‐activated receptor gamma (PPARγ) regulates lactase expression and activity in the gut

    Article • EMBO Molecular Medicine, September 2017, EMBO

    Daniel Metzger, Laurent Dubuquoy

  23. Moderate Exercise Allows for shorter Recovery Time in Critical Limb Ischemia

    Article • Frontiers in Physiology, July 2017, Frontiers

    Daniel Metzger

  24. BRG1-SWI/SNF-dependent regulation of the Wt1 transcriptional landscape mediates epicardial activity during heart development and disease

    Article • Nature Communications, July 2017, Springer Science + Business Media

    Daniel Metzger

  25. Conditional expression of Ki-RasG12V in the mammary epithelium of transgenic mice induces estrogen receptor alpha (ERα)-positive adenocarcinoma

    Article • Oncogene, July 2017, Springer Science + Business Media

    Daniel Metzger

  26. Gonad-related factors promote muscle performance gain during postnatal development in male and female mice

    Article • AJP Endocrinology and Metabolism, July 2017, American Physiological Society

    Daniel Metzger

  27. IFN-β-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis

    Article • Acta Neuropathologica, June 2017, Springer Science + Business Media

    Daniel Metzger

  28. Androgen signaling negatively controls group 2 innate lymphoid cells

    Article • Journal of Experimental Medicine, May 2017, Rockefeller University Press

    Daniel Metzger

  29. The Nuclear Receptor Nr4a1 Acts as a Microglia Rheostat and Serves as a Therapeutic Target in Autoimmune-Driven Central Nervous System Inflammation

    Article • The Journal of Immunology, May 2017, Oxford University Press (OUP)

    Daniel Metzger

  30. Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice

    Article • PLOS One, February 2017, PLOS

    Daniel Metzger

  31. Muscle expression of a malonyl-CoA-insensitive carnitine palmitoyltransferase-1 protects mice against high-fat/high-sucrose diet-induced insulin resistance

    Article • AJP Endocrinology and Metabolism, September 2016, American Physiological Society

    Daniel Metzger

  32. Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis

    Article • Journal of Clinical Investigation, July 2016, American Society for Clinical Investigation

    Professor Dianhua Jiang, Daniel Metzger

  33. The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles

    Article • Nature Communications, December 2015, Springer Science + Business Media

    Daniel Metzger

  34. Patrolling monocytes control tumor metastasis to the lung

    Article • Science, November 2015, American Association for the Advancement of Science

    Daniel Metzger

  35. VDR and gemini ligands

    Article • Oncotarget, September 2015, Impact Journals, LLC

    Daniel Metzger

  36. A New Murine Model of Sustainable and Durable Chronic Critical Limb Ischemia Fairly Mimicking Human Pathology

    Article • European Journal of Vascular and Endovascular Surgery, February 2015, Elsevier

    Daniel Metzger

  37. A Vitamin D Receptor Selectively Activated by Gemini Analogs Reveals Ligand Dependent and Independent Effects

    Article • Cell Reports, February 2015, Elsevier

    Daniel Metzger

  38. The Orphan Nuclear Receptor Nur77 Is a Determinant of Myofiber Size and Muscle Mass in Mice

    Article • Molecular and Cellular Biology, January 2015, ASM Journals

    Daniel Metzger

  39. Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis

    Article • Nature Medicine, January 2015, Springer Science + Business Media

    Daniel Metzger

  40. Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling

    Article • Journal of Clinical Investigation, January 2015, American Society for Clinical Investigation

    Daniel Metzger

  41. Clearance of PML/RARA-bound promoters suffice to initiate APL differentiation

    Article • Blood, December 2014, American Society of Hematology

    Daniel Metzger

  42. Myofiber Androgen Receptor Promotes Maximal Mechanical Overload-Induced Muscle Hypertrophy and Fiber Type Transition in Male Mice

