All Stories

  1. Initial experience from a renal genetics clinic demonstrates a distinct role in patient management

    Article • Genetics in Medicine, June 2020, Elsevier

    Christie Thomas

  2. Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases

    Article • Nephrology Dialysis Transplantation, November 2019, Oxford University Press (OUP)

    Christie Thomas

  3. Billing for Living Kidney Donor Care: Balancing Cost Recovery, Regulatory Compliance, and Minimized Donor Burden

    Article • Current Transplantation Reports, April 2019, Springer Science + Business Media

    Christie Thomas

  4. Diagnosis of monogenic chronic kidney diseases

    Article • Current Opinion in Nephrology & Hypertension, March 2019, Wolters Kluwer Health

    Christie Thomas

  5. Unusual presentation of Q fever in a kidney‐pancreas transplant recipient

    Article • Transplant Infectious Disease, December 2018, Wiley

    Christie Thomas

  6. Genetic Analysis of 400 Patients Refines Understanding and Implicates a New Gene in Atypical Hemolytic Uremic Syndrome

    Article • Journal of the American Society of Nephrology, October 2018, American Society of Nephrology

    Christie Thomas

  7. VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis

    Article • AJP Cell Physiology, August 2018, American Physiological Society

    Christie Thomas

  8. EGF regulation of proximal tubule cell proliferation and VEGF‐A secretion

    Article • Physiological Reports, September 2017, Wiley

    Christie Thomas

  9. Has the Department of Veterans Affairs Found a Way to Avoid Racial Disparities in the Evaluation Process for Kidney Transplantation?

    Article • Transplantation, June 2017, Wolters Kluwer Health

    Dr. Larissa Myaskovsky, Christie Thomas

  10. Aldosterone regulates a 5ʹ variant sgk1 transcript via a shared hormone response element in the sgk1 5ʹ regulatory region

    Article • Physiological Reports, April 2017, Wiley

    Christie Thomas

  11. An Unexpected Surge in Plasma BKPyV Viral Load Heralds the Development of BKPyV-Associated Metastatic Bladder Cancer in a Lung Transplant Recipient With BKPyV Nephropathy

    Article • American Journal of Transplantation, March 2017, Elsevier

    Christie Thomas

  12. Screening of Living Kidney Donors for Genetic Diseases Using a Comprehensive Genetic Testing Strategy

    Article • American Journal of Transplantation, February 2017, Elsevier

    Christie Thomas

  13. Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene

    Article • Molecular Immunology, September 2016, Elsevier

    Christie Thomas

  14. Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage

    Article • Experimental Cell Research, May 2016, Elsevier

    Christie Thomas

  15. High-Throughput Genetic Testing for Thrombotic Microangiopathies and C3 Glomerulopathies

    Article • Journal of the American Society of Nephrology, April 2016, Wolters Kluwer Health

    Christie Thomas

  16. Light Chain Deposition Disease After Kidney Transplantation With Long Graft Survival: Case Report

    Article • Transplantation Proceedings, January 2016, Elsevier

    Christie Thomas

  17. BK polyoma virus infection and renal disease in non-renal solid organ transplantation

    Article • Clinical Kidney Journal, December 2015, Oxford University Press (OUP)

    Christie Thomas

  18. Antiproteinuric therapy and Fabry nephropathy: factors associated with preserved kidney function during agalsidase-beta therapy

    Article • Journal of Medical Genetics, October 2015, BMJ

    Dr Bojan Vujkovac, Christie Thomas

  19. Eculizumab for rescue of thrombotic microangiopathy in PM-Scl antibody-positive autoimmune overlap syndrome

    Article • Clinical Kidney Journal, October 2015, Oxford University Press (OUP)

    Christie Thomas

  20. Primary Cutaneous Polymorphic EBV-Associated Posttransplant Lymphoproliferative Disorder After a Renal Transplant and Review of the Literature

    Article • American Journal of Dermatopathology, October 2015, Wolters Kluwer Health

