All Stories

  1. CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond

    Article • Physiological Reviews, April 2023, American Physiological Society

    Professor Andrew F Russo

  2. Characterization of Antibodies against Receptor Activity-Modifying Protein 1 (RAMP1): A Cautionary Tale

    Article • International Journal of Molecular Sciences, December 2022, MDPI AG

    Professor Andrew F Russo

  3. Editorial: Calcitonin Gene-Related Peptide: Novel Biology and Treatments

    Article • Frontiers in Physiology, July 2022, Frontiers

    Professor Andrew F Russo

  4. CGRP and the Calcitonin Receptor are Co-Expressed in Mouse, Rat and Human Trigeminal Ganglia Neurons

    Article • Frontiers in Physiology, May 2022, Frontiers

    Professor Andrew F Russo

  5. The voltage-gated Ca2+ channel subunit α2δ-4 regulates locomotor behavior and sensorimotor gating in mice

    Article • PLOS One, March 2022, PLOS

    Professor Andrew F Russo

  6. CGRP Administration into the Cerebellum Evokes Migraine-like Behaviors Predominately in Female Mice

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Professor Andrew F Russo

  7. The voltage-gated Cav Ca2+ channel subunit α2δ-4 is required for locomotor behavior and sensorimotor gating in mice

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Professor Andrew F Russo

  8. Automated detection of squint as a sensitive assay of sex-dependent calcitonin gene–related peptide and amylin-induced pain in mice

    Article • Pain, November 2021, Wolters Kluwer Health

    Professor Andrew F Russo

  9. Investigating Migraine-Like Behavior using Light Aversion in Mice

    Article • Journal of Visualized Experiments, August 2021, MyJove Corporation

    Professor Andrew F Russo

  10. CGRP induces migraine-like symptoms in mice during both the active and inactive phases

    Article • The Journal of Headache and Pain, June 2021, Springer Science + Business Media

    Professor Andrew F Russo

  11. Hypervigilance, Allostatic Load, and Migraine Prevention: Antibodies to CGRP or Receptor

    Article • Neurology and Therapy, June 2021, Springer Science + Business Media

    Professor Andrew F Russo

  12. Female mice exhibit a more sensitive automated squint response to pain induced by CGRP and amylin

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Professor Andrew F Russo

  13. PACAP Induces Light Aversion in Mice by an Inheritable Mechanism Independent of CGRP

    Article • Journal of Neuroscience, April 2021, Society for Neuroscience

    Professor Andrew F Russo

  14. Amylin Analog Pramlintide Induces Migraine‐like Attacks in Patients

    Article • Annals of Neurology, April 2021, Wiley

    Professor Andrew F Russo

  15. Different forms of traumatic brain injuries cause different tactile hypersensitivity profiles

    Article • Pain, October 2020, Wolters Kluwer Health

    Professor Andrew F Russo

  16. A CGRP receptor antagonist peptide formulated for nasal administration to treat migraine

    Article • Journal of Pharmacy and Pharmacology, October 2020, Oxford University Press (OUP)

    Professor Andrew F Russo

  17. PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Professor Andrew F Russo

  18. Vascular actions of peripheral CGRP in migraine-like photophobia in mice

    Article • Cephalalgia, August 2020, SAGE Publications

    Professor Andrew F Russo

  19. Stimulation of Posterior Thalamic Nuclei Induces Photophobic Behavior in Mice

    Article • Headache The Journal of Head and Face Pain, August 2020, Wiley

    Professor Andrew F Russo

  20. Patients With Vestibular Migraine are More Likely to Have Occipital Headaches than those With Migraine Without Vestibular Symptoms

    Article • Headache The Journal of Head and Face Pain, July 2020, Wiley

    Professor Andrew F Russo

  21. Cross-talk signaling in the trigeminal ganglion: role of neuropeptides and other mediators

    Article • Journal of Neural Transmission, February 2020, Springer Science + Business Media

