All Stories

  1. Mesoporous silica-based nanocomposite surfaces with ROS-generating copper phosphonate functional groups in the fight against dangerous microorganisms

    Article • Applied Surface Science, November 2025, Elsevier

    Andrzej Stepulak

  2. A Patient-Derived Scaffold-Based 3D Culture Platform for Head and Neck Cancer: Preserving Tumor Heterogeneity for Personalized Drug Testing

    Article • August 2025, Cold Spring Harbor Laboratory Press

    Andrzej Stepulak

  3. Analysis of Antifungal Drug Resistance Among Candida Spp. and Other Pathogenic Yeasts Isolated from Patients in Eastern Poland: Diagnostic Problems [Corrigendum]

    Article • Infection and Drug Resistance, May 2025, Taylor & Francis

    Andrzej Stepulak

  4. Advancing Head and Neck Cancer Therapies: From Conventional Treatments to Emerging Strategies

    Article • Biomedicines, April 2025, MDPI AG

    Andrzej Stepulak

  5. Analysis of Antifungal Drug Resistance Among Candida Spp. and Other Pathogenic Yeasts Isolated from Patients in Eastern Poland: Diagnostic Problems

    Article • Infection and Drug Resistance, April 2025, Taylor & Francis

    Andrzej Stepulak

  6. Triple-Negative Breast Cancer Progression and Drug Resistance in the Context of Epithelial–Mesenchymal Transition

    Article • Cancers, January 2025, MDPI AG

    Andrzej Stepulak

  7. Acetylation of Histone H3 in Cancer Progression and Prognosis

    Article • International Journal of Molecular Sciences, October 2024, MDPI AG

    Andrzej Stepulak

  8. Transcription Factors and Markers Related to Epithelial–Mesenchymal Transition and Their Role in Resistance to Therapies in Head and Neck Cancers

    Article • Cancers, March 2024, MDPI AG

    Andrzej Stepulak

  9. Cooperativity of ESPT and Aggregation-Induced Emission Effects—An Experimental and Theoretical Analysis of a 1,3,4-Thiadiazole Derivative

    Article • International Journal of Molecular Sciences, March 2024, MDPI AG

    Andrzej Stepulak

  10. Enhancing Immune Response in Non-Small-Cell Lung Cancer Patients: Impact of the 13-Valent Pneumococcal Conjugate Vaccine

    Article • Journal of Clinical Medicine, March 2024, MDPI AG

    Andrzej Stepulak

  11. The Role of Sirtuin 6 in the Deacetylation of Histone Proteins as a Factor in the Progression of Neoplastic Disease

    Article • International Journal of Molecular Sciences, December 2023, MDPI AG

    Andrzej Stepulak

  12. Emodin-8-O-Glucoside—Isolation and the Screening of the Anticancer Potential against the Nervous System Tumors

    Article • Molecules, October 2023, MDPI AG

    Andrzej Stepulak

  13. Heterogeneous Cellular Response of Primary and Metastatic Human Gastric Adenocarcinoma Cell Lines to Magnoflorine and Its Additive Interaction with Docetaxel

    Article • International Journal of Molecular Sciences, October 2023, MDPI AG

    Andrzej Stepulak

  14. Estrogen Receptor Signaling in Breast Cancer

    Article • Cancers, September 2023, MDPI AG

    Andrzej Stepulak

  15. Kaiso Protein Expression Correlates with Overall Survival in TNBC Patients

    Article • Journal of Clinical Medicine, January 2023, MDPI AG

    Andrzej Stepulak

  16. Dexmedetomidine Increases MMP-12 and MBP Concentrations after Coronary Artery Bypass Graft Surgery with Extracorporeal Circulation Anaesthesia without Impacting Cognitive Function: A Randomised Control Trial

    Article • International Journal of Environmental Research and Public Health, December 2022, MDPI AG

    Andrzej Stepulak

  17. Zingiber officinale Rosc. in the Treatment of Metabolic Syndrome Disorders—A Review of In Vivo Studies

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Andrzej Stepulak

  18. Effect of Antibiotic Amphotericin B Combinations with Selected 1,3,4-Thiadiazole Derivatives on RPTECs in an In Vitro Model

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Andrzej Stepulak

  19. Isoquinoline Alkaloids from Coptis chinensis Franch: Focus on Coptisine as a Potential Therapeutic Candidate against Gastric Cancer Cells

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Andrzej Stepulak

  20. Antagonistic Pharmacological Interaction between Sirtuin Inhibitor Cambinol and Paclitaxel in Triple-Negative Breast Cancer Cell Lines: An Isobolographic Analysis