    Article • Endocrinology, December 2014, Endocrine Society

    Daniel Metzger

  43. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type

    Article • Developmental Cell, December 2014, Elsevier

    Daniel Metzger

  44. Acute effect of androgens on maximal force-generating capacity and electrically evoked calcium transient in mouse skeletal muscles

    Article • Steroids, September 2014, Elsevier

    Daniel Metzger

  45. Mammary stem cells have myoepithelial cell properties

    Article • Nature Cell Biology, August 2014, Springer Science + Business Media

    Daniel Metzger

  46. Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine

    Article • PLoS Genetics, July 2014, PLOS

    Daniel Metzger

  47. LSD1 promotes oxidative metabolism of white adipose tissue

    Article • Nature Communications, June 2014, Springer Science + Business Media

    Daniel Metzger

  48. Skeletal myofiber VEGF is essential for the exercise training response in adult mice

    Article • AJP Regulatory Integrative and Comparative Physiology, April 2014, American Physiological Society

    Daniel Metzger

  49. Lysine-specific demethylase 1 regulates differentiation onset and migration of trophoblast stem cells

    Article • Nature Communications, January 2014, Springer Science + Business Media

    Daniel Metzger

  50. Nurr1 expression is regulated by voltage-dependent calcium channels and calcineurin in cultured hippocampal neurons

    Article • Neuroscience Letters, January 2014, Elsevier

    Daniel Metzger

  51. Prokineticin Receptor 1 as a Novel Suppressor of Preadipocyte Proliferation and Differentiation to Control Obesity

    Article • PLOS One, December 2013, PLOS

    Dr Mounia Boulberdaa, Daniel Metzger

  52. The BAF Complex Interacts with Pax6 in Adult Neural Progenitors to Establish a Neurogenic Cross-Regulatory Transcriptional Network

    Article • Cell Stem Cell, October 2013, Elsevier

    Daniel Metzger

  53. Retinoid Signaling in Progenitors Controls Specification and Regeneration of the Urothelium

    Article • Developmental Cell, September 2013, Elsevier

    Daniel Metzger

  54. Knockdown of parathyroid hormone related protein in smooth muscle cells alters renal hemodynamics but not blood pressure

    Article • AJP Renal Physiology, August 2013, American Physiological Society

    Daniel Metzger

  55. 180 PPARγ Is a Master Regulator of Lactase Production by Intestinal Epithelial Cells

    Article • Gastroenterology, May 2013, Elsevier

    Daniel Metzger

  56. Smoothened is a master regulator of adult liver repair

    Article • Journal of Clinical Investigation, April 2013, American Society for Clinical Investigation

    Daniel Metzger

  57. Vitamin D Receptor in Osteoblasts Is a Negative Regulator of Bone Mass Control

    Article • Endocrinology, March 2013, Endocrine Society

    Daniel Metzger

  58. Genetically engineered mouse models of prostate cancer

    Article • Molecular Oncology, February 2013, Wiley

    Daniel Metzger

  59. Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis

    Article • Nature Immunology, January 2013, Springer Science + Business Media

    Daniel Metzger

  60. Skeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension

    Article • Molecular and Cellular Biochemistry, October 2012, Springer Science + Business Media

    Daniel Metzger

  61. PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice

    Article • Journal of Clinical Investigation, October 2012, American Society for Clinical Investigation

    Daniel Metzger

  62. Polyphenols prevent ageing‐related impairment in skeletal muscle mitochondrial function through decreased reactive oxygen species production

    Article • Experimental Physiology, October 2012, Wiley

    Daniel Metzger

  63. Cell Autonomous Lipin 1 Function Is Essential for Development and Maintenance of White and Brown Adipose Tissue

    Article • Molecular and Cellular Biology, October 2012, ASM Journals

    Daniel Metzger

  64. The nuclear hormone receptor PPARγ counteracts vascular calcification by inhibiting Wnt5a signalling in vascular smooth muscle cells

    Article • Nature Communications, September 2012, Springer Science + Business Media

