All Stories

  1. stackPredAMR – A stacked random forest approach improves AMR phenotype prediction for multiple species and antimicrobial agents

    Article • Bioinformatics Advances, June 2026, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  2. Factors Governing the Cross-Species Virulence of Shiga Toxin-Producing Escherichia coli

    Article • Pathogens, March 2026, MDPI AG

    Prof. Dr. Alexander Mellmann

  3. The dark matter of bacterial genomic surveillance—antimicrobial resistance plasmid transmissions in the hospital setting

    Article • Journal of Clinical Microbiology, June 2025, ASM Journals

    Prof. Dr. Alexander Mellmann

  4. Carbon source utilization in hybrid Shiga toxin-producing and uropathogenic Escherichia coli indicates uropathogenic origin

    Article • International Journal of Medical Microbiology, June 2025, Elsevier

    Prof. Dr. Alexander Mellmann

  5. Experimental evolution of a pathogen confronted with innate immune memory increases variation in virulence

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Prof. Dr. Alexander Mellmann

  6. Evaluation of a microfluidic-based point-of-care prototype with customized chip for detection of bacterial clusters

    Article • Microbiology Spectrum, December 2024, ASM Journals

    Prof. Dr. Alexander Mellmann

  7. Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract

    Article • Emerging Microbes & Infections, September 2024, Taylor & Francis

    Prof. Dr. Alexander Mellmann

  8. Plasma-Activated Tap Water with Oxidative Potential Has an Inactivating Effect on Microbiological Contaminants in Aqueous Suspensions

    Article • Pathogens, June 2024, MDPI AG

    Prof. Dr. Alexander Mellmann

  9. The host-targeted antiviral drug Zapnometinib exhibits a high barrier to the development of SARS-CoV-2 resistance

    Article • Antiviral Research, May 2024, Elsevier

    Prof. Dr. Alexander Mellmann

  10. Various mutations in icaR, the repressor of the icaADBC locus, occur in mucoid Staphylococcus aureus isolates recovered from the airways of people with cystic fibrosis

    Article • Microbes and Infection, May 2024, Elsevier

    Prof. Dr. Alexander Mellmann

  11. Generation of Plasma-Activated Fluids for Successful Disinfection of Pseudomonas aeruginosa in Liquid Environments and Determination of Microbial Damage

    Article • Plasma, November 2023, MDPI AG

    Prof. Dr. Alexander Mellmann

  12. Clostridioides difficile from Fecally Contaminated Environmental Sources: Resistance and Genetic Relatedness from a Molecular Epidemiological Perspective

    Article • Microorganisms, October 2023, MDPI AG

    Prof. Dr. Alexander Mellmann

  13. Occurrence and prevalence of Legionella species in dental chair units in Germany with a focus on risk factors

    Article • European Journal of Clinical Microbiology & Infectious Diseases, September 2023, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  14. Molecular Characterization of Clinical Linezolid-Resistant Staphylococcus epidermidis in a Tertiary Care Hospital

    Article • Microorganisms, July 2023, MDPI AG

    Prof. Dr. Alexander Mellmann

  15. Cell-intrinsic genomic reassortment of pandemic H1N1 2009 and Eurasian avian-like swine influenza viruses results in potentially zoonotic variants

    Article • Emerging Microbes & Infections, May 2023, Taylor & Francis

    Prof. Dr. Alexander Mellmann

  16. Impact of Chlorine Dioxide on Pathogenic Waterborne Microorganisms Occurring in Dental Chair Units

    Article • Microorganisms, April 2023, MDPI AG

    Prof. Dr. Alexander Mellmann

  17. Clinical Evidence for the Use of Octenidine Dihydrochloride to Prevent Healthcare-Associated Infections and Decrease Staphylococcus aureus Carriage or Transmission—A Review

    Article • Pathogens, April 2023, MDPI AG

    Prof. Dr. Alexander Mellmann

  18. Application of Digital Holographic Microscopy to Analyze Changes in T-Cell Morphology in Response to Bacterial Challenge

    Article • Cells, February 2023, MDPI AG

    Prof. Dr. Alexander Mellmann

  19. The ubiquitination landscape of the influenza A virus polymerase

    Article • Nature Communications, February 2023, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  20. Molecular Epidemiology, Clinical Course, and Implementation of Specific Hygiene Measures in Hospitalised Patients with Clostridioides difficile Infection in Brandenburg, Germany