    Article • International Journal of Molecular Sciences, June 2022, MDPI AG

    Andrzej Stepulak

  21. Assessment of Pharmacological Interactions between SIRT2 Inhibitor AGK2 and Paclitaxel in Different Molecular Subtypes of Breast Cancer Cells

    Article • Cells, April 2022, MDPI AG

    Andrzej Stepulak

  22. Acetylenic Synthetic Betulin Derivatives Inhibit Akt and Erk Kinases Activity, Trigger Apoptosis and Suppress Proliferation of Neuroblastoma and Rhabdomyosarcoma Cell Lines

    Article • International Journal of Molecular Sciences, November 2021, MDPI AG

    Andrzej Stepulak

  23. Antagonistic Interaction between Histone Deacetylase Inhibitor: Cambinol and Cisplatin—An Isobolographic Analysis in Breast Cancer In Vitro Models

    Article • International Journal of Molecular Sciences, August 2021, MDPI AG

    Andrzej Stepulak

  24. Valproic Acid and Breast Cancer: State of the Art in 2021

    Article • Cancers, July 2021, MDPI AG

    Andrzej Stepulak

  25. Xanthohumol Impairs the PMA-Driven Invasive Behaviour of Lung Cancer Cell Line A549 and Exerts Anti-EMT Action

    Article • Cells, June 2021, MDPI AG

    Andrzej Stepulak

  26. Sensitization of MCF7 Cells with High Notch1 Activity by Cisplatin and Histone Deacetylase Inhibitors Applied Together

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Andrzej Stepulak

  27. Epidermal Growth Factor Receptor and its OncogenicEGFRvIIIVariant in Benign and Malignant Brain Tumors

    Article • Anticancer Research, January 2021, International Institute of Anticancer Research

    Andrzej Stepulak

  28. Towards an evaluation of alcoholic liver cirrhosis and nonalcoholic fatty liver disease patients with hematological scales

    Article • World Journal of Gastroenterology, December 2020, Baishideng Publishing Group Co., Limited (formerly WJG Press)

    Andrzej Stepulak

  29. Magnoflorine—Isolation and the Anticancer Potential against NCI-H1299 Lung, MDA-MB-468 Breast, T98G Glioma, and TE671 Rhabdomyosarcoma Cancer Cells

    Article • Biomolecules, November 2020, MDPI AG

    Andrzej Stepulak

  30. Synthetic Betulin Derivatives Inhibit Growth of Glioma CellsIn Vitro

    Article • Anticancer Research, October 2020, International Institute of Anticancer Research

    Andrzej Stepulak

  31. Imperatorin as a Promising Chemotherapeutic Agent against Human Larynx Cancer and Rhabdomyosarcoma Cells

    Article • Molecules, April 2020, MDPI AG

    Andrzej Stepulak

  32. Synergistic or Additive Pharmacological Interactions between Magnoflorine and Cisplatin in Human Cancer Cells of Different Histological Origin

    Article • International Journal of Molecular Sciences, April 2020, MDPI AG

    Andrzej Stepulak

  33. Prostate and breast cancer cells death induced by xanthohumol investigated with Fourier transform infrared spectroscopy

    Article • Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, April 2020, Elsevier

    Andrzej Stepulak

  34. Advances in Chemistry and Bioactivity of Magnoflorine and Magnoflorine-Containing Extracts

    Article • International Journal of Molecular Sciences, February 2020, MDPI AG

    Andrzej Stepulak

  35. Synthetic analogues of 2-oxo acids discriminate metabolic contribution of the 2-oxoglutarate and 2-oxoadipate dehydrogenases in mammalian cells and tissues

    Article • Scientific Reports, February 2020, Springer Science + Business Media

    Andrzej Stepulak

  36. Elevated miRNA Inversely Correlates with E-cadherin Gene Expression in Tissue Biopsies from Crohn Disease Patients in contrast to Ulcerative Colitis Patients

    Article • BioMed Research International, January 2020, Wiley

    Andrzej Stepulak

  37. Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, November 2019, Elsevier

    Andrzej Stepulak

  38. Genetical engineered lung cancer cell for analyzing Epithelial-Mesenchymal transition

    Article • September 2019, Cold Spring Harbor Laboratory Press

    Andrzej Stepulak

  39. Histone deacetylase inhibitors reinforce the phenotypical markers of breast epithelial or mesenchymal cancer cells but inhibit their migratory properties

    Article • Cancer Management and Research, September 2019, Taylor & Francis

    Andrzej Stepulak

  40. Additive Pharmacological Interaction between Cisplatin (CDDP) and Histone Deacetylase Inhibitors (HDIs) in MDA-MB-231 Triple Negative Breast Cancer (TNBC) Cells with Altered Notch1 Activity—An Isobolographic Analysis