    Daniel Metzger

  65. Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

    Article • Nature Medicine, August 2012, Springer Science + Business Media

    Dr Paulo Wagner Pires, Daniel Metzger

  66. Temporally controlled targeted somatic mutagenesis in mouse eye pigment epithelium

    Article • genesis, July 2012, Wiley

    Daniel Metzger

  67. Chromatin-Remodeling Factor Brg1 Is Required for Schwann Cell Differentiation and Myelination

    Article • Developmental Cell, July 2012, Elsevier

    Daniel Metzger

  68. Relevance of Exocytotic Glutamate Release from Retinal Glia

    Article • Neuron, May 2012, Elsevier

    Daniel Metzger

  69. Compensatory Regulation of Dopamine after Ablation of the Tyrosine Hydroxylase Gene in the Nigrostriatal Projection

    Article • Journal of Biological Chemistry, December 2011, Elsevier

    Daniel Metzger

  70. Aggravated TSLP-Induced Atopic Dermatitis in Mice Lacking Dicer in Adult Skin Keratinocytes

    Article • Journal of Investigative Dermatology, November 2011, Elsevier

    Daniel Metzger

  71. Regenerated Luminal Epithelial Cells Are Derived from Preexisting Luminal Epithelial Cells in Adult Mouse Prostate

    Article • Molecular Endocrinology, November 2011, Endocrine Society

    Daniel Metzger

  72. Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis

    Article • Hepatology, August 2011, Wolters Kluwer Health

    Daniel Metzger

  73. SWI/SNF Complexes Containing Brahma or Brahma-Related Gene 1 Play Distinct Roles in Smooth Muscle Development

    Article • Molecular and Cellular Biology, April 2011, ASM Journals

    Daniel Metzger

  74. The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells

    Article • Nature Communications, April 2011, Springer Science + Business Media

    Daniel Metzger

  75. Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor

    Article • Cell, April 2011, Elsevier

    Daniel Metzger

  76. Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer

    Article • Proceedings of the National Academy of Sciences, March 2011, Proceedings of the National Academy of Sciences

    Daniel Metzger

  77. Generation of Spatio‐Temporally Controlled Targeted Somatic Mutations in the Mouse

    Article • Current Protocols in Mouse Biology, March 2011, Wiley

    Daniel Metzger

  78. Chromatin remodelling complex dosage modulates transcription factor function in heart development

    Article • Nature Communications, February 2011, Springer Science + Business Media

    Daniel Metzger

  79. Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation

    Article • Epigenetics & Chromatin, November 2010, Springer Science + Business Media

    Daniel Metzger

  80. The Transcriptional Coregulators TIF2 and SRC-1 Regulate Energy Homeostasis by Modulating Mitochondrial Respiration in Skeletal Muscles

    Article • Cell Metabolism, November 2010, Elsevier

    Daniel Metzger

  81. Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells

    Article • Nucleic Acids Research, October 2010, Oxford University Press (OUP)

    Daniel Metzger

  82. Myocytic androgen receptor controls the strength but not the mass of limb muscles

    Article • Proceedings of the National Academy of Sciences, July 2010, Proceedings of the National Academy of Sciences

    Daniel Metzger

  83. Inflammatory Mediator TAK1 Regulates Hair Follicle Morphogenesis and Anagen Induction Shown by Using Keratinocyte-Specific TAK1-Deficient Mice

    Article • PLOS One, June 2010, PLOS

    Daniel Metzger

  84. Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

    Article • Oncogene, March 2010, Springer Science + Business Media

    Daniel Metzger

  85. Epidermal γδ T cells sense precancerous cellular dysregulation and initiate immune responses

    Article • International Immunology, February 2010, Oxford University Press (OUP)

