All Stories

  1. Nanosecond pulsed electric field applications rejuvenate aging endothelial cells by rescuing mitochondrial-to-nuclear retrograde communication
  2. A three-stage sequential surgical approach to a more efficient management of clinical stage 4 diabetic foot ulcers
  3. Natural gelatin / chitosan oligosaccharides / emodin eutectogels with multiple antibacterial effects for accelerated infected wound healing
  4. Precision Removal of Uneven Skin Tissue at the Micrometer Level via Focus-Corrected Femtosecond-Laser Ablation
  5. The quest for the perfect healing of human skin wounds: Promising models
  6. eIF6 modulates skin wound healing by upregulating keratin 6B
  7. Inflammasomes and Alzheimer's disease
  8. Combining antibiotic‐loaded bone cement‐based free vastus lateralis muscle‐sparing flap with split‐thickness skin grafts: A reliable strategy for reconstructing diabetic foot ulcers at non‐weight‐bearing areas
  9. Discovering skin-rejuvenating matrikines - a basic and applied Dermatology new frontier
  10. Human Keratinocytes and Fibroblasts Co-Cultured on Silk Fibroin Scaffolds Exosomally Overrelease Angiogenic and Growth Factors
  11. NLRP3 Inflammasome’s Activation in Acute and Chronic Brain Diseases—An Update on Pathogenetic Mechanisms and Therapeutic Perspectives with Respect to Other Inflammasomes
  12. Human EVI2B acts as a Janus-faced oncogene/antioncogene by differently affecting as per cancer type neoplastic cells growth and immune infiltration
  13. “Other Than NLRP3” Inflammasomes: Multiple Roles in Brain Disease
  14. Adult Human Vascular Smooth Muscle Cells on 3D Silk Fibroin Nonwovens Release Exosomes Enriched in Angiogenic and Growth-Promoting Factors
  15. Electrospun Silk Fibroin Scaffolds for Tissue Regeneration: Chemical, Structural, and Toxicological Implications of the Formic Acid-Silk Fibroin Interaction
  16. Exosomes of adult human fibroblasts cultured on 3D silk fibroin nonwovens intensely stimulate neoangiogenesis
  17. A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy
  18. Danger-Sensing/Patten Recognition Receptors and Neuroinflammation in Alzheimer’s Disease
  19. CaSR Antagonist (Calcilytic) NPS 2143 Hinders the Release of Neuroinflammatory IL-6, Soluble ICAM-1, RANTES, and MCP-2 from Aβ-Exposed Human Cortical Astrocytes
  20. Linking astrocytes' exosomes to Alzheimer pathogenesis and therapy
  21. Mesenchymal stromal cells-exosomes: a promising cell-free therapeutic tool for wound healing and cutaneous regeneration
  22. Three-Layered Silk Fibroin Tubular Scaffold for the Repair and Regeneration of Small Caliber Blood Vessels: From Design to in vivo Pilot Tests
  23. Family C G-Protein-Coupled Receptors in Alzheimer’s Disease and Therapeutic Implications
  24. Maladaptive remodeling of pulmonary artery root autografts after Ross procedure: A proteomic study
  25. IPC02. Silk Fibroin Vascular Graft: From Design to In Vitro and In Vivo Test
  26. Over Expressed TKTL1, CIP-2A, and B-MYB Proteins in Uterine Cervix Epithelium Scrapings as Potential Risk Predictive Biomarkers in HR-HPV-Infected LSIL/ASCUS Patients
  27. Studies on sporadic non-syndromic thoracic aortic aneurysms: 1. Deregulation of Jagged/Notch 1 homeostasis and selection of synthetic/secretor phenotype smooth muscle cells
  28. Studies on sporadic non-syndromic thoracic aortic aneurysms: II. Alterations of extra-cellular matrix components and focal adhesion proteins
  29. Astrocytes’ Role in Alzheimer’s Disease Neurodegeneration
  30. Targeting Human Astrocytes' Calcium-sensing Receptors for Treatment of Alzheimer's Disease
  31. Calcium-Sensing Receptor Antagonist NPS 2143 Restores Amyloid Precursor Protein Physiological Non-Amyloidogenic Processing in Aβ-Exposed Adult Human Astrocytes
  32. Amyloid β-Exposed Human Astrocytes Overproduce Phospho-Tau and Overrelease It within Exosomes, Effects Suppressed by Calcilytic NPS 2143—Further Implications for Alzheimer's Therapy
  33. Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease
  34. Biocompatible Silk Noil-Based Three-Dimensional Carded-Needled Nonwoven Scaffolds Guide the Engineering of Novel Skin Connective Tissue
  35. Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease
  36. Evidence for caspase-dependent programmed cell death along with repair processes in affected skeletal muscle fibres in patients with mitochondrial disorders
  37. Eukaryotic initiation factor 6 modulates myofibroblast differentiation at transforming growth factor- 1 transcription level via H2A.Z occupancy and Sp1 recruitment
  38. Bcl10 crucially nucleates the pro-apoptotic complexes comprising PDK1, PKCζ and caspase-3 at the nuclear envelope of etoposide-treated human cervical carcinoma C4-I cells
  39. The Possible Roles of the Dentate Granule Cell’s Leptin and Other Ciliary Receptors in Alzheimer’s Neuropathology
  40. Preventing the Spread of Alzheimer’s Disease Neuropathology: A Role for Calcilytics?
  41. Antagonizing amyloid-β/calcium-sensing receptor signaling in human astrocytes and neurons: a key to halt Alzheimer′s disease progression?