    Article • Microorganisms, December 2022, MDPI AG

    Prof. Dr. Alexander Mellmann

  21. Single Nucleotide Polymorphism-Based Real-Time PCR Screening Assay for Rapid Tracking of Bacterial Infection Clusters To Complement Whole-Genome Sequencing Efforts during Outbreak Investigations

    Article • Microbiology Spectrum, December 2022, ASM Journals

    Prof. Dr. Alexander Mellmann

  22. Development and Evaluation of a Core Genome Multilocus Sequencing Typing (cgMLST) Scheme for Serratia marcescens Molecular Surveillance and Outbreak Investigations

    Article • Journal of Clinical Microbiology, November 2022, ASM Journals

    Prof. Dr. Alexander Mellmann

  23. A Robust One-Step Recombineering System for Enterohemorrhagic Escherichia coli

    Article • Microorganisms, August 2022, MDPI AG

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  24. Outbreak of MRSA in a Gynecology/Obstetrics Department during the COVID-19 Pandemic: A Cautionary Tale

    Article • Microorganisms, March 2022, MDPI AG

    Prof. Dr. Alexander Mellmann

  25. The Use of Long-Read Sequencing Technologies in Infection Control: Horizontal Transfer of a blaCTX-M-27 Containing lncFII Plasmid in a Patient Screening Sample

    Article • Microorganisms, February 2022, MDPI AG

    Prof. Dr. Alexander Mellmann

  26. Investigating Morphological Changes of T-lymphocytes after Exposure with Bacterial Determinants for Early Detection of Septic Conditions

    Article • Microorganisms, February 2022, MDPI AG

    Prof. Dr. Alexander Mellmann

  27. The ubiquitination landscape of the Influenza A Virus polymerase

    Article • February 2022, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  28. Molecular Epidemiology of Vancomycin-Resistant Enterococci Bloodstream Infections in Germany: A Population-Based Prospective Longitudinal Study

    Article • Microorganisms, January 2022, MDPI AG

    Prof. Dr. Alexander Mellmann

  29. Phenotypic Variants of Bacterial Colonies in Microbiological Diagnostics: How Often Are They Indicative of Differing Antimicrobial Susceptibility Patterns?

    Article • Microbiology Spectrum, October 2021, ASM Journals

    Prof. Dr. Alexander Mellmann

  30. In Vivo Secretion of β-Lactamase-Carrying Outer Membrane Vesicles as a Mechanism of β-Lactam Therapy Failure

    Article • Membranes, October 2021, MDPI AG

    Prof. Dr. Alexander Mellmann

  31. Comparative phenotypic characterization of hybrid Shiga toxin-producing / uropathogenic Escherichia coli, canonical uropathogenic and Shiga toxin-producing Escherichia coli

    Article • International Journal of Medical Microbiology, October 2021, Elsevier

    Prof. Dr. Alexander Mellmann

  32. Primary Human Colon Epithelial Cells (pHCoEpiCs) Do Express the Shiga Toxin (Stx) Receptor Glycosphingolipids Gb3Cer and Gb4Cer and Are Largely Refractory but Not Resistant towards Stx

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Prof. Dr. Alexander Mellmann

  33. Primary Human Renal Proximal Tubular Epithelial Cells (pHRPTEpiCs): Shiga Toxin (Stx) Glycosphingolipid Receptors, Stx Susceptibility, and Interaction with Membrane Microdomains

    Article • Toxins, July 2021, MDPI AG

    Prof. Dr. Alexander Mellmann

  34. Pilot Study on Alteration of LA-MRSA Status of Pigs during Fattening Period on Straw Bedding by Two Types of Cleaning

    Article • Antibiotics, May 2021, MDPI AG

    Prof. Dr. Alexander Mellmann

  35. Molecular epidemiology and antimicrobial resistance of Clostridioides difficile in Germany, 2014–2019

    Article • International Journal of Medical Microbiology, May 2021, Elsevier

    Prof. Dr. Alexander Mellmann

  36. Establishment and Evaluation of a Core Genome Multilocus Sequence Typing Scheme for Whole-Genome Sequence-Based Typing of Pseudomonas aeruginosa

