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  1. Transplantation of Exercise-Induced Extracellular Vesicles as a Promising Therapeutic Approach in Ischemic Stroke

    Article • Translational Stroke Research, May 2022, Springer Science + Business Media

    Dr. Candice Brown

  2. Pediatric Traumatic Brain Injury: An Update on Preclinical Models, Clinical Biomarkers, and the Implications of Cerebrovascular Dysfunction

    Article • Journal of Central Nervous System Disease, January 2022, SAGE Publications

    Dr. Candice Brown

  3. Microvascular degeneration occurs before plaque onset and progresses with age in 3xTg AD mice

    Article • Neurobiology of Aging, September 2021, Elsevier

    Dr. Candice Brown

  4. Mild traumatic brain injury increases vulnerability to cerebral ischemia in mice

    Article • Experimental Neurology, August 2021, Elsevier

    Dr. Candice Brown

  5. miR-146a Dysregulates Energy Metabolism During Neuroinflammation

    Article • Journal of Neuroimmune Pharmacology, May 2021, Springer Science + Business Media

    Dr. Candice Brown

  6. Tissue-Nonspecific Alkaline Phosphatase in Central Nervous System Health and Disease: A Focus on Brain Microvascular Endothelial Cells

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Dr. Candice Brown

  7. The Mitochondrial mitoNEET Ligand NL-1 Is Protective in a Murine Model of Transient Cerebral Ischemic Stroke

    Article • Pharmaceutical Research, May 2021, Springer Science + Business Media

    Dr. Candice Brown

  8. Brain endothelial cell tissue-nonspecific alkaline phosphatase (TNAP) activity promotes maintenance of barrier integrity via the ROCK pathway

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Dr. Candice Brown

  9. Disruption of metabolic, sleep, and sensorimotor functional outcomes in a female transgenic mouse model of Alzheimer’s disease

    Article • Behavioural Brain Research, February 2021, Elsevier

    Dr. Candice Brown

  10. A novel role for tissue-nonspecific alkaline phosphatase at the blood-brain barrier during sepsis

    Article • Neural Regeneration Research, January 2021, Medknow

    Dr. Candice Brown

  11. Intermittent Lipopolysaccharide Exposure Significantly Increases Cortical Infarct Size and Impairs Autophagy

    Article • ASN NEURO, January 2021, SAGE Publications

    Dr. Candice Brown

  12. Amyloid-β Causes Mitochondrial Dysfunction via a Ca2+-Driven Upregulation of Oxidative Phosphorylation and Superoxide Production in Cerebrovascular Endothelial Cells

    Article • Journal of Alzheimer s Disease, May 2020, IOS Press

    Dr. Candice Brown

  13. Vascular Cellular Adhesion Molecule-1 (VCAM-1) and Memory Impairment in African-Americans after Small Vessel-Type Stroke

    Article • Journal of Stroke and Cerebrovascular Diseases, February 2020, Elsevier

    Dr. Candice Brown

  14. Systemic inhibition of tissue-nonspecific alkaline phosphatase alters the brain-immune axis in experimental sepsis

    Article • Scientific Reports, December 2019, Springer Science + Business Media

    Dr. Candice Brown

  15. Loss of tissue-nonspecific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

    Article • Brain Behavior and Immunity, November 2019, Elsevier

    Dr. Candice Brown

  16. The cerebral angiome: High resolution MicroCT imaging of the whole brain cerebrovasculature in female and male mice

    Article • NeuroImage, November 2019, Elsevier

    Dr. Candice Brown

  17. Circulating extracellular vesicle content reveals de novo DNA methyltransferase expression as a molecular method to predict septic shock

    Article • Journal of Extracellular Vesicles, September 2019, Taylor & Francis

    Dr. Candice Brown

  18. Loss of tissue non-specific alkaline phosphatase (TNAP) enzyme activity in cerebral microvessels is coupled to persistent neuroinflammation and behavioral deficits in late sepsis

    Article • August 2019, Cold Spring Harbor Laboratory Press

    Dr. Candice Brown

  19. Targeting the Blood-Brain Barrier to Prevent Sepsis-Associated Cognitive Impairment

    Article • Journal of Central Nervous System Disease, January 2019, SAGE Publications

    Dr. Candice Brown

  20. Alkaline phosphatase: a potential biomarker for stroke and implications for treatment

    Article • Metabolic Brain Disease, October 2018, Springer Science + Business Media

    Dr. Candice Brown

  21. Estrogens as neuroprotectants: Estrogenic actions in the context of cognitive aging and brain injury

    Article • Progress in Neurobiology, October 2017, Elsevier

    Dr. Candice Brown

  22. MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson’s Disease Phenotype

    Article • ACS Chemical Neuroscience, September 2017, American Chemical Society (ACS)

