All Stories

  1. Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses
  2. OrthoXML-Tools: A Toolkit for Manipulating OrthoXML Files for Orthology Data
  3. EdgeHOG: a method for fine-grained ancestral gene order inference at large scale
  4. Unveiling the functional fate of duplicated genes through expression profiling and structural analysis
  5. Invest in data resources to make FAIR a reality
  6. Annotation matters: the effect of structural gene annotation on orthology inference
  7. Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs
  8. Orthology inference at scale with FastOMA
  9. OMAnnotator: a novel approach to building an annotated consensus genome sequence
  10. Reconstructing the last common ancestor of all eukaryotes
  11. When less is more: sketching with minimizers in genomics
  12. Quest for Orthologs in the Era of Biodiversity Genomics
  13. New developments for the Quest for Orthologs benchmark service
  14. EdgeHOG: fine-grained ancestral gene order inference at tree-of-life scale
  15. Matreex: Compact and Interactive Visualization for Scalable Studies of Large Gene Families
  16. Frequent jumps from human hosts
  17. AI and the democratization of knowledge
  18. Quality assessment of gene repertoire annotations with OMArk
  19. Orthology inference at scale with FastOMA
  20. DrosOMA: the Drosophila Orthologous Matrix browser
  21. OMA orthology in 2024: improved prokaryote coverage, ancestral and extant GO enrichment, a revamped synteny viewer and more in the OMA Ecosystem
  22. The SIB Swiss Institute of Bioinformatics Semantic Web of data
  23. Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses
  24. Exploring Disease Model Mouse Using Knowledge Graphs: Combining Gene Expression, Orthology, and Disease Datasets
  25. Protein length distribution is remarkably uniform across the tree of life
  26. Phylogenetic profiling in eukaryotes comes of age
  27. Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree
  28. Protein S-acylation controls the subcellular localization and biological activity of PHYTOCHROME KINASE SUBSTRATE
  29. Matreex: compact and interactive visualisation for scalable studies of large gene families
  30. Bringing science to the public in the light of evolution
  31. Multifaceted quality assessment of gene repertoire annotation with OMArk
  32. Reconstructing protein interactions across time using phylogeny-aware graph neural networks
  33. Bio-SODA UX: enabling natural language question answering over knowledge graphs with user disambiguation
  34. Control of PHYTOCHROME KINASE SUBSTRATE subcellular localization and biological activity by protein S-acylation
  35. Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
  36. ISMB 2022 proceedings
  37. The Quest for Orthologs orthology benchmark service in 2022
  38. Read2Tree: scalable and accurate phylogenetic trees from raw reads
  39. A Linear Time Solution to the Labeled Robinson–Foulds Distance Problem
  40. OMAMO: orthology-based alternative model organism selection
  41. How to build phylogenetic species trees with OMA
  42. Citrullination Was Introduced into Animals by Horizontal Gene Transfer from Cyanobacteria
  43. Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
  44. Bio-SODA: Enabling Natural Language Question Answering over Knowledge Graphs without Training Data
  45. ISMB/ECCB 2021 proceedings
  46. Homoeolog Inference Methods Requiring Bidirectional Best Hits or Synteny Miss Many Pairs
  47. Ten Years of Collaborative Progress in the Quest for Orthologs
  48. OMAmer: tree-driven and alignment-free protein assignment to subfamilies outperforms closest sequence approaches
  49. Want to track pandemic variants faster? Fix the bioinformatics bottleneck
  50. Gene Duplication and Gain in the Trematode Atriophallophorus winterbourni Contributes to Adaptation to Parasitism
  51. A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor
  52. NGS-Based S. aureus Typing and Outbreak Analysis in Clinical Microbiology Laboratories: Lessons Learned From a Swiss-Wide Proficiency Test
