All Stories

  1. PhytClust: efficient and optimal node clustering in phylogenetic trees
  2. Quest for Orthologs in the era of Data Deluge and AI: Challenges and Innovations in Orthology Prediction and Data Integration
  3. Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses
  4. OrthoXML-Tools: A Toolkit for Manipulating OrthoXML Files for Orthology Data
  5. EdgeHOG: a method for fine-grained ancestral gene order inference at large scale
  6. Unveiling the functional fate of duplicated genes through expression profiling and structural analysis
  7. Invest in data resources to make FAIR a reality
  8. Annotation matters: the effect of structural gene annotation on orthology inference
  9. Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs
  10. Orthology inference at scale with FastOMA
  11. OMAnnotator: a novel approach to building an annotated consensus genome sequence
  12. Reconstructing the last common ancestor of all eukaryotes
  13. When less is more: sketching with minimizers in genomics
  14. Quest for Orthologs in the Era of Biodiversity Genomics
  15. New developments for the Quest for Orthologs benchmark service
  16. EdgeHOG: fine-grained ancestral gene order inference at tree-of-life scale
  17. Matreex: Compact and Interactive Visualization for Scalable Studies of Large Gene Families
  18. Frequent jumps from human hosts
  19. AI and the democratization of knowledge
  20. Quality assessment of gene repertoire annotations with OMArk
  21. Orthology inference at scale with FastOMA
  22. DrosOMA: the Drosophila Orthologous Matrix browser
  23. OMA orthology in 2024: improved prokaryote coverage, ancestral and extant GO enrichment, a revamped synteny viewer and more in the OMA Ecosystem
  24. The SIB Swiss Institute of Bioinformatics Semantic Web of data
  25. Structural phylogenetics unravels the evolutionary diversification of communication systems in gram-positive bacteria and their viruses
  26. Exploring Disease Model Mouse Using Knowledge Graphs: Combining Gene Expression, Orthology, and Disease Datasets
  27. Protein length distribution is remarkably uniform across the tree of life
  28. Phylogenetic profiling in eukaryotes comes of age
  29. Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree
  30. Protein S-acylation controls the subcellular localization and biological activity of PHYTOCHROME KINASE SUBSTRATE
  31. Matreex: compact and interactive visualisation for scalable studies of large gene families
  32. Bringing science to the public in the light of evolution
  33. Multifaceted quality assessment of gene repertoire annotation with OMArk
  34. Reconstructing protein interactions across time using phylogeny-aware graph neural networks
  35. Bio-SODA UX: enabling natural language question answering over knowledge graphs with user disambiguation
  36. Control of PHYTOCHROME KINASE SUBSTRATE subcellular localization and biological activity by protein S-acylation
  37. Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
  38. ISMB 2022 proceedings
  39. The Quest for Orthologs orthology benchmark service in 2022
  40. Read2Tree: scalable and accurate phylogenetic trees from raw reads
  41. A Linear Time Solution to the Labeled Robinson–Foulds Distance Problem
  42. OMAMO: orthology-based alternative model organism selection
  43. How to build phylogenetic species trees with OMA
  44. Citrullination Was Introduced into Animals by Horizontal Gene Transfer from Cyanobacteria
  45. Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
  46. Bio-SODA: Enabling Natural Language Question Answering over Knowledge Graphs without Training Data
  47. ISMB/ECCB 2021 proceedings
  48. Homoeolog Inference Methods Requiring Bidirectional Best Hits or Synteny Miss Many Pairs
  49. Ten Years of Collaborative Progress in the Quest for Orthologs
  50. OMAmer: tree-driven and alignment-free protein assignment to subfamilies outperforms closest sequence approaches
  51. Want to track pandemic variants faster? Fix the bioinformatics bottleneck
  52. Gene Duplication and Gain in the Trematode Atriophallophorus winterbourni Contributes to Adaptation to Parasitism
  53. A putative origin of the insect chemosensory receptor superfamily in the last common eukaryotic ancestor
