All Stories

  1. Enteric pharmacokinetics of monomeric and multimeric camelid nanobody single-domain antibodies

    Article • PLoS ONE, November 2023, PLOS

    Dr. Charles B Shoemaker

  2. Probing the structure and function of the protease domain of botulinum neurotoxins using single-domain antibodies

    Article • PLoS Pathogens, January 2022, PLOS

    Dr. Charles B Shoemaker

  3. Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs)

    Article • August 2016, Protein Data Bank, Rutgers University

    Dr. Charles B Shoemaker

  4. A Tetraspecific VHH-Based Neutralizing Antibody Modifies Disease Outcome in Three Animal Models of Clostridium difficile Infection

    Article • Clinical and Vaccine Immunology, July 2016, ASM Journals

    Dr. Charles B Shoemaker

  5. Adenoviral Expression of a Bispecific VHH-Based Neutralizing Agent That Targets Protective Antigen Provides Prophylactic Protection from Anthrax in Mice

    Article • Clinical and Vaccine Immunology, January 2016, ASM Journals

    Dr. Charles B Shoemaker

  6. Mechanisms of Ricin Toxin Neutralization Revealed through Engineered Homodimeric and Heterodimeric Camelid Antibodies

    Article • Journal of Biological Chemistry, September 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Nicholas J Mantis, Dr. Charles B Shoemaker

  7. A Heterodimer of a VHH (Variable Domains of Camelid Heavy Chain-only) Antibody That Inhibits Anthrax Toxin Cell Binding Linked to a VHH Antibody That Blocks Oligomer Formation Is Highly Protective in an Anthrax Spore Challenge Model

    Article • Journal of Biological Chemistry, January 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Charles B Shoemaker

  8. 148. Variable fragment of heavy chain antibody (VHH)–based neutralizing agents (VNAs) as unconventional and versatile therapeutics for toxin-mediated diseases

    Article • Toxicon, January 2015, Elsevier

    Dr. Charles B Shoemaker

  9. Prolonged Prophylactic Protection from Botulism with a Single Adenovirus Treatment Promoting Serum Expression of a VHH-Based Antitoxin Protein

    Article • PLoS ONE, August 2014, PLOS

    Dr. Charles B Shoemaker

  10. Differential Neutralizing Activities of a Single Domain Camelid Antibody (VHH) Specific for Ricin Toxin’s Binding Subunit (RTB)

    Article • PLoS ONE, June 2014, PLOS

    Dr Nicholas J Mantis, Dr. Charles B Shoemaker

  11. Stepwise Engineering of Heterodimeric Single Domain Camelid VHH Antibodies That Passively Protect Mice from Ricin Toxin

    Article • Journal of Biological Chemistry, November 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Nicholas J Mantis, Dr. Charles B Shoemaker

  12. On the Three-Finger Protein Domain Fold and CD59-Like Proteins in Schistosoma mansoni

    Article • PLoS Neglected Tropical Diseases, October 2013, PLOS

    Dr. Charles B Shoemaker

  13. A Single VHH-Based Toxin-Neutralizing Agent and an Effector Antibody Protect Mice against Challenge with Shiga Toxins 1 and 2

    Article • Infection and Immunity, September 2013, ASM Journals

    Dr. Charles B Shoemaker

  14. Schistosoma mansoni host-exposed surface antigens characterized by sera and recombinant antibodies from schistosomiasis-resistant rats

    Article • International Journal for Parasitology, October 2010, Elsevier

    Dr. Charles B Shoemaker

  15. Suppressing Glucose Transporter Gene Expression in Schistosomes Impairs Parasite Feeding and Decreases Survival in the Mammalian Host

    Article • PLoS Pathogens, June 2010, PLOS

    Dr. Charles B Shoemaker

  16. Lipid and cationic polymer based transduction of botulinum holotoxin, or toxin protease alone, extends the target cell range and improves the efficiency of intoxication

    Article • Toxicon, February 2010, Elsevier

    Dr. Charles B Shoemaker

  17. Mucosal antibody responses in experimental hookworm infection

    Article • Parasite Immunology, May 2008, Wiley

    Dr. Charles B Shoemaker

  18. Heritable transgenesis of Parastrongyloides trichosuri: A nematode parasite of mammals

    Article • International Journal for Parasitology, April 2006, Elsevier

    Dr. Charles B Shoemaker

  19. Parastrongyloides trichosuri, a nematode parasite of mammals that is uniquely suited to genetic analysis

    Article • International Journal for Parasitology, April 2006, Elsevier

    Dr. Charles B Shoemaker

  20. Development of methods for RNA interference in the sheep gastrointestinal parasite, Trichostrongylus colubriformis

    Article • International Journal for Parasitology, August 2005, Elsevier

    Dr. Charles B Shoemaker

  21. Using RNA interference to manipulate endogenous gene expression in Schistosoma mansoni sporocysts

    Article • Molecular and Biochemical Parasitology, May 2003, Elsevier

    Dr. Charles B Shoemaker

  22. Characterization of a 35-kDa carbohydrate larval antigen (CarLA) from Trichostrongylus colubriformis; a potential target for host immunity

    Article • Parasite Immunology, February 2003, Wiley

    Dr. Charles B Shoemaker

  23. Immune rejection of Trichostrongylus colubriformis in sheep; a possible role for intestinal mucus antibody against an L3-specific surface antigen

    Article • Parasite Immunology, January 2003, Wiley

    Dr. Charles B Shoemaker

  24. Schistosoma mansoni Proteases Sm31 (Cathepsin B) and Sm32 (Legumain) Are Expressed in the Cecum and Protonephridia of Cercariae

