All Stories

  1. Benzoylthioureas: Design, Synthesis and Antimycobacterial Evaluation
  2. Synthesis and Antimicrobial Activity of Thiohydantoins Obtained from L-Amino Acids
  3. Activities of 2-phthalimidethanol and 2-phthalimidethyl nitrate, phthalimide analogs devoid of the glutarimide moiety, in experimental models of inflammatory pain and edema
  4. Synthesis, antinociceptive activity and pharmacokinetic profiles of nicorandil and its isomers
  5. Editorial (Thematic Issue: Plant Natural Products: Inspiring Sources for Drugs Development)
  6. From Nature to Market: Examples of Natural Products that Became Drugs
  7. Efficient synthesis of 2,4-disubstituted quinolines: calix[n]arene-catalyzed Povarov-hydrogen-transfer reaction cascade
  8. Calixarene Catalyze Cascade Povarov−Hydrogen-Transfer Reaction in Synthesis of Quinolines
  9. Calix[6]arene bypasses human pancreatic cancer aggressiveness: Downregulation of receptor tyrosine kinases and induction of cell death by reticulum stress and autophagy
  10. β-Cyclodextrin-assisted synthesis of Biginelli adducts under solvent-free conditions
  11. Calix[n]arenes as Goldmines for the Development of Chemical Entities of Pharmaceutical Interest
  12. In vivo wound healing and antiulcer properties of white sweet potato (Ipomoea batatas)
  13. Biological Activities of Eco-Friendly Synthesized Hantzsch Adducts
  14. 3-Benzoyl-1-[4-(methylsulfanyl)phenyl]thiourea
  15. Activity of nicorandil, a nicotinamide derivative with a nitrate group, in the experimental model of pain induced by formaldehyde in mice
  16. rac-5-(1-Methylethyl)-2-sulfanylideneimidazolidin-4-one
  17. Design of New Drugs for the Treatment of Alzheimer's Disease Based on Tacrine Structure
  18. Organocatalysis in the three-component Povarov reaction and investigation by mass spectrometry
  19. Synthesis, kinetic studies and molecular modeling of novel tacrine dimers as cholinesterase inhibitors
  20. Design of New Drugs for the Treatment of Alzheimer’s Disease Based on Tacrine Structure
  21. Seek and Destroy: The Use of Natural Compounds for Targeting the Molecular Roots of Cancer
  22. Calix[n]arenes in Action: Useful Host-Guest Catalysis in Organic Chemistry
  23. Free radical scavenging and antiproliferative properties of Biginelli adducts
  24. Synthesis and Anti-Paracoccidioides Activity of Calix[n]arenes
  25. p-Sulfonic acid calixarenes as efficient and reusable organocatalysts for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones/-thiones
  26. N-acryloxysuccinimide: Synthesis, characterization, and incorporation in dental adhesives
  27. N-(2-Nitrooxyethyl)picolinamide
  28. Synthesis of Aryl Aldimines and Their Activity against Fungi of Clinical Interest
  29. Schiff bases: A short review of their antimicrobial activities
  30. Synthesis, antiproliferative activity in cancer cells and theoretical studies of novel 6α,7β-dihydroxyvouacapan-17β-oic acid Mannich base derivatives
  31. Calixarenes as New Platforms for Drug Design
  32. Effect of 6α,7β-dihydroxyvouacapan-17β-oic acid and its lactone derivatives on the growth of human cancer cells
  33. Asymmetric total synthesis and antiproliferative activity of goniothalamin oxide isomers
  34. Cytotoxicity of goniothalamin enantiomers in renal cancer cells: Involvement of nitric oxide, apoptosis and autophagy
  35. Curcumin Conjugates and Metallocomplexes as Lead Compounds for Development of Anticancer Agents - A Short Review
  36. Wound Healing Agents: The Role of Natural and Non-Natural Products in Drug Development
  37. Glutationa e enzimas relacionadas: papel biológico e importância em processos patológicos
  38. Antifungal Activity of Goniothalamin Enantiomers
  39. Alilação e crotilação catalítica e enantiosseletiva de aldeídos
  40. Trypanocidal activity of 5,6-dihydropyran-2-ones against free trypomastigotes forms of Trypanosoma cruzi
  41. Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues
  42. Cytotoxic activity of (S)-goniothalamin and analogues against human cancer cells
  43. A concise total synthesis of (R)-fluoxetine, a potent and selective serotonin reuptake inhibitor
  44. (R)-Goniothalamin: total syntheses and cytotoxic activity against cancer cell lines
  45. Ácidos siálicos: da compreensão do seu envolvimento em processos biológicos ao desenvolvimento de fármacos contra o agente etiológico da gripe
  46. Synthetic Applications of Stryker’s Reagent
  47. Asymmetric reduction of prochiral ketones using in situ generated oxazaborolidine derived from (1S,2S,3R,4R)-3-amino-7,7-dimethoxynorbornan-2-ol. An efficient synthesis of enantiopure (R)-tomoxetine
  48. Enantioselective syntheses of (R)- and (S)-argentilactone and their cytotoxic activities against cancer cell lines
  49. Total Syntheses of (R)‐Argentilactone (IV) and (R)‐Goniothalamin (VII) via Catalytic Enantioselective Allylation of Aldehydes.
  50. Total syntheses of (R)-argentilactone and (R)-goniothalamin via catalytic enantioselective allylation of aldehydes
  51. Enantioselective approach to the asymmetric synthesis of (6R)-hydroxymethyl-5,6-dihydro-2H-pyran-2-one. A formal synthesis of (R)-argentilactone and total synthesis of (R)-goniothalamin