All Stories

  1. Objective Home-Monitoring of Physical Activity, Cardiovascular Parameters, and Sleep in Pediatric Obesity
  2. Futility of current urine salbutamol doping control
  3. Annotated guidance to the European Medicines Agency (EMA) guidelines and regulatory documents. A new series of the BJCP
  4. Reversal of mecamylamine-induced effects in healthy subjects by nicotine receptor agonists: Cognitive and (electro) physiological responses
  5. Integrating data from the IMPD/IB. A new tool for translational integration of preclinical effects.
  6. Pharmacological vs . classical approaches in the design of first in man clinical drug trials
  7. On authorship in a scientific journal
  8. Pharmacodynamic response profiles of anxiolytic and sedative drugs
  9. Novel SGLT2 inhibitor: first-in-man studies of antisense compound is associated with unexpected renal effects
  10. Organised crime against the academic peer review system
  11. The return of the prodigal son and the extraordinary development route of antibody TGN1412 - lessons for drug development and clinical pharmacology
  12. The Use of Biomarkers in Human Pharmacology (Phase I) Studies
  13. Van idee tot onderzoek
  14. Re-engineering the European Union Clinical Trials Directive
  15. Editors' pick 2009
  16. Editors' Report, November 2009
  17. How it works
  18. Sputum Induction Reduces Exhaled Nitric Oxide in Chronic Smokers and Non-Smokers.
  19. Evaluation of Two Sputum Processing Methods Applying Sensitive Detection Techniques in Allergic Asthmatics.
  20. Editors’ Report, December 2008
  21. Looking back: editors' pick of 2008
  22. Pharmacodynamics and Pharmacokinetics of the Novel Thrombopoietin Mimetic Peptide RWJ-800088 in Humans
  23. Lessons from TGN1412 – Authors' reply
  24. Establishing risk of human experimentation with drugs: lessons from TGN1412
  25. Cns Effects of Sumatriptan and Rizatriptan in Healthy Female Volunteers
  26. Planning and coordinating the study
  27. A Guide to Clinical Drug Research
  28. The study protocol
  29. Communicating clinical research
  30. Facilities and equipment
  31. Ethical considerations
  32. A comparison of the concentration-effect relationships of midazolam for EEG-derived parameters and saccadic peak velocity.
  33. Interaction study between nifedipine and recombinant tissue-type plasminogen activator in healthy subjects.
  34. A cross-over comparison of the anti-clotting effects of three low molecular weight heparins and glycosaminoglycuronan.
  35. Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.
  36. Good clinical practice: a question of balance [see comments]
  37. CNS-related performance and haemodynamics of metoprolol-Oros and propranolol after single and 3 days dosing in healthy volunteers.
  38. The bioavailability of digoxin from three oral formulations measured by a specific h.p.l.c. assay.
  39. Self-selection for personality variables among healthy volunteers.
  40. The pharmacokinetics of lamotrigine (BW430C) in healthy subjects with unconjugated hyperbilirubinaemia (Gilbert's syndrome).
  41. Rate-controlled rectal absorption enhancement of cefoxitin by co- administration of sodium salicylate or sodium octanoate in healthy volunteers.
  42. Lamotrigine (BW430C), a potential anticonvulsant. Effects on the central nervous system in comparison with phenytoin and diazepam.