All Stories

  1. Hepatitis C Virus (HCV) Recurrence and Death After Viral Clearance in an HCV-Viremic Donor to HCV-Negative Kidney Recipient
  2. Variants of unknown significance are common in brushite stone formers undergoing genetic testing for nephrolithiasis
  3. Educating the Next-Generation Expert in Nephrology Genetics
  4. Utility of Genetic Information for Management in Kidney Transplantation and Living Donation
  5. Outcomes of High Kidney Donor Profile Index Hepatitis C Nucleic Acid Testing Positive Kidneys are Equivalent to Matched Hepatitis C Nucleic Acid Testing Negative Kidneys
  6. Evaluation for genetic disease in kidney transplant candidates: A practice resource
  7. Late-onset retinal oxalosis in primary hyperoxaluria type 2
  8. Homozygous missense variants in YKT6 result in loss of function and are associated with developmental delay, with or without severe infantile liver disease and risk for hepatocellular carcinoma
  9. APOL1 Kidney Risk Variants and Long-Term Kidney Function in Healthy Middle-Aged Black Individuals: The Atherosclerosis Risk in Communities (ARIC) Study
  10. Screening of Living Kidney Donors for Genetic Diseases: CON
  11. Prevalence of kidney health genetic variants in adults with sickle cell nephropathy
  12. Genetic testing in the evaluation of recipient candidates and living kidney donors
  13. Lost in translation: Misguided application of a laudable and well-intentioned policy
  14. A randomized controlled trial of preemptive rituximab to prevent recurrent focal segmental glomerulosclerosis post-kidney transplant (PRI-VENT FSGS): protocol and study design
  15. Genetic evaluation of living kidney donor candidates: A review and recommendations for best practices
  16. Suspected Autosomal Recessive Polycystic Kidney Disease but Cerebellar Vermis Hypoplasia, Oligophrenia Ataxia, Coloboma, and Hepatic Fibrosis (COACH) Syndrome in Retrospect, A Delayed Diagnosis Aided by Genotyping and Reverse Phenotyping: A Case Report...
  17. Associations of Lack of Insurance and Other Sociodemographic Traits With Follow-up After Living Kidney Donation
  18. Severely Reduced Kidney Function Assessed by a Single eGFR Determination at the Time of an Isolated Heart Transplant Does Not Predict Inevitable Posttransplant ESKD
  19. Managing the Costs of Routine Follow-up Care After Living Kidney Donation: a Review and Survey of Contemporary Experience, Practices, and Challenges
  20. The U-shaped association of post-lung transplant mortality with pretransplant eGFR underscores possible limitations of creatinine-based estimation equations for risk stratification
  21. Monogenic focal segmental glomerulosclerosis: A conceptual framework for identification and management of a heterogeneous disease
  22. Familial hyperkalemic hypertension: hyperkalemia not hypertension defines dominant KLHL3 disease and may permit earlier recognition and tailored therapy
  23. Sequential genetic testing of living‐related donors for inherited renal disease to promote informed choice and enhance safety of living donation
  24. Integrating APOL1 Kidney-risk Variant Testing in Live Kidney Donor Evaluation: An Expert Panel Opinion
  25. Correction: Initial experience from a renal genetics clinic demonstrates a distinct role in patient management
  26. Case Report: Severe COVID-19 in a Kidney Transplant Recipient Without Humoral Response to SARS-CoV-2 mRNA Vaccine Series
  27. Impact of changing renal function, while waiting for a heart transplant, on post‐transplant mortality and development of end stage kidney disease
  28. Donor-derived human herpesvirus 8 and development of Kaposi sarcoma among 6 recipients of organs from donors with high-risk sexual and substance use behavior
  29. Minimal Change Disease With Nephrotic Syndrome Associated With Coronavirus Disease 2019 After Apolipoprotein L1 Risk Variant Kidney Transplant: A Case Report
  30. Infiltrating Kaposi sarcoma presenting as acute kidney injury: An unexpected consequence of deliberate hepatitis C–positive organ transplantation
  31. Spontaneous remission of genetic, apparent primary, FSGS presenting with nephrotic syndrome challenges traditional notions of primary FSGS