    Daniel Metzger

  86. Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy

    Article • Journal of Biological Chemistry, February 2010, Elsevier

    Daniel Metzger

  87. Nurr1 Is Required for Maintenance of Maturing and Adult Midbrain Dopamine Neurons

    Article • Journal of Neuroscience, December 2009, Society for Neuroscience

    Daniel Metzger

  88. Autophagy Is Required to Maintain Muscle Mass

    Article • Cell Metabolism, December 2009, Elsevier

    Daniel Metzger

  89. Oncogenesis Caused by Loss of the SNF5 Tumor Suppressor Is Dependent on Activity of BRG1, the ATPase of the SWI/SNF Chromatin Remodeling Complex

    Article • Cancer Research, October 2009, American Association for Cancer Research (AACR)

    Daniel Metzger

  90. Corneodesmosin gene ablation induces lethal skin-barrier disruption and hair-follicle degeneration related to desmosome dysfunction

    Article • Journal of Cell Science, August 2009, The Company of Biologists

    Daniel Metzger

  91. SWI/SNF Deficiency Results in Aberrant Chromatin Organization, Mitotic Failure, and Diminished Proliferative Capacity

    Article • Molecular Biology of the Cell, July 2009, American Society for Cell Biology (ASCB)

    Daniel Metzger

  92. Dual Role of COUP-TF-Interacting Protein 2 in Epidermal Homeostasis and Permeability Barrier Formation

    Article • Journal of Investigative Dermatology, June 2009, Elsevier

    Daniel Metzger

  93. Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis

    Article • Proceedings of the National Academy of Sciences, March 2009, Proceedings of the National Academy of Sciences

    Daniel Metzger

  94. Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma

    Article • Proceedings of the National Academy of Sciences, February 2009, Proceedings of the National Academy of Sciences

    Daniel Metzger

  95. Induction of Thymic Stromal Lymphopoietin Expression in Keratinocytes Is Necessary for Generating an Atopic Dermatitis upon Application of the Active Vitamin D3 Analogue MC903 on Mouse Skin

    Article • Journal of Investigative Dermatology, February 2009, Elsevier

    Daniel Metzger

  96. LRP1 Controls Intracellular Cholesterol Storage and Fatty Acid Synthesis through Modulation of Wnt Signaling

    Article • Journal of Biological Chemistry, January 2009, Elsevier

    Daniel Metzger

  97. Premature Aging in Skeletal Muscle Lacking Serum Response Factor

    Article • PLOS One, December 2008, PLOS

    Daniel Metzger

  98. Efficient temporally‐controlled targeted mutagenesis in smooth muscle cells of the adult mouse

    Article • genesis, October 2008, Wiley

    Daniel Metzger

  99. Targeted Knockout of BRG1 Potentiates Lung Cancer Development

    Article • Cancer Research, May 2008, American Association for Cancer Research (AACR)

    Daniel Metzger

  100. Cutaneous cancer stem cell maintenance is dependent on β-catenin signalling

    Article • Nature, April 2008, Springer Science + Business Media

    Daniel Metzger

  101. Temporally controlled ablation of PTEN in adult mouse prostate epithelium generates a model of invasive prostatic adenocarcinoma

    Article • Proceedings of the National Academy of Sciences, February 2008, Proceedings of the National Academy of Sciences

