All Stories

  1. Coordinated epigenetic dysregulation of CNR1 and FAAH genes drives endocannabinoid system dysfunction in anorexia nervosa
  2. Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
  3. High-Fat-Diet-Induced Kidney Injury in Rats: The Role of Tart Cherry Supplementation
  4. Novel ingredients and dietary supplements: investigation of their presence among herbal extracts in the food field
  5. A Combined GLP-1/PPARa/CB1-Based Therapy to Restore theCentral and Peripheral Metabolic Dysregulation Induced by a High-Fructose High-Fat Diet
  6. Correction: Micioni Di Bonaventura et al. Brain Alterations in High Fat Diet Induced Obesity: Effects of Tart Cherry Seeds and Juice. Nutrients 2020, 12, 623
  7. Repeated binge‐like eating episodes in female rats alter adenosine A2A and dopamine D2 receptor genes regulation in the brain reward system
  8. Novel rat model of gaming disorder: assessment of social reward and sex differences in behavior and c-Fos brain activity
  9. Dysfunction of the Brown Adipose Organ in HFD-Obese Rats and Effect of Tart Cherry Supplementation
  10. Evaluating the efficacy of the selective orexin 1 receptor antagonist nivasorexant in an animal model of binge‐eating disorder
  11. Anti-Glycation Properties of Zinc-Enriched Arthrospira platensis (Spirulina) Contribute to Prevention of Metaflammation in a Diet-Induced Obese Mouse Model
  12. Administration of Linoleoylethanolamide Reduced Weight Gain, Dyslipidemia, and Inflammation Associated with High-Fat-Diet-Induced Obesity
  13. GABAergic miR-34a regulates Dorsal Raphè inhibitory transmission in response to aversive, but not rewarding, stimuli
  14. The Neuromedin U system: pharmacological implications for the treatment of obesity and binge eating behavior
  15. Targeting orexin receptors: Recent advances in the development of subtype selective or dual ligands for the treatment of neuropsychiatric disorders
  16. SYNBIO® Probiotic and Antioxidant Dietary Supplementation: Clinical Trial Evaluation of Potential Effects on Airline Flight Crew Members’ Well-Being
  17. Six-Month Synbio® Administration Affects Nutritional and Inflammatory Parameters of Older Adults Included in the PROBIOSENIOR Project
  18. Anxiety associated with palatable food withdrawal is reversed by the selective FAAH inhibitor PF ‐3845: A regional analysis of the contribution of endocannabinoid signaling machinery
  19. Involvement of miR-135a-5p Downregulation in Acute and Chronic Stress Response in the Prefrontal Cortex of Rats
  20. Endocannabinoid System Regulation in Female Rats with Recurrent Episodes of Binge Eating
  21. Impact of a probiotic diet on wellbeing of healthy senior: THE PROBIOSENIOR PROJECT
  22. A Role for Neuropeptide S in Alcohol and Cocaine Seeking
  23. Anti-Inflammatory and Antioxidant Properties of Tart Cherry Consumption in the Heart of Obese Rats
  24. Obesity-Related Brain Cholinergic System Impairment in High-Fat-Diet-Fed Rats
  25. Advances in the Development of Nonpeptide Small Molecules Targeting Ghrelin Receptor
  26. A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats
  27. Role of Nociceptin/Orphanin FQ-NOP Receptor System in the Regulation of Stress-Related Disorders
  28. Ion channels alterations in the forebrain of high-fat diet fed rats
  29. Supplementation with Lactiplantibacillus plantarum IMC 510 Modifies Microbiota Composition and Prevents Body Weight Gain Induced by Cafeteria Diet in Rats
  30. Assessing the role of ghrelin and the enzyme ghrelin O-acyltransferase (GOAT) system in food reward, food motivation, and binge eating behavior
  31. Natural Antioxidant Application on Fat Accumulation: Preclinical Evidence
  32. The Neural Network of Neuropeptide S (NPS): Implications in Food Intake and Gastrointestinal Functions
  33. Tart Cherry Juice and Seeds Affect Pro-Inflammatory Markers in Visceral Adipose Tissue of High-Fat Diet Obese Rats
  34. Cannabidiol as a Potential Treatment for Anxiety and Mood Disorders: Molecular Targets and Epigenetic Insights from Preclinical Research
  35. Recent findings leading to the discovery of selective dopamine D4 receptor ligands for the treatment of widespread diseases
  36. Serum metabolic signature of binge‐like palatable food consumption in female rats by nuclear magnetic resonance spectroscopy
  37. On the Role of Central Type-1 Cannabinoid Receptor Gene Regulation in Food Intake and Eating Behaviors
  38. The Melanocortin System behind the Dysfunctional Eating Behaviors
  39. Genetic and epigenetic architecture of Obsessive-Compulsive Disorder: in search of possible diagnostic and prognostic biomarkers
