All Stories

  1. A systematic review and network meta-analysis of randomised controlled trials comparing neoadjuvant treatment strategies for stage II and III rectal cancer

    Article • Critical Reviews in Oncology/Hematology, March 2023, Elsevier

    Constantinos Simillis

  2. Systematic review and meta-analysis comparing perioperative outcomes of emergency appendectomy performed by trainee vs trained surgeon

    Article • The American Journal of Surgery, January 2023, Elsevier

    Constantinos Simillis

  3. Operative blood loss adversely affects short and long-term outcomes after colorectal cancer surgery: results of a systematic review and meta-analysis

    Article • Techniques in Coloproctology, September 2022, Springer Science + Business Media

    Constantinos Simillis

  4. Locally Recurrent Rectal Cancer According to a Standardized MRI Classification System: A Systematic Review of the Literature

    Article • Journal of Clinical Medicine, June 2022, MDPI AG

    Constantinos Simillis

  5. Transanal tube versus defunctioning stoma after low anterior resection for rectal cancer: network meta-analysis of randomized controlled trials

    Article • BJS, May 2022, Oxford University Press (OUP)

    Constantinos Simillis

  6. Abdominal versus perineal approach for external rectal prolapse: systematic review with meta-analysis

    Article • BJS Open, March 2022, Oxford University Press (OUP)

    Constantinos Simillis

  7. A systematic review and network meta-analysis comparing energy devices used in colorectal surgery

    Article • Techniques in Coloproctology, February 2022, Springer Science + Business Media

    Constantinos Simillis

  8. Comment on: Prognostic importance of circumferential resection margin in the era of evolving surgical and multidisciplinary treatment of rectal cancer: a systematic review and meta-analysis

    Article • Surgery, November 2021, Elsevier

    Constantinos Simillis

  9. A systematic review of the literature assessing operative blood loss and postoperative outcomes after colorectal surgery

    Article • International Journal of Colorectal Disease, October 2021, Springer Science + Business Media

    Constantinos Simillis

  10. Reducing ileus after colorectal surgery: A network meta-analysis of therapeutic interventions

    Article • Clinical Nutrition, July 2021, Elsevier

    Constantinos Simillis

  11. Systematic review of classification systems for locally recurrent rectal cancer

    Article • BJS Open, May 2021, Oxford University Press (OUP)

    Constantinos Simillis

  12. Factors associated with metachronous metastases and survival in locally advanced and recurrent rectal cancer

    Article • BJS Open, August 2020, Oxford University Press (OUP)

    Constantinos Simillis

  13. The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review

    Article • Cell Communication and Signaling, April 2020, Springer Science + Business Media

    Constantinos Simillis

  14. Postoperative chemotherapy improves survival in patients with resected high‐risk Stage II colorectal cancer: results of a systematic review and meta‐analysis

    Article • Colorectal Disease, February 2020, Wiley

    Constantinos Simillis

  15. Anorectal Manometry Versus Patient-Reported Outcome Measures as a Predictor of Maximal Treatment for Fecal Incontinence

    Article • Annals of Coloproctology, December 2019, Korean Society of Coloproctology (KAMJE)

    Constantinos Simillis

  16. Generalised purulent peritonitis and small bowel obstruction due to a spontaneously perforated ovarian dermoid cyst

    Article • BMJ Case Reports, October 2019, BMJ

    Constantinos Simillis

  17. Comment on “Robotic Versus Laparoscopic Surgery for Rectal Cancer An Evidence-based Approach”

    Article • Annals of Surgery, August 2019, Wolters Kluwer Health

    Constantinos Simillis

  18. Open Versus Laparoscopic Versus Robotic Versus Transanal Mesorectal Excision for Rectal Cancer

    Article • Annals of Surgery, July 2019, Wolters Kluwer Health

    Constantinos Simillis

  19. A systematic review and network meta-analysis comparing treatments for faecal incontinence

    Article • International Journal of Surgery, June 2019, Elsevier

    Constantinos Simillis

  20. Generalised peritonitis from strangulated small bowel obstruction secondary to mesh erosion: a rare long-term complication of laparoscopic mesh sacrohysteropexy

    Article • BMJ Case Reports, May 2019, BMJ

    Constantinos Simillis

  21. Primary Tumor Resection in Patients with Incurable Localized or Metastatic Colorectal Cancer: A Systematic Review and Meta-analysis

    Article • Extremophiles, March 2019, Springer Science + Business Media

    Constantinos Simillis

  22. Suture choice to reduce occurrence of surgical site infection, hernia, wound dehiscence and sinus/fistula: a network meta-analysis

    Article • Annals of The Royal College of Surgeons of England, March 2019, Royal College of Surgeons of England

    Constantinos Simillis

  23. The obesity paradox in beyond total mesorectal excision surgery for locally advanced and recurrent rectal cancer

    Article • Updates in Surgery, February 2019, Springer Science + Business Media

    Constantinos Simillis

  24. A systematic review of the literature reporting on randomised controlled trials comparing treatments for faecal incontinence in adults

