All Stories

  1. The missing link in FAIR data policy: biodata resources in life sciences
  2. AmpliPhy improves gene trees by adding homologs without affecting alignments
  3. OMAnnotator: a novel approach to building an annotated consensus genome sequence
  4. PhytClust: efficient and optimal node clustering in phylogenetic trees
  5. Quest for Orthologs in the era of Data Deluge and AI: Challenges and Innovations in Orthology Prediction and Data Integration
  6. Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses
  7. OrthoXML-Tools: A Toolkit for Manipulating OrthoXML Files for Orthology Data
  8. EdgeHOG: a method for fine-grained ancestral gene order inference at large scale
  9. Unveiling the functional fate of duplicated genes through expression profiling and structural analysis
  10. Invest in data resources to make FAIR a reality
  11. Annotation matters: the effect of structural gene annotation on orthology inference
  12. Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs
  13. Orthology inference at scale with FastOMA
  14. OMAnnotator: a novel approach to building an annotated consensus genome sequence
  15. Reconstructing the last common ancestor of all eukaryotes
  16. When less is more: sketching with minimizers in genomics
  17. Quest for Orthologs in the Era of Biodiversity Genomics
  18. New developments for the Quest for Orthologs benchmark service
  19. EdgeHOG: fine-grained ancestral gene order inference at tree-of-life scale
  20. Matreex: Compact and Interactive Visualization for Scalable Studies of Large Gene Families
  21. Frequent jumps from human hosts
  22. AI and the democratization of knowledge
  23. Quality assessment of gene repertoire annotations with OMArk
  24. Orthology inference at scale with FastOMA
  25. DrosOMA: the Drosophila Orthologous Matrix browser
  26. OMA orthology in 2024: improved prokaryote coverage, ancestral and extant GO enrichment, a revamped synteny viewer and more in the OMA Ecosystem
  27. The SIB Swiss Institute of Bioinformatics Semantic Web of data
  28. Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses
  29. Exploring Disease Model Mouse Using Knowledge Graphs: Combining Gene Expression, Orthology, and Disease Datasets
  30. Protein length distribution is remarkably uniform across the tree of life
  31. Phylogenetic profiling in eukaryotes comes of age
  32. Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree
  33. Protein S-acylation controls the subcellular localization and biological activity of PHYTOCHROME KINASE SUBSTRATE
  34. Matreex: compact and interactive visualisation for scalable studies of large gene families
  35. Bringing science to the public in the light of evolution
  36. Multifaceted quality assessment of gene repertoire annotation with OMArk
  37. Reconstructing protein interactions across time using phylogeny-aware graph neural networks
  38. Bio-SODA UX: enabling natural language question answering over knowledge graphs with user disambiguation
  39. Control of PHYTOCHROME KINASE SUBSTRATE subcellular localization and biological activity by protein S-acylation
  40. Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
  41. ISMB 2022 proceedings
  42. The Quest for Orthologs orthology benchmark service in 2022
  43. Read2Tree: scalable and accurate phylogenetic trees from raw reads
  44. A Linear Time Solution to the Labeled Robinson–Foulds Distance Problem
  45. OMAMO: orthology-based alternative model organism selection
  46. How to build phylogenetic species trees with OMA
  47. Citrullination Was Introduced into Animals by Horizontal Gene Transfer from Cyanobacteria
  48. Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
  49. Bio-SODA: Enabling Natural Language Question Answering over Knowledge Graphs without Training Data
  50. ISMB/ECCB 2021 proceedings
  51. Homoeolog Inference Methods Requiring Bidirectional Best Hits or Synteny Miss Many Pairs
  52. Ten Years of Collaborative Progress in the Quest for Orthologs
  53. OMAmer: tree-driven and alignment-free protein assignment to subfamilies outperforms closest sequence approaches
  54. Want to track pandemic variants faster? Fix the bioinformatics bottleneck
  55. Gene Duplication and Gain in the Trematode Atriophallophorus winterbourni Contributes to Adaptation to Parasitism
  56. A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor
  57. NGS-Based S. aureus Typing and Outbreak Analysis in Clinical Microbiology Laboratories: Lessons Learned From a Swiss-Wide Proficiency Test
  58. OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more
  59. A generalized Robinson-Foulds distance for labeled trees
  60. Parallel and Scalable Precise Clustering
  61. A Linear Time Solution to the Labeled Robinson-Foulds Distance Problem
  62. A putative origin of insect chemosensory receptors in the last common eukaryotic ancestor
  63. Large scale phylogenetic profiling and investigating gene networks involved in sexual reproduction
  64. A hands-on introduction to querying evolutionary relationships across multiple data sources using SPARQL
  65. Benchmarking gene ontology function predictions using negative annotations
  66. Only a Single Taxonomically Restricted Gene Family in the Drosophila melanogaster Subgroup Can Be Identified with High Confidence
  67. Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria
  68. How to build phylogenetic species trees with OMA
  69. The phylogenetic range of bacterial and viral pathogens of vertebrates
  70. Corrigendum: OMA standalone: orthology inference among public and custom genomes and transcriptomes
  71. The Quest for Orthologs benchmark service and consensus calls in 2020
  72. Genomic Encryption of Digital Data Stored in Synthetic DNA
  73. New genome assembly of the barn owl ( Tyto alba alba )
  74. Identifying orthologs with OMA: A primer
  75. Scalable Phylogenetic Profiling using MinHash Uncovers Likely Eukaryotic Sexual Reproduction Genes
  76. Structural variant calling: the long and the short of it
  77. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
  78. Genomic encryption of digital data stored in synthetic DNA
  79. A hands-on introduction to querying evolutionary relationships across multiple data sources using SPARQL
  80. Parallel and Scalable Precise Clustering for Homologous Protein Discovery
  81. Enabling Semantic Queries Across Federated Bioinformatics Databases
  82. Advances and Applications in the Quest for Orthologs
  83. OMA standalone: orthology inference among public and custom genomes and transcriptomes
  84. The phylogenetic range of bacterial and viral pathogens of vertebrates
  85. Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria
  86. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
  87. Expanding the Orthologous Matrix (OMA) programmatic interfaces: REST API and the OmaDB packages for R and Python
  88. Assigning confidence scores to homoeologs using fuzzy logic
  89. Expanding the Orthologous Matrix (OMA) programmatic interfaces: REST API and the OmaDB packages for R and Python
  90. Inferring Orthology and Paralogy
  91. Enabling semantic queries across federated bioinformatics databases
  92. VoIDext: Vocabulary and Patterns for Enhancing Interoperable Datasets with Virtual Links
  93. How Much Does GenoGuard Really "Guard"?
  94. iHam & pyHam: visualizing and processing hierarchical orthologous groups
  95. Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
  96. Prioritising candidate genes causing QTL using hierarchical orthologous groups
  97. OMA standalone: orthology inference among public and custom genomes and transcriptomes
  98. GOATOOLS: A Python library for Gene Ontology analyses
  99. Submit a Topic Page to PLOS Computational Biology and Wikipedia
  100. RecPhyloXML - a format for reconciled gene trees
  101. The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces
  102. Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
  103. Assessing the potential of RAD-sequencing to resolve phylogenetic relationships within species radiations: The fly genus Chiastocheta (Diptera: Anthomyiidae) as a case study
  104. Lessons Learned: Recommendations for Establishing Critical Periodic Scientific Benchmarking
  105. Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
  106. Taxon sampling unequally affects individual nodes in a phylogenetic tree: consequences for model gene tree construction in SwissTree
  107. Orthologous Matrix (OMA) algorithm 2.0: more robust to asymmetric evolutionary rates and more scalable hierarchical orthologous group inference