    Professor Andrew F Russo

  22. Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting

    Article • Expert Opinion on Therapeutic Targets, February 2020, Taylor & Francis

    Professor Andrew F Russo

  23. Behavioral and cognitive animal models in headache research

    Article • The Journal of Headache and Pain, January 2019, Springer Science + Business Media

    Professor Andrew F Russo

  24. CGRP-Based Migraine Therapeutics: How Might They Work, Why So Safe, and What Next?

    Article • ACS Pharmacology & Translational Science, November 2018, American Chemical Society (ACS)

    Professor Andrew F Russo

  25. Vascular Contributions to Migraine: Time to Revisit?

    Article • Frontiers in Cellular Neuroscience, August 2018, Frontiers

    Professor Andrew F Russo

  26. Current understanding of trigeminal ganglion structure and function in headache

    Article • Cephalalgia, July 2018, SAGE Publications

    Karl Messlinger, Professor Andrew F Russo

  27. Peripherally administered calcitonin gene–related peptide induces spontaneous pain in mice: implications for migraine

    Article • Pain, July 2018, Wolters Kluwer Health

    Professor Andrew F Russo

  28. Cortical spreading depression as a site of origin for migraine: Role of CGRP

    Article • Cephalalgia, April 2018, SAGE Publications

    Professor Andrew F Russo

  29. Increased receptor activity-modifying protein 1 in the nervous system is sufficient to protect against autonomic dysregulation and hypertension

    Article • Journal of Cerebral Blood Flow & Metabolism, January 2018, SAGE Publications

    Professor Andrew F Russo

  30. CGRP in Animal Models of Migraine

    Article • January 2018, Springer Science + Business Media

    Professor Andrew F Russo

  31. CGRP in the 21st century: A well-aged and blended peptide

    Article • Neuropeptides, October 2017, Elsevier

    Professor Andrew F Russo

  32. Anti-CGRP antibodies block CGRP-induced diarrhea in mice

    Article • Neuropeptides, August 2017, Elsevier

    Professor Andrew F Russo

  33. Lessons Learned from CGRP Mutant Mice

    Article • June 2017, Wiley

    Professor Andrew F Russo

  34. Overview of Neuropeptides: Awakening the Senses?

    Article • Headache The Journal of Head and Face Pain, May 2017, Wiley

    Professor Andrew F Russo

  35. CGRP receptor activity in mice with global expression of human receptor activity modifying protein 1

    Article • British Journal of Pharmacology, April 2017, Wiley

    Professor Andrew F Russo

  36. CGRP receptor antagonist activity of olcegepant depends on the signalling pathway measured

    Article • Cephalalgia, February 2017, SAGE Publications

    Dr Debbie L Hay, Professor Andrew F Russo

  37. Induction of Migraine-Like Photophobic Behavior in Mice by Both Peripheral and Central CGRP Mechanisms

    Article • Journal of Neuroscience, December 2016, Society for Neuroscience

    Professor Andrew F Russo

  38. Induction of calcitonin gene-related peptide expression in rats by cortical spreading depression

    Article • Cephalalgia, November 2016, SAGE Publications

    Professor Andrew F Russo

  39. CGRP as a neuropeptide in migraine: lessons from mice

    Article • British Journal of Clinical Pharmacology, July 2015, Wiley

    Professor Andrew F Russo

  40. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice

    Article • Journal of Clinical Investigation, May 2015, American Society for Clinical Investigation

    Professor Andrew F Russo

  41. CGRP receptors and migraine

    Article • Annals of Clinical and Translational Neurology, April 2015, Wiley

    Dr Debbie L Hay, Professor Andrew F Russo

  42. Calcitonin Gene-Related Peptide (CGRP): A New Target for Migraine

    Article • The Annual Review of Pharmacology and Toxicology, January 2015, Annual Reviews

    Professor Andrew F Russo

  43. Photophobia and Abnormally Sustained Pupil Responses in a Mouse Model of Bradyopsia

    Article • Investigative Ophthalmology & Visual Science, September 2014, Association for Research in Vision and Ophthalmology (ARVO)