    Christie Thomas

  21. Soluble C5b-9 as a Biomarker for Complement Activation in Atypical Hemolytic Uremic Syndrome

    Article • American Journal of Kidney Diseases, June 2015, Elsevier

    Christie Thomas

  22. Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1

    Article • Placenta, April 2015, Elsevier

    Christie Thomas

  23. The Challenge in Diagnosing De Novo Minimal Change Disease After Transplantation

    Article • Transplantation, February 2015, Wolters Kluwer Health

    Christie Thomas

  24. Conversion to a sirolimus‐based regimen is associated with lower incidence of BK viremia in low‐risk kidney transplant recipients

    Article • Transplant Infectious Disease, January 2015, Wiley

    Christie Thomas

  25. N-Terminal Cleavage and Release of the Ectodomain of Flt1 Is Mediated via ADAM10 and ADAM 17 and Regulated by VEGFR2 and the Flt1 Intracellular Domain

    Article • PLoS ONE, November 2014, PLOS

    Christie Thomas

  26. Late-Onset BK Viral Nephropathy in a Kidney Transplant Recipient

    Article • Transplantation Proceedings, September 2014, Elsevier

    Christie Thomas

  27. Comprehensive Genetic Analysis of Complement and Coagulation Genes in Atypical Hemolytic Uremic Syndrome

    Article • Journal of the American Society of Nephrology, January 2014, Wolters Kluwer Health

    Christie Thomas

  28. Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist

    Article • Experimental Cell Research, October 2013, Elsevier

    Christie Thomas

  29. Faculty Opinions recommendation of Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension.

    Article • June 2013, F1000Research

    Christie Thomas

  30. Quiz Page April 2013

    Article • American Journal of Kidney Diseases, April 2013, Elsevier

    Christie Thomas

  31. A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct

    Article • AJP Renal Physiology, December 2012, American Physiological Society

    Christie Thomas

  32. Case Report: Eculizumab Rescue of Severe Accelerated Antibody-Mediated Rejection After ABO-Incompatible Kidney Transplant

    Article • Transplantation Proceedings, December 2012, Elsevier

    Christie Thomas

  33. Tailored Eculizumab Therapy in the Management of Complement Factor H–Mediated Atypical Hemolytic Uremic Syndrome in an Adult Kidney Transplant Recipient: A Case Report

    Article • Transplantation Proceedings, December 2012, Elsevier

    Christie Thomas

  34. Secretion of Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1/sFlt1) Requires Arf1, Arf6, and Rab11 GTPases

    Article • PLoS ONE, September 2012, PLOS

    Christie Thomas

  35. Very Early Recurrence of Anti-Phospholipase A2 Receptor-Positive Membranous Nephropathy After Transplantation

    Article • American Journal of Transplantation, June 2012, Elsevier

    Christie Thomas

  36. Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression

    Article • Journal of Leukocyte Biology, March 2012, Oxford University Press (OUP)

    Christie Thomas

  37. Pre-emptive Eculizumab and Plasmapheresis for Renal Transplant in Atypical Hemolytic Uremic Syndrome

    Article • Clinical Journal of the American Society of Nephrology, June 2011, Wolters Kluwer Health

    Christie Thomas

  38. Dextran Removal by Plasmapheresis in a Kidney-Pancreas Transplant Recipient With Dextran 40–Induced Osmotic Nephrosis

    Article • American Journal of Kidney Diseases, April 2011, Elsevier

    Christie Thomas

  39. Nedd4–2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia

    Article • AJP Renal Physiology, August 2010, American Physiological Society

    Christie Thomas

  40. Alternate processing of Flt1 transcripts is directed by conserved cis -elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation

    Article • Nucleic Acids Research, April 2010, Oxford University Press (OUP)

    Christie Thomas

  41. Unrecognized Acute Phosphate Nephropathy in a Kidney Donor with Consequent Poor Allograft Outcome

    Article • American Journal of Transplantation, September 2009, Elsevier

    Christie Thomas

  42. A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia

    Article • The Journal of Clinical Endocrinology & Metabolism, July 2009, Endocrine Society

    Christie Thomas

  43. Recurrent Atypical Hemolytic Uremic Syndrome Associated With Factor I Mutation in a Living Related Renal Transplant Recipient

