All Stories

  1. Dopaminergic changes in the subgenual cingulate cortex in dementia with lewy bodies associates with presence of depression
  2. Altered ceramide metabolism is a feature in the extracellular vesicle-mediated spread of alpha-synuclein in Lewy body disorders
  3. RT-QuIC Using C-Terminally Truncated α-Synuclein Forms Detects Differences in Seeding Propensity of Different Brain Regions from Synucleinopathies
  4. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
  5. Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein
  6. C9orf72 , age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts
  7. Prospective longitudinal evaluation of cytokines in mild cognitive impairment due to AD and Lewy body disease
  8. Neuropathological and biochemical investigation of Hereditary Ferritinopathy cases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress
  9. Label‐Free Nanoimaging of Neuromelanin in the Brain by Soft X‐ray Spectromicroscopy
  10. Label‐Free Nanoimaging of Neuromelanin in the Brain by Soft X‐ray Spectromicroscopy
  11. Investigating the presence of doubly phosphorylated α‐synuclein at tyrosine 125 and serine 129 in idiopathic Lewy body diseases
  12. Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia
  13. Trichloroethylene and its metabolite TaClo lead to degeneration of substantia nigra dopaminergic neurones: Effects in wild type and human A30P mutant α-synuclein mice
  14. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy
  15. Assessment of APOE in atypical parkinsonism syndromes
  16. MAPT p.V363I mutation
  17. A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity
  18. Neuropathological Changes in Dementia With Lewy Bodies and the Cingulate Island Sign
  19. Inflammation in mild cognitive impairment due to Parkinson's disease, Lewy body disease, and Alzheimer's disease
  20. Degeneration of dopaminergic circuitry influences depressive symptoms in Lewy body disorders
  21. Heterogeneity in α-synuclein subtypes and their expression in cortical brain tissue lysates from Lewy body diseases and Alzheimer's disease
  22. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia
  23. LRP10 in α-synucleinopathies
  24. Somatic variants in autosomal dominant genes are a rare cause of sporadic Alzheimer's disease
  25. High prevalence of focal and multi-focal somatic genetic variants in the human brain
  26. Frequency and signature of somatic variants in 1461 human brain exomes
  27. The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target
  28. The impact of stapling technique and surgeon specialism on anastomotic failure after right-sided colorectal resection: an international multicentre, prospective audit
  29. CXCR4 involvement in neurodegenerative diseases
  30. Mitochondrial dysfunction within the synapses of substantia nigra neurons in Parkinson’s disease
  31. Molecular changes in the absence of severe pathology in the pulvinar in dementia with Lewy bodies
  32. Oligogenic genetic variation of neurodegenerative disease genes in 980 postmortem human brains
  33. Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
  34. Gene expression analysis reveals chronic low level exposure to the pesticide diazinon affects psychological disorders gene sets in the adult rat
  35. Peripheral inflammation in prodromal Alzheimer’s and Lewy body dementias
  36. Mitochondrial DNA changes in pedunculopontine cholinergic neurons in Parkinson disease
  37. Regional levels of physiological α-synuclein are directly associated with Lewy body pathology
  38. Risk factors for unfavourable postoperative outcome in patients with Crohn's disease undergoing right hemicolectomy or ileocaecal resection An international audit by ESCP and S-ECCO
  39. SIRT1 ameliorates oxidative stress induced neural cell death and is down-regulated in Parkinson’s disease
  40. Neuronal Loss and Α-Synuclein Pathology in the Superior Colliculus and Its Relationship to Visual Hallucinations in Dementia with Lewy Bodies
  41. The relationship between method of anastomosis and anastomotic failure after right hemicolectomy and ileo-caecal resection: an international snapshot audit
  42. Trichloroethylene-induced formic aciduria in the male C57 Bl/6 mouse
  43. Erratum to: Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains
  44. Mitochondrial DNA point mutations and relative copy number in 1363 disease and control human brains
  45. Specific patterns of neuronal loss in the pulvinar nucleus in dementia with lewy bodies
  46. Sirtuin-2 Protects Neural Cells from Oxidative Stress and Is Elevated in Neurodegeneration
  47. Genetic compendium of 1511 human brains available through the UK Medical Research Council Brain Banks Network Resource
  48. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
  49. Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK
  50. Anatomic Connections of the Subgenual Cingulate Region
  51. Analysis of primary visual cortex in dementia with Lewy bodies indicates GABAergic involvement associated with recurrent complex visual hallucinations
