Sander Houten

Metabolic crosstalk between organelles

• The FASEB Journal
• December 2018

News and views

• Journal of Inherited Metabolic Disease
• February 2018

Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice

• Gastroenterology
• January 2018

Changes in the Metabolome in Response to Low-Dose Exposure to Environmental Chemicals U...

• PLoS ONE
• July 2016

In vivomouse myocardial31P MRS using three-dimensional image-selectedin vivospectroscop...

• NMR in Biomedicine
• August 2015

Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine m...

• AJP Endocrinology and Metabolism
• August 2015

Corrigendum

• Experimental Biology and Medicine
• July 2015

Novel, Compound Heterozygous, Single-Nucleotide Variants inMARS2Associated with Develop...

• Human Mutation
• April 2015

Fiber-type-specific sensitivities and phenotypic adaptations to dietary fat overload di...

• The Journal of Nutritional Biochemistry
• February 2015

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insuli...

• Journal of Diabetes Research
• January 2015

High-protein diets prevent steatosis and induce hepatic accumulation of monomethyl bran...

• The Journal of Nutritional Biochemistry
• December 2014

Pioglitazone treatment restoresin vivomuscle oxidative capacity in a rat model of diabetes

• Diabetes Obesity and Metabolism
• October 2014

SUMOylation-Dependent LRH-1/PROX1 Interaction Promotes Atherosclerosis by Decreasing He...

• Cell Metabolism
• October 2014

Multilayered Genetic and Omics Dissection of Mitochondrial Activity in a Mouse Referenc...

• Cell
• September 2014

Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signalin...

• Hepatology
• August 2014

A Mitochondrial Expatriate: Nuclear Pyruvate Dehydrogenase

• Cell
• July 2014

Plasma acylcarnitines inadequately reflect tissue acylcarnitine metabolism

• Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
• July 2014

In vivo proton T1relaxation times of mouse myocardial metabolites at 9.4 T

• Magnetic Resonance in Medicine
• June 2014

Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductas...

• Human Molecular Genetics
• May 2014

Fasting Serum Taurine-Conjugated Bile Acids Are Elevated in Type 2 Diabetes and Do Not ...

• The Journal of Clinical Endocrinology & Metabolism
• April 2014

Optimizing anesthetic regimen for surgery in mice through minimization of hemodynamic, ...

• Experimental Biology and Medicine
• March 2014

Food withdrawal lowers energy expenditure and induces inactivity in long-chain fatty ac...

• The FASEB Journal
• March 2014

Aberrant protein acylation is a common observation in inborn errors of acyl-CoA metabolism

• Journal of Inherited Metabolic Disease
• February 2014

Mitochondrial protein acetylation is driven by acetyl-CoA from fatty acid oxidation

• Human Molecular Genetics
• February 2014

Identification and characterization of Eci3, a murine kidney-specific  3, 2-enoyl-CoA i...

• The FASEB Journal
• December 2013

Muscle MRI in patients with long-chain fatty acid oxidation disorders

• Journal of Inherited Metabolic Disease
• December 2013

ACAD9, a complex I assembly factor with a moonlighting function in fatty acid oxidation...

• Human Molecular Genetics
• October 2013

Myocardial energy shortage and unmet anaplerotic needs in the fasted long-chain acyl-Co...

• Cardiovascular Research
• September 2013

Peroxisomes contribute to the acylcarnitine production when the carnitine shuttle is de...

• Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
• September 2013

Biochemical Competition Makes Fatty-Acid β-Oxidation Vulnerable to Substrate Overload

• PLoS Computational Biology
• August 2013

Impaired amino acid metabolism contributes to fasting-induced hypoglycemia in fatty aci...

• Human Molecular Genetics
• August 2013

Substrate specificity of human carnitine acetyltransferase: Implications for fatty acid...

• Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
• June 2013

Prevention and reversal of hepatic steatosis with a high-protein diet in mice

• Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
• May 2013

Carnitine supplementation attenuates myocardial lipid accumulation in long-chain acyl-C...

