All Stories

  1. Endosymbiotic algal photosynthesis shapes diel transcriptome architecture in its ciliate host Paramecium bursaria

    Article • April 2026, openRxiv

    Chuan Ku

  2. Mitochondrial genome reduction and accelerated evolution in planktonic foraminiferans

    Article • September 2025, Cold Spring Harbor Laboratory Press

    Chuan Ku

  3. An interbacterial cysteine protease toxin inhibits cell growth by targeting type II DNA topoisomerases GyrB and ParE

    Article • PLoS Biology, May 2025, PLOS

    Chuan Ku

  4. Cathepsin X is a conserved cell death protein involved in algal response to environmental stress

    Article • Current Biology, May 2025, Elsevier

    Chuan Ku

  5. Host-Calibrated Time Tree Caps the Age of Giant Viruses

    Article • Molecular Biology and Evolution, February 2025, Oxford University Press (OUP)

    Chuan Ku

  6. An Interbacterial Cysteine Protease Toxin Inhibits Cell Growth by Targeting Type II DNA Topoisomerases GyrB and ParE

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Chuan Ku

  7. Host-calibrated time tree caps the age of giant viruses

    Article • September 2024, Springer Science + Business Media

    Chuan Ku

  8. Haplotype-aware multiomics unveils the regulatory basis of haplodiplontic life-cycle differentiation in a cosmopolitan marine alga

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Chuan Ku

  9. Cathepsin X is a conserved cell death protein involved in algal response to environmental stress

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Chuan Ku

  10. Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics

    Article • Science Advances, October 2023, American Association for the Advancement of Science

    Chuan Ku

  11. Widespread Distribution and Evolution of Poxviral Entry-Fusion Complex Proteins in Giant Viruses

    Article • Microbiology Spectrum, March 2023, ASM Journals

    Chuan Ku, Dr Wen Chang

  12. Widespread distribution and evolution of poxviral entry-fusion complex proteins in giant viruses

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Chuan Ku, Dr Wen Chang

  13. Single-cell transcriptomics unveils xylem cell development and evolution

    Article • January 2023, Springer Science + Business Media

    Chuan Ku

  14. Complete Genome Sequence of Phaeobacter sp. Strain G2, Isolated from a Lab Culture of the Calcifying Alga Emiliania huxleyi

    Article • Microbiology Resource Announcements, November 2022, ASM Journals

    Chuan Ku

  15. Daily turnover of active giant virus infection during algal blooms revealed by single-cell transcriptomics

    Article • October 2022, Cold Spring Harbor Laboratory Press

    Chuan Ku

  16. Complex evolution and inheritance in marine algae

    Article • New Phytologist, May 2022, Wiley

    Chuan Ku

  17. Single-cell transcriptomics unveils xylem cell development and evolution

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Chuan Ku

  18. Unraveling Gene Content Variation Across Eukaryotic Giant Viruses Based on Network Analyses and Host Associations

    Article • Virus Evolution, September 2021, Oxford University Press (OUP)

    Chuan Ku

  19. Giant Virus-Eukaryote Interactions as Ecological and Evolutionary Driving Forces

    Article • mSystems, August 2021, ASM Journals

    Chuan Ku

  20. Host Range and Coding Potential of Eukaryotic Giant Viruses

    Article • Viruses, November 2020, MDPI AG

    Chuan Ku

  21. A single-cell view on alga-virus interactions reveals sequential transcriptional programs and infection states

    Article • Science Advances, May 2020, American Association for the Advancement of Science

    Chuan Ku

  22. Did giant and large dsDNA viruses originate before their eukaryotic hosts?

    Article • Proceedings of the National Academy of Sciences, January 2020, Proceedings of the National Academy of Sciences

    Chuan Ku

  23. Using single-cell transcriptomics to understand functional states and interactions in microbial eukaryotes

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, October 2019, Royal Society Publishing

    Chuan Ku

  24. Tracking infection dynamics at single-cell level reveals highly resolved expression programs of a large virus infecting algal blooms