    Professor Andrew F Russo

  44. Heat Hyperalgesia and Mechanical Hypersensitivity Induced by Calcitonin Gene-Related Peptide in a Mouse Model of Neurofibromatosis

    Article • PLOS One, September 2014, PLOS

    Professor Andrew F Russo

  45. Migraine meets membrane trafficking

    Article • Cephalalgia, April 2014, SAGE Publications

    Professor Andrew F Russo

  46. Reactive Oxygen Species Induce Procalcitonin Expression in Trigeminal Ganglia Glia

    Article • Headache The Journal of Head and Face Pain, February 2014, Wiley

    Professor Andrew F Russo

  47. CGRP and migraine: Could PACAP play a role too?

    Article • Neuropeptides, December 2013, Elsevier

    Professor Andrew F Russo

  48. Unanswered Questions in Headache: So What Is Photophobia, Anyway?

    Article • Headache The Journal of Head and Face Pain, September 2013, Wiley

    Professor Andrew F Russo

  49. Amylin Acts in the Central Nervous System to Increase Sympathetic Nerve Activity

    Article • Endocrinology, July 2013, Endocrine Society

    Professor Andrew F Russo

  50. Protein Inhibitors of Activated STAT (Pias1 and Piasy) Differentially Regulate Pituitary Homeobox 2 (PITX2) Transcriptional Activity

    Article • Journal of Biological Chemistry, May 2013, Elsevier

    Professor Andrew F Russo

  51. Modulation of CGRP-Induced Light Aversion in Wild-Type Mice by a 5-HT1B/DAgonist

    Article • Journal of Neuroscience, October 2012, Society for Neuroscience

    Professor Andrew F Russo

  52. Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation

    Article • Expert Reviews in Molecular Medicine, November 2011, Cambridge University Press

    Professor Andrew F Russo

  53. CGRP induction in cystic fibrosis airways alters the submucosal gland progenitor cell niche in mice

    Article • Journal of Clinical Investigation, August 2011, American Society for Clinical Investigation

    Professor Andrew F Russo

  54. Serotonin, NO, and CGRP and Headache

    Article • Headache The Journal of Head and Face Pain, June 2011, Wiley

    Professor Andrew F Russo

  55. Neuronal Receptor Activity–Modifying Protein 1 Promotes Energy Expenditure in Mice

    Article • Diabetes, March 2011, American Diabetes Association

    Professor Andrew F Russo

  56. Response to Letter by Tsuda

    Article • Stroke, February 2011, Wolters Kluwer Health

    Professor Andrew F Russo

  57. Epigenetic regulation of the calcitonin gene–related peptide gene in trigeminal glia

    Article • Cephalalgia, January 2011, SAGE Publications

    Professor Andrew F Russo

  58. Receptor Activity-Modifying Protein-1 Augments Cerebrovascular Responses to Calcitonin Gene-Related Peptide and Inhibits Angiotensin II-Induced Vascular Dysfunction

    Article • Stroke, October 2010, Wolters Kluwer Health

    Professor Andrew F Russo

  59. Receptor Activity-Modifying Protein 1 Increases Baroreflex Sensitivity and Attenuates Angiotensin-Induced Hypertension

    Article • Hypertension, March 2010, Wolters Kluwer Health

    Professor Andrew F Russo

  60. Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP

    Article • Neuropharmacology, January 2010, Elsevier

    Professor Andrew F Russo

  61. Light aversion in mice depends on nonimage-forming irradiance detection.

    Article • Behavioral Neuroscience, January 2010, American Psychological Association (APA)

