All Stories

  1. A novel ketogenic diet that reduces seizures and prevents liver steatosis leads to related gut microbiome changes and restores cecal short-chain fatty acid levels in the rapid kindling rat model of epileptogenesis

    Article • Gut Microbes Reports, October 2025, Taylor & Francis

    Dr. Ir. Ardy van Helvoort

  2. Characterizing gut microbial dysbiosis and exploring the effect of prebiotic fiber supplementation in patients with COPD

    Article • European Journal of Nutrition, June 2025, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  3. Nutritional modulation of skeletal muscle weakness in an experimental model of repetitive COPD exacerbations

    Article • Heliyon, April 2025, Elsevier

    Dr. Ir. Ardy van Helvoort

  4. Dietary enrichment with n-3 lc-PUFA-rich fish oil improves preclinical outcome of radiotherapy and anti-PD-L1 combination treatment

    Article • Cancer Treatment and Research Communications, January 2025, Elsevier

    Dr. Ir. Ardy van Helvoort

  5. Pea and soy fortified with leucine stimulates muscle protein synthesis comparable to whey in a murine ageing model

    Article • European Journal of Nutrition, November 2024, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  6. Tailored recommendations for infant milk formula intake results in more accurate feeding

    Article • European Journal of Pediatrics, August 2024, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  7. Prebiotic fibre mixtures counteract the manifestation of gut microbial dysbiosis induced by the chemotherapeutic 5-Fluorouracil (5-FU) in a validated in vitro model of the colon

    Article • BMC Microbiology, June 2024, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  8. A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epilepsy

    Article • Scientific Reports, May 2024, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  9. Stroke patients have lower blood levels of nutrients that are relevant for recovery: a systematic review and meta-analysis

    Article • Frontiers in Stroke, December 2023, Frontiers

    Dr. Ir. Ardy van Helvoort

  10. Experimenteel onderzoek naar een nieuwe variant van het ketogeen dieet

    Article • Epilepsie periodiek voor professionals, September 2023, Nederlandse Liga tegen Epilepsie

    Dr. Ir. Ardy van Helvoort

  11. Muscle Protein Synthesis with a Hybrid Dairy and Plant-Based Protein Blend (P4) Is Equal to Whey Protein in a Murine Ageing Model after Fasting

    Article • Nutrients, May 2023, MDPI AG

    Dr. Ir. Ardy van Helvoort

  12. A novel orthotopic mouse model replicates human lung cancer cachexia

    Article • Journal of Cachexia Sarcopenia and Muscle, April 2023, Wiley

    Dr. Ir. Ardy van Helvoort

  13. The Modulatory Effects of Fatty Acids on Cancer Progression

    Article • Biomedicines, January 2023, MDPI AG

    Dr. Ir. Ardy van Helvoort

  14. Nutrition in the prevention and management of sarcopenia - A special focus on Asian Indians

    Article • Osteoporosis and Sarcopenia, December 2022, Elsevier

    Dr. Ir. Ardy van Helvoort

  15. Effects of a nutritional intervention on impaired behavior and cognitive function in an emphysematous murine model of COPD with endotoxin-induced lung inflammation

    Article • Frontiers in Nutrition, November 2022, Frontiers

    Dr. Ir. Ardy van Helvoort

  16. Malnutrition risk and oropharyngeal dysphagia in the chronic post-stroke phase

    Article • Frontiers in Neurology, September 2022, Frontiers

    Dr. Ir. Ardy van Helvoort

  17. Effects of Cigarette Smoke on Adipose and Skeletal Muscle Tissue: In Vivo and In Vitro Studies

    Article • Cells, September 2022, MDPI AG

    Dr. Ir. Ardy van Helvoort

  18. Changes in intestinal homeostasis and immunity in a cigarette smoke- and LPS-induced murine model for COPD: the lung-gut axis

    Article • AJP Lung Cellular and Molecular Physiology, September 2022, American Physiological Society

    Dr. Ir. Ardy van Helvoort

  19. Increased exploration and hyperlocomotion in a cigarette smoke and LPS-induced murine model of COPD: linking pulmonary and systemic inflammation with the brain

    Article • AJP Lung Cellular and Molecular Physiology, September 2022, American Physiological Society

    Dr. Ir. Ardy van Helvoort

  20. Fatty Acids as a Tool to Boost Cancer Immunotherapy Efficacy

    Article • Frontiers in Nutrition, June 2022, Frontiers

    Dr. Ir. Ardy van Helvoort

  21. Effect of targeted nutrient supplementation on physical activity and health-related quality of life in COPD: study protocol for the randomised controlled NUTRECOVER trial

    Article • BMJ Open, March 2022, BMJ

    Dr. Ir. Ardy van Helvoort

  22. Intratracheal administration of solutions in mice; development and validation of an optimized method with improved efficacy, reproducibility and accuracy

    Article • Journal of Pharmacological and Toxicological Methods, March 2022, Elsevier

    Dr. Ir. Ardy van Helvoort

  23. Impaired Nutritional Condition After Stroke From the Hyperacute to the Chronic Phase: A Systematic Review and Meta-Analysis