  52. Telomerase Activity is Downregulated Early During Human Brain Development
  53. Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease
  54. A Low Mortality, High Morbidity Reduced Intensity Status Epilepticus (RISE) Model of Epilepsy and Epileptogenesis in the Rat
  55. Mechanism for the acute effects of organophosphate pesticides on the adult 5-HT system
  56. Exome sequencing in dementia with Lewy bodies
  57. Mitochondrial DNA Depletion in Respiratory Chain-Deficient Parkinson Disease Neurons
  58. Low-level repeated exposure to diazinon and chlorpyrifos decrease anxiety-like behaviour in adult male rats as assessed by marble burying behaviour
  59. Voxel-based analysis in neuroferritinopathy expands the phenotype and determines radiological correlates of disease severity
  60. Erratum to: Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria
  61. Changes to the lateral geniculate nucleus in Alzheimer's disease but not dementia with Lewy bodies
  62. Neural Differentiation Modulates the Vertebrate Brain Specific Splicing Program
  63. Selective loss of glucocerebrosidase activity in sporadic Parkinson’s disease and dementia with Lewy bodies
  64. Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria
  65. Rapid and equivalent systemic bioavailability of the antidotes HI-6 and dicobalt edetate via the intraosseous and intravenous routes
  66. Frontotemporal dementia and its subtypes: a genome-wide association study
  67. Intralobar fibres of the occipital lobe: A post mortem dissection study
  68. Pyroglutamylated amyloid-β is associated with hyperphosphorylated tau and severity of Alzheimer’s disease
  69. White matter connections of the supplementary motor area in humans
  70. Mitochondrial Abnormality Associates with Type-Specific Neuronal Loss and Cell Morphology Changes in the Pedunculopontine Nucleus in Parkinson Disease
  71. Variation in tau isoform expression in different brain regions and disease states
  72. A Multicenter Study of Glucocerebrosidase Mutations in Dementia With Lewy Bodies
  73. Neuroferritinopathy
  74. Sex differences in effects of low level domoic acid exposure
  75. British Journal of Neurosurgery
  76. Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease
  77. Real-time monitoring of superoxide generation and cytotoxicity in neuroblastoma mitochondria induced by 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline
  78. FUS and TDP43 genetic variability in FTD and CBS
  79. Relationship Between Mitochondria and α-Synuclein
  80. Transferrin and HFE genes interact in Alzheimer's disease risk: the Epistasis Project
  81. Synaptic Protein Alterations in Parkinson’s Disease
  82. Cellular pathology within the anterior cingulate cortex of patients with late-life depression: A morphometric study
  83. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
  84. Expression analysis of dopaminergic neurons in Parkinson’s disease and aging links transcriptional dysregulation of energy metabolism to cell death
  85. Any old iron?
  86. NOS3 gene rs1799983 polymorphism and incident dementia in elderly stroke survivors
  87. Morphometric Analysis of Neuronal and Glial Cell Pathology in the Caudate Nucleus in Late-Life Depression
  88. Examination of glucose transporter-1, transforming growth factor-β and neuroglobin immunoreactivity in the orbitofrontal cortex in late-life depression
  89. Mitochondrial Dysfunction in Parkinson's Disease
  90. Neuromelanin, neurotransmitter status and brainstem location determine the differential vulnerability of catecholaminergic neurons to mitochondrial DNA deletions
  91. The immunhistochemical examination of GABAergic interneuron markers in the dorsolateral prefrontal cortex of patients with late-life depression
  92. A morphometric examination of neuronal and glial cell pathology in the orbitofrontal cortex in late-life depression
  93. cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases
  94. Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene
  95. The low abundance of clonally expanded mitochondrial DNA point mutations in aged substantia nigra neurons
  96. Morphometric analysis of neuronal and glial cell pathology in the dorsolateral prefrontal cortex in late-life depression
  97. BuChE-K and APOE ϵ4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline
  98. Nature of Mitochondrial DNA Deletions in Substantia Nigra Neurons
  99. Decreased Fractalkine and Increased IP-10 Expression in Aged Brain of APPswe Transgenic Mice
  100. Common genetic variation within the Low-Density Lipoprotein Receptor-Related Protein 6 and late-onset Alzheimer's disease
  101. Individual dopaminergic neurons show raised iron levels in Parkinson disease
  102. The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts
  103. Hereditary multi-infarct dementia of the Swedish type is a novel disorder different from NOTCH3 causing CADASIL
  104. Soluble cell adhesion molecules in late-life depression
  105. Preliminary observation of elevated levels of nanocrystalline iron oxide in the basal ganglia of neuroferritinopathy patients
