All Stories

  1. SCFA Receptors in Pancreatic β Cells: Novel Diabetes Targets?
  2. Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival
  3. Organised crime against the academic peer review system
  4. Identifying medical wearables and sensor technologies that deliver data on clinical endpoints
  5. An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion
  6. Experimental design and analysis and their reporting: new guidance for publication in BJP
  7. Chemokines and Bone
  8. BJCP 40th anniversary: moving forward, looking back
  9. Pharmacological Intervention at CCR1 and CCR5 as an Approach for Cancer: Help or Hindrance
  10. Identifying bias in CCR1 antagonists using radiolabeled binding, receptor internalization, β-arrestin translocation, and chemotaxis assays
  11. Modulation of PAR1 signalling by benzimidazole compounds
  12. Are we just learning the scales on the chemokine receptor pianos?
  13. CHAPTER 11. CCR1
  14. Therapeutic potential of CCR1 antagonists for multiple myeloma
  15. Antagonist minigenes identify genes regulated by parathyroid hormone through G protein-selective and G protein co-regulated mechanisms in osteoblastic cells
  16. GPCR Molecular Pharmacology and Drug Targeting. Edited by Annette Gilchrist.
  17. GPCR Molecular Pharmacology and Drug Targeting
  18. Traditional GPCR Pharmacology and Beyond
  19. The Use of Immortalized Cell Lines in GPCR Screening: The Good, Bad and Ugly.
  20. An Overview of Drug Screening Using Primary and Embryonic Stem Cells
  21. A perspective on more effective GPCR-targeted drug discovery efforts
  22. Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics
  23. Gα12/Gα13Subunits of Heterotrimeric G Proteins Mediate Parathyroid Hormone Activation of Phospholipase D in UMR-106 Osteoblastic Cells
  24. Second Annual GPCRs: From Orphan to Blockbuster
  25. G  COOH-Terminal Minigene Vectors Dissect Heterotrimeric G Protein Signaling
  26. G  COOH-Terminal Minigene Vectors Dissect Heterotrimeric G Protein Signaling
  27. Design and Use of C-Terminal Minigene Vectors for Studying Role of Heterotrimeric G Proteins
  28. A dominant negative approach for characterization of the G-proteins mediating histamine H2 receptor signaling
  29. A dominant negative approach for characterization of the G-proteins mediating histamine H2 receptor signaling
  30. G  Minigenes Expressing C-terminal Peptides Serve as Specific Inhibitors of Thrombin-mediated Endothelial Activation
  31. Structural Requirements for the Stabilization of Metarhodopsin II by the C Terminus of the   subunit of Transducin
  32. Systematic study of dominant negative Gα C-terminal minigenes delineate G protein pathways in thrombin-mediated responses of endothelial cells
  33. Endothelial Cell-Surface Gp60 Activates Vesicle Formation and Trafficking via G i -Coupled Src Kinase Signaling Pathway
  34. [26] Use of peptides-on-plasmids combinatorial library to identify high-affinity peptides that bind rhodopsin
  35. Thrombin Induces Proteinase-activated Receptor-1 Gene Expression in Endothelial Cells via Activation of Gi-linked Ras/Mitogen-activated Protein Kinase Pathway
  36. A Dominant-Negative Strategy for Studying Roles of G Proteins in Vivo
  37. Antagonists of the Receptor-G Protein Interface Block Gi-coupled Signal Transduction
  38. High Expression and Activation of MAP Kinase-activated Protein Kinase 2 in Cardiac Muscle Cells
  39. Heterotrimeric G proteins
  40. The Primary Structure of a Human Map Kinase Activated Protein Kinase 2