    Article • Frontiers in Neurology, February 2022, Frontiers

    Dr. Ir. Ardy van Helvoort

  24. Gut microbiota and short‐chain fatty acid alterations in cachectic cancer patients

    Article • Journal of Cachexia Sarcopenia and Muscle, October 2021, Wiley

    Dr. Ir. Ardy van Helvoort

  25. Deep Learning Based Automated Orthotopic Lung Tumor Segmentation in Whole-Body Mouse CT-Scans

    Article • Cancers, September 2021, MDPI AG

    Dr. Ir. Ardy van Helvoort

  26. Phosphorus bioaccessibility measured in four amino acid–based  formulas using in-vitro batch digestion translates well into phosphorus bioavailability in mice

    Article • Nutrition, September 2021, Elsevier

    Dr. Ir. Ardy van Helvoort

  27. Different elemental infant formulas show equivalent phosphorus and calcium bioavailability in healthy volunteers

    Article • Nutrition Research, January 2021, Elsevier

    Dr. Ir. Ardy van Helvoort

  28. Nutritional Interventions in Cancer Cachexia: Evidence and Perspectives From Experimental Models

    Article • Frontiers in Nutrition, December 2020, Frontiers

    Dr. Ir. Ardy van Helvoort

  29. Design of the DYNAMO study: a multi-center randomized controlled trial to investigate the effect of pre-thickened oral nutritional supplements in nursing home residents with dysphagia and malnutrition (risk)

    Article • BMC Geriatrics, December 2020, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  30. Automated CT-derived skeletal muscle mass determination in lower hind limbs of mice using a 3D U-Net deep learning network

    Article • Journal of Applied Physiology, January 2020, American Physiological Society

    Dr. Ir. Ardy van Helvoort

  31. Identification of microRNAs in skeletal muscle associated with lung cancer cachexia

    Article • Journal of Cachexia Sarcopenia and Muscle, December 2019, Wiley

    Dr. Ir. Ardy van Helvoort

  32. Non-digestible oligosaccharides partially prevent the development of LPS-induced lung emphysema in mice

    Article • PharmaNutrition, December 2019, Elsevier

    Dr. Ir. Ardy van Helvoort

  33. Cowʼs Milk Allergic Infants on Elemental Formula Maintain Adequate Mineral Status Despite Using Acid-suppressive Drugs

    Article • Journal of Pediatric Gastroenterology and Nutrition, November 2019, Wolters Kluwer Health

    Dr. Ir. Ardy van Helvoort

  34. A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice

    Article • International Journal of Molecular Sciences, October 2019, MDPI AG

    Dr. Ir. Ardy van Helvoort, Professor Renger Witkamp

  35. Disease‐induced and treatment‐induced alterations in body composition in locally advanced head and neck squamous cell carcinoma

    Article • Journal of Cachexia Sarcopenia and Muscle, September 2019, Wiley

    Dr. Ir. Ardy van Helvoort

  36. Clinical outcome and cost-effectiveness of a 1-year nutritional intervention programme in COPD patients with low muscle mass: The randomized controlled NUTRAIN trial

    Article • Clinical Nutrition, March 2019, Elsevier

    Dr. Ir. Ardy van Helvoort

  37. Psychological co-morbidities in COPD: Targeting systemic inflammation, a benefit for both?

    Article • European Journal of Pharmacology, January 2019, Elsevier

    Dr. Ir. Ardy van Helvoort

  38. Regulation of muscle atrophy by microRNAs

    Article • Current Opinion in Clinical Nutrition & Metabolic Care, November 2018, Wolters Kluwer Health

    Dr. Ir. Ardy van Helvoort

  39. Low Levels of Branched Chain Amino Acids, Eicosapentaenoic Acid and Micronutrients are Associated with Low Muscle Mass, Strength and Function in Community-Dwelling Older Adults

    Article • The journal of nutrition health & aging, October 2018, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  40. Association between Oropharyngeal Dysphagia and Malnutrition in Dutch Nursing Home Residents: Results of the National Prevalence Measurement of Quality of Care

    Article • The journal of nutrition health & aging, September 2018, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  41. Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men

    Article • Clinical Nutrition, September 2018, Elsevier

    Dr. Ir. Ardy van Helvoort, Professor Renger Witkamp

  42. Reduced dietary intake of micronutrients with antioxidant properties negatively impacts muscle health in aged mice

    Article • Journal of Cachexia Sarcopenia and Muscle, October 2017, Wiley

    Dr. Ir. Ardy van Helvoort

  43. A randomized clinical trial investigating the efficacy of targeted nutrition as adjunct to exercise training in COPD

    Article • Journal of Cachexia Sarcopenia and Muscle, June 2017, Wiley

    Dr. Ir. Ardy van Helvoort

  44. Fish oil LC-PUFAs do not affect blood coagulation parameters and bleeding manifestations: Analysis of 8 clinical studies with selected patient groups on omega-3-enriched medical nutrition