    Article • Journal of Clinical Microbiology, February 2021, ASM Journals

    Prof. Dr. Alexander Mellmann

  37. Shiga Toxin (Stx)-Binding Glycosphingolipids of Primary Human Renal Cortical Epithelial Cells (pHRCEpiCs) and Stx-Mediated Cytotoxicity

    Article • Toxins, February 2021, MDPI AG

    Prof. Dr. Alexander Mellmann

  38. Integrating evolutionary aspects into dual-use discussion: the cases of influenza virus and enterohemorrhagic Escherichia coli

    Article • Evolution Medicine and Public Health, January 2021, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  39. A child with soft-tissue infection and lymphadenitis

    Article • New Microbes and New Infections, November 2020, Elsevier

    Prof. Dr. Alexander Mellmann

  40. Molecular characterization of Staphylococcus aureus complex from fomites in Nigeria

    Article • Infection Genetics and Evolution, November 2020, Elsevier

    Prof. Dr. Alexander Mellmann

  41. Prevalence and Epidemiology of Multidrug-Resistant Pathogens in the Food Chain and the Urban Environment in Northwestern Germany

    Article • Antibiotics, October 2020, MDPI AG

    Prof. Dr. Alexander Mellmann

  42. Healthcare-Associated SARS-CoV-2 Transmission—Experiences from a German University Hospital

    Article • Microorganisms, September 2020, MDPI AG

    Prof. Dr. Alexander Mellmann

  43. Modeling Native EHEC Outer Membrane Vesicles by Creating Synthetic Surrogates

    Article • Microorganisms, May 2020, MDPI AG

    Prof. Dr. Alexander Mellmann

  44. Single Blinded Study on the Feasibility of Decontaminating LA-MRSA in Pig Compartments under Routine Conditions

    Article • Antibiotics, March 2020, MDPI AG

    Prof. Dr. Alexander Mellmann

  45. RAB5A and TRAPPC6B are novel targets for Shiga toxin 2a inactivation in kidney epithelial cells

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  46. Transmission of Vancomycin-Resistant Enterococci in the Hospital Setting: Uncovering the Patient–Environment Interplay

    Article • Microorganisms, January 2020, MDPI AG

    Prof. Dr. Alexander Mellmann

  47. Structural Insights into Escherichia coli Shiga Toxin (Stx) Glycosphingolipid Receptors of Porcine Renal Epithelial Cells and Inhibition of Stx-Mediated Cellular Injury Using Neoglycolipid-Spiked Glycovesicles

    Article • Microorganisms, November 2019, MDPI AG

    Prof. Dr. Alexander Mellmann

  48. Genotypic Characterization of Livestock-Associated Methicillin-Resistant Staphylococcus aureus Isolates of Clonal Complex 398 in Pigsty Visitors: Transient Carriage or Persistence?

    Article • Journal of Clinical Microbiology, October 2019, ASM Journals

    Prof. Dr. Alexander Mellmann

  49. Origin and Evolution of Hybrid Shiga Toxin-Producing and Uropathogenic Escherichia coli Strains of Sequence Type 141

    Article • Journal of Clinical Microbiology, October 2019, ASM Journals

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  50. Risk Factors for Long-Term Vancomycin-Resistant Enterococci Persistence—A Prospective Longitudinal Study

    Article • Microorganisms, September 2019, MDPI AG

    Prof. Dr. Alexander Mellmann

  51. L-selectin shedding affects bacterial clearance in the lung - a new regulatory pathway for integrin-outside-in signaling

    Article • Blood, July 2019, American Society of Hematology

    Prof. Dr. Alexander Mellmann

  52. Microevolution of epidemiological highly relevant non-O157 enterohemorrhagic Escherichia coli of serogroups O26 and O111

    Article • International Journal of Medical Microbiology, December 2018, Elsevier

    Prof. Dr. Alexander Mellmann

  53. In vivo competition and horizontal gene transfer among distinct Staphylococcus aureus lineages as major drivers for adaptational changes during long-term persistence in humans

    Article • BMC Microbiology, October 2018, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann, Dr Francesco Catania

  54. Comparative virulence characterization of the Shiga toxin phage-cured Escherichia coli O104:H4 and enteroaggregative Escherichia coli