  53. OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more
  54. A generalized Robinson-Foulds distance for labeled trees
  55. Parallel and Scalable Precise Clustering
  56. A Linear Time Solution to the Labeled Robinson-Foulds Distance Problem
  57. A putative origin of insect chemosensory receptors in the last common eukaryotic ancestor
  58. Large scale phylogenetic profiling and investigating gene networks involved in sexual reproduction
  59. A hands-on introduction to querying evolutionary relationships across multiple data sources using SPARQL
  60. Benchmarking gene ontology function predictions using negative annotations
  61. Only a Single Taxonomically Restricted Gene Family in the Drosophila melanogaster Subgroup Can Be Identified with High Confidence
  62. Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria
  63. How to build phylogenetic species trees with OMA
  64. The phylogenetic range of bacterial and viral pathogens of vertebrates
  65. Corrigendum: OMA standalone: orthology inference among public and custom genomes and transcriptomes
  66. The Quest for Orthologs benchmark service and consensus calls in 2020
  67. Genomic Encryption of Digital Data Stored in Synthetic DNA
  68. New genome assembly of the barn owl ( Tyto alba alba )
  69. Identifying orthologs with OMA: A primer
  70. Scalable Phylogenetic Profiling using MinHash Uncovers Likely Eukaryotic Sexual Reproduction Genes
  71. Structural variant calling: the long and the short of it
  72. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
  73. Genomic encryption of digital data stored in synthetic DNA
  74. A hands-on introduction to querying evolutionary relationships across multiple data sources using SPARQL
  75. Parallel and Scalable Precise Clustering for Homologous Protein Discovery
  76. Enabling Semantic Queries Across Federated Bioinformatics Databases
  77. Advances and Applications in the Quest for Orthologs
  78. OMA standalone: orthology inference among public and custom genomes and transcriptomes
  79. The phylogenetic range of bacterial and viral pathogens of vertebrates
  80. Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria
  81. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
  82. Expanding the Orthologous Matrix (OMA) programmatic interfaces: REST API and the OmaDB packages for R and Python
  83. Assigning confidence scores to homoeologs using fuzzy logic
  84. Expanding the Orthologous Matrix (OMA) programmatic interfaces: REST API and the OmaDB packages for R and Python
  85. Inferring Orthology and Paralogy
  86. Enabling semantic queries across federated bioinformatics databases
  87. VoIDext: Vocabulary and Patterns for Enhancing Interoperable Datasets with Virtual Links
  88. How Much Does GenoGuard Really "Guard"?
  89. iHam & pyHam: visualizing and processing hierarchical orthologous groups
  90. Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
  91. Prioritising candidate genes causing QTL using hierarchical orthologous groups
  92. OMA standalone: orthology inference among public and custom genomes and transcriptomes
  93. GOATOOLS: A Python library for Gene Ontology analyses
  94. Submit a Topic Page to PLOS Computational Biology and Wikipedia
  95. RecPhyloXML - a format for reconciled gene trees
  96. The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces
  97. Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
  98. Assessing the potential of RAD-sequencing to resolve phylogenetic relationships within species radiations: The fly genus Chiastocheta (Diptera: Anthomyiidae) as a case study
  99. Lessons Learned: Recommendations for Establishing Critical Periodic Scientific Benchmarking
  100. Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
  101. Taxon sampling unequally affects individual nodes in a phylogenetic tree: consequences for model gene tree construction in SwissTree
  102. Orthologous Matrix (OMA) algorithm 2.0: more robust to asymmetric evolutionary rates and more scalable hierarchical orthologous group inference