    Professor Andrew F Russo

  62. Genetic Regulation of CGRP and Its Actions

    Article • September 2009, Springer Science + Business Media

    Professor Andrew F Russo

  63. Genetic Enhancement of Calcitonin Gene-Related Peptide-Induced Central Sensitization to Mechanical Stimuli in Mice

    Article • Journal of Pain, September 2009, Elsevier

    Professor Andrew F Russo

  64. Role of Calcitonin Gene-Related Peptide in Light-Aversive Behavior: Implications for Migraine

    Article • Journal of Neuroscience, July 2009, Society for Neuroscience

    Professor Andrew F Russo

  65. Calcitonin gene-related peptide: an update on the biology

    Article • Current Opinion in Neurology, June 2009, Wolters Kluwer Health

    Professor Andrew F Russo

  66. Control of the Calcitonin Gene-related Peptide Enhancer by Upstream Stimulatory Factor in Trigeminal Ganglion Neurons

    Article • Journal of Biological Chemistry, February 2008, Elsevier

    Professor Andrew F Russo

  67. Ramping it Up: RAMP1 and the Implications for Migraine

    Article • Pharmacogenomics, July 2007, Taylor & Francis

    Professor Andrew F Russo

  68. Sensitization of Calcitonin Gene-Related Peptide Receptors by Receptor Activity-Modifying Protein-1 in the Trigeminal Ganglion

    Article • Journal of Neuroscience, March 2007, Society for Neuroscience

    Professor Andrew F Russo

  69. Advent of a New Generation of Antimigraine Medications

    Article • March 2007, Wiley

    Professor Andrew F Russo

  70. CGRP receptor antagonists: A new frontier of anti-migraine medications

    Article • Drug Discovery Today Therapeutic Strategies, December 2006, Elsevier

    Professor Andrew F Russo

  71. Calcitonin Gene-Related Peptide Receptor Activation by Receptor Activity-Modifying Protein-1 Gene Transfer to Vascular Smooth Muscle Cells

    Article • Endocrinology, April 2006, Endocrine Society

    Professor Andrew F Russo

  72. Nitric oxide regulation of calcitonin gene‐related peptide gene expression in rat trigeminal ganglia neurons

    Article • European Journal of Neuroscience, April 2006, Wiley

    Professor Andrew F Russo

  73. An unusual class of PITX2 mutations in Axenfeld‐Rieger syndrome

    Article • Birth Defects Research Part A Clinical and Molecular Teratology, February 2006, Wiley

    Professor Andrew F Russo

  74. Tumor necrosis factor‐α stimulation of calcitonin gene‐related peptide expression and secretion from rat trigeminal ganglion neurons

    Article • Journal of Neurochemistry, November 2005, Wiley

    Professor Andrew F Russo

  75. Vitamin D Control of the Calcitonin Gene in Thyroid C Cells

    Article • January 2005, Elsevier

    Professor Andrew F Russo

  76. Cell-specific Activation of the Atrial Natriuretic Factor Promoter by PITX2 and MEF2A

    Article • Journal of Biological Chemistry, December 2004, Elsevier

    Professor Andrew F Russo

  77. Regulation of the Cell-specific Calcitonin/Calcitonin Gene-related Peptide Enhancer by USF and the Foxa2 Forkhead Protein

    Article • Journal of Biological Chemistry, November 2004, Elsevier

    Professor Andrew F Russo

  78. Analysis of two translocation breakpoints and identification of a negative regulatory element in patients with Rieger's syndrome

    Article • Birth Defects Research Part A Clinical and Molecular Teratology, February 2004, Wiley

    Professor Andrew F Russo

  79. Neuronal expression and regulation of CGRP promoter activity following viral gene transfer into cultured trigeminal ganglia neurons

    Article • Brain Research, January 2004, Elsevier

    Professor Andrew F Russo

  80. Dominant Negative Dimerization of a Mutant Homeodomain Protein in Axenfeld-Rieger Syndrome

    Article • Molecular and Cellular Biology, March 2003, ASM Journals

    Professor Andrew F Russo

  81. Calcium Receptor-Induced Serotonin Secretion by Parafollicular Cells: Role of Phosphatidylinositol 3-Kinase-Dependent Signal Transduction Pathways