  40. Novel Highly Potent and Selective Sigma1 Receptor Antagonists Effectively Blocking the Binge Eating Episode in Female Rats
  41. Effects of Exogenous Dietary Advanced Glycation End Products on the Cross-Talk Mechanisms Linking Microbiota to Metabolic Inflammation
  42. Underlying Susceptibility to Eating Disorders and Drug Abuse: Genetic and Pharmacological Aspects of Dopamine D4 Receptors
  43. Oxytocin in the neural control of eating: At the crossroad between homeostatic and non-homeostatic signals
  44. Obesity and Age-Related Changes in the Brain of the Zucker Lepr fa/fa Rats
  45. Effects of Prunus cerasus L. Seeds and Juice on Liver Steatosis in an Animal Model of Diet-Induced Obesity
  46. Xlr4 as a new candidate gene underlying vulnerability to cocaine effects
  47. Oleoylethanolamide decreases frustration stress-induced binge-like eating in female rats: a novel potential treatment for binge eating disorder
  48. Epigenetic regulation of the cannabinoid receptor CB1 in an activity-based rat model of anorexia nervosa
  49. Cardiovascular Changes Related to Metabolic Syndrome: Evidence in Obese Zucker Rats
  50. Modulation of Pain Sensitivity by Chronic Consumption of Highly Palatable Food Followed by Abstinence: Emerging Role of Fatty Acid Amide Hydrolase
  51. Brain Alterations in High Fat Diet Induced Obesity: Effects of Tart Cherry Seeds and Juice
  52. Role of Projections between Piriform Cortex and Orbitofrontal Cortex in Relapse to Fentanyl Seeking after Palatable Food Choice-Induced Voluntary Abstinence
  53. Effects of chronic silencing of relaxin-3 production in nucleus incertus neurons on food intake, body weight, anxiety-like behaviour and limbic brain activity in female rats
  54. MALDI-Mass Spectrometry Imaging to Investigate Lipid and Bile Acid Modifications Caused by Lentil Extract Used as a Potential Hypocholesterolemic Treatment
  55. Investigation of the Role of Chirality in the Interaction with σ Receptors and Effect on Binge Eating Episode of a Potent σ1 Antagonist Analogue of Spipethiane
  56. Preclinical and Clinical Evidence for a Distinct Regulation of Mu Opioid and Type 1 Cannabinoid Receptor Genes Expression in Obesity
  57. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats
  58. N/OFQ-NOP System in Food Intake
  59. Transcriptional regulation of the endocannabinoid system in a rat model of binge-eating behavior reveals a selective modulation of the hypothalamic fatty acid amide hydrolase gene
  60. Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target
  61. Environmental stressors and alcoholism development: Focus on molecular targets and their epigenetic regulation
  62. 1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor
  63. The Anterior Insular Cortex→Central Amygdala Glutamatergic Pathway Is Critical to Relapse after Contingency Management
  64. Roles of Hospital and Territorial Pharmacists within the Italian National Healthcare Service
  65. Evaluation of the hypocholesterolemic effect and prebiotic activity of a lentil (Lens culinaris Medik) extract
  66. Hypothalamic CRF1 receptor mechanisms are not sufficient to account for binge-like palatable food consumption in female rats
  67. Role of the area postrema in the hypophagic effects of oleoylethanolamide
  68. Context-induced relapse to cocaine seeking after punishment-imposed abstinence is associated with activation of cortical and subcortical brain regions
  69. Genetic variation and epigenetic modification of the prodynorphin gene in peripheral blood cells in alcoholism
  70. Hypothalamic expression of inflammatory mediators in an animal model of binge eating
  71. Estrogenic suppression of binge-like eating elicited by cyclic food restriction and frustrative-nonreward stress in female rats
  72. Effects of [Nphe1, Arg14, Lys15] N/OFQ-NH2 (UFP-101), a potent NOP receptor antagonist, on molecular, cellular and behavioural alterations associated with chronic mild stress
  73. The replacement of the 2-methoxy substituent of N-((6,6-diphenyl-1,4-dioxan-2-yl)methyl)-2-(2-methoxyphenoxy)ethan-1-amine improves the selectivity for 5-HT1A receptor over α1-adrenoceptor and D2-like receptor subtypes
  74. Neuropeptide S differently modulates alcohol-related behaviors in alcohol-preferring and non-preferring rats
  75. Amylin receptor components and the leptin receptor are co-expressed in single rat area postrema neurons
  76. Epigenetic regulation of nociceptin/orphanin FQ and corticotropin-releasing factor system genes in frustration stress-induced binge-like palatable food consumption
  77. Regulation of hypothalamic neuropeptides gene expression in diet induced obesity resistant rats: possible targets for obesity prediction?