  103. Tracking the Evolution of Non–Small-Cell Lung Cancer
  104. Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
  105. Comparative genomics reveals contraction in olfactory receptor genes in bats
  106. Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast
  107. The Gene Ontology Handbook
  108. OUP accepted manuscript
  109. A Gene Ontology Tutorial in Python
  110. Gene Ontology: Pitfalls, Biases, and Remedies
  111. Primer on the Gene Ontology
  112. An expanded evaluation of protein function prediction methods shows an improvement in accuracy
  113. Membrane Proteins Are Dramatically Less Conserved than Water-Soluble Proteins across the Tree of Life
  114. Homoeologs: What Are They and How Do We Infer Them?
  115. Phylo.io: Interactive Viewing and Comparison of Large Phylogenetic Trees on the Web
  116. Transient structural variations alter gene expression and quantitative traits in Schizosaccharomyces pombe.
  117. Standardized benchmarking in the quest for orthologs
  118. Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome
  119. Clustering Genes of Common Evolutionary History
  120. Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference
  121. Inferring Horizontal Gene Transfer
  122. A Transcriptomic-Phylogenomic Analysis of the Evolutionary Relationships of Flatworms
  123. Phylogenetic Profiling: How Much Input Data Is Enough?
  124. Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks
  125. The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease
  126. The OMA orthology database in 2015: function predictions, better plant support, synteny view and other improvements
  127. Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology
  128. Big data and other challenges in the quest for orthologs
  129. Preface of Proceedings of GNOME 2014 — Festschrift for Gaston Gonnet
  130. CAFA and the Open World of protein function predictions
  131. Bidirectional Best Hits Miss Many Orthologs in Duplication-Rich Clades such as Plants and Animals
  132. Who Watches the Watchmen? An Appraisal of Benchmarks for Multiple Sequence Alignment
  133. The Impact of Gene Duplication, Insertion, Deletion, Lateral Gene Transfer and Sequencing Error on Orthology Inference: A Simulation Study
  134. Towards practical, high-capacity, low-maintenance information storage in synthesized DNA
  135. Inferring Hierarchical Orthologous Groups from Orthologous Gene Pairs
  136. Approximate Bayesian Computation
  137. Global regulatory architecture of human, mouse and rat tissue transcriptomes
  138. Quality of Computationally Inferred Gene Ontology Annotations
  139. Resolving the Ortholog Conjecture: Orthologs Tend to Be Weakly, but Significantly, More Similar in Function than Paralogs
  140. Toward community standards in the quest for orthologs
  141. Inferring Orthology and Paralogy
  142. ALF--A Simulation Framework for Genome Evolution
  143. Editorial: Orthology and applications
  144. Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees
  145. Comparative genomics approach to detecting split-coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes)
  146. iTRAQ-based analysis of changes in the cassava root proteome reveals pathways associated with post-harvest physiological deterioration
  147. Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes
  148. The what, where, how and why of gene ontology--a primer for bioinformaticians
  149. Base-calling for next-generation sequencing platforms
  150. OMA 2011: orthology inference among 1000 complete genomes
  151. Phylogenetic assessment of alignments reveals neglected tree signal in gaps
  152. The Microbe browser for comparative genomics
  153. Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods
  154. Algorithm of OMA for large-scale orthology inference
  155. Joining forces in the quest for orthologs
  156. Evaluating the robustness of phylogenetic methods to among-site variability in substitution processes
  157. Algorithm of OMA for large-scale orthology inference
  158. Covariance of maximum likelihood evolutionary distances between sequences aligned pairwise
  159. SWPS3 – fast multi-threaded vectorized Smith-Waterman for IBM Cell/B.E. and ×86/SSE2
  160. Alignments with non-overlapping moves, inversions and tandem duplications in O(n 4) time
  161. OMA Browser Exploring orthologous relations across 352 complete genomes
  162. Detecting non-orthology in the COGs database and other approaches grouping orthologs using genome-specific best hits
  163. A DIMENSIONLESS FIT MEASURE FOR PHYLOGENETIC DISTANCE TREES
  164. OMA, A Comprehensive, Automated Project for the Identification of Orthologs from Complete Genome Data: Introduction and First Achievements
  165. DLIGHT – Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework
  166. Alignments with Non-overlapping Moves, Inversions and Tandem Duplications in O(n 4) Time