    Article • Journal of Neuroscience, March 2003, Society for Neuroscience

    Professor Andrew F Russo

  82. Homeobox Protein, Hmx3, in Postnatally Developing Rat Submandibular Glands

    Article • Journal of Histochemistry & Cytochemistry, March 2003, SAGE Publications

    Professor Andrew F Russo

  83. Stimulation of the Calcitonin Gene-Related Peptide Enhancer by Mitogen-Activated Protein Kinases and Repression by an Antimigraine Drug in Trigeminal Ganglia Neurons

    Article • Journal of Neuroscience, February 2003, Society for Neuroscience

    Professor Andrew F Russo

  84. NCS-1 Inhibits Insulin-stimulated GLUT4 Translocation in 3T3L1 Adipocytes through a Phosphatidylinositol 4-Kinase-dependent Pathway

    Article • Journal of Biological Chemistry, July 2002, Elsevier

    Professor Andrew F Russo

  85. New insights into the molecular actions of serotonergic antimigraine drugs

    Article • Pharmacology & Therapeutics, April 2002, Elsevier

    Professor Andrew F Russo

  86. Antagonistic Regulation of <I>Dlx2</I> Expression by PITX2 and Msx2: Implications for Tooth Development

    Article • Gene Expression, June 2001, Xia & He Publishing

    Professor Andrew F Russo

  87. Autoregulation of Cell-specific MAP Kinase Control of the Tryptophan Hydroxylase Promoter

    Article • Journal of Biological Chemistry, June 2001, Elsevier

    Professor Andrew F Russo

  88. Identification of a Dominant Negative Homeodomain Mutation in Rieger Syndrome

    Article • Journal of Biological Chemistry, June 2001, Elsevier

    Professor Andrew F Russo

  89. Developmental regulation of tryptophan hydroxylase messenger RNA expression and enzyme activity in the raphe and its target fields

    Article • Neuroscience, November 2000, Elsevier

    Professor Andrew F Russo

  90. Differential Regulation of Mitogen-Activated Protein Kinase-Responsive Genes by the Duration of a Calcium Signal

    Article • Molecular Endocrinology, October 2000, Endocrine Society

    Professor Andrew F Russo

  91. Gene transfer of calcitonin gene-related peptide to cerebral arteries

    Article • AJP Heart and Circulatory Physiology, February 2000, American Physiological Society

    Professor Andrew F Russo

  92. Multifunctional Role of the Pitx2 Homeodomain Protein C-Terminal Tail

    Article • Molecular and Cellular Biology, October 1999, ASM Journals

    Professor Andrew F Russo

  93. Regulation of Calcitonin Gene-Related Peptide Secretion by a Serotonergic Antimigraine Drug

    Article • Journal of Neuroscience, May 1999, Society for Neuroscience

    Professor Andrew F Russo

  94. Transcriptional Antagonism between Hmx1 and Nkx2.5 for a Shared DNA-binding Site

    Article • Journal of Biological Chemistry, April 1999, Elsevier

    Professor Andrew F Russo

  95. The Molecular Basis of Rieger Syndrome

    Article • Journal of Biological Chemistry, August 1998, Elsevier

    Professor Andrew F Russo

  96. Serotonergic Repression of Mitogen-Activated Protein Kinase Control of the Calcitonin Gene-Related Peptide Enhancer

    Article • Molecular Endocrinology, July 1998, Endocrine Society

    Professor Andrew F Russo

  97. Measurement of tryptophan hydroxylase mRNA levels by competitive RT-PCR

    Article • Brain Research Protocols, June 1998, Elsevier

    Professor Andrew F Russo

  98. BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain

    Article • Journal of Neuroscience Research, April 1998, Wiley

    Professor Andrew F Russo

  99. Requirement of the MASH-1 transcription factor for neuroendocrine differentiation of thyroid C cells

    Article • Journal of Neurobiology, February 1998, Wiley

    Professor Andrew F Russo

  100. Repression of the Calcitonin Gene-Related Peptide Promoter by 5-HT1Receptor Activation

    Article • Journal of Neuroscience, December 1997, Society for Neuroscience

    Professor Andrew F Russo

  101. Tissue-specific glucocorticoid regulation of tryptophan hydroxylase mRNA levels

    Article • Molecular Brain Research, September 1997, Elsevier

    Professor Andrew F Russo

  102. Binding of Upstream Stimulatory Factor and a Cell-specific Activator to the Calcitonin/Calcitonin Gene-related Peptide Enhancer