  42. Calcium-Sensing Receptors of Human Astrocyte-Neuron Teams: Amyloid-β-Driven Mediators and Therapeutic Targets of Alzheimer’s Disease
  43. Combining immunofluorescence with in situ proximity ligation assay: a novel imaging approach to monitor protein–protein interactions in relation to subcellular localization
  44. The Aβ Peptides-Activated Calcium-Sensing Receptor Stimulates the Production and Secretion of Vascular Endothelial Growth Factor-A by Normoxic Adult Human Cortical Astrocytes
  45. Do Astrocytes Collaborate with Neurons in Spreading the “Infectious” Aβ and Tau Drivers of Alzheimer’s Disease?
  46. Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25–35 in human cortical astrocytes and neurons—Therapeutic relevance to Alzheimer's d...
  47. The calcium-sensing receptor: A novel Alzheimer's disease crucial target?
  48. Reduction of the immunostainable length of the hippocampal dentate granule cells’ primary cilia in 3xAD-transgenic mice producing human Aβ1-42 and tau
  49. Role-Shifting PKCζ Fosters Its Own Proapoptotic Destruction by Complexing with Bcl10 at the Nuclear Envelope of Human Cervical Carcinoma Cells: A Proteomic and Biochemical Study
  50. Astrocytes may drive a Beta-Amyloid contagion in human Alzheimer's disease brains
  51. Hippocampal Membrane-Associated p75NTR Levels are Increased in Alzheimer's Disease
  52. A stable panel comprising 18 urinary proteins in the human healthy population
  53. Direct screening of herbal blends for new synthetic cannabinoids by MALDI-TOF MS
  54. Leptin, Sonic Hedgehogs, and Neurogenesis- A Primary Cilium’s Taleon
  55. The Amyloid-β42 Proxy, Amyloid-β25-35, Induces Normal Human Cerebral Astrocytes to Produce Amyloid-β42
  56. A Paradigm-Changing Surprise from Dentate Gyrus Granule Cells— Cilium-Localized p75NTR May Drive Their Progenitor Cell Proliferation
  57. Is Alzheimer’s Disease at Least Partly a Ciliopathy?
  58. The p75 neurotrophin receptor is localized to primary cilia in adult murine hippocampal dentate gyrus granule cells
  59. Amyloid-β25–35, an Amyloid-β1–42 Surrogate, and Proinflammatory Cytokines Stimulate VEGF-A Secretion by Cultured, Early Passage, Normoxic Adult Human Cerebral Astrocytes
  60. Calphostin C, a remarkable multimodal photodynamic killer of neoplastic cells by selective nuclear lamin B1 destruction and apoptogenesis (Review)
  61. Calcium-Sensing Receptor (CaSR) in Human Brains Pathophysiology: Roles in Late-Onset Alzheimers Disease (LOAD)
  62. Proteomic analysis of GTP cyclohydrolase 1 multiprotein complexes in cultured normal adult human astrocytes under both basal and cytokine-activated conditions
  63. Photoexcited calphostin C selectively destroys nuclear lamin B1 in neoplastic human and rat cells — A novel mechanism of action of a photodynamic tumor therapy agent
  64. Comano's (Trentino) thermal water interferes with tumour necrosis factor-α expression and interleukin-8 production and secretion by cultured human psoriatic keratinocytes: Yet other mechanisms of its anti-psoriatic action
  65. Comano's (Trentino) thermal water interferes with interleukin-6 production and secretion and with cytokeratin-16 expression by cultured human psoriatic keratinocytes: Further potential mechanisms of its anti-psoriatic action
  66. Novel dermo-epidermal equivalents on silk fibroin-based formic acid-crosslinked three-dimensional nonwoven devices with prospective applications in human tissue engineering/regeneration/repair
  67. Comano's (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: A potential mechanism of its anti-psoriatic action
  68. De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials
  69. BH4 (tetrahydrobiopterin)-dependent activation, but not the expression, of inducible NOS (nitric oxide synthase)-2 in proinflammatory cytokine-stimulated, cultured normal human astrocytes is mediated by MEK-ERK kinases
  70. Roles of Ca2+ and the Ca2+-sensing receptor (CASR) in the expression of inducible NOS (nitric oxide synthase)-2 and its BH4 (tetrahydrobiopterin)-dependent activation in cytokine-stimulated adult human astrocytes
  71. Expression of protein kinase C isoforms and interleukin-1  in myofibrillar myopathy
  72. Silk Fibroin-Coated Three-Dimensional Polyurethane Scaffolds for Tissue Engineering: Interactions with Normal Human Fibroblasts
  73. Silk fibroin/poly(carbonate)-urethane as a substrate for cell growth: in vitro interactions with human cells
  74. Role of p75 Neurotrophin Receptor in the Neurotoxicity by β-amyloid Peptides and Synergistic Effect of Inflammatory Cytokines
  75. Protein Kinase C-βIIIs an Apoptotic Lamin Kinase in Polyomavirus-transformed, Etoposide-treated pyF111 Rat Fibroblasts
  76. Neurotrophin p75 Receptor Is Involved in Neuronal Damage by Prion Peptide-(106–126)
  77. Increased Activity of the Protein Kinase C-δ Holoenzyme in the Cytoplasmic Particulate Fraction Precedes the Activation of Caspases in Polyomavirus-Transformed pyF111 Rat Fibroblasts Exposed to Calphostin C or Topoisomerase-II Inhibitors
  78. β-Amyloid Activates the O⨪2Forming NADPH Oxidase in Microglia, Monocytes, and Neutrophils
  79. Changes in Nuclear Protein Kinase C-δ Holoenzyme, Its Catalytic Fragments, and Its Activity in Polyomavirus-Transformed pyF111 Rat Fibroblasts while Proliferating and Following Exposure to Apoptogenic Topoisomerase-II Inhibitors
  80. Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures
  81. Silk fibroin-polyurethane scaffolds for tissue engineering