All Stories

  1. Human Keratinocytes and Fibroblasts Co-Cultured on Silk Fibroin Scaffolds Exosomally Overrelease Angiogenic and Growth Factors
  2. NLRP3 Inflammasome’s Activation in Acute and Chronic Brain Diseases—An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with Respect to Other Inflammasomes
  3. Human EVI2B acts as a Janus-faced oncogene/antioncogene by differently affecting as per cancer type neoplastic cells growth and immune infiltration
  4. Engineering nano-drug biointerface to overcome biological barriers toward precision drug delivery
  5. “Other Than NLRP3” Inflammasomes: Multiple Roles in Brain Disease
  6. Adult Human Vascular Smooth Muscle Cells on 3D Silk Fibroin Nonwovens Release Exosomes Enriched in Angiogenic and Growth-Promoting Factors
  7. Electrospun Silk Fibroin Scaffolds for Tissue Regeneration: Chemical, Structural, and Toxicological Implications of the Formic Acid-Silk Fibroin Interaction
  8. Exosomes of adult human fibroblasts cultured on 3D silk fibroin nonwovens intensely stimulate neoangiogenesis
  9. Danger-Sensing/Patten Recognition Receptors and Neuroinflammation in Alzheimer’s Disease
  10. CaSR Antagonist (Calcilytic) NPS 2143 Hinders the Release of Neuroinflammatory IL-6, Soluble ICAM-1, RANTES, and MCP-2 from Aβ-Exposed Human Cortical Astrocytes
  11. Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration
  12. Three-Layered Silk Fibroin Tubular Scaffold for the Repair and Regeneration of Small Caliber Blood Vessels: From Design to in vivo Pilot Tests
  13. Family C G-Protein-Coupled Receptors in Alzheimer’s Disease and Therapeutic Implications
  14. Maladaptive remodeling of pulmonary artery root autografts after Ross procedure: A proteomic study
  15. Over Expressed TKTL1, CIP-2A, and B-MYB Proteins in Uterine Cervix Epithelium Scrapings as Potential Risk Predictive Biomarkers in HR-HPV-Infected LSIL/ASCUS Patients
  16. Studies on sporadic non-syndromic thoracic aortic aneurysms: 1. Deregulation of Jagged/Notch 1 homeostasis and selection of synthetic/secretor phenotype smooth muscle cells
  17. Studies on sporadic non-syndromic thoracic aortic aneurysms: II. Alterations of extra-cellular matrix components and focal adhesion proteins
  18. Targeting Human Astrocytes' Calcium-sensing Receptors for Treatment of Alzheimer's Disease
  19. Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes
  20. Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143—Further Implications for Alzheimer's Therapy
  21. Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease
  22. Biocompatible Silk Noil-Based Three-Dimensional Carded-Needled Nonwoven Scaffolds Guide the Engineering of Novel Skin Connective Tissue
  23. Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease
  24. Evidence for caspase-dependent programmed cell death along with repair processes in affected skeletal muscle fibres in patients with mitochondrial disorders
  25. Bcl10 crucially nucleates the pro-apoptotic complexes comprising PDK1, PKCζ and caspase-3 at the nuclear envelope of etoposide-treated human cervical carcinoma C4-I cells
  26. Preventing the Spread of Alzheimer’s Disease Neuropathology: A Role for Calcilytics?
  27. Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer′s disease progression?
  28. Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization
  29. The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes
  30. Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?
  31. Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's d...
  32. The calcium-sensing receptor: A novel Alzheimer's disease crucial target?
  33. Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study
  34. Direct screening of herbal blends for new synthetic cannabinoids by MALDI-TOF MS
  35. Leptin, Sonic Hedgehogs, and Neurogenesis- A Primary Cilium’s Taleon
  36. The Amyloid-β42 Proxy, Amyloid-β25-35, Induces Normal Human Cerebral Astrocytes to Produce Amyloid-β42
  37. A Paradigm-Changing Surprise from Dentate Gyrus Granule Cells— Cilium-Localized p75NTR May Drive Their Progenitor Cell Proliferation
  38. Is Alzheimer’s Disease at Least Partly a Ciliopathy?
  39. The p75 neurotrophin receptor is localized to primary cilia in adult murine hippocampal dentate gyrus granule cells
  40. Amyloid-β25–35, an Amyloid-β1–42 Surrogate, and Proinflammatory Cytokines Stimulate VEGF-A Secretion by Cultured, Early Passage, Normoxic Adult Human Cerebral Astrocytes
  41. Calcium-Sensing Receptor (CaSR) in Human Brains Pathophysiology: Roles in Late-Onset Alzheimers Disease (LOAD)
  42. Proteomic analysis of GTP cyclohydrolase 1 multiprotein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions
  43. Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells — A novel mechanism of action of a photodynamic tumor therapy agent
  44. De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials
  45. BH4 (tetrahydrobiopterin)-dependent activation, but not the expression, of inducible NOS (nitric oxide synthase)-2 in proinflammatory cytokine-stimulated, cultured normal human astrocytes is mediated by MEK-ERK kinases
  46. Roles of Ca2+ and the Ca2+-sensing receptor (CASR) in the expression of inducible NOS (nitric oxide synthase)-2 and its BH4 (tetrahydrobiopterin)-dependent activation in cytokine-stimulated adult human astrocytes
  47. Silk fibroin/poly(carbonate)-urethane as a substrate for cell growth: in vitro interactions with human cells
  48. Protein Kinase C-βIIIs an Apoptotic Lamin Kinase in Polyomavirus-transformed, Etoposide-treated pyF111 Rat Fibroblasts
  49. Increased Activity of the Protein Kinase C-δ Holoenzyme in the Cytoplasmic Particulate Fraction Precedes the Activation of Caspases in Polyomavirus-Transformed pyF111 Rat Fibroblasts Exposed to Calphostin C or Topoisomerase-II Inhibitors
  50. Changes in Nuclear Protein Kinase C-δ Holoenzyme, Its Catalytic Fragments, and Its Activity in Polyomavirus-Transformed pyF111 Rat Fibroblasts while Proliferating and Following Exposure to Apoptogenic Topoisomerase-II Inhibitors
  51. Cytosolic sialidase from pig brain: a ‘protein complex’ containing catalytic and protective units
  52. Human erythrocyte sialidase is linked to the plasma membrane by a glycosylphosphatidylinositol anchor and partly located on the outer surface
  53. Occurrence of sialidase activity in two distinct and highly homogeneous populations of lysosomes prepared from the brain of developing mouse
  54. Solubilization of the Membrane-Bound Sialidase from Pig Brain by Treatment with Bacterial Phosphatidylinositol Phospholipase C
  55. Silk fibroin-polyurethane scaffolds for tissue engineering