    Daniel Metzger

  102. TGF-β superfamily signaling is essential for tooth and hair morphogenesis and differentiation

    Article • European Journal of Cell Biology, December 2007, Elsevier

    Daniel Metzger

  103. Loss of Trim24 (Tif1α) gene function confers oncogenic activity to retinoic acid receptor alpha

    Article • Nature Genetics, November 2007, Springer Science + Business Media

    Daniel Metzger

  104. Compromised Intestinal Lipid Absorption in Mice with a Liver-Specific Deficiency of Liver Receptor Homolog 1

    Article • Molecular and Cellular Biology, October 2007, ASM Journals

    Sander Houten, Daniel Metzger

  105. Apoptotic Extinction of Germ Cells in Testes ofCyp26b1Knockout Mice

    Article • Endocrinology, October 2007, Endocrine Society

    Daniel Metzger

  106. Transgenic mice for conditional gene manipulation in astroglial cells

    Article • Glia, September 2007, Wiley

    Daniel Metzger

  107. Estrogen Prevents Bone Loss via Estrogen Receptor α and Induction of Fas Ligand in Osteoclasts

    Article • Cell, September 2007, Elsevier

    Daniel Metzger

  108. The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

    Article • Development, August 2007, The Company of Biologists

    Daniel Metzger

  109. LRH-1-mediated glucocorticoid synthesis in enterocytes protects against inflammatory bowel disease

    Article • Proceedings of the National Academy of Sciences, August 2007, Proceedings of the National Academy of Sciences

    Laurent Dubuquoy, Daniel Metzger

  110. Adipose tissue-specific inactivation of the retinoblastoma protein protects against diabesity because of increased energy expenditure

    Article • Proceedings of the National Academy of Sciences, June 2007, Proceedings of the National Academy of Sciences

    Daniel Metzger

  111. IL‐13 induces expression of CD36 in human monocytes through PPARγ activation

    Article • European Journal of Immunology, May 2007, Wiley

    Daniel Metzger

  112. Malignant Transformation of DMBA/TPA-Induced Papillomas and Nevi in the Skin of Mice Selectively Lacking Retinoid-X-Receptor α in Epidermal Keratinocytes

    Article • Journal of Investigative Dermatology, May 2007, Elsevier

    Daniel Metzger

  113. PGC1α expression is controlled in skeletal muscles by PPARβ, whose ablation results in fiber-type switching, obesity, and type 2 diabetes

    Article • Cell Metabolism, November 2006, Elsevier

    Daniel Metzger

  114. LPS-induced TNF-α factor (LITAF)-deficient mice express reduced LPS-induced cytokine: Evidence for LITAF-dependent LPS signaling pathways

    Article • Proceedings of the National Academy of Sciences, September 2006, Proceedings of the National Academy of Sciences

    Daniel Metzger

  115. Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis

    Article • Proceedings of the National Academy of Sciences, August 2006, Proceedings of the National Academy of Sciences

    Daniel Metzger

  116. Skin epidermis lacking the c-myc gene is resistant to Ras-driven tumorigenesis but can reacquire sensitivity upon additional loss of the p21 Cip1 gene

    Article • Genes & Development, August 2006, Cold Spring Harbor Laboratory Press

    Daniel Metzger

  117. Genetic and pharmacological evidence that a retinoic acid cannot be the RXR-activating ligand in mouse epidermis keratinocytes

    Article • Genes & Development, June 2006, Cold Spring Harbor Laboratory Press

    Daniel Metzger

  118. Temporal regulation of Cre recombinase activity in neural stem cells

    Article • genesis, May 2006, Wiley

    Daniel Metzger

  119. Localized Inflammatory Skin Disease Following Inducible Ablation of I Kappa B Kinase 2 in Murine Epidermis

    Article • Journal of Investigative Dermatology, March 2006, Elsevier

    Daniel Metzger

  120. Skin lesion development in a mouse model of incontinentia pigmenti is triggered by NEMO deficiency in epidermal keratinocytes and requires TNF signaling

    Article • Human Molecular Genetics, January 2006, Oxford University Press (OUP)

    Daniel Metzger

  121. Brg1 is required for murine neural stem cell maintenance and gliogenesis

    Article • Developmental Biology, January 2006, Elsevier

    Daniel Metzger

  122. Viral-Mediated Temporally Controlled Dopamine Production in a Rat Model of Parkinson Disease

    Article • Molecular Therapy, January 2006, Elsevier

    Daniel Metzger

  123. Premature ovarian failure in androgen receptor-deficient mice

    Article • Proceedings of the National Academy of Sciences, December 2005, Proceedings of the National Academy of Sciences