    Article • Journal of Biological Chemistry, July 1997, Elsevier

    Professor Andrew F Russo

  103. Thyroid parafollicular cells

    Article • Molecular Neurobiology, December 1996, Springer Science + Business Media

    Professor Andrew F Russo

  104. Expression and development of a functional plasmalemmal 5-hydroxytryptamine transporter by thyroid follicular cells.

    Article • Endocrinology, October 1996, Endocrine Society

    Professor Andrew F Russo

  105. Induction of a serotonergic and neuronal phenotype in thyroid C-cells

    Article • Journal of Neuroscience, September 1995, Society for Neuroscience

    Professor Andrew F Russo

  106. Serotonergic Neuronal Properties in C-Cell Lines

    Article • Methods, June 1995, Elsevier

    Professor Andrew F Russo

  107. Retinoic acid repression of cell-specific helix-loop-helix-octamer activation of the calcitonin/calcitonin gene-related peptide enhancer.

    Article • Molecular and Cellular Biology, October 1993, ASM Journals

    Professor Andrew F Russo

  108. Retinoic acid is enriched in Hensen's node and is developmentally regulated in the early chicken embryo.

    Article • Proceedings of the National Academy of Sciences, November 1992, Proceedings of the National Academy of Sciences

    Professor Andrew F Russo

  109. A rapid PCR protocol for identification of differentially expressed genes from a cDNA library.

    Article • Genome Research, February 1992, Cold Spring Harbor Laboratory Press

    Professor Andrew F Russo

  110. Neuronal properties of a thyroid C-cell line: partial repression by dexamethasone and retinoic acid.

    Article • Molecular Endocrinology, February 1992, Endocrine Society

    Professor Andrew F Russo

  111. Characterization of the calcitonin/CGRP gene in Williams syndrome

    Article • American Journal of Medical Genetics, April 1991, Wiley

    Professor Andrew F Russo

  112. Isolation of cDNA clones encoding small nuclear ribonucleoparticle-associated proteins with different tissue specificities.

    Article • Proceedings of the National Academy of Sciences, December 1989, Proceedings of the National Academy of Sciences

    Professor Andrew F Russo

  113. Neuronal Expression of chimeric genes in transgenic mice

    Article • Neuron, June 1988, Elsevier

    Professor Andrew F Russo

  114. Molecular cloning of a brain-specific calcium/calmodulin-dependent protein kinase.

    Article • Proceedings of the National Academy of Sciences, August 1987, Proceedings of the National Academy of Sciences

    Professor Andrew F Russo

  115. Neuron-specific alternative RNA processing in transgenic mice expressing a metallothionein-calcitonin fusion gene

    Article • Cell, May 1987, Elsevier

    Professor Andrew F Russo

  116. Neuron-specific alternative RNA processing in neuroendocrine gene expression

    Article • Biochemical Society Transactions, February 1987, Portland Press Ltd.

    Professor Andrew F Russo

  117. Identification of the tip-encoded receptor in bacterial sensing

    Article • Journal of Bacteriology, January 1986, ASM Journals

    Professor Andrew F Russo

  118. Role of Silicon in Diatom Metabolism

    Article • PLANT PHYSIOLOGY, November 1984, Oxford University Press (OUP)

    Professor Andrew F Russo

  119. Separation of Signal Transduction and Adaptation Functions of the Aspartate Receptor in Bacterial Sensing

    Article • Science, June 1983, American Association for the Advancement of Science

    Professor Andrew F Russo

  120. Information Processing in a Sensory System

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1983, Cold Spring Harbor Laboratory Press

    Professor Andrew F Russo