    Article • International Journal of Molecular Sciences, July 2019, MDPI AG

    Andrzej Stepulak

  41. MMP-9 and MMP-2 regulation in patients undergoing non-oncological and non-vascular elective surgery independent of the use of propofol or sevoflurane

    Article • Pharmacological Reports, June 2019, Elsevier

    Andrzej Stepulak

  42. H3K18Ac as a Marker of Cancer Progression and Potential Target of Anti-Cancer Therapy

    Article • Cells, May 2019, MDPI AG

    Andrzej Stepulak

  43. Role of N-terminus in function and dynamics of sirtuin 7: an in silico study

    Article • Journal of Biomolecular Structure and Dynamics, April 2019, Taylor & Francis

    prof. dr hab. Dariusz Matosiuk, Andrzej Stepulak

  44. MMP-2 mRNA Expression in Ovarian Cancer Tissues Predicts Patients' Response to Platinum-Taxane Chemotherapy

    Article • Anticancer Research, April 2019, International Institute of Anticancer Research

    Andrzej Stepulak

  45. Histone Deacetylase Inhibitors and Phenotypical Transformation of Cancer Cells

    Article • Cancers, January 2019, MDPI AG

    Andrzej Stepulak

  46. T-Lymphocyte Activation Is Correlated With the Presence of Anti-EBV in Patients With Laryngeal Squamous Cell Carcinoma

    Article • In Vivo, January 2019, International Institute of Anticancer Research

    Andrzej Stepulak

  47. AMPA Receptor Antagonist CFM-2 Decreases Survivin Expression in Cancer Cells

    Article • Anti-Cancer Agents in Medicinal Chemistry, July 2018, Bentham Science Publishers

    Andrzej Stepulak

  48. Riluzole Inhibits Proliferation, Migration and Cell Cycle Progression and Induces Apoptosis in Tumor Cells of Various Origins

    Article • Anti-Cancer Agents in Medicinal Chemistry, July 2018, Bentham Science Publishers

    Marta Lemieszek, Andrzej Stepulak

  49. Mapping of the three-dimensional lymphatic microvasculature in bladder tumours using light-sheet microscopy

    Article • British Journal of Cancer, March 2018, Springer Science + Business Media

    Andrzej Stepulak

  50. Light-inducible systems can aid the speed and accuracy in drug discovery

    Article • Expert Opinion on Drug Discovery, February 2018, Taylor & Francis

    Professor Adolfo Rivero-Muller, Andrzej Stepulak

  51. Superior anticancer activity is demonstrated by total extract ofCurcuma longaL. as opposed to individual curcuminoids separated by centrifugal partition chromatography

    Article • Phytotherapy Research, January 2018, Wiley

    Andrzej Stepulak

  52. Combination of Osthole and Cisplatin Against Rhabdomyosarcoma TE671 Cells Yielded Additive Pharmacologic Interaction by Means of Isobolographic Analysis

    Article • Anticancer Research, January 2018, International Institute of Anticancer Research

    Andrzej Stepulak

  53. Factors influencing P terminal force in lead V1 of the ECG in hemodialysis patients

    Article • Archives of Medical Science, January 2018, Termedia Sp. z.o.o.

    Andrzej Stepulak

  54. Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

    Article • Nature Biomedical Engineering, October 2017, Springer Science + Business Media

    Andrzej Stepulak

  55. Analysis of NPM1 splice variants reveals differential expression patterns of prognostic value in acute myeloid leukemia

    Article • Oncotarget, August 2017, Impact Journals, LLC

    Andrzej Stepulak

  56. Cyclooxygenase-2 Inhibition Enhances Proliferation of NKT Cells Derived from Patients with Laryngeal Cancer

    Article • Anticancer Research, July 2017, International Institute of Anticancer Research

    Andrzej Stepulak

  57. Additive Interaction of Cisplatin and Histone Deacetylase Inhibitors Combined Treatment in Rhabdomyosarcoma Cells – Αn Isobolographic Analysis

    Article • Anticancer Research, March 2017, International Institute of Anticancer Research

    Andrzej Stepulak

  58. How to Train a Cell–Cutting-Edge Molecular Tools

    Article • Frontiers in Chemistry, March 2017, Frontiers

    Professor Adolfo Rivero-Muller, Andrzej Stepulak

  59. Histone Deacetylase Inhibitor SAHA as Potential Targeted Therapy Agent for Larynx Cancer Cells

    Article • Journal of Cancer, January 2017, Ivyspring International Publisher

    Andrzej Stepulak

  60. Serum microtubule associated protein tau and myelin basic protein as the potential markers of brain ischaemia-reperfusion injury in patients undergoing carotid endarterectomy