    Article • Journal of Parasitology, October 2001, JSTOR

    Dr. Charles B Shoemaker

  25. Schistosoma mansoni Proteases Sm31 (Cathepsin B) and Sm32 (Legumain) Are Expressed in the Cecum and Protonephridia of Cercariae

    Article • Journal of Parasitology, October 2001, American Society of Parasitologists

    Dr. Charles B Shoemaker

  26. Schistosoma mansoni: Molecular Characterization of a Tegumental Ca-ATPase (SMA3)

    Article • Experimental Parasitology, August 2001, Elsevier

    Dr. Charles B Shoemaker

  27. Cloning and characterization of a muscle isoform of a Na,K-ATPase alpha subunit (SNaK1) from Schistosoma mansoni

    Article • Parasitology, March 2001, Cambridge University Press

    Dr. Charles B Shoemaker

  28. Human T- and B-Cell Responses to Schistosoma mansoni Recombinant Glyceraldehyde 3-Phosphate Dehydrogenase Correlate with Resistance to Reinfection with S. mansoni or Schistosoma haematobium after Chemotherapy

    Article • Infection and Immunity, January 2001, ASM Journals

    Dr. Charles B Shoemaker

  29. The Schistosoma mansoni host-interactive tegument forms from vesicle eruptions of a cyton network

    Article • Parasitology, January 2001, Cambridge University Press

    Dr. Charles B Shoemaker

  30. Induction cues for tegument formation during the transformation of Schistosoma mansoni cercariae

    Article • International Journal for Parasitology, April 2000, Elsevier

    Dr. Charles B Shoemaker

  31. A Divergent Member of the Transforming Growth Factor   Receptor Family from Schistosoma mansoni Is Expressed on the Parasite Surface Membrane

    Article • Journal of Biological Chemistry, May 1998, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Charles B Shoemaker

  32. T and B Cell Reactivity to a 42‐kDa Protein Is Associated with Human Resistance to Both Schistosomiasis Mansoni and Haematobium

    Article • The Journal of Infectious Diseases, May 1998, Oxford University Press (OUP)

    Dr. Charles B Shoemaker

  33. The Schistosoma mansoni epidermal growth factor receptor homologue, SER, has tyrosine kinase activity and is localized in adult muscle

    Article • Molecular and Biochemical Parasitology, December 1996, Elsevier

    Dr. Charles B Shoemaker

  34. Purification and Characterization of the Hexokinase fromSchistosoma mansoni, Expressed inEscherichia coli

    Article • Protein Expression and Purification, November 1996, Elsevier

    Dr. Charles B Shoemaker

  35. Rapid appearance and asymmetric distribution of glucose transporter SGTP4 at the apical surface of intramammalian-stage Schistosoma mansoni.

    Article • Proceedings of the National Academy of Sciences, April 1996, Proceedings of the National Academy of Sciences

    Dr. Charles B Shoemaker

  36. Immunolocalization of a Schistosoma mansoni facilitated diffusion glucose transporter to the basal, but not the apical, membranes of the surface syncytium

    Article • Parasitology, May 1995, Cambridge University Press

    Dr. Charles B Shoemaker

  37. Schistosoma mansoni Hexokinase: CDNA Cloning and Immunogenicity Studies

    Article • Experimental Parasitology, February 1995, Elsevier

    Dr. Charles B Shoemaker

  38. The Schistosoma mansoni phosphagen kinase gene contains two closely apposed transcription initiation sites and arose from a fused gene duplication

    Article • Molecular and Biochemical Parasitology, December 1994, Elsevier

    Dr. Charles B Shoemaker

  39. Two Schistosoma mansoni cDNAs encoding ATP-binding cassette (ABC) family proteins

    Article • Molecular and Biochemical Parasitology, June 1994, Elsevier

    Dr. Charles B Shoemaker

  40. Expression of Schistosoma mansoni genes involved in anaerobic and oxidative glucose metabolism during the cercaria to adult transformation

    Article • Molecular and Biochemical Parasitology, July 1993, Elsevier

    Dr. Charles B Shoemaker

  41. Characterization of the Schistosoma mansoni gene encoding the glycolytic enzyme, triosephosphate isomerase

    Article • Molecular and Biochemical Parasitology, June 1993, Elsevier

    Dr. Charles B Shoemaker

  42. Alternative splicing of the Schistosoma mansoni gene encoding a homologue of epidermal growth factor receptor

    Article • Molecular and Biochemical Parasitology, July 1992, Elsevier

    Dr. Charles B Shoemaker

  43. cDNA cloning and functional expression of the Schistosoma mansoni protective antigen triose-phosphate isomerase.

    Article • Proceedings of the National Academy of Sciences, March 1992, Proceedings of the National Academy of Sciences

    Dr. Charles B Shoemaker

  44. Paramyosin is the Schistosoma mansoni (Trematoda) homologue of antigen B from Taenia solium (Cestoda)

    Article • Molecular and Biochemical Parasitology, February 1991, Elsevier

    Dr. Charles B Shoemaker

  45. Structure of Cloned Retrovirus Circular DNAs: Implications for Virus Integration

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1981, Cold Spring Harbor Laboratory Press

    Dr. Charles B Shoemaker

  46. Structure of a cloned circular Moloney murine leukemia virus DNA molecule containing an inverted segment: implications for retrovirus integration.

    Article • Proceedings of the National Academy of Sciences, July 1980, Proceedings of the National Academy of Sciences

    Dr. Charles B Shoemaker