  78. Antagonism/Agonism Modulation to Build Novel Antihypertensives Selectively Triggering I1-Imidazoline Receptor Activation
  79. Extravirgin olive oil up-regulates CB1 tumor suppressor gene in human colon cancer cells and in rat colon via epigenetic mechanisms
  80. Inhibition of anandamide hydrolysis enhances noradrenergic and GABAergic transmission in the prefrontal cortex and basolateral amygdala of rats subjected to acute swim stress
  81. Endocannabinoid signaling and food addiction
  82. Depressive-Like Behavior Is Paired to Monoaminergic Alteration in a Murine Model of Alzheimer's Disease
  83. Role of the basolateral amygdala in mediating the effects of the fatty acid amide hydrolase inhibitor URB597 on HPA axis response to stress
  84. Role of Bed Nucleus of the Stria Terminalis Corticotrophin-Releasing Factor Receptors in Frustration Stress-Induced Binge-Like Palatable Food Consumption in Female Rats with a History of Food Restriction
  85. Functional antagonism between nociceptin/orphanin FQ and corticotropin-releasing factor in rat anxiety-related behaviors: Involvement of the serotonergic system
  86. Caloric restriction increases the sensitivity to the hyperphagic effect of nociceptin/orphanin FQ limiting its ability to reduce binge eating in female rats
  87. A2A adenosine receptor agonists reduce both high-palatability and low-palatability food intake in female rats
  88. Binge Eating in Female Rats Induced by Yo-Yo Dieting and Stress
  89. Medial Prefrontal Cortex Neuronal Activation and Synaptic Alterations after Stress-Induced Reinstatement of Palatable Food Seeking: A Study Using c-fos-GFP Transgenic Female Rats
  90. Role of Orexin-1 Receptor Mechanisms on Compulsive Food Consumption in a Model of Binge Eating in Female Rats
  91. Effect ofHypericum perforatumExtract in an Experimental Model of Binge Eating in Female Rats
  92. Effect of fenfluramine on reinstatement of food seeking in female and male rats: implications for the predictive validity of the reinstatement model
  93. Effects of A2A adenosine receptor blockade or stimulation on alcohol intake in alcohol-preferring rats
  94. Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin
  95. Effect of prazosin and guanfacine on stress-induced reinstatement of alcohol and food seeking in rats
  96. Effect of neuropeptide S receptor antagonists and partial agonists on palatable food consumption in the rat
  97. Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating
  98. Gender differences in Nociceptin/Orphanin FQ-induced food intake in strains derived from rats prone (WOKW) and resistant (Dark Agouti) to metabolic syndrome: a possible involvement of the cocaine- and amphetamine-regulated transcript system
  99. Role of Dorsal Medial Prefrontal Cortex Dopamine D1-Family Receptors in Relapse to High-Fat Food Seeking Induced by the Anxiogenic Drug Yohimbine
  100. UFP-112 a Potent and Long-Lasting Agonist Selective for the Nociceptin/Orphanin FQ Receptor
  101. Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68
  102. The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S
  103. Pre-exposure to environmental cues predictive of food availability elicits hypothalamic-pituitary-adrenal axis activation and increases operant responding for food in female rats
  104. Chronic treatment with the selective NOP receptor antagonist [Nphe1,Arg14,Lys15]N/OFQ-NH2 (UFP-101) reverses the behavioural and biochemical effects of unpredictable chronic mild stress in rats
  105. Possible common central pathway for resistin and insulin in regulating food intake
  106. Nociceptin/orphanin FQ-induced food intake and cocaine amphetamine regulated transcript gene expression in strains derived from rats prone (WOKW) and resistant (Dark Agouti) to metabolic syndrome
  107. A preclinical model of binge eating elicited by yo-yo dieting and stressful exposure to food: effect of sibutramine, fluoxetine, topiramate, and midazolam
  108. Functional antagonism between nociceptin/orphanin FQ (N/OFQ) and corticotropin-releasing factor (CRF) in the rat brain: evidence for involvement of the bed nucleus of the stria terminalis
  109. Involvement of cocaine–amphetamine regulated transcript in the differential feeding responses to nociceptin/orphanin FQ in dark agouti and Wistar Ottawa Karlsburg W rats
  110. Oxidative damage in rat erythrocyte membranes following ethanol intake: Effect of ethyl pyruvate
  111. Protective effect of ethyl pyruvate on msP rat leukocytes damaged by alcohol intake
  112. Chronic intracerebroventricular infusion of nociceptin/orphanin FQ increases food and ethanol intake in alcohol-preferring rats
  113. Anxiolytic-like effects of nociceptin/orphanin FQ in the elevated plus maze and in the conditioned defensive burying test in rats
  114. Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats