All Stories

  1. Design, simulate, refine: simulation-guided clinical trials for accelerated drug development

    Article • Nature Reviews Cancer, July 2026, Springer Science + Business Media

    Professor Andrew P Grieve

  2. Pre‐Posterior Distributions in Drug Development and Their Properties

    Article • Pharmaceutical Statistics, November 2024, Wiley

    Professor Andrew P Grieve

  3. Performance Evaluation of Interim Analysis in Bioequivalence Studies

    Article • Therapeutic Innovation & Regulatory Science, May 2024, Springer Science + Business Media

    Kazushi Maruo, Professor Andrew P Grieve

  4. Absolute Power Corrupts Absolutely: A Review of the Use of Unconditional Probabilities in the Planning of Clinical Trials

    Article • January 2024, Springer Science + Business Media

    Professor Andrew P Grieve

  5. Probability of success and group sequential designs

    Article • Pharmaceutical Statistics, November 2023, Wiley

    Professor Andrew P Grieve

  6. On implementing J effreys' substitution likelihood for B ayesian inference concerning the medians of unknown distributions

    Article • Pharmaceutical Statistics, December 2022, Wiley

    Professor Andrew P Grieve

  7. Hybrid Frequentist/Bayesian Power and Bayesian Power in Planning Clinical Trials

    Article • April 2022, Taylor & Francis

    Professor Andrew P Grieve

  8. Optimising the trade‐off between type I and II error rates in the Bayesian context

    Article • Pharmaceutical Statistics, February 2021, Wiley

    Professor Andrew P Grieve

  9. How to design a dose-finding study using the continual reassessment method

    Article • BMC Medical Research Methodology, January 2019, Springer Science + Business Media

    Professor Andrew P Grieve

  10. Minimizing Patient Burden Through the Use of Historical Subject-Level Data in Innovative Confirmatory Clinical Trials

    Article • Therapeutic Innovation & Regulatory Science, June 2018, SAGE Publications

    Jessica Lim, Professor Andrew P Grieve

  11. Justify your alpha

    Article • Nature Human Behaviour, February 2018, Springer Science + Business Media

    Dr. Ahmed Khalil, Professor Andrew P Grieve, Dr. Amanda Friesen, Professor Emily S. Cross

  12. Statistical issues in first-in-human studies on BIA 10-2474: Neglected comparison of protocol against practice

    Article • Pharmaceutical Statistics, February 2017, Wiley

    Professor Stephen J Senn, Professor Andrew P Grieve

  13. Response-adaptive clinical trials: case studies in the medical literature

    Article • Pharmaceutical Statistics, October 2016, Wiley

    Professor Andrew P Grieve

  14. Simulation-based sample-sizing and power calculations in logistic regression with partial prior information

    Article • Pharmaceutical Statistics, September 2016, Wiley

    Professor Andrew P Grieve, Dr Shah-Jalal Sarker

  15. The predictive distribution of the residual variability in the linear-fixed effects model for clinical cross-over trials

    Article • Biometrical Journal, March 2016, Wiley

    Professor Andrew P Grieve

  16. Idle thoughts of a ‘well-calibrated’ Bayesian in clinical drug development

    Article • Pharmaceutical Statistics, January 2016, Wiley

    Professor Andrew P Grieve

  17. How to test hypotheses if you must

    Article • Pharmaceutical Statistics, January 2015, Wiley

    Professor Andrew P Grieve

  18. Limitations of within-person study designs

    Article • Journal of Clinical Epidemiology, December 2013, Elsevier

    Professor Andrew P Grieve

  19. Medical Statistics

    Article • April 2013, Wiley

    Professor Andrew P Grieve

  20. Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: Cohort study using the General Practice Research Database

    Article • Seizure, January 2013, Elsevier

    Professor Andrew P Grieve

  21. Advancing clinical trial design in pulmonary hypertension

    Article • Pulmonary Circulation, January 2013, University of Chicago Press

    Professor Andrew P Grieve

  22. A dual-centre, cohort comparison of open, laparoscopic and robotic-assisted radical cystectomy

    Article • International Journal of Clinical Practice, April 2012, Wiley

    Professor Andrew P Grieve, Professor Prokar Dasgupta

  23. Within-person study designs had lower precision and greater susceptibility to bias because of trends in exposure than cohort and nested case–control designs

    Article • Journal of Clinical Epidemiology, April 2012, Elsevier

    Professor Andrew P Grieve

  24. Source Data Verification by Statistical Sampling: Issues in Implementation

    Article • Drug Information Journal, March 2012, SAGE Publications

    Professor Andrew P Grieve

  25. Cutaneous lymphocyte antigen and α4β7 T-lymphocyte responses are associated with peanut allergy and tolerance in children

    Article • Allergy, January 2012, Wiley

    Professor Andrew P Grieve

  26. Discussions

    Article • Biometrics, June 2011, Wiley

    Professor Andrew P Grieve

  27. Estimates of Outcomes Up to Ten Years after Stroke: Analysis from the Prospective South London Stroke Register

    Article • PLoS Medicine, May 2011, PLOS

    Professor Andrew P Grieve

  28. Short Term Response To Sildenafil Therapy For Pulmonary Arterial Hypertension Is Associated With Long Term Outcome

    Article • May 2011, American Thoracic Society

    Professor Andrew P Grieve

  29. Parental assessment of adolescent quality of life: can it replace self-assessment?

    Article • Quality of Life Research, April 2011, Springer Science + Business Media

    Professor Andrew P Grieve

  30. Risk and Cumulative Risk of Stroke Recurrence: A Systematic Review and Meta-Analysis

    Article • Stroke, March 2011, Wolters Kluwer Health

    Professor Andrew P Grieve

  31. Cluster randomised trial in the General Practice Research Database: 1. Electronic decision support to reduce antibiotic prescribing in primary care (eCRT study)

    Article • Trials, January 2011, Springer Science + Business Media

    Professor Andrew P Grieve

  32. Potential application of item-response theory to interpretation of medical codes in electronic patient records

    Article • BMC Medical Research Methodology, January 2011, Springer Science + Business Media

    Professor Andrew P Grieve

  33. Cluster Randomized Controlled Trial of a Patient and General Practitioner Intervention to Improve the Management of Multiple Risk Factors After Stroke: Stop Stroke

    Article • Stroke, September 2010, Wolters Kluwer Health

    Professor Andrew P Grieve

  34. Entwicklung der deutschen Version der Patientenzufriedenheits-Skala (SASC) für den Einsatz bei Patienten nach Schlaganfall

    Article • Fortschritte der Neurologie · Psychiatrie, April 2010, Thieme Publishing Group

    Professor Andrew P Grieve

  35. Frequency and predictors for the risk of stroke recurrence up to 10 years after stroke: the South London Stroke Register

    Article • Journal of Neurology Neurosurgery & Psychiatry, May 2009, BMJ

    Professor Andrew P Grieve

  36. Nurse delivered endoscopy

    Article • BMJ, February 2009, BMJ

    Professor Andrew P Grieve

  37. Black and minority ethnic men who have sex with men: a London genitourinary medicine clinic experience

    Article • International Journal of STD & AIDS, September 2008, SAGE Publications

    Professor Andrew P Grieve

  38. Ethnic Group Disparities in 10-Year Trends in Stroke Incidence and Vascular Risk Factors: The South London Stroke Register (SLSR)

    Article • Stroke, June 2008, Wolters Kluwer Health

    Professor Andrew P Grieve

  39. European regulatory agencies should employ full time statisticians

    Article • BMJ, January 2008, BMJ

    Professor Andrew P Grieve

  40. Flexible Design and Efficient Implementation of Adaptive Dose-Finding Studies

    Article • Journal of Biopharmaceutical Statistics, November 2007, Taylor & Francis

    Professor Andrew P Grieve

  41. Discussion of the “White Paper of the PhRMA Working Group on Adaptive Dose-Ranging Designs”

    Article • Journal of Biopharmaceutical Statistics, November 2007, Taylor & Francis

    Professor Andrew P Grieve

  42. Adaptive Designs in Clinical Drug Development: Opportunities, Challenges, and Scope Reflections Following PhRMA's November 2006 Workshop

    Article • Journal of Biopharmaceutical Statistics, November 2007, Taylor & Francis

    Professor Andrew P Grieve

  43. Simulation-based sequential Bayesian design

    Article • Journal of Statistical Planning and Inference, October 2007, Elsevier

    Professor Andrew P Grieve

  44. Statistical issues in first-in-man studies

    Article • Journal of the Royal Statistical Society Series A (Statistics in Society), July 2007, Wiley

    Professor Andrew P Grieve

  45. 25 years of Bayesian methods in the pharmaceutical industry: a personal, statistical bummel

