All Stories

  1. Effects of fasudil against photothrombotic stroke in genetically modified obese (ob/ob) mice
  2. Neutrophils from Alzheimer’s disease mice fail to phagocytose debris and show altered release of immune modulators with age
  3. Assessment of Phase-Dependent Alterations in Cortical Glycolytic and Mitochondrial Metabolism Following Ischemic Stroke
  4. Gastrointestinal Dysfunction and Dysbiosis in Ischemic Stroke: Opportunities for Therapeutic Intervention
  5. recAP Administration Ameliorates Sepsis Outcomes through Modulation of Gut and Liver Inflammation
  6. A Scalable Histological Method to Embed and Section Multiple Brains Simultaneously
  7. Immunometabolism In Brain Aging and Neurodegeneration: Bridging Metabolic Pathways and Immune Responses
  8. Transplantation of Exercise-Induced Extracellular Vesicles as a Promising Therapeutic Approach in Ischemic Stroke
  9. Pediatric Traumatic Brain Injury: An Update on Preclinical Models, Clinical Biomarkers, and the Implications of Cerebrovascular Dysfunction
  10. Microvascular degeneration occurs before plaque onset and progresses with age in 3xTg AD mice
  11. Mild traumatic brain injury increases vulnerability to cerebral ischemia in mice
  12. miR-146a Dysregulates Energy Metabolism During Neuroinflammation
  13. Tissue-Nonspecific Alkaline Phosphatase in Central Nervous System Health and Disease: A Focus on Brain Microvascular Endothelial Cells
  14. The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke
  15. Brain endothelial cell tissue-nonspecific alkaline phosphatase (TNAP) activity promotes maintenance of barrier integrity via the ROCK pathway
  16. Disruption of metabolic, sleep, and sensorimotor functional outcomes in a female transgenic mouse model of Alzheimer’s disease
  17. A novel role for tissue-nonspecific alkaline phosphatase at the blood-brain barrier during sepsis
  18. Intermittent Lipopolysaccharide Exposure Significantly Increases Cortical Infarct Size and Impairs Autophagy
  19. Amyloid-β Causes Mitochondrial Dysfunction via a Ca2+-Driven Upregulation of Oxidative Phosphorylation and Superoxide Production in Cerebrovascular Endothelial Cells
  20. Vascular Cellular Adhesion Molecule-1 (VCAM-1) and Memory Impairment in African-Americans after Small Vessel-Type Stroke
  21. Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis
  22. Loss of tissue-nonspecific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis
  23. The cerebral angiome: High resolution MicroCT imaging of the whole brain cerebrovasculature in female and male mice
  24. Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock
  25. Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis
  26. Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment
  27. Alkaline phosphatase: a potential biomarker for stroke and implications for treatment
  28. Estrogens as neuroprotectants: Estrogenic actions in the context of cognitive aging and brain injury
  29. MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson’s Disease Phenotype
  30. Merging Electronic Health Record Data and Genomics for Cardiovascular Research
  31. Chronic Systemic Immune Dysfunction in African-Americans with Small Vessel-Type Ischemic Stroke
  32. Arginine Deprivation and Immune Suppression in a Mouse Model of Alzheimer's Disease
  33. SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome
  34. Long-Term Effects on Cognitive Function of Postmenopausal Hormone Therapy Prescribed to Women Aged 50 to 55 Years
  35. Fueling the flame: bioenergy couples metabolism and inflammation
  36. Simultaneous Determination of 6 L-Arginine Metabolites in Human and Mouse Plasma by Using Hydrophilic-Interaction Chromatography and Electrospray Tandem Mass Spectrometry
  37. Production of Proinflammatory Cytokines and Chemokines During Neuroinflammation: Novel Roles for Estrogen Receptors α and β
  38. APOE genotype-specific differences in the innate immune response
  39. Neuroprotective effects of estrogens following ischemic stroke
  40. Estradiol Is a Potent Protective, Restorative, and Trophic Factor after Brain Injury
  41. The APOE4 genotype alters the response of microglia and macrophages to 17β-estradiol
  42. Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury
  43. Androgen-Mediated Immune Function Is Altered by the Apolipoprotein E Gene
  44. Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions
  45. Advancing the Study of Stroke in Women
  46. Characterization of NO and Cytokine Production in Immune-Activated Microglia and Peritoneal Macrophages Derived from a Mouse Model Expressing the Human NOS2 Gene on a Mouse NOS2 Knockout Background
  47. Mechanisms of Neuroprotection by Estrogen
  48. Are Estrogens Protective or Risk Factors in Brain Injury and Neurodegeneration? Reevaluation after the Women’s Health Initiative
  49. Sex steroids, APOE genotype and the innate immune system
  50. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress
  51. Apolipoprotein E isoform mediated regulation of nitric oxide release1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list o...
  52. Apolipoprotein-E Allele-Specific Regulation of Nitric Oxide Production
  53. Daily rhythms of metabolic heat production, body temperature, and locomotor activity in golden hamsters