  106. Apolipoprotein  3 allele is associated with persistent hepatitis C virus infection
  107. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
  108. Quantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia
  109. Does the mitochondrial genome play a role in the etiology of Alzheimer’s disease?
  110. A Scan of Chromosome 10 Identifies a Novel Locus Showing Strong Association with Late-Onset Alzheimer Disease
  111. Genetic Variability in CHMP2B and Frontotemporal Dementia
  112. Looking for biogenic magnetite in brain ferritin using NMR relaxometry
  113. Comparative proteomic analysis using samples obtained with laser microdissection and saturation dye labelling
  114. Impact of Hypertension and Apolipoprotein E4 on Poststroke Cognition in Subjects >75 Years of Age
  115. The H1c haplotype at the MAPT locus is associated with Alzheimer's disease
  116. Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme
  117. Angiotensin converting enzyme insertion/deletion polymorphisms in vasovagal syncope
  118. Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration
  119. Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation
  120. Screening of the regulatory and coding regions of vascular endothelial growth factor in amyotrophic lateral sclerosis
  121. Ubiquilin 1 polymorphisms are not associated with late-onset Alzheimer's disease
  122. APOA1 polymorphism influences risk for early-onset nonfamiliar AD
  123. Familial neurocardiogenic (vasovagal) syncope
  124. Increase in Interleukin-1β in Late-Life Depression
  125. The K Variant of the Butyrylcholinesterase Gene Is Associated with Reduced Phosphorylation of Tau in Dementia Patients
  126. Correction: no evidence of an association between the T16189C mtDNA variant and late onset dementia (Gibson et al)
  127. High throughput approaches in neuroscience
  128. APOE  4 and cognitive decline in older stroke patients with early cognitive impairment
  129. Dementia with Lewy bodies: no association of polymorphisms in the human synphilin gene
  130. SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies
  131. Influence of the amyloid precursor protein locus on dementia in Down syndrome
  132. Functional genomics and proteomics: application in neurosciences
  133. Novel presenilin 1 mutation with profound neurofibrillary pathology in an indigenous Southern African family with early-onset Alzheimer's disease
  134. Polymorphism in the human DJ-1 gene is not associated with sporadic dementia with Lewy bodies or Parkinson's disease
  135. Chronic glial activation, neurodegeneration, and APP immunoreactive deposits following acute administration of double-stranded RNA
  136. Cognitive Decline in Down Syndrome—Reply
  137. Regulation of attention and response to therapy in dementia by butyrylcholinesterase
  138. Cholinesterase inhibitors in the treatment of dementia
  139. Dementia with Lewy bodies
  140. Neuroferritinopathy: A Window on the Role of Iron in Neurodegeneration
  141. The tau locus is not significantly associated with pathologically confirmed sporadic Parkinson's disease
  142. Selective Nicotinic Receptor Consequences in APPSWE Transgenic Mice
  143. Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice
  144. Clinical and Neuropathological Correlates of Apolipoprotein E Genotype in Dementia with Lewy Bodies
  145. Transferrin gene polymorphism in Alzheimer's disease and dementia with Lewy bodies in humans
  146. Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease
  147. No pathogenic mutations in the synphilin-1 gene in Parkinson's disease
  148. Nitric oxide synthase gene polymorphisms in Alzheimer's disease and dementia with Lewy bodies
  149. Is apolipoprotein e4 associated with cognitive decline in depression?
  150. Parkinson's disease is not associated with the combined ?-synuclein/apolipoprotein E susceptibility genotype
  151. The progression of cognitive impairment in dementia with Lewy bodies, vascular dementia and Alzheimer's disease
  152. Neuritogenic-Neurotoxic Effects of Membrane-Associated Forms ofAmyloid Precursor Prot ein
  153. Brain matrix metalloproteinase 1 levels are elevated in Alzheimer's disease
  154. Mitochondrial DNA haplogroups and susceptibility to AD and dementia with Lewy bodies
  155. Non-Alzheimer dementias
  156. Brain oestradiol and testosterone levels in Alzheimer's disease
  157. Distribution of Amyloid beta42 in Relation to the Cerebral Microvasculature in an Elderly Cohort with Alzheimer's Disease
  158. Hereditary Vascular Dementia Linked to Notch 3 Mutations: CADASIL in British Families
  159. The CCTTT polymorphism in the NOS2A gene is associated with dementia with Lewy bodies
  160. Risk for Alzheimer's disease in older late-onset cases is associated with HLA-DRB1*03
  161. Aberrant Splicing in the Presenilin-1 Intron 4 Mutation Causes Presenile Alzheimer's Disease by Increased A 42 Secretion