  108. Tracking the Evolution of Non–Small-Cell Lung Cancer
  109. Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
  110. Comparative genomics reveals contraction in olfactory receptor genes in bats
  111. Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast
  112. The Gene Ontology Handbook
  113. OUP accepted manuscript
  114. A Gene Ontology Tutorial in Python
  115. Gene Ontology: Pitfalls, Biases, and Remedies
  116. Primer on the Gene Ontology
  117. An expanded evaluation of protein function prediction methods shows an improvement in accuracy
  118. Membrane Proteins Are Dramatically Less Conserved than Water-Soluble Proteins across the Tree of Life
  119. Homoeologs: What Are They and How Do We Infer Them?
  120. Phylo.io: Interactive Viewing and Comparison of Large Phylogenetic Trees on the Web
  121. Transient structural variations alter gene expression and quantitative traits in Schizosaccharomyces pombe.
  122. Standardized benchmarking in the quest for orthologs
  123. Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome
  124. Clustering Genes of Common Evolutionary History
  125. Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference
  126. Inferring Horizontal Gene Transfer
  127. A Transcriptomic-Phylogenomic Analysis of the Evolutionary Relationships of Flatworms
  128. Phylogenetic Profiling: How Much Input Data Is Enough?
  129. Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks
  130. The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease
  131. The OMA orthology database in 2015: function predictions, better plant support, synteny view and other improvements
  132. Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology
  133. Big data and other challenges in the quest for orthologs
  134. Preface of Proceedings of GNOME 2014 — Festschrift for Gaston Gonnet
  135. CAFA and the Open World of protein function predictions
  136. Bidirectional Best Hits Miss Many Orthologs in Duplication-Rich Clades such as Plants and Animals
  137. Who Watches the Watchmen? An Appraisal of Benchmarks for Multiple Sequence Alignment
  138. The Impact of Gene Duplication, Insertion, Deletion, Lateral Gene Transfer and Sequencing Error on Orthology Inference: A Simulation Study
  139. Towards practical, high-capacity, low-maintenance information storage in synthesized DNA
  140. Inferring Hierarchical Orthologous Groups from Orthologous Gene Pairs
  141. Approximate Bayesian Computation
  142. Global regulatory architecture of human, mouse and rat tissue transcriptomes
  143. Quality of Computationally Inferred Gene Ontology Annotations
  144. Resolving the Ortholog Conjecture: Orthologs Tend to Be Weakly, but Significantly, More Similar in Function than Paralogs
  145. Toward community standards in the quest for orthologs
  146. Inferring Orthology and Paralogy
  147. ALF--A Simulation Framework for Genome Evolution
  148. Editorial: Orthology and applications
  149. Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees
  150. Comparative genomics approach to detecting split-coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes)
  151. iTRAQ-based analysis of changes in the cassava root proteome reveals pathways associated with post-harvest physiological deterioration
  152. Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes
  153. The what, where, how and why of gene ontology--a primer for bioinformaticians
  154. Base-calling for next-generation sequencing platforms
  155. OMA 2011: orthology inference among 1000 complete genomes
  156. Phylogenetic assessment of alignments reveals neglected tree signal in gaps
  157. The Microbe browser for comparative genomics
  158. Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods
  159. Algorithm of OMA for large-scale orthology inference
  160. Joining forces in the quest for orthologs
  161. Evaluating the robustness of phylogenetic methods to among-site variability in substitution processes
  162. Algorithm of OMA for large-scale orthology inference
  163. Covariance of maximum likelihood evolutionary distances between sequences aligned pairwise
  164. SWPS3 – fast multi-threaded vectorized Smith-Waterman for IBM Cell/B.E. and ×86/SSE2
  165. Alignments with non-overlapping moves, inversions and tandem duplications in O(n 4) time
  166. OMA Browser Exploring orthologous relations across 352 complete genomes
  167. Detecting non-orthology in the COGs database and other approaches grouping orthologs using genome-specific best hits
  168. A DIMENSIONLESS FIT MEASURE FOR PHYLOGENETIC DISTANCE TREES
  169. OMA, A Comprehensive, Automated Project for the Identification of Orthologs from Complete Genome Data: Introduction and First Achievements
  170. DLIGHT – Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework
  171. Alignments with Non-overlapping Moves, Inversions and Tandem Duplications in O(n 4) Time