    Article • Pharmaceutical Statistics, January 2007, Wiley

    Professor Andrew P Grieve

  46. The association of post-stroke neurological improvement with risk of subsequent deterioration due to stroke events

    Article • European Journal of Neurology, January 2007, Wiley

    Professor Andrew P Grieve

  47. A Bayesian Decision-Theoretic Dose-Finding Trial

    Article • Decision Analysis, December 2006, INFORMS

    Professor Andrew P Grieve

  48. Guest Editors' Note for the Special Issue on “Design and Analysis of Dose-Response Clinical Trials”

    Article • Journal of Biopharmaceutical Statistics, October 2006, Taylor & Francis

    Professor Andrew P Grieve

  49. Implementation of a Bayesian adaptive design in a proof of concept study

    Article • Pharmaceutical Statistics, January 2006, Wiley

    Professor Andrew P Grieve

  50. The professionalization of the 'shoe clerk'

    Article • Journal of the Royal Statistical Society Series A (Statistics in Society), November 2005, Wiley

    Professor Andrew P Grieve

  51. ASTIN: a Bayesian adaptive dose–response trial in acute stroke

    Article • Clinical Trials, August 2005, SAGE Publications

    Professor Andrew P Grieve

  52. Career story: Pharmaceutical Statistician

    Article • Significance, March 2004, Wiley

    Professor Andrew P Grieve

  53. Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): An Adaptive Dose-Response Study of UK-279,276 in Acute Ischemic Stroke

    Article • Stroke, October 2003, Wolters Kluwer Health

    Professor Andrew P Grieve

  54. The number needed to treat: a useful clinical measure or a case of the Emperor's new clothes?

    Article • Pharmaceutical Statistics, January 2003, Wiley

    Professor Andrew P Grieve

  55. Do statisticians count? A personal view

    Article • Pharmaceutical Statistics, January 2002, Wiley

    Professor Andrew P Grieve

  56. Adaptive Bayesian Designs for Dose-Ranging Drug Trials

    Article • January 2002, Springer Science + Business Media

    Professor Andrew P Grieve

  57. A Comment on Optimal Allocations for Bioequivalence Studies

    Article • Biometrics, December 1999, Oxford University Press (OUP)

    Professor Stephen J Senn, Professor Andrew P Grieve

  58. Issues for statisticians in pharmaco-economic evaluations

    Article • Statistics in Medicine, August 1998, Wiley

    Professor Andrew P Grieve

  59. Issues for statisticians in pharmaco‐economic evaluations

    Article • Statistics in Medicine, August 1998, Wiley

    Professor Andrew P Grieve

  60. Bayesian and frequentist approaches to the cross-over trial

    Article • Journal of Biopharmaceutical Statistics, January 1998, Taylor & Francis

    Professor Stephen J Senn, Professor Andrew P Grieve

  61. Joint equivalence of means and variances of two populations

    Article • Journal of Biopharmaceutical Statistics, January 1998, Taylor & Francis

    Professor Andrew P Grieve

  62. A Comment on Interim Analyses in Crossover Trials

    Article • Biometrics, December 1996, JSTOR

    Professor Stephen J Senn, Professor Andrew P Grieve

  63. Extending a Bayesian Analysis of the Two-Period Crossover to Accommodate Missing Data

    Article • Biometrika, June 1995, JSTOR

    Professor Andrew P Grieve

  64. Extending a Bayesian analysis of the two-period crossover to accommodate missing data

    Article • Biometrika, January 1995, Oxford University Press (OUP)

    Professor Andrew P Grieve

  65. A Further Note on Sampling to Locate Rare Defectives with Strong Prior Evidence

    Article • Biometrika, December 1994, JSTOR

    Professor Andrew P Grieve

  66. Bayesian analyses of two-treatment crossover studies

    Article • Statistical Methods in Medical Research, December 1994, SAGE Publications

    Professor Andrew P Grieve

  67. Crossover studies

    Article • Clinical Pharmacology & Therapeutics, July 1994, Nature

    Professor Andrew P Grieve

  68. Extending a Bayesian analysis of the two-period crossover to allow for baseline measurements

    Article • Statistics in Medicine, May 1994, Wiley

    Professor Andrew P Grieve

  69. Statistical Methods in Analytical Chemistry.

    Article • Journal of the Royal Statistical Society Series A (Statistics in Society), January 1994, JSTOR

    Professor Andrew P Grieve

  70. A further note on sampling to locate rare defectives with strong prior evidence

    Article • Biometrika, January 1994, Oxford University Press (OUP)

    Professor Andrew P Grieve

  71. Cross-Over Trials in Clinical Research.

    Article • DELETED, January 1994, JSTOR

    Professor Andrew P Grieve

  72. Measuring Your Posterior Beliefs That you can Count Properly

    Article • DELETED, January 1994, JSTOR

    Professor Andrew P Grieve

  73. Design and analysis of bioavailability and bioequivalence studies. Shein-Chung Chow and Jen-Pei Liu, Marcel Dekker, New York, 1992. No. of pages: x + 416. Price: $125. ISBN 0-8247-8682-3

    Article • Statistics in Medicine, November 1993, Wiley

    Professor Andrew P Grieve

  74. Confidence Intervals on Variance Components.

    Article • Journal of the Royal Statistical Society Series A (Statistics in Society), January 1993, JSTOR

    Professor Andrew P Grieve

  75. `Student'-A Statistical Biography of William Sealy Gosset: Based on the Writings of E. S. Pearson.

    Article • DELETED, January 1993, JSTOR

    Professor Andrew P Grieve

  76. Confidence Intervals and Sample Sizes

    Article • Biometrics, December 1991, JSTOR

    Professor Andrew P Grieve

  77. On the construction of shortest confidence intervals and Bayesian highest posterior density intervals

    Article • Journal of Veterinary Pharmacology and Therapeutics, December 1991, Wiley

    Professor Andrew P Grieve

  78. Predictive Probability in Clinical Trials

    Article • Biometrics, March 1991, JSTOR

    Professor Andrew P Grieve

  79. A further note on some wishart expectations

    Article • Metrika, December 1988, Springer Science + Business Media

    Professor Andrew P Grieve

  80. A Quasirandom Approach to Integration in Bayesian Statistics

    Article • The Annals of Statistics, June 1988, Institute of Mathematical Statistics

    Professor Andrew P Grieve

  81. A Two-Stage Procedure for Bioequivalence Studies

    Article • Biometrics, December 1987, JSTOR

    Professor Andrew P Grieve

  82. Discussion of Piegorsch and Gladen (1986)

    Article • Technometrics, November 1987, Taylor & Francis

    Professor Andrew P Grieve

  83. A Note on the Analysis of the Two-Period Crossover Design When the Period-Treatment Interaction is Significant

    Article • Biometrical Journal, January 1987, Wiley

    Professor Andrew P Grieve

  84. Applications of Bayesian Software: Two Examples

    Article • DELETED, January 1987, JSTOR

    Professor Andrew P Grieve

  85. Bayesian Methods in Practice: Experiences in the Pharmaceutical Industry

    Article • Journal of the Royal Statistical Society Series C (Applied Statistics), January 1986, JSTOR

    Professor Andrew P Grieve

  86. The role of Schmidt-Lanterman incisures in Wallerian degeneration

    Article • Acta Neuropathologica, January 1986, Springer Science + Business Media

    Professor Andrew P Grieve

  87. A Bayesian Analysis of the Two-Period Crossover Design for Clinical Trials

    Article • Biometrics, December 1985, JSTOR

    Professor Andrew P Grieve

  88. A non-parametric confidence interval method

    Article • European Journal of Clinical Pharmacology, January 1985, Springer Science + Business Media

    Professor Andrew P Grieve

  89. Seasonal variation of temperatures in rabbits

    Article • Laboratory Animals, July 1984, SAGE Publications

    Professor Andrew P Grieve

  90. Tests of sphericity of normal distributions and the analysis of repeated measures designs

    Article • Psychometrika, June 1984, Springer Science + Business Media

    Professor Andrew P Grieve

  91. Fully automated and fast image analysis of autoradiographs with a TAS-Leitz. Determination of size, Feulgen fluorescence and grain counts of individual nuclei and their evaluation by a simplified cluster analysis

    Article • Histochemistry and Cell Biology, January 1984, Springer Science + Business Media

    Professor Andrew P Grieve

  92. Bayesian Approach to Bioequivalence Assessment: An Example

    Article • Journal of Pharmaceutical Sciences, October 1983, Elsevier

    Professor Andrew P Grieve

  93. Pharmacokinetic and pharmacodynamic studies of single oral doses of metoprolol in normal volunteers

    Article • European Journal of Drug Metabolism and Pharmacokinetics, April 1977, Springer Science + Business Media

    Professor Andrew P Grieve

  94. Medical Statistics

    Article • Wiley

    Professor Andrew P Grieve

  95. Medical Statistics

    Article • Wiley

    Professor Andrew P Grieve