    Article • American Journal of Kidney Diseases, February 2009, Elsevier

    Christie Thomas

  44. An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function

    Article • AJP Renal Physiology, November 2008, American Physiological Society

    Christie Thomas

  45. A genetic syndrome of chronic renal failure with multiple renal cysts and early onset diabetes

    Article • Kidney International, October 2008, Elsevier

    Christie Thomas

  46. Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel

    Article • AJP Renal Physiology, May 2008, American Physiological Society

    Christie Thomas

  47. Serum/glucocorticoid-induced protein kinase-1 facilitates androgen receptor-dependent cell survival

    Article • Cell Death and Differentiation, October 2007, Springer Science + Business Media

    Christie Thomas

  48. Intronic polyadenylation signal sequences and alternate splicing generate human soluble Fltl variants and regulate the abundance of soluble Flt1 in the placenta

    Article • The FASEB Journal, July 2007, Wiley

    Christie Thomas

  49. Diffuse Glomerular Crescents and Peritubular Immune Deposits in a Transplant Kidney

    Article • American Journal of Kidney Diseases, July 2006, Elsevier

    Christie Thomas

  50. Medroxyprogesterone acetate binds the glucocorticoid receptor to stimulate α-ENaC and sgk1 expression in renal collecting duct epithelia

    Article • AJP Renal Physiology, February 2006, American Physiological Society

    Christie Thomas

  51. Nedd4–2 isoforms differentially associate with ENaC and regulate its activity

    Article • AJP Renal Physiology, August 2005, American Physiological Society

    Christie Thomas

  52. Early Postnephrectomy Donor Renal Function: Laparoscopic versus Open Procedure

    Article • Transplantation, March 2005, Wolters Kluwer Health

    Christie Thomas

  53. Dual Therapeutic Utility of Proteasome Modulating Agents for Pharmaco-gene Therapy of the Cystic Fibrosis Airway

    Article • Molecular Therapy, December 2004, Elsevier

    Christie Thomas

  54. cAMP-stimulated Na+transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1

    Article • AJP Lung Cellular and Molecular Physiology, October 2004, American Physiological Society

    Christie Thomas

  55. AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5′-flanking region of the VIT32 gene

    Article • AJP Renal Physiology, September 2004, American Physiological Society

    Christie Thomas

  56. New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis

    Article • Current Opinion in Nephrology & Hypertension, September 2004, Wolters Kluwer Health

    Christie Thomas

  57. Transcriptional repression of the CTP:phosphocholine cytidylyltransferase gene by sphingosine

    Article • Biochemical Journal, August 2004, Portland Press Ltd.

    Christie Thomas

  58. Systemic Pseudohypoaldosteronism from Deletion of the Promoter Region of the HumanβEpithelial Na+Channel Subunit

    Article • American Journal of Respiratory Cell and Molecular Biology, September 2002, American Thoracic Society

    Christie Thomas

  59. The  -Subunit of the Epithelial Sodium Channel Is an Aldosterone-Induced Transcript in Mammalian Collecting Ducts, and This Transcriptional Response Is Mediated via Distinct cis-Elements in the 5'-Flanking Region of the Gene

    Article • Molecular Endocrinology, April 2001, Endocrine Society

    Christie Thomas

  60. Glucocorticoid Induction of Epithelial Sodium Channel Expression in Lung and Renal Epithelia Occurs via trans-Activation of a Hormone Response Element in the 5′-Flanking Region of the Human Epithelial Sodium Channel α Subunit Gene

    Article • Journal of Biological Chemistry, April 1999, Elsevier

    Christie Thomas

  61. The structure of the rat amiloride-sensitive epithelial sodium channel gamma subunit gene and functional analysis of its promoter

    Article • Gene, March 1999, Elsevier

    Christie Thomas

  62. Genomic Organization and the 5′ Flanking Region of the γ Subunit of the Human Amiloride-sensitive Epithelial Sodium Channel

    Article • Journal of Biological Chemistry, October 1996, Elsevier

    Christie Thomas