    Article • International Journal of Medical Microbiology, October 2018, Elsevier

    Prof. Dr. Alexander Mellmann

  55. Enterohemorrhagic Escherichia coli O157 outer membrane vesicles induce interleukin 8 production in human intestinal epithelial cells by signaling via Toll-like receptors TLR4 and TLR5 and activation of the nuclear factor NF-κB

    Article • International Journal of Medical Microbiology, October 2018, Elsevier

    Prof. Dr. Alexander Mellmann

  56. Comparative Secretome Analyses of Human and Zoonotic Staphylococcus aureus Isolates CC8, CC22, and CC398

    Article • Molecular & Cellular Proteomics, September 2018, American Society for Biochemistry & Molecular Biology (ASBMB)

    Prof. Dr. Alexander Mellmann

  57. Core elements of the vegetative replication control of the Inc1 plasmid pO104_90 of Escherichia coli O104:H4 also regulate its transfer frequency

    Article • International Journal of Medical Microbiology, July 2018, Elsevier

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  58. Management of superficial and deep-seated Staphylococcus aureus skin and soft tissue infections in sub-Saharan Africa: a post hoc analysis of the StaphNet cohort

    Article • Infection, April 2018, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  59. Defining and Evaluating a Core Genome Multilocus Sequence Typing Scheme for Genome-Wide Typing of Clostridium difficile

    Article • Journal of Clinical Microbiology, April 2018, ASM Journals

    Prof. Dr. Alexander Mellmann

  60. Transmission Risk on a Neonatal Intensive Care Unit: Escherichia coli versus Klebsiella pneumoniae

    Article • Canadian Journal of Infectious Diseases and Medical Microbiology, January 2018, Hindawi Publishing Corporation

    Prof. Dr. Alexander Mellmann

  61. Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:H− Isolates from Czech Patients with Novel Plasmid Composition Not Previously Seen in German Isolates

    Article • Applied and Environmental Microbiology, September 2017, ASM Journals

    Martina Bielaszewska, Prof. Dr. Alexander Mellmann

  62. Genome Sequences of the First WHO Repository of Platelet Transfusion-Relevant Bacterial Reference Strains

    Article • Genome Announcements, July 2017, ASM Journals

    Prof. Dr. Alexander Mellmann

  63. Antibiotic-Mediated Modulations of Outer Membrane Vesicles in Enterohemorrhagic Escherichia coli O104:H4 and O157:H7

    Article • Antimicrobial Agents and Chemotherapy, June 2017, ASM Journals

    Martina Bielaszewska, Prof. Dr. Alexander Mellmann

  64. In the centre of an epidemic: Fifteen years of LA-MRSA CC398 at the University Hospital Münster

    Article • Veterinary Microbiology, February 2017, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  65. High Interlaboratory Reproducibility and Accuracy of Next-Generation-Sequencing-Based Bacterial Genotyping in a Ring Trial

    Article • Journal of Clinical Microbiology, January 2017, ASM Journals

    Prof. Dr. Alexander Mellmann, Prof dr. John W Rossen

  66. Dynamic in vivo mutations within the ica operon during persistence of Staphylococcus aureus in the airways of cystic fibrosis patients

    Article • PLoS Pathogens, November 2016, PLOS

    Prof. Dr. Alexander Mellmann

  67. A geospatial analysis of flies and the spread of antimicrobial resistant bacteria

    Article • International Journal of Medical Microbiology, November 2016, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  68. Real-Time Genome Sequencing of Resistant Bacteria Provides Precision Infection Control in an Institutional Setting

    Article • Journal of Clinical Microbiology, August 2016, ASM Journals

    Prof. Dr. Alexander Mellmann, Prof. Dr. med. Karsten Becker

  69. Whole-Genome Sequencing Elucidates Epidemiology of Nosocomial Clusters of Acinetobacter baumannii

    Article • Journal of Clinical Microbiology, June 2016, ASM Journals

    Prof. Dr. Alexander Mellmann

  70. Molecular Characterization of Human Atypical Sorbitol-Fermenting Enteropathogenic Escherichia coli O157 Reveals High Diversity

    Article • Journal of Clinical Microbiology, March 2016, ASM Journals

    Prof. Dr. Alexander Mellmann

  71. Detecting Staphylococcus aureus Virulence and Resistance Genes: a Comparison of Whole-Genome Sequencing and DNA Microarray Technology