    Article • Acta Angiologica, December 2016, VM Media SP. zo.o VM Group SK

    Andrzej Stepulak

  61. Serum glial fibrillary acidic protein as a marker of brain damage in patients after carotid endarterectomy

    Article • Acta Angiologica, September 2016, VM Media SP. zo.o VM Group SK

    Dr Stanislaw Przywara, Andrzej Stepulak

  62. Inhibition of mitochondrial 2-oxoglutarate dehydrogenase impairs viability of cancer cells in a cell-specific metabolism-dependent manner

    Article • Oncotarget, May 2016, Impact Journals, LLC

    Prof Victoria I Bunik, Andrzej Stepulak

  63. Xanthohumol inhibits the extracellular signal regulated kinase (ERK) signalling pathway and suppresses cell growth of lung adenocarcinoma cells

    Article • Toxicology, May 2016, Elsevier

    Andrzej Stepulak

  64. Effect of carotid endarterectomy on brain damage markers

    Article • Acta Neurologica Scandinavica, April 2016, Wiley

    Dr Stanislaw Przywara, Andrzej Stepulak

  65. A quick, one-step method for mutagenesis (additons, deletions or substitutions)

    Article • Scientific Reports, January 2016, Nature

    Professor Adolfo Rivero-Muller, Andrzej Stepulak

  66. Assessment of Interactions between Cisplatin and Two Histone Deacetylase Inhibitors in MCF7, T47D and MDA-MB-231 Human Breast Cancer Cell Lines – An Isobolographic Analysis

    Article • PLOS One, November 2015, PLOS

    Andrzej Stepulak

  67. Xanthohumol inhibits cell cycle progression and proliferation of larynx cancer cells in vitro

    Article • Chemico-Biological Interactions, October 2015, Elsevier

    Andrzej Stepulak

  68. Discovery of nitroaryl urea derivatives with antiproliferative properties

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, June 2015, Taylor & Francis

    Andrzej Stepulak, prof. dr hab. Dariusz Matosiuk

  69. Comprehensive Review on Betulin as a Potent Anticancer Agent

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    Professor Adolfo Rivero-Muller, Andrzej Stepulak

  70. Glutamate and its receptors in cancer

    Article • Journal of Neural Transmission, March 2014, Springer Science + Business Media

    Andrzej Stepulak

  71. MicroRNAs-Role in Lung Cancer

    Article • Disease Markers, January 2014, Hindawi Publishing Corporation

    Professor Adolfo Rivero-Muller, Andrzej Stepulak

  72. Preliminary results of prognostic significance of proliferating cell nuclear antigen expression in advanced primary larynx carcinomas and lymph node metastases

    Article • Archives of Medical Science, January 2010, Termedia Sp. z.o.o.

    Andrzej Stepulak

  73. The role of ionotropic glutamate receptors in cancer biology

    Article • Współczesna Onkologia, January 2010, Termedia Sp. z.o.o.

    Andrzej Stepulak

  74. Betulin Elicits Anti-Cancer Effects in Tumour Primary Cultures and Cell LinesIn Vitro

    Article • Basic & Clinical Pharmacology & Toxicology, October 2009, Wiley

    Andrzej Stepulak

  75. Expression of glutamate receptor subunits in human cancers

    Article • Histochemistry and Cell Biology, June 2009, Springer Science + Business Media

    Andrzej Stepulak

  76. The role of matrix metalloproteinases in infant traumatic brain injury

    Article • Neurobiology of Disease, March 2007, Elsevier

    Andrzej Stepulak

  77. Betulinic acid decreases expression of bcl-2 and cyclin D1, inhibits proliferation, migration and induces apoptosis in cancer cells

    Article • Naunyn-Schmiedeberg s Archives of Pharmacology, September 2006, Springer Science + Business Media

    Andrzej Stepulak

  78. NMDA antagonist inhibits the extracellular signal-regulated kinase pathway and suppresses cancer growth

    Article • Proceedings of the National Academy of Sciences, October 2005, Proceedings of the National Academy of Sciences

    Andrzej Stepulak

  79. Mechanisms leading to disseminated apoptosis following NMDA receptor blockade in the developing rat brain

    Article • Neurobiology of Disease, July 2004, Elsevier

    Andrzej Stepulak

  80. Reactive oxygen species production by blood neutrophils of patients with laryngeal carcinoma and antioxidative enzyme activity in their blood

    Article • Acta Oncologica, April 2004, Taylor & Francis

    Andrzej Stepulak

  81. The Intermediate Filament Protein Keratin 8 Is a Novel Cytoplasmic Substrate for c-Jun N-terminal Kinase

    Article • Journal of Biological Chemistry, January 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

    Andrzej Stepulak

  82. Tumor angiogenesis in patients with laryngeal cancer

    Article • European Archives of Oto-Rhino-Laryngology, January 1999, Springer Science + Business Media

    Andrzej Stepulak