    Article • Acta Chirurgica Belgica, January 2019, Taylor & Francis

    Constantinos Simillis

  25. Robotic Versus Laparoscopic Surgery for Rectal Cancer

    Article • Annals of Surgery, December 2018, Wolters Kluwer Health

    Constantinos Simillis

  26. Ileal Pouch Salvage, Pouch Failure and Redo Surgery

    Article • November 2018, Springer Science + Business Media

    Constantinos Simillis

  27. A meta-analysis assessing the survival implications of subclassifying T3 rectal tumours

    Article • European Journal of Cancer, November 2018, Elsevier

    Constantinos Simillis

  28. A systematic review and meta-analysis comparing adverse events and functional outcomes of different pouch designs after restorative proctocolectomy

    Article • Colorectal Disease, April 2018, Wiley

    Constantinos Simillis

  29. Sacral nerve stimulation versus percutaneous tibial nerve stimulation for faecal incontinence: a systematic review and meta-analysis

    Article • International Journal of Colorectal Disease, February 2018, Springer Science + Business Media

    Constantinos Simillis

  30. Functional outcomes with handsewn versus stapled anastomoses in the treatment of ultralow rectal cancer

    Article • Updates in Surgery, January 2018, Springer Science + Business Media

    Constantinos Simillis

  31. Does a missed obstetric anal sphincter injury at time of delivery affect short-term functional outcome?

    Article • Annals of The Royal College of Surgeons of England, January 2018, Royal College of Surgeons of England

    Constantinos Simillis

  32. Small bowel obstruction secondary to mesh erosion - a rare long-term complication of laparoscopic mesh sacrohysteropexy

    Article • Medical Case Reports, January 2018, Scitechnol Biosoft Pvt. Ltd.

    Constantinos Simillis

  33. Diagnostic accuracy of anorectal manometry for fecal incontinence: a meta-analysis

    Article • Acta Chirurgica Belgica, November 2017, Taylor & Francis

    Constantinos Simillis

  34. The effect of adjuvant chemotherapy on survival and recurrence after curative rectal cancer surgery in patients who are histologically node negative after neoadjuvant chemoradiotherapy

    Article • Colorectal Disease, November 2017, Wiley

    Constantinos Simillis

  35. Magnetic resonance defecography versus clinical examination and fluoroscopy: a systematic review and meta-analysis

    Article • Techniques in Coloproctology, November 2017, Springer Science + Business Media

    Constantinos Simillis

  36. A systematic review of transabdominal levator division during abdominoperineal excision of the rectum (APER)

    Article • Techniques in Coloproctology, September 2017, Springer Science + Business Media

    Constantinos Simillis

  37. Social media and colorectal cancer: A systematic review of available resources

    Article • PLOS One, August 2017, PLOS

    Constantinos Simillis

  38. Colorectal cancer diagnosed during pregnancy

    Article • European Journal of Gastroenterology & Hepatology, July 2017, Wolters Kluwer Health

    Constantinos Simillis

  39. Discrepancies between NCCN and ESMO guidelines in the management of anal cancer: a qualitative review

    Article • Updates in Surgery, June 2017, Springer Science + Business Media

    Constantinos Simillis

  40. Functional and quality of life outcomes following obstetric anal sphincter injury (OASI): does the grade of injury affect outcomes?

    Article • International Urogynecology Journal, May 2017, Springer Science + Business Media

    Constantinos Simillis

  41. A comparative study of short-term outcomes of colorectal cancer surgery in the elderly population

    Article • Acta Chirurgica Belgica, May 2017, Taylor & Francis

    Constantinos Simillis

  42. A meta-analysis comparing the risk of metastases in patients with rectal cancer and MRI-detected extramural vascular invasion (mrEMVI) vs mrEMVI-negative cases

    Article • British Journal of Cancer, April 2017, Springer Science + Business Media

    Constantinos Simillis

  43. Acute appendicitis

    Article • BMJ, April 2017, BMJ

    Constantinos Simillis

  44. Evaluation of sexual dysfunction in female patients presenting with faecal incontinence or defecation disorder

    Article • International Journal of Colorectal Disease, March 2017, Springer Science + Business Media

    Constantinos Simillis

  45. A Systematic Review to Assess Resection Margin Status After Abdominoperineal Excision and Pelvic Exenteration for Rectal Cancer

    Article • Annals of Surgery, February 2017, Wolters Kluwer Health

    Constantinos Simillis

  46. ROLE OF BISPECTRAL INDEX AND SUPPRESSION RATIO MONITORING WITHIN THE EMERGENCY DEPARTMENT AFTER RETURN OF SPONTANEOUS CIRCULATION FOLLOWING CARDIAC ARREST?: A META-ANALYSIS

    Article • Emergency Medicine Journal, November 2016, BMJ

    Constantinos Simillis

  47. Methods to decrease blood loss during liver resection: a network meta-analysis

    Article • Cochrane Database of Systematic Reviews, October 2016, Wiley

    Constantinos Simillis

  48. A Systematic Review Assessing Medical Treatment for Rectovaginal and Enterovesical Fistulae in Crohn’s Disease

    Article • Journal of Clinical Gastroenterology, October 2016, Wolters Kluwer Health