  54. NGS-Based S. aureus Typing and Outbreak Analysis in Clinical Microbiology Laboratories: Lessons Learned From a Swiss-Wide Proficiency Test
  55. OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more
  56. A generalized Robinson-Foulds distance for labeled trees
  57. Parallel and Scalable Precise Clustering
  58. A Linear Time Solution to the Labeled Robinson-Foulds Distance Problem
  59. A putative origin of insect chemosensory receptors in the last common eukaryotic ancestor
  60. Large scale phylogenetic profiling and investigating gene networks involved in sexual reproduction
  61. A hands-on introduction to querying evolutionary relationships across multiple data sources using SPARQL
  62. Benchmarking gene ontology function predictions using negative annotations
  63. Only a Single Taxonomically Restricted Gene Family in the Drosophila melanogaster Subgroup Can Be Identified with High Confidence
  64. Protein citrullination was introduced into animals by horizontal gene transfer from cyanobacteria
  65. How to build phylogenetic species trees with OMA
  66. The phylogenetic range of bacterial and viral pathogens of vertebrates
  67. Corrigendum: OMA standalone: orthology inference among public and custom genomes and transcriptomes
  68. The Quest for Orthologs benchmark service and consensus calls in 2020
  69. Genomic Encryption of Digital Data Stored in Synthetic DNA
  70. New genome assembly of the barn owl ( Tyto alba alba )
  71. Identifying orthologs with OMA: A primer
  72. Scalable Phylogenetic Profiling using MinHash Uncovers Likely Eukaryotic Sexual Reproduction Genes
  73. Structural variant calling: the long and the short of it
  74. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
  75. Genomic encryption of digital data stored in synthetic DNA
  76. A hands-on introduction to querying evolutionary relationships across multiple data sources using SPARQL
  77. Parallel and Scalable Precise Clustering for Homologous Protein Discovery
  78. Enabling Semantic Queries Across Federated Bioinformatics Databases
  79. Advances and Applications in the Quest for Orthologs
  80. OMA standalone: orthology inference among public and custom genomes and transcriptomes
  81. The phylogenetic range of bacterial and viral pathogens of vertebrates
  82. Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria
  83. The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens
  84. Expanding the Orthologous Matrix (OMA) programmatic interfaces: REST API and the OmaDB packages for R and Python
  85. Assigning confidence scores to homoeologs using fuzzy logic
  86. Expanding the Orthologous Matrix (OMA) programmatic interfaces: REST API and the OmaDB packages for R and Python
  87. Inferring Orthology and Paralogy
  88. Enabling semantic queries across federated bioinformatics databases
  89. VoIDext: Vocabulary and Patterns for Enhancing Interoperable Datasets with Virtual Links
  90. How Much Does GenoGuard Really "Guard"?
  91. iHam & pyHam: visualizing and processing hierarchical orthologous groups
  92. Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
  93. Prioritising candidate genes causing QTL using hierarchical orthologous groups
  94. OMA standalone: orthology inference among public and custom genomes and transcriptomes
  95. GOATOOLS: A Python library for Gene Ontology analyses
  96. Submit a Topic Page to PLOS Computational Biology and Wikipedia
  97. RecPhyloXML - a format for reconciled gene trees
  98. The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces
  99. Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
  100. Assessing the potential of RAD-sequencing to resolve phylogenetic relationships within species radiations: The fly genus Chiastocheta (Diptera: Anthomyiidae) as a case study
  101. Lessons Learned: Recommendations for Establishing Critical Periodic Scientific Benchmarking
  102. Phylogenetic approaches to identifying fragments of the same gene, with application to the wheat genome
  103. Taxon sampling unequally affects individual nodes in a phylogenetic tree: consequences for model gene tree construction in SwissTree
  104. Orthologous Matrix (OMA) algorithm 2.0: more robust to asymmetric evolutionary rates and more scalable hierarchical orthologous group inference