  32. A rare case of hyporeninemic hypertension: Answers
  33. A rare case of hyporeninemic hypertension: Questions
  34. Initial experience from a renal genetics clinic demonstrates a distinct role in patient management
  35. Estimated Glomerular Filtration Rate at Transplant Listing and Other Predictors of Post-Heart Transplant Mortality and the Development of ESRD
  36. KDOQI US Commentary on the 2017 KDIGO Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors
  37. Unexpected Race and Ethnicity Differences in the US National Veterans Affairs Kidney Transplant Program
  38. Targeted broad-based genetic testing by next-generation sequencing informs diagnosis and facilitates management in patients with kidney diseases
  39. Initial skin cancer screening for solid organ transplant recipients in the United States: Delphi method development of expert consensus guidelines
  40. Billing for Living Kidney Donor Care: Balancing Cost Recovery, Regulatory Compliance, and Minimized Donor Burden
  41. Diagnosis of monogenic chronic kidney diseases
  42. Unusual presentation of Q fever in a kidney‐pancreas transplant recipient
  43. Genetic Analysis of 400 Patients Refines Understanding and Implicates a New Gene in Atypical Hemolytic Uremic Syndrome
  44. VEGF-A selectively inhibits FLT1 ectodomain shedding independent of receptor activation and receptor endocytosis
  45. EGF regulation of proximal tubule cell proliferation and VEGF‐A secretion
  46. Late Reoccurrence of Collapsing FSGS After Transplantation of a Living-Related Kidney Bearing APOL 1 Risk Variants Without Disease Evident in Donor Supports the Second Hit Hypothesis
  47. Has the Department of Veterans Affairs Found a Way to Avoid Racial Disparities in the Evaluation Process for Kidney Transplantation?
  48. Aldosterone regulates a 5ʹ variant sgk1 transcript via a shared hormone response element in the sgk1 5ʹ regulatory region
  49. An Unexpected Surge in Plasma BKPyV Viral Load Heralds the Development of BKPyV-Associated Metastatic Bladder Cancer in a Lung Transplant Recipient With BKPyV Nephropathy
  50. Screening of Living Kidney Donors for Genetic Diseases Using a Comprehensive Genetic Testing Strategy
  51. Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene
  52. Ectodomain cleavage of FLT1 regulates receptor activation and function and is not required for its downstream intracellular cleavage
  53. High-Throughput Genetic Testing for Thrombotic Microangiopathies and C3 Glomerulopathies
  54. Light Chain Deposition Disease After Kidney Transplantation With Long Graft Survival: Case Report
  55. BK polyoma virus infection and renal disease in non-renal solid organ transplantation
  56. Antiproteinuric therapy and Fabry nephropathy: factors associated with preserved kidney function during agalsidase-beta therapy
  57. Eculizumab for rescue of thrombotic microangiopathy in PM-Scl antibody-positive autoimmune overlap syndrome
  58. Primary Cutaneous Polymorphic EBV-Associated Posttransplant Lymphoproliferative Disorder After a Renal Transplant and Review of the Literature
  59. Soluble C5b-9 as a Biomarker for Complement Activation in Atypical Hemolytic Uremic Syndrome
  60. Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1
  61. The Challenge in Diagnosing De Novo Minimal Change Disease After Transplantation
  62. Conversion to a sirolimus‐based regimen is associated with lower incidence of BK viremia in low‐risk kidney transplant recipients
  63. N-Terminal Cleavage and Release of the Ectodomain of Flt1 Is Mediated via ADAM10 and ADAM 17 and Regulated by VEGFR2 and the Flt1 Intracellular Domain
  64. Late-Onset BK Viral Nephropathy in a Kidney Transplant Recipient
  65. Comprehensive Genetic Analysis of Complement and Coagulation Genes in Atypical Hemolytic Uremic Syndrome
  66. Protein kinase C regulates FLT1 abundance and stimulates its cleavage in vascular endothelial cells with the release of a soluble PlGF/VEGF antagonist
  67. Faculty Opinions recommendation of Deficiency of renal cortical EGF increases ENaC activity and contributes to salt-sensitive hypertension.