    Article • Journal of Clinical Microbiology, January 2016, ASM Journals

    Prof. Dr. Alexander Mellmann

  72. Phosphorylation of influenza A virus NS1 protein at threonine 49 suppresses its interferon antagonistic activity

    Article • Cellular Microbiology, January 2016, Wiley

    Prof. Dr. Alexander Mellmann

  73. The association of ESBL-producing Enterobacteriaceae (ESBL-E) carriage in humans with pigs – a reply

    Article • Epidemiology and Infection, November 2015, Cambridge University Press

    Prof. Dr. Alexander Mellmann

  74. Detection ofmecA- andmecC-Positive Methicillin-Resistant Staphylococcus aureus (MRSA) Isolates by the New Xpert MRSA Gen 3 PCR Assay: TABLE 1

    Article • Journal of Clinical Microbiology, October 2015, ASM Journals

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  75. Molecular epidemiology of Enterococcus faecium

    Article • Journal of Clinical Microbiology, September 2015, ASM Journals

    Dr Rob JL Willems, Prof. Dr. Alexander Mellmann, Dr Janetta Top

  76. Is Shiga Toxin-Negative Escherichia coli O157:H7 Enteropathogenic or Enterohemorrhagic Escherichia coli? Comprehensive Molecular Analysis Using Whole-Genome Sequencing

    Article • Journal of Clinical Microbiology, August 2015, ASM Journals

    Prof dr. John W Rossen, Prof. Dr. Alexander Mellmann

  77. Virulence from vesicles: Novel mechanisms of host cell injury by Escherichia coli O104:H4 outbreak strain

    Article • Scientific Reports, August 2015, Nature

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  78. State-wide surveillance of antibiotic resistance patterns and spa types of methicillin-resistant Staphylococcus aureus from blood cultures in North Rhine-Westphalia, 2011–2013

    Article • Clinical Microbiology and Infection, August 2015, Elsevier

    Prof. Dr. Alexander Mellmann

  79. Highly Virulent Non-O157 Enterohemorrhagic Escherichia coli (EHEC) Serotypes Reflect Similar Phylogenetic Lineages, Providing New Insights into the Evolution of EHEC

    Article • Applied and Environmental Microbiology, July 2015, ASM Journals

    Prof. Dr. Alexander Mellmann

  80. Molecular Typing of Enterobacteriaceae from Pig Holdings in North-Western Germany Reveals Extended- Spectrum and AmpC β-Lactamases Producing but no Carbapenem Resistant Ones

    Article • PLOS One, July 2015, PLOS

    Prof. Dr. Alexander Mellmann, Prof dr. John W Rossen

  81. Low-level antimicrobial resistance of Enterobacteriaceae isolated from the nares of pig-exposed persons

    Article • Epidemiology and Infection, July 2015, Cambridge University Press

    Prof. Dr. Alexander Mellmann

  82. Defining and Evaluating a Core Genome Multilocus Sequence Typing Scheme for Whole-Genome Sequence-Based Typing of Listeria monocytogenes

    Article • Journal of Clinical Microbiology, July 2015, ASM Journals

    Prof. Dr. Alexander Mellmann

  83. Is Africa the origin of major Haitian Staphylococcus aureus lineages?

    Article • International Journal of Infectious Diseases, May 2015, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  84. Rapid High Resolution Genotyping of Francisella tularensis by Whole Genome Sequence Comparison of Annotated Genes (“MLST+”)

    Article • PLOS One, April 2015, PLOS

    Prof. Dr. Alexander Mellmann

  85. Staphylococcus aureus complex from animals and humans in three remote African regions

    Article • Clinical Microbiology and Infection, April 2015, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  86. Ensuring backwards compatibility: traditional genotyping efforts in the era of whole genome sequencing

    Article • Clinical Microbiology and Infection, April 2015, Elsevier

    Prof. Dr. Alexander Mellmann

  87. Agitation Down-Regulates Immunoglobulin Binding Protein EibG Expression in Shiga Toxin-Producing Escherichia coli (STEC)

    Article • PLOS One, March 2015, PLOS

    Prof. Dr. Alexander Mellmann

  88. Co-detection of Panton-Valentine leukocidin encoding genes and cotrimoxazole resistance in Staphylococcus aureus in Gabon: implications for HIV-patients’ care

    Article • Frontiers in Microbiology, February 2015, Frontiers

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  89. Staphylococcus aureus spa type t437: identification of the most dominant community-associated clone from Asia across Europe

    Article • Clinical Microbiology and Infection, February 2015, Elsevier

    Prof. Dr. Alexander Mellmann

  90. Label-Free Imaging and Spectroscopic Analysis of Intracellular Bacterial Infections

    Article • Analytical Chemistry, January 2015, American Chemical Society (ACS)

    Prof. Dr. Alexander Mellmann

  91. Are cases of Methicillin-resistant Staphylococcus aureus clonal complex (CC) 398 among humans still livestock-associated?

    Article • International Journal of Medical Microbiology, January 2015, Elsevier

    Prof. Dr. Alexander Mellmann

  92. Transcriptional adaptations during long-term persistence of Staphylococcus aureus in the airways of a cystic fibrosis patient

    Article • International Journal of Medical Microbiology, January 2015, Elsevier

    Prof. Dr. Alexander Mellmann

  93. Enterohemorrhagic E. coli (EHEC): Environmental-Vehicle-Human Interface

    Article • December 2014, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  94. Molecular characterization of Shigella spp. from patients in Gabon 2011-2013

    Article • Transactions of the Royal Society of Tropical Medicine and Hygiene, November 2014, Oxford University Press (OUP)

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  95. Development and evaluation of a novel universal  -lactamase gene subtyping assay for blaSHV, blaTEM and blaCTX-M using clinical and livestock-associated Escherichia coli

    Article • Journal of Antimicrobial Chemotherapy, November 2014, Oxford University Press (OUP)

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  96. The risk to import ESBL-producing Enterobacteriaceae and Staphylococcus aureus through chicken meat trade in Gabon

    Article • BMC Microbiology, November 2014, Springer Science + Business Media

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  97. Trends in antimicrobial non-susceptibility in methicillin-resistant Staphylococcus aureus from Germany (2004–2011)

    Article • Clinical Microbiology and Infection, September 2014, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  98. Inactivation of thyA in Staphylococcus aureus Attenuates Virulence and Has a Strong Impact on Metabolism and Virulence Gene Expression

    Article • mBio, July 2014, ASM Journals

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  99. Whole genome sequencing as a tool to investigate a cluster of seven cases of listeriosis in Austria and Germany, 2011–2013

    Article • Clinical Microbiology and Infection, May 2014, Elsevier

    Professor Franz Allerberger, Prof. Dr. Alexander Mellmann

  100. Bacterial Whole-Genome Sequencing Revisited: Portable, Scalable, and Standardized Analysis for Typing and Detection of Virulence and Antibiotic Resistance Genes

    Article • Journal of Clinical Microbiology, April 2014, ASM Journals

    Prof. Dr. Alexander Mellmann

  101. Hemolytic Uremic Syndrome in a 65-Year-Old Male Linked to a Very Unusual Type of stx2e- and eae-Harboring O51:H49 Shiga Toxin-Producing Escherichia coli

    Article • Journal of Clinical Microbiology, February 2014, ASM Journals

    Professor Roger Stephan, Prof. Dr. Alexander Mellmann

  102. Heteropathogenic virulence and phylogeny reveal phased pathogenic metamorphosis inEscherichia coliO2:H6

    Article • EMBO Molecular Medicine, January 2014, EMBO

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  103. Enterohemorrhagic Escherichia coli Hemolysin Employs Outer Membrane Vesicles to Target Mitochondria and Cause Endothelial and Epithelial Apoptosis

    Article • PLoS Pathogens, December 2013, PLOS

    Prof. Dr. Alexander Mellmann

  104. Corrigendum: Updating benchtop sequencing performance comparison

    Article • Nature Biotechnology, December 2013, Nature

    Fritz Sedlazeck, Prof. Dr. Alexander Mellmann

  105. Characterization of Escherichia coli Isolates from Hospital Inpatients or Outpatients with Urinary Tract Infection

    Article • Journal of Clinical Microbiology, November 2013, ASM Journals

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  106. Evolution of Enterohemorrhagic Escherichia coli O26 Based on Single-Nucleotide Polymorphisms

    Article • Genome Biology and Evolution, September 2013, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  107. Phylogeny and phenotypes of clinical and environmental S higa toxin‐producing E scherichia coli<...