    Article • Clinical Nutrition, March 2017, Elsevier

    Professor Renger Witkamp , Dr. Ir. Ardy van Helvoort

  45. Glycaemic responses to liquid food supplements among three Asian ethnic groups

    Article • European Journal of Nutrition, October 2015, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  46. Improved body weight and performance status and reduced serum PGE2levels after nutritional intervention with a specific medical food in newly diagnosed patients with esophageal cancer or adenocarcinoma of the gastro-esophageal junction

    Article • Journal of Cachexia Sarcopenia and Muscle, March 2015, Wiley

    Dr. Ir. Ardy van Helvoort

  47. Rapid EPA and DHA incorporation and reduced PGE2 levels after one week intervention with a medical food in cancer patients receiving radiotherapy, a randomized trial

    Article • Clinical Nutrition, June 2013, Elsevier

    Dr. Ir. Ardy van Helvoort

  48. Muscle protein synthesis in cancer patients can be stimulated with a specially formulated medical food

    Article • Clinical Nutrition, December 2011, Elsevier

    Dr. Ir. Ardy van Helvoort

  49. Bacterial Translocation Is Reduced by a Specific Nutritional Combination in Mice with Chemotherapy-Induced Neutropenia

    Article • Journal of Nutrition, May 2011, Oxford University Press (OUP)

    Jan Knol, Dr. Ir. Ardy van Helvoort

  50. Dose-dependent effects of leucine supplementation on preservation of muscle mass in cancer cachectic mice

    Article • Oncology Reports, April 2011, Spandidos Publications

    Dr. Ir. Ardy van Helvoort

  51. Supplementation with a Fish Oil-Enriched, High-Protein Medical Food Leads to Rapid Incorporation of EPA into White Blood Cells and Modulates Immune Responses within One Week in Healthy Men and Women

    Article • Journal of Nutrition, March 2011, Oxford University Press (OUP)

    Dr. Ir. Ardy van Helvoort

  52. Impaired immune function: An early marker for cancer cachexia

    Article • Oncology Reports, October 2009, Spandidos Publications

    Dr. Ir. Ardy van Helvoort

  53. Erratum: Dietary supplementation with a specific combination of high protein, leucine and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice

    Article • British Journal of Cancer, March 2009, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  54. Dietary supplementation with a specific combination of high protein, leucine and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice

    Article • British Journal of Cancer, March 2009, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  55. Erratum: Direct effects of doxorubicin on skeletal muscle contribute to fatigue

    Article • British Journal of Cancer, March 2009, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  56. Direct effects of doxorubicin on skeletal muscle contribute to fatigue

    Article • British Journal of Cancer, January 2009, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  57. Beneficial immune modulatory effects of a specific nutritional combination in a murine model for cancer cachexia

    Article • British Journal of Cancer, November 2008, Springer Science + Business Media

    Dr. Ir. Ardy van Helvoort

  58. Impaired immune function in an animal model for cancer cachexia

    Article • Proceedings of The Nutrition Society, May 2008, Cambridge University Press

    Dr. Ir. Ardy van Helvoort

  59. Mass-dependent decline of skeletal muscle function in cancer cachexia

    Article • Muscle & Nerve, January 2006, Wiley

    Dr Eline Marleen van der Beek, Dr. Ir. Ardy van Helvoort

  60. Randomized, Double-Blind, Placebo-Controlled Crossover Study in Men with Prostate Cancer and Rising PSA: Effectiveness of a Dietary Supplement

    Article • European Urology, December 2005, Elsevier

    Dr. Ir. Ardy van Helvoort

  61. ABC transporters in lipid transport

    Article • Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, June 2000, Elsevier

    Dr. Ir. Ardy van Helvoort

  62. MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping

    Article • Journal of Biological Chemistry, May 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr. Ir. Ardy van Helvoort

  63. Mice without phosphatidylcholine transfer protein have no defects in the secretion of phosphatidylcholine into bile or into lung airspaces

    Article • Proceedings of the National Academy of Sciences, September 1999, Proceedings of the National Academy of Sciences

    Dr. Ir. Ardy van Helvoort

  64. MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

    Article • Cell, November 1996, Elsevier

    Dr Hein Sprong, Dr. Ir. Ardy van Helvoort

  65. Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells.

    Article • Molecular Biology of the Cell, September 1996, American Society for Cell Biology (ASCB)

    Dr. Ir. Ardy van Helvoort

  66. Intracellular lipid heterogeneity caused by topology of synthesis and specificity in transport. Example: sphingolipids

    Article • FEBS Letters, August 1995, Wiley

    Dr. Ir. Ardy van Helvoort

  67. The human vasopressin-oxytocin gene family: no evidence for additional neurophysin-related genes

    Article • Molecular and Cellular Endocrinology, December 1993, Elsevier

    Dr. Ir. Ardy van Helvoort

  68. Advancement of Meiotic Resumption in Graafian Follicles Reduces Fertility in the Rat

    Article • Gynecologic and Obstetric Investigation, January 1993, Karger Publishers

    Dr. Ir. Ardy van Helvoort

  69. Characterization of carp B and T cells with monoclonal antibodies

    Article • Developmental & Comparative Immunology, January 1991, Elsevier

    Dr. Ir. Ardy van Helvoort