    Dr. Candice Brown

  23. Merging Electronic Health Record Data and Genomics for Cardiovascular Research

    Article • Circulation Cardiovascular Genetics, April 2016, Wolters Kluwer Health

    Dr. Candice Brown

  24. Chronic Systemic Immune Dysfunction in African-Americans with Small Vessel-Type Ischemic Stroke

    Article • Translational Stroke Research, September 2015, Springer Science + Business Media

    Dr. Candice Brown

  25. Arginine Deprivation and Immune Suppression in a Mouse Model of Alzheimer's Disease

    Article • Journal of Neuroscience, April 2015, Society for Neuroscience

    Dr. Candice Brown

  26. SIRT1 inhibition during the hypoinflammatory phenotype of sepsis enhances immunity and improves outcome

    Article • Journal of Leukocyte Biology, July 2014, Wiley

    Dr. Candice Brown

  27. Long-Term Effects on Cognitive Function of Postmenopausal Hormone Therapy Prescribed to Women Aged 50 to 55 Years

    Article • JAMA Internal Medicine, August 2013, American Medical Association (AMA)

    Dr. Candice Brown

  28. Fueling the flame: bioenergy couples metabolism and inflammation

    Article • Journal of Leukocyte Biology, May 2012, Wiley

    Dr. Candice Brown

  29. Simultaneous Determination of 6 L-Arginine Metabolites in Human and Mouse Plasma by Using Hydrophilic-Interaction Chromatography and Electrospray Tandem Mass Spectrometry

    Article • Clinical Chemistry, March 2011, AACC

    Dr. Candice Brown

  30. Production of Proinflammatory Cytokines and Chemokines During Neuroinflammation: Novel Roles for Estrogen Receptors α and β

    Article • Endocrinology, October 2010, Endocrine Society

    Dr. Candice Brown

  31. APOE genotype-specific differences in the innate immune response

    Article • Neurobiology of Aging, September 2009, Elsevier

    Dr. Candice Brown

  32. Neuroprotective effects of estrogens following ischemic stroke

    Article • Frontiers in Neuroendocrinology, July 2009, Elsevier

    Dr. Candice Brown

  33. Estradiol Is a Potent Protective, Restorative, and Trophic Factor after Brain Injury

    Article • Seminars in Reproductive Medicine, April 2009, Thieme Publishing Group

    Dr. Candice Brown

  34. The APOE4 genotype alters the response of microglia and macrophages to 17β-estradiol

    Article • Neurobiology of Aging, December 2008, Elsevier

    Dr. Candice Brown

  35. Inducible nitric oxide synthase and estradiol exhibit complementary neuroprotective roles after ischemic brain injury

    Article • Experimental Neurology, April 2008, Elsevier

    Dr. Candice Brown

  36. Androgen-Mediated Immune Function Is Altered by the Apolipoprotein E Gene

    Article • Endocrinology, July 2007, Endocrine Society

    Dr. Candice Brown

  37. Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions

    Article • Proceedings of the National Academy of Sciences, April 2007, Proceedings of the National Academy of Sciences

    Dr. Candice Brown

  38. Advancing the Study of Stroke in Women

    Article • Stroke, September 2006, Wolters Kluwer Health

    Dr. Candice Brown

  39. Characterization of NO and Cytokine Production in Immune-Activated Microglia and Peritoneal Macrophages Derived from a Mouse Model Expressing the Human NOS2 Gene on a Mouse NOS2 Knockout Background

    Article • Antioxidants & Redox Signaling, May 2006, Mary Ann Liebert Inc

    Dr. Candice Brown

  40. Mechanisms of Neuroprotection by Estrogen

    Article • Endocrine, January 2006, Springer Science + Business Media

    Dr. Candice Brown

  41. Are Estrogens Protective or Risk Factors in Brain Injury and Neurodegeneration? Reevaluation after the Women’s Health Initiative

    Article • Endocrine Reviews, May 2005, Endocrine Society

    Dr. Candice Brown

  42. Sex steroids, APOE genotype and the innate immune system

    Article • Neurobiology of Aging, March 2005, Elsevier

    Dr. Candice Brown

  43. APOE and the regulation of microglial nitric oxide production: a link between genetic risk and oxidative stress

    Article • Neurobiology of Aging, September 2002, Elsevier

    Dr. Candice Brown

  44. Apolipoprotein E isoform mediated regulation of nitric oxide release1,2 1Guest Editors: Mark A. Smith and George Perry 2This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list o...

    Article • Free Radical Biology and Medicine, June 2002, Elsevier

    Professor George Perry, Dr. Candice Brown

  45. Apolipoprotein-E Allele-Specific Regulation of Nitric Oxide Production

    Article • Annals of the New York Academy of Sciences, May 2002, Wiley

    Dr. Candice Brown

  46. Daily rhythms of metabolic heat production, body temperature, and locomotor activity in golden hamsters

    Article • Journal of Thermal Biology, August 1996, Elsevier

    Dr. Candice Brown