    Daniel Metzger

  124. Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency

    Article • Journal of Investigative Dermatology, December 2005, Elsevier

    Daniel Metzger

  125. Temporally controlled targeted somatic mutagenesis in embryonic surface ectoderm and fetal epidermal keratinocytes unveils two distinct developmental functions of BRG1 in limb morphogenesis and skin barrier formation

    Article • Development, October 2005, The Company of Biologists

    Daniel Metzger

  126. Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin

    Article • Proceedings of the National Academy of Sciences, September 2005, Proceedings of the National Academy of Sciences

    Daniel Metzger

  127. TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis

    Article • Developmental Biology, September 2005, Elsevier

    Laszlo Tora, Daniel Metzger

  128. Functional role of RXRs and PPARγ in mature adipocytes

    Article • Prostaglandins Leukotrienes and Essential Fatty Acids, July 2005, Elsevier

    Daniel Metzger

  129. Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ

    Article • Journal of Experimental Medicine, April 2005, Rockefeller University Press

    Laurent Dubuquoy, Daniel Metzger

  130. Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse

    Article • genesis, January 2005, Wiley

    Daniel Metzger

  131. Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression

    Article • Genes & Development, December 2004, Cold Spring Harbor Laboratory Press

    Daniel Metzger

  132. Altered Growth in Male Peroxisome Proliferator-Activated Receptor γ (PPARγ) Heterozygous Mice: Involvement of PPARγ in a Negative Feedback Regulation of Growth Hormone Action

    Article • Molecular Endocrinology, October 2004, Endocrine Society

    Daniel Metzger

  133. Peroxisome-Proliferator-Activated Receptor (PPAR)-γ Activation Stimulates Keratinocyte Differentiation

    Article • Journal of Investigative Dermatology, August 2004, Elsevier

    Daniel Metzger

  134. Efficient temporally controlled targeted somatic mutagenesis in hepatocytes of the mouse

    Article • genesis, July 2004, Wiley

    Daniel Metzger

  135. Tissue‐specific and inducible Cre‐mediated recombination in the gut epithelium

    Article • genesis, July 2004, Wiley

    Daniel Metzger

  136. EpithelialBmpr1aregulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development

    Article • Development, May 2004, The Company of Biologists

    Daniel Metzger

  137. In vivo activation of PPAR target genes by RXR homodimers

    Article • The EMBO Journal, April 2004, Springer Science + Business Media

    Daniel Metzger

  138. Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse

    Article • Proceedings of the National Academy of Sciences, March 2004, Proceedings of the National Academy of Sciences

    Daniel Metzger

  139. Friedreich Ataxia Mouse Models with Progressive Cerebellar and Sensory Ataxia Reveal Autophagic Neurodegeneration in Dorsal Root Ganglia

    Article • Journal of Neuroscience, February 2004, Society for Neuroscience

    Daniel Metzger

  140. Retinal Dystrophy Resulting from Ablation of RXRα in the Mouse Retinal Pigment Epithelium

    Article • American Journal Of Pathology, February 2004, Elsevier

    Daniel Metzger

  141. Brain masculinization requires androgen receptor function

    Article • Proceedings of the National Academy of Sciences, January 2004, Proceedings of the National Academy of Sciences

    Daniel Metzger

  142. Hedgehog Signaling Regulates Sebaceous Gland Development

    Article • American Journal Of Pathology, December 2003, Elsevier

    Daniel Metzger

  143. Sequential Roles of Brg, the ATPase Subunit of BAF Chromatin Remodeling Complexes, in Thymocyte Development

    Article • Immunity, August 2003, Elsevier

    Daniel Metzger

  144. Suppressive function of androgen receptor in bone resorption

    Article • Proceedings of the National Academy of Sciences, July 2003, Proceedings of the National Academy of Sciences

    Daniel Metzger

  145. TAF10 (TAFII30) Is Necessary for TFIID Stability and Early Embryogenesis in Mice

    Article • Molecular and Cellular Biology, June 2003, ASM Journals

    Daniel Metzger

  146. Developing with lethal RA levels: genetic ablation ofRargcan restore the viability of mice lackingCyp26a1

    Article • Development, April 2003, The Company of Biologists

    Daniel Metzger

  147. Tamoxifen-inducible glia-specific Cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells

    Article • Molecular and Cellular Neuroscience, April 2003, Elsevier

    Daniel Metzger

  148. Temporally Controlled Site-Specific Mutagenesis in the Germ Cell Lineage of the Mouse Testis1

    Article • Biology of Reproduction, February 2003, Oxford University Press (OUP)

    Daniel Metzger

  149. Targeted Conditional Somatic Mutagenesis in the Mouse: Temporally-Controlled Knock Out of Retinoid Receptors in Epidermal Keratinocytes

    Article • January 2003, Elsevier

    Daniel Metzger

  150. Physiological and retinoid-induced proliferations of epidermis basal keratinocytes are differently controlled

    Article • The EMBO Journal, July 2002, Springer Science + Business Media

    Daniel Metzger

  151. Temporally controlled targeted somatic mutagenesis in the mouse brain

    Article • European Journal of Neuroscience, December 2001, Wiley

    Daniel Metzger

  152. Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPARβ mutant mice

    Article • Journal of Cell Biology, August 2001, Rockefeller University Press

    Daniel Metzger

  153. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

    Article • The EMBO Journal, July 2001, Springer Science + Business Media

    Daniel Metzger

  154. Site- and Time-Specific Gene Targeting in the Mouse

    Article • Methods, May 2001, Elsevier

    Daniel Metzger

  155. Selective ablation of retinoid X receptor α in hepatocytes impairs their lifespan and regenerative capacity

    Article • Proceedings of the National Academy of Sciences, April 2001, Proceedings of the National Academy of Sciences

    Daniel Metzger

  156. An efficient system for conditional gene expression in embryonic stem cells and in their in vitro and in vivo differentiated derivatives

    Article • Proceedings of the National Academy of Sciences, February 2001, Proceedings of the National Academy of Sciences

    Daniel Metzger

  157. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures

    Article • Genes & Development, January 2001, Cold Spring Harbor Laboratory Press

    Daniel Metzger

  158. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (Cre-ERT2) in adipocytes

    Article • Proceedings of the National Academy of Sciences, December 2000, Proceedings of the National Academy of Sciences

    Daniel Metzger

  159. A Brg1 Null Mutation in the Mouse Reveals Functional Differences among Mammalian SWI/SNF Complexes

    Article • Molecular Cell, December 2000, Elsevier

    Daniel Metzger

  160. F9 Embryonal Carcinoma Cells Engineered for Tamoxifen-Dependent Cre-Mediated Site-Directed Mutagenesis and Doxycycline-Inducible Gene Expression

    Article • Experimental Cell Research, November 2000, Elsevier

    Daniel Metzger

  161. Skin abnormalities generated by temporally controlled RXRα mutations in mouse epidermis

    Article • Nature, October 2000, Springer Science + Business Media

    Daniel Metzger

  162. Characterization of the Fasting-induced Adipose Factor FIAF, a Novel Peroxisome Proliferator-activated Receptor Target Gene

    Article • Journal of Biological Chemistry, September 2000, Elsevier

    Daniel Metzger

  163. p300 Mediates Functional Synergism between AF-1 and AF-2 of Estrogen Receptor α and β by Interacting Directly with the N-terminal A/B Domains

    Article • Journal of Biological Chemistry, May 2000, Elsevier

    Daniel Metzger

  164. Inducible site-specific somatic mutagenesis in mouse hepatocytes

    Article • genesis, February 2000, Wiley

    Daniel Metzger

  165. Temporally controlled somatic mutagenesis in smooth muscle

    Article • genesis, January 2000, Wiley

    Daniel Metzger

  166. Targeted Somatic Mutagenesis in Mouse Epidermis

    Article • Hormone Research in Paediatrics, January 2000, Karger Publishers

    Daniel Metzger

  167. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ERT and Cre-ERT2 recombinases

    Article • Nucleic Acids Research, November 1999, Oxford University Press (OUP)

    Daniel Metzger

  168. Engineering the mouse genome by site-specific recombination

    Article • Current Opinion in Biotechnology, October 1999, Elsevier

    Daniel Metzger

  169. Mammalian TAFII30 is required for cell cycle progression and specific cellular differentiation programmes

    Article • The EMBO Journal, September 1999, Springer Science + Business Media

    Daniel Metzger

  170. A chimeric Cre recombinase inducible by synthetic,but not by natural ligands of the glucocorticoid receptor

    Article • Nucleic Acids Research, September 1998, Oxford University Press (OUP)

    Daniel Metzger

  171. Mouse P450RAI (CYP26) Expression and Retinoic Acid-inducible Retinoic Acid Metabolism in F9 Cells Are Regulated by Retinoic Acid Receptor γ and Retinoid X Receptor α

    Article • Journal of Biological Chemistry, January 1998, Elsevier

    Daniel Metzger

  172. Spatio-temporally controlled site-specific somatic mutagenesis in the mouse

    Article • Proceedings of the National Academy of Sciences, December 1997, Proceedings of the National Academy of Sciences

    Daniel Metzger

  173. Specific and Redundant Functions of Retinoid X Receptor/Retinoic Acid Receptor Heterodimers in Differentiation, Proliferation, and Apoptosis of F9 Embryonal Carcinoma Cells

    Article • Journal of Cell Biology, November 1997, Rockefeller University Press

    Daniel Metzger

  174. SNF2beta-BRG1 is essential for the viability of F9 murine embryonal carcinoma cells.

    Article • Molecular and Cellular Biology, October 1997, ASM Journals

    Daniel Metzger

  175. Regulation of Cre Recombinase Activity by Mutated Estrogen Receptor Ligand-Binding Domains

    Article • Biochemical and Biophysical Research Communications, August 1997, Elsevier

    Daniel Metzger

  176. Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cells.

    Article • Molecular and Cellular Biology, June 1997, ASM Journals

    Daniel Metzger

  177. Ligand-activated site-specific recombination in mice.

    Article • Proceedings of the National Academy of Sciences, October 1996, Proceedings of the National Academy of Sciences

    Daniel Metzger

  178. Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

    Article • Science, December 1995, American Association for the Advancement of Science

    Daniel Metzger

  179. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase.

    Article • Proceedings of the National Academy of Sciences, July 1995, Proceedings of the National Academy of Sciences

    Daniel Metzger

  180. Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo

    Article • Molecular Endocrinology, May 1995, Endocrine Society

    Dr Simak Ali, Daniel Metzger

  181. Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

    Article • Journal of Biological Chemistry, April 1995, Elsevier

    Dr Simak Ali, Daniel Metzger

  182. Production and Characterization of Monoclonal Antibodies Recognising Defined Regions of the Human Oestrogen Receptor

    Article • Hybridoma, August 1993, Mary Ann Liebert Inc

    Dr Simak Ali, Daniel Metzger

  183. Mechanisms of antihormone action

    Article • The Journal of Steroid Biochemistry and Molecular Biology, March 1992, Elsevier

    Daniel Metzger

  184. Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast

    Article • Nucleic Acids Research, January 1992, Oxford University Press (OUP)

    Daniel Metzger

  185. The lack of transcriptional activation of the v-erbA oncogene is in part due to a mutation present in the DNA binding domain of the protein

    Article • Nucleic Acids Research, August 1990, Oxford University Press (OUP)

    Daniel Metzger

  186. The human oestrogen receptor functions in yeast

    Article • Nature, July 1988, Springer Science + Business Media

    Daniel Metzger

  187. Targeted Somatic Mutagenesis in the Mouse Epidermis

    Article • Springer Science + Business Media

    Daniel Metzger