  162. Apolipoprotein E ϵ4 Allele, Temporal Lobe Atrophy, and White Matter Lesions in Late-Life Dementias
  163. α2-Macroglobulin polymorphisms in Alzheimerʼs disease and dementia with Lewy bodies
  164. Frequency of HLA-A and B alleles in early and late-onset Alzheimer's disease
  165. Diagnosis of Mitochondrial Disease: Assessment of Mitochondrial DNA Heteroplasmy in Blood
  166. LRP gene and late-onset Alzheimer's disease
  167. Butyrylcholinesterase K: an association with dementia with Lewy bodies
  168. Dopamine and nicotinic receptor binding and the levels of dopamine and homovanillic acid in human brain related to tobacco use
  169. Neuroblastoma and Alzheimer’s Disease Brain Cells Contain Aromatase Activity
  170. No association between the K variant of the butyrylcholinesterase gene and pathologically confirmed Alzheimer's disease
  171. Lack of association between the dopamine D2 receptor gene allele DRD2*A1 and cigarette smoking in a United Kingdom population
  172. Apolipoprotein E and alpha-1 antichymotrypsin polymorphism genotyping in Alzheimer's disease and in dementia with Lewy bodies Distinctions between diseases
  173. D2 dopamine receptor gene (DRD2) Taql A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele
  174. No association between a polymorphism in the presenilin 1 gene and dementia with Lewy bodies
  175. No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer's disease
  176. Presenilin polymorphisms in Alzheimer's disease
  177. HLA-DR antigens associated with major genetic risk for late-onset Alzheimerʼs disease
  178. Effect of aluminium on expression and processing of amyloid precursor protein
  179. Apolipoprotein E genotyping in Alzheimer's disease
  180. Apolipoprotein E Genotype and Alzheimer's Disease in an Elderly Norwegian Cohort
  181. Effect of apolipoprotein E genotype on Alzheimer's disease neuropathology in a cohort of elderly Norwegians
  182. Effects of Apolipoprotein E Genotype on Cortical Neuropathology in Senile Dementia of the Lewy Body and Alzheimer's Disease
  183. The role of the cholinergic system in the development of the human cerebellum
  184. Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: Possible index of early neuropathology
  185. Distribution of Nicotinic Receptors in the Human Hippocampus and Thalamus
  186. Transferrin receptors in the Parkinsonian midbrain
  187. Transferrin receptors in the normal human hippocampus and in Alzheimer's disease
  188. Protective effect of apoE ∈2 in Alzheimer's disease
  189. Distribution of neuronal nicotinic receptor subunits in human brain
  190. Apolipoprotein E genes in Lewy body and Parkinson's disease
  191. Autoradiographic comparison of cholinergic and other transmitter receptors in the normal human hippocampus
  192. Iron uptake in the brain of the myelin-deficient rat
  193. Cholinergic Transmitter and Neurotrophic Activities in Lewy Body Dementia
  194. Evidence for the localization of haemopexin immunoreactivity in neurones in the human brain
  195. Hippocampal p75 Nerve Growth Factor Receptor Immunoreactivity in Development, Normal Aging and Senescence
  196. Iron and aluminium in relation to brain ferritin in normal individuals and Alzheimer's-disease and chronic renal-dialysis patients
  197. Distribution of transferrin receptors in relation to cytochrome oxidase activity in the human spinal cord, lower brainstem and cerebellum
  198. Brain iron homeostasis
  199. Hippocampal nerve growth factor receptor immunoreactivity in patients with Alzheimer's and Parkinson's disease
  200. Uptake and Distribution of Iron and Transferrin in the Adult Rat Brain
  201. Immunocytochemical Localisation of Transferrin in the Human Brain
  202. Nerve Growth Factor Receptor-like Immunoreactivity in the Human Spinal Cord
  203. The imaging and quantification of aluminium in the human brain using dynamic secondary ion mass spectrometry (SIMS)
  204. Cortical serotonin-S2 receptor binding in Lewy body dementia, Alzheimer's and Parkinson's diseases
  205. Transferrin-gallium binding in Alzheimer's disease
  206. Laterality and 5HT2 receptors in human brain
  207. Distribution of nerve growth factor receptor immunoreactivity in the human hippocampus
  208. Brain transferrin receptors and the distribution of cytochrome oxidase
  209. Gallium-67 as a Potential Marker for Aluminium Transport in Rat Brain: Implications for Alzheimer's Disease
  210. Gallium-transferrin binding in Alzheimer disease
  211. Comparison of the regional distribution of transferrin receptors and aluminium in the forebrain of chronic renal dialysis patients
  212. Comparison of the regional distribution of transferrin receptors and aluminium in the forebrain of chronic renal dialysis patients
  213. Interaction between metal ions and neuroleptics