    Article • September 2019, Cold Spring Harbor Laboratory Press

    Chuan Ku

  25. Complete Genome Sequence of Sulfitobacter sp. Strain D7, a Virulent Bacterium Isolated from an Emiliania huxleyi Algal Bloom in the North Atlantic

    Article • Microbiology Resource Announcements, November 2018, ASM Journals

    Chuan Ku

  26. Bacterial virulence against an oceanic bloom-forming phytoplankter is mediated by algal DMSP

    Article • Science Advances, October 2018, American Association for the Advancement of Science

    Chuan Ku

  27. Late Mitochondrial Origin Is an Artifact

    Article • Genome Biology and Evolution, February 2017, Oxford University Press (OUP)

    Chuan Ku

  28. A natural barrier to lateral gene transfer from prokaryotes to eukaryotes revealed from genomes: the 70 % rule

    Article • BMC Biology, October 2016, Springer Science + Business Media

    Chuan Ku

  29. Endosymbiotic origin and differential loss of eukaryotic genes

    Article • Nature, August 2015, Nature

    Professor James McInerney, Chuan Ku

  30. Endosymbiotic gene transfer from prokaryotic pangenomes: Inherited chimerism in eukaryotes

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    Chuan Ku

  31. Endosymbiotic theory for organelle origins

    Article • Current Opinion in Microbiology, December 2014, Elsevier

    Dr Sven B Gould, Chuan Ku

  32. Molecular evolution of the actin-like MreB protein gene family in wall-less bacteria

    Article • Biochemical and Biophysical Research Communications, April 2014, Elsevier

    Dr Chih-Horng Kuo, Chuan Ku

  33. Molecular Evolution of the Substrate Utilization Strategies and Putative Virulence Factors in Mosquito-Associated Spiroplasma Species

    Article • Genome Biology and Evolution, February 2014, Oxford University Press (OUP)

    Dr Chih-Horng Kuo, Chuan Ku

  34. Complete Genome Sequence of Spiroplasma apis B31T (ATCC 33834), a Bacterium Associated with May Disease of Honeybees (Apis mellifera)

    Article • Genome Announcements, January 2014, ASM Journals

    Dr Chih-Horng Kuo, Chuan Ku

  35. Phylogenetic and Cophylogenetic Analyses of the Leaf-Nodule Symbiosis in Ardisia Subgenus Crispardisia (Myrsinaceae): Evidence from Nuclear and Chloroplast Markers and Bacterial rrn Operons

    Article • International Journal of Plant Sciences, January 2014, University of Chicago Press

    Chuan Ku

  36. Plastid origin: who, when and why?

    Article • Acta Societatis Botanicorum Poloniae, January 2014, Polish Botanical Society

    Chuan Ku

  37. Horizontal transfer of potential mobile units in phytoplasmas

    Article • Mobile Genetic Elements, September 2013, Taylor & Francis

    Dr Chih-Horng Kuo, Chuan Ku

  38. Comparison of Metabolic Capacities and Inference of Gene Content Evolution in Mosquito-Associated Spiroplasma diminutum and S. taiwanense

    Article • Genome Biology and Evolution, July 2013, Oxford University Press (OUP)

    Dr Chih-Horng Kuo, Chuan Ku

  39. The Complete Plastid Genome Sequence of Madagascar Periwinkle Catharanthus roseus (L.) G. Don: Plastid Genome Evolution, Molecular Marker Identification, and Phylogenetic Implications in Asterids

    Article • PLOS One, June 2013, PLOS

    Dr Chih-Horng Kuo, Chuan Ku

  40. Complete Genomes of Two Dipteran-Associated Spiroplasmas Provided Insights into the Origin, Dynamics, and Impacts of Viral Invasion in Spiroplasma

    Article • Genome Biology and Evolution, May 2013, Oxford University Press (OUP)

    Dr Chih-Horng Kuo, Chuan Ku

  41. Complete Plastid Genome Sequence of the Basal Asterid Ardisia polysticta Miq. and Comparative Analyses of Asterid Plastid Genomes

    Article • PLOS One, April 2013, PLOS

    Dr Chih-Horng Kuo, Chuan Ku