  68. Quiz Page April 2013
  69. A regulated NH2-terminal Sgk1 variant with enhanced function is expressed in the collecting duct
  70. Case Report: Eculizumab Rescue of Severe Accelerated Antibody-Mediated Rejection After ABO-Incompatible Kidney Transplant
  71. Tailored Eculizumab Therapy in the Management of Complement Factor H–Mediated Atypical Hemolytic Uremic Syndrome in an Adult Kidney Transplant Recipient: A Case Report
  72. Secretion of Soluble Vascular Endothelial Growth Factor Receptor 1 (sVEGFR1/sFlt1) Requires Arf1, Arf6, and Rab11 GTPases
  73. Very Early Recurrence of Anti-Phospholipase A2 Receptor-Positive Membranous Nephropathy After Transplantation
  74. Coordinated DNA methylation and gene expression changes in smoker alveolar macrophages: specific effects on VEGF receptor 1 expression
  75. Pre-emptive Eculizumab and Plasmapheresis for Renal Transplant in Atypical Hemolytic Uremic Syndrome
  76. Dextran Removal by Plasmapheresis in a Kidney-Pancreas Transplant Recipient With Dextran 40–Induced Osmotic Nephrosis
  77. Nedd4–2 interacts with occludin to inhibit tight junction formation and enhance paracellular conductance in collecting duct epithelia
  78. Alternate processing of Flt1 transcripts is directed by conserved cis -elements within an intronic region of FLT1 that reciprocally regulates splicing and polyadenylation
  79. Unrecognized Acute Phosphate Nephropathy in a Kidney Donor with Consequent Poor Allograft Outcome
  80. A Recently Evolved Novel Trophoblast-Enriched Secreted Form of fms-Like Tyrosine Kinase-1 Variant Is Up-Regulated in Hypoxia and Preeclampsia
  81. Recurrent Atypical Hemolytic Uremic Syndrome Associated With Factor I Mutation in a Living Related Renal Transplant Recipient
  82. An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function
  83. A genetic syndrome of chronic renal failure with multiple renal cysts and early onset diabetes
  84. Nedd4-2 isoforms ubiquitinate individual epithelial sodium channel subunits and reduce surface expression and function of the epithelial sodium channel
  85. Serum/glucocorticoid-induced protein kinase-1 facilitates androgen receptor-dependent cell survival
  86. Intronic polyadenylation signal sequences and alternate splicing generate human soluble Fltl variants and regulate the abundance of soluble Flt1 in the placenta
  87. Diffuse Glomerular Crescents and Peritubular Immune Deposits in a Transplant Kidney
  88. Medroxyprogesterone acetate binds the glucocorticoid receptor to stimulate α-ENaC and sgk1 expression in renal collecting duct epithelia
  89. Nedd4–2 isoforms differentially associate with ENaC and regulate its activity
  90. Early Postnephrectomy Donor Renal Function: Laparoscopic versus Open Procedure
  91. Dual Therapeutic Utility of Proteasome Modulating Agents for Pharmaco-gene Therapy of the Cystic Fibrosis Airway
  92. cAMP-stimulated Na+transport in H441 distal lung epithelial cells: role of PKA, phosphatidylinositol 3-kinase, and sgk1
  93. AVP-induced VIT32 gene expression in collecting duct cells occurs via trans-activation of a CRE in the 5′-flanking region of the VIT32 gene
  94. New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis
  95. Transcriptional repression of the CTP:phosphocholine cytidylyltransferase gene by sphingosine
  96. Systemic Pseudohypoaldosteronism from Deletion of the Promoter Region of the HumanβEpithelial Na+Channel Subunit
  97. Lipid deprivation increases surfactant phosphatidylcholine synthesis via a sterol-sensitive regulatory element within the CTP:phosphocholine cytidylyltransferase promoter
  98. The  -Subunit of the Epithelial Sodium Channel Is an Aldosterone-Induced Transcript in Mammalian Collecting Ducts, and This Transcriptional Response Is Mediated via Distinct cis-Elements in the 5'-Flanking Region of the Gene
  99. Human amiloride-sensitive epithelial Na+ channel γ subunit promoter: functional analysis and identification of a polypurine-polypyrimidine tract with the potential for triplex DNA formation
  100. Glucocorticoid Induction of Epithelial Sodium Channel Expression in Lung and Renal Epithelia Occurs via trans-Activation of a Hormone Response Element in the 5′-Flanking Region of the Human Epithelial Sodium Channel α Subunit Gene
  101. The structure of the rat amiloride-sensitive epithelial sodium channel gamma subunit gene and functional analysis of its promoter
  102. 5′ Heterogeneity in epithelial sodium channel α-subunit mRNA leads to distinct NH2-terminal variant proteins
  103. Genomic Organization and the 5′ Flanking Region of the γ Subunit of the Human Amiloride-sensitive Epithelial Sodium Channel