  105. Tracking the Evolution of Non–Small-Cell Lung Cancer
  106. Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
  107. Comparative genomics reveals contraction in olfactory receptor genes in bats
  108. Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast
  109. The Gene Ontology Handbook
  110. OUP accepted manuscript
  111. A Gene Ontology Tutorial in Python
  112. Gene Ontology: Pitfalls, Biases, and Remedies
  113. Primer on the Gene Ontology
  114. An expanded evaluation of protein function prediction methods shows an improvement in accuracy
  115. Membrane Proteins Are Dramatically Less Conserved than Water-Soluble Proteins across the Tree of Life
  116. Homoeologs: What Are They and How Do We Infer Them?
  117. Phylo.io: Interactive Viewing and Comparison of Large Phylogenetic Trees on the Web
  118. Transient structural variations alter gene expression and quantitative traits in Schizosaccharomyces pombe.
  119. Standardized benchmarking in the quest for orthologs
  120. Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome
  121. Clustering Genes of Common Evolutionary History
  122. Current Methods for Automated Filtering of Multiple Sequence Alignments Frequently Worsen Single-Gene Phylogenetic Inference
  123. Inferring Horizontal Gene Transfer
  124. A Transcriptomic-Phylogenomic Analysis of the Evolutionary Relationships of Flatworms
  125. Phylogenetic Profiling: How Much Input Data Is Enough?
  126. Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks
  127. The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease
  128. The OMA orthology database in 2015: function predictions, better plant support, synteny view and other improvements
  129. Speeding up all-against-all protein comparisons while maintaining sensitivity by considering subsequence-level homology
  130. Big data and other challenges in the quest for orthologs
  131. Preface of Proceedings of GNOME 2014 — Festschrift for Gaston Gonnet
  132. CAFA and the Open World of protein function predictions
  133. Bidirectional Best Hits Miss Many Orthologs in Duplication-Rich Clades such as Plants and Animals
  134. Who Watches the Watchmen? An Appraisal of Benchmarks for Multiple Sequence Alignment
  135. The Impact of Gene Duplication, Insertion, Deletion, Lateral Gene Transfer and Sequencing Error on Orthology Inference: A Simulation Study
  136. Towards practical, high-capacity, low-maintenance information storage in synthesized DNA
  137. Inferring Hierarchical Orthologous Groups from Orthologous Gene Pairs
  138. Approximate Bayesian Computation
  139. Global regulatory architecture of human, mouse and rat tissue transcriptomes
  140. Quality of Computationally Inferred Gene Ontology Annotations
  141. Resolving the Ortholog Conjecture: Orthologs Tend to Be Weakly, but Significantly, More Similar in Function than Paralogs
  142. Toward community standards in the quest for orthologs
  143. Inferring Orthology and Paralogy
  144. ALF--A Simulation Framework for Genome Evolution
  145. Editorial: Orthology and applications
  146. Conceptual framework and pilot study to benchmark phylogenomic databases based on reference gene trees
  147. Comparative genomics approach to detecting split-coding regions in a low-coverage genome: lessons from the chimaera Callorhinchus milii (Holocephali, Chondrichthyes)
  148. iTRAQ-based analysis of changes in the cassava root proteome reveals pathways associated with post-harvest physiological deterioration
  149. Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes
  150. The what, where, how and why of gene ontology--a primer for bioinformaticians
  151. Base-calling for next-generation sequencing platforms
  152. OMA 2011: orthology inference among 1000 complete genomes
  153. Phylogenetic assessment of alignments reveals neglected tree signal in gaps
  154. The Microbe browser for comparative genomics
  155. Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods
  156. Algorithm of OMA for large-scale orthology inference
  157. Joining forces in the quest for orthologs
  158. Evaluating the robustness of phylogenetic methods to among-site variability in substitution processes
  159. Algorithm of OMA for large-scale orthology inference
  160. Covariance of maximum likelihood evolutionary distances between sequences aligned pairwise
  161. SWPS3 – fast multi-threaded vectorized Smith-Waterman for IBM Cell/B.E. and ×86/SSE2
  162. Alignments with non-overlapping moves, inversions and tandem duplications in O(n 4) time
  163. OMA Browser Exploring orthologous relations across 352 complete genomes
  164. Detecting non-orthology in the COGs database and other approaches grouping orthologs using genome-specific best hits
  165. A DIMENSIONLESS FIT MEASURE FOR PHYLOGENETIC DISTANCE TREES
  166. OMA, A Comprehensive, Automated Project for the Identification of Orthologs from Complete Genome Data: Introduction and First Achievements
  167. DLIGHT – Lateral Gene Transfer Detection Using Pairwise Evolutionary Distances in a Statistical Framework
  168. Alignments with Non-overlapping Moves, Inversions and Tandem Duplications in O(n 4) Time