All Stories

  1. Unravelling the role of epigenetic priming in a model of perinatal white matter injury
  2. Delayed treatments might lead to options to improve the lives of infants who incur brain injury.
  3. Studying the immune cells of the ‘little brain’ to develop therapies for brain injury.
  4. Filling knowledge gaps in what happens inside the infant brain during a bleed
  5. miR ‐146b Protects the Perinatal Brain against Microglia‐Induced Hypomyelination
  6. Drinking agricultural groundwater during pregnancy alters offspring brain development; a mouse study
  7. Editorial: Pathomechanisms and Treatments to Protect the Preterm, Fetal Growth Restricted and Neonatal Encephalopathic Brain
  8. Novel Electrode Architecture for Subgaleal Electroencephalography: A Feasibility Study
  9. A unique cerebellar pattern of microglia activation in a mouse model of encephalopathy of prematurity
  10. Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia–ischemia
  11. Stem cells to treat brain injury in babies - can we iron out the details to get this right?
  12. Construction engineer, menace and protector: the many role for microglia in brain damage in babies.
  13. Neuroprotection offered by mesenchymal stem cells in perinatal brain injury: Role of mitochondria, inflammation, and reactive oxygen species
  14. Brain volumetry in fetuses that deliver very preterm: An MRI pilot study
  15. Midkine: The Who, What, Where, and When of a Promising Neurotrophic Therapy for Perinatal Brain Injury
  16. Perinatal IL-1β-induced inflammation suppresses Tbr2+ intermediate progenitor cell proliferation in the developing hippocampus accompanied by long-term behavioral deficits
  17. Cortical Gray Matter Injury in Encephalopathy of Prematurity: Link to Neurodevelopmental Disorders
  18. Serial blood cytokine and chemokine mRNA and microRNA over 48 h are insult specific in a piglet model of inflammation-sensitized hypoxia–ischaemia
  19. Perinatal IL-1β-induced Inflammation Suppresses Tbr2+ Intermediate Progenitor Cell Proliferation in the Developing Hippocampus accompanied by Long-Term Behavioral Deficits
  20. High-Dose Melatonin and Ethanol Excipient Combined with Therapeutic Hypothermia in a Newborn Piglet Asphyxia Model
  21. Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain
  22. Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human
  23. Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy
  24. Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury
  25. Lipopolysaccharide‐induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo
  26. Neuroprotection of the preterm brain
  27. Neuroinflammation in preterm babies and autism spectrum disorders
  28. Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury
  29. Early origins of neuropsychiatric disorders
  30. Epigenome and transcriptome landscapes highlight dual roles of proinflammatory players in a perinatal model of white matter injury
  31. The Cerebrospinal Fluid Inflammatory Response to Preterm Birth
  32. Loss of the Wnt/β-catenin pathway in microglia of the developing brain drives pro-inflammatory activation leading to white matter injury
  33. Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus
  34. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants
  35. Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury
  36. Role of microglia in a mouse model of paediatric traumatic brain injury
  37. Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain
  38. “Integrative genomics study of microglial transcriptome reveals effect of DLG4 (PSD95) on white matter in preterm infants”
  39. Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia
  40. Long-Term Neuropathological Changes Associated with Cerebral Palsy in a Nonhuman Primate Model of Hypoxic-Ischemic Encephalopathy
  41. Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury
  42. Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury
  43. Pro-epileptogenic effects of viral-like inflammation in both mature and immature brains
  44. Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain
  45. Contribution of mast cells to injury mechanisms in a mouse model of pediatric traumatic brain injury
  46. Controversies in preterm brain injury
  47. Inhaled 45–50% argon augments hypothermic brain protection in a piglet model of perinatal asphyxia
  48. Impaired oligodendrocyte maturation in preterm infants: Potential therapeutic targets
  49. Immediate remote ischemic postconditioning after hypoxia ischemia in piglets protects cerebral white matter but not grey matter
  50. Inflammation-induced sensitization of the brain in term infants
  51. Blood-brain barrier dysfunction in disorders of the developing brain
  52. The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia
  53. A Critical Review of Models of Perinatal Infection
  54. Brain Cell Death Is Reduced With Cooling by 3.5 C to 5 C but Increased With Cooling by 8.5 C in a Piglet Asphyxia Model
  55. HIP/PAP prevents excitotoxic neuronal death and promotes plasticity
  56. Revisiting thyroid hormone treatment to prevent brain damage of prematurity
  57. Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model
  58. Brain damage of the preterm infant: new insights into the role of inflammation
  59. Failure of thyroid hormone treatment to prevent inflammation-induced white matter injury in the immature brain
  60. Stem Cell Therapy for Neonatal Brain Injury
  61. Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro
  62. Bench to Cribside: the Path for Developing a Neuroprotectant
  63. Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model
  64. Conséquences cérébrales à long terme de l’inflammation périnatale
  65. Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy?
  66. Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury
  67. Effect of maternal administration of allopregnanolone before birth asphyxia on neonatal hippocampal function in the spiny mouse
  68. Molecular Mechanisms of Neonatal Brain Injury
  69. Effects of birth asphyxia on neonatal hippocampal structure and function in the spiny mouse
  70. Systemic inflammation disrupts the developmental program of white matter
  71. Systemic Stimulation of TLR2 Impairs Neonatal Mouse Brain Development
  72. Corrigendum to “Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro” [Brain Behav. Immun. 24 (2010) 776–783]
  73. Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro
  74. Behavioural Effects of Near-Term Acute Fetal Hypoxia in a Small Precocial Animal, the Spiny Mouse (Acomys cahirinus)