    Constantinos Simillis

  49. A challenging gastrointestinal hemorrhage after gastric bypass treated with interventional radiology

    Article • Surgery for Obesity and Related Diseases, August 2016, Elsevier

    Constantinos Simillis

  50. A network meta-analysis comparing perioperative outcomes of interventions aiming to decrease ischemia reperfusion injury during elective liver resection

    Article • Surgery, April 2016, Elsevier

    Constantinos Simillis

  51. A systematic review of transanal total mesorectal excision: is this the future of rectal cancer surgery?

    Article • Colorectal Disease, January 2016, Wiley

    Constantinos Simillis

  52. A Cochrane systematic review and network meta-analysis comparing treatment strategies aiming to decrease blood loss during liver resection

    Article • International Journal of Surgery, November 2015, Elsevier

    Constantinos Simillis

  53. Systematic review and network meta-analysis comparing clinical outcomes and effectiveness of surgical treatments for haemorrhoids

    Article • BJS, September 2015, Wiley

    Constantinos Simillis

  54. Maternal and neonatal outcomes in women undergoing bariatric surgery: a systematic review and meta-analysis

    Article • European Journal of Obstetrics & Gynecology and Reproductive Biology, October 2014, Elsevier

    Constantinos Simillis

  55. Methods to decrease blood loss during liver resection: a network meta-analysis

    Article • April 2014, Wiley

    Constantinos Simillis

  56. Intraoperative rectal washout in rectal cancer surgery: A survey of current practice in the UK

    Article • International Journal of Surgery, November 2013, Elsevier

    Constantinos Simillis

  57. A very challenging leak from a sleeve gastrectomy

    Article • Surgery for Obesity and Related Diseases, July 2013, Elsevier

    Constantinos Simillis

  58. Management of the Hepatic Lymph Nodes During Resection of Liver Metastases from Colorectal Cancer: A Systematic Review

    Article • Current Colorectal Cancer Reports, March 2013, Springer Science + Business Media

    Constantinos Simillis

  59. A meta-analysis comparing simultaneous versus delayed resections in patients with synchronous colorectal liver metastases

    Article • Surgical Oncology, March 2013, Elsevier

    Constantinos Simillis

  60. 14. A meta-analysis, comparing simultaneous versus delayed resections in patients with synchronous colorectal liver metastases

    Article • European Journal of Surgical Oncology, November 2012, Elsevier

    Constantinos Simillis

  61. Identification of Two Mutations (F758W and F758Y) in the N-methyl-D-aspartate Receptor Glycine-binding Site that Selectively Prevent Competitive Inhibition by Xenon without Affecting Glycine Binding

    Article • Anesthesiology, July 2012, Wolters Kluwer Health

    Constantinos Simillis

  62. Designer stoma care

    Article • Colorectal Disease, July 2011, Wiley

    Constantinos Simillis

  63. A meta-analysis comparing conservative treatment versus acute appendectomy for complicated appendicitis (abscess or phlegmon)

    Article • Surgery, June 2010, Elsevier

    Constantinos Simillis

  64. Do we need to change the legislation to a system of presumed consent to address organ shortage?

    Article • Medicine Science and the Law, April 2010, SAGE Publications

    Constantinos Simillis

  65. Meta-analysis of the Role of Granulomas in the Recurrence of Crohn Disease

    Article • Diseases of the Colon & Rectum, February 2010, Wolters Kluwer Health

    Constantinos Simillis

  66. A systematic review of early versus delayed treatment for type III supracondylar humeral fractures in children

    Article • Injury, March 2009, Elsevier

    Constantinos Simillis

  67. The Risk of Oral Contraceptives in the Etiology of Inflammatory Bowel Disease: A Meta-Analysis

    Article • The American Journal of Gastroenterology, September 2008, Wolters Kluwer Health

    Constantinos Simillis

  68. Euthanasia: a summary of the law in England and Wales

    Article • Medicine Science and the Law, July 2008, SAGE Publications

    Constantinos Simillis

  69. A Meta-Analysis Comparing Incidence of Recurrence and Indication for Reoperation After Surgery for Perforating Versus Nonperforating Crohn's Disease

    Article • The American Journal of Gastroenterology, January 2008, Wolters Kluwer Health

    Constantinos Simillis

  70. Competitive Inhibition at the Glycine Site of the N-Methyl-d-aspartate Receptor by the Anesthetics Xenon and Isoflurane

    Article • Anesthesiology, November 2007, Wolters Kluwer Health

    Constantinos Simillis

  71. A Meta-Analysis Comparing Conventional End-to-End Anastomosis vs. Other Anastomotic Configurations After Resection in Crohnʼs Disease

    Article • Diseases of the Colon & Rectum, October 2007, Wolters Kluwer Health

    Constantinos Simillis

  72. Laparoscopic versus open hepatic resections for benign and malignant neoplasms—a meta-analysis

    Article • Surgery, February 2007, Elsevier

    Constantinos Simillis

  73. Diagnostic Precision of Anti-Saccharomyces cerevisiae Antibodies and Perinuclear Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Disease

    Article • The American Journal of Gastroenterology, October 2006, Wolters Kluwer Health

    Constantinos Simillis