• Journal of Inherited Metabolic Disease
• April 2013

Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intra...

• Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
• April 2013

Carnitine palmitoyltransferase 2 and carnitine/acylcarnitine translocase are involved i...

• The FASEB Journal
• January 2013

Genetic basis of hyperlysinemia

• Orphanet Journal of Rare Diseases
• January 2013

Acylcarnitines

• Diabetes
• December 2012

Adaptive reciprocity of lipid and glucose metabolism in human short-term starvation

• AJP Endocrinology and Metabolism
• December 2012

Bile Acid Binding Resin Improves Metabolic Control through the Induction of Energy Expe...

• PLoS ONE
• August 2012

Functional redundancy of mitochondrial enoyl-CoA isomerases in the oxidation of unsatur...

• The FASEB Journal
• July 2012

Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-...

• Metabolism
• July 2012

Improving the description of metabolic networks: the TCA cycle as example

• The FASEB Journal
• June 2012

Muscle or liver-specific Sirt3 deficiency induces hyperacetylation of mitochondrial pro...

• Scientific Reports
• May 2012

A Diet Rich in Unsaturated Fatty Acids Prevents Progression Toward Heart Failure in a R...

• Circulation Heart Failure
• May 2012

Peroxisomal L-bifunctional enzyme (Ehhadh) is essential for the production of medium-ch...

• Journal of Lipid Research
• April 2012

Bezafibrate lowers very long-chain fatty acids in X-linked adrenoleukodystrophy fibrobl...

• Journal of Inherited Metabolic Disease
• March 2012

Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pe...

• Metabolism
• January 2012

Role of Medium- and Short-Chain L-3-Hydroxyacyl-CoA Dehydrogenase in the Regulation of ...

• Endocrinology
• December 2011

New Driver for Lipid Synthesis

• Cell
• November 2011

The metabolic footprint of aging in mice

• Scientific Reports
• October 2011

Fasting-Induced Myocardial Lipid Accumulation in Long-Chain Acyl-CoA Dehydrogenase Knoc...

• Circulation Cardiovascular Imaging
• September 2011

Differential effects of short- and long-term high-fat diet feeding on hepatic fatty aci...

• Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
• July 2011

Lowering Bile Acid Pool Size with a Synthetic Farnesoid X Receptor (FXR) Agonist Induce...

• Journal of Biological Chemistry
• June 2011

Post-natal myogenic and adipogenic developmental

• Nucleus
• May 2011

PARP-2 Regulates SIRT1 Expression and Whole-Body Energy Expenditure

• Cell Metabolism
• April 2011

Critical assessment of human metabolic pathway databases: a stepping stone for future i...

• BMC Systems Biology
• January 2011

Acyl-CoA Dehydrogenase 9 Is Required for the Biogenesis of Oxidative Phosphorylation Co...

• Cell Metabolism
• September 2010

The Effects of Long- or Medium-Chain Fat Diets on Glucose Tolerance and Myocellular Con...

• Obesity
• July 2010

The enzymology of mitochondrial fatty acid beta-oxidation and its application to follow...

• Journal of Inherited Metabolic Disease
• May 2010

A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation

• Journal of Inherited Metabolic Disease
• March 2010

Effect of Statins on the Viability of Macrophages and Smooth Muscle Cells

• Journal of Cardiovascular Pharmacology
• March 2010

Glutamine Synthetase in Muscle Is Required for Glutamine Production during Fasting and ...

• Journal of Biological Chemistry
• January 2010

Increased mitochondrial content rescues in vivo muscle oxidative capacity in long-term ...

• The FASEB Journal
• December 2009

Mitochondrial long chain fatty acid β-oxidation in man and mouse

• Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
• August 2009

Serum Bile Acids Are Higher in Humans With Prior Gastric Bypass: Potential Contribution...

• Obesity
• April 2009

Muscle acylcarnitines during short-term fasting in lean healthy men

• Clinical Science
• April 2009

Effects of Insulin on Ketogenesis Following Fasting in Lean and Obese Men

• Obesity
• February 2009

Pyruvate dehydrogenase kinase 4 expression is synergistically induced by AMP-activated ...

• Cellular and Molecular Life Sciences
• February 2009

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Me...

• Cell Metabolism
• February 2009

A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis

• AJP Endocrinology and Metabolism
• January 2009

Metabolomics: Unraveling the chemical individuality of common human diseases

• Annals of Medicine
• January 2009

Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Me...

• Cell Metabolism
• November 2008

Increased intramyocellular lipid content but normal skeletal muscle mitochondrial oxida...

• The FASEB Journal
• July 2008

The Glucosylceramide Synthase InhibitorN-(5-Adamantane-1-yl-methoxy-pentyl)-deoxynojiri...

• Journal of Pharmacology and Experimental Therapeutics
• June 2008

A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporter...

• AJP Gastrointestinal and Liver Physiology
• May 2008

Characterization of l-aminocarnitine, an inhibitor of fatty acid oxidation

• Molecular Genetics and Metabolism
• April 2008

Peroxisome Proliferator-activated Receptor (PPAR)-2 Controls Adipocyte Differentiation ...

• Journal of Biological Chemistry
• October 2007

Compromised Intestinal Lipid Absorption in Mice with a Liver-Specific Deficiency of Liv...

• Molecular and Cellular Biology
• October 2007

In VivoImaging of Farnesoid X Receptor Activity Reveals the Ileum as the Primary Bile A...

• Molecular Endocrinology
• June 2007

A liver revival featuring bile acids

• Journal of Hepatology
• March 2007

The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice

• Genes & Development
• February 2007

Homing in on bile acid physiology

• Cell Metabolism
• December 2006

Peroxisomes and bile acid biosynthesis

• Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
• December 2006

Endocrine functions of bile acids

• The EMBO Journal
• March 2006

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

• Nature
• January 2006

Manipulation of isoprenoid biosynthesis as a possible therapeutic option in mevalonate ...

• Arthritis & Rheumatism
• January 2006

PGC-1α

• Cell
• October 2004

Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

• Journal of Clinical Investigation
• May 2004

Peroxisome proliferator-activated receptor-γ: too much of a good thing causes harm

• EMBO Reports
• February 2004

The enterohepatic nuclear receptors are major regulators of the enterohepatic circulati...

• Annals of Medicine
• January 2004

Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ ...

• Proceedings of the National Academy of Sciences
• November 2003

Carrier frequency of the V377I (1129G>A) MVK mutation, associated with Hyper-IgD and pe...

• European Journal of Human Genetics
• February 2003

Regulation of Isoprenoid/Cholesterol Biosynthesis in Cells from Mevalonate Kinase-defic...

• Journal of Biological Chemistry
• December 2002

Hyper IgD syndrome (HIDS) associated with in vitro evidence of defective monocyte TNFRS...

• Clinical & Experimental Immunology
• December 2002

Lack of isoprenoid products raises ex vivo interleukin-1? secretion in hyperimmunoglobu...

• Arthritis & Rheumatism
• October 2002

Erratum: Organization of the mevalonate kinase (MVK) gene and identification of novel m...

• European Journal of Human Genetics
• August 2001

Organization of the mevalonate kinase (MVK) gene and identification of novel mutations ...

• European Journal of Human Genetics
• April 2001

Nonorthologous Gene Displacement of Phosphomevalonate Kinase

• Molecular Genetics and Metabolism
• March 2001

Biochemical and genetic aspects of mevalonate kinase and its deficiency

• Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
• December 2000

• Journal of Inherited Metabolic Disease
• January 2000

• Journal of Inherited Metabolic Disease
• January 2000

Identification and Characterization of Three Novel Missense Mutations in Mevalonate Kin...

• Human Molecular Genetics
• August 1999

Mutations in MVK, encoding mevalonate kinase, cause hyperimmunoglobulinaemiaD and perio...

• Nature Genetics
• June 1999