    Article • Environmental Microbiology, August 2013, Wiley

    Prof. Dr. Alexander Mellmann

  108. Lability of the pAA Virulence Plasmid in Escherichia coli O104:H4: Implications for Virulence in Humans

    Article • PLOS One, June 2013, PLOS

    Prof. Dr. Alexander Mellmann

  109. High burden of extended-spectrum  -lactamase-producing Enterobacteriaceae in Gabon

    Article • Journal of Antimicrobial Chemotherapy, May 2013, Oxford University Press (OUP)

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  110. Updating benchtop sequencing performance comparison

    Article • Nature Biotechnology, April 2013, Nature

    Fritz Sedlazeck, Prof. Dr. Alexander Mellmann

  111. Phylogenetic and Molecular Analysis of Food-Borne Shiga Toxin-Producing Escherichia coli

    Article • Applied and Environmental Microbiology, February 2013, ASM Journals

    Prof. Dr. Alexander Mellmann

  112. Livestock-Associated Methicillin-Resistant Staphylococcus aureus (MRSA) as Causes of Human Infection and Colonization in Germany

    Article • PLOS One, February 2013, PLOS

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  113. Enterohemorrhagic Escherichia coli O26:H11/H−: A New Virulent Clone Emerges in Europe

    Article • Clinical Infectious Diseases, February 2013, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  114. Point Mutations in FimH Adhesin of Crohn's Disease-Associated Adherent-Invasive Escherichia coli Enhance Intestinal Inflammatory Response

    Article • PLoS Pathogens, January 2013, PLOS

    Prof. Dr. Alexander Mellmann

  115. Detection of a phylogenetically distinct IMP-type metallo- -lactamase, IMP-35, in a CC235 Pseudomonas aeruginosa from the Dutch-German border region (Euregio)

    Article • Journal of Antimicrobial Chemotherapy, January 2013, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  116. Evaluation of Multiple-Locus Variable Number of Tandem Repeats Analysis for Typing Livestock-Associated Methicillin-Resistant Staphylococcus aureus

    Article • PLOS One, January 2013, PLOS

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  117. Staphylococcal disease in Africa: another neglected ‘tropical’ disease

    Article • Future Microbiology, January 2013, Future Medicine

    Prof. Dr. Alexander Mellmann

  118. Evolution und Infektionsbiologie der mit dem hämolytisch-urämischen Syndrom (HUS) assoziierten E.  coli (HUSEC)

    Article • Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, December 2012, Springer Science + Business Media

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  119. Hygiene in der Radiologie: Was der Radiologe wissen sollte

    Article • RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren, November 2012, Thieme Publishing Group

    Prof. Dr. Alexander Mellmann

  120. Effizientes MRSA-Management

    Article • Der Kardiologe, November 2012, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  121. Clonal structure of Staphylococcus aureus colonizing children with sickle cell anaemia and healthy controls

    Article • Epidemiology and Infection, October 2012, Cambridge University Press

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  122. From Infection to Detection: Imaging S. aureus – host interactions

    Article • Biomedical Engineering / Biomedizinische Technik, August 2012, De Gruyter

    Prof. Dr. Alexander Mellmann

  123. MALDI-TOF Mass Spectrometry-Based Microbial Identification

    Article • August 2012, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  124. Population Dynamics among Methicillin-Resistant Staphylococcus aureus Isolates in Germany during a 6-Year Period

    Article • Journal of Clinical Microbiology, July 2012, ASM Journals

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  125. Multicenter Evaluation of a Sequence-Based Protocol for Subtyping Shiga Toxins and Standardizing Stx Nomenclature

    Article • Journal of Clinical Microbiology, July 2012, ASM Journals

    Prof. Dr. Alexander Mellmann

  126. Towards 3D modelling and imaging of infection scenarios at the single cell level using holographic optical tweezers and digital holographic microscopy

    Article • Journal of Biophotonics, June 2012, Wiley

    Prof. Dr. Alexander Mellmann

  127. Identification of Intermediate in Evolutionary Model of EnterohemorrhagicEscherichia coliO157

    Article • Emerging Infectious Diseases, April 2012, Centers for Disease Control and Prevention (CDC)

    Prof. Dr. Alexander Mellmann

  128. Effects of Antibiotics on Shiga Toxin 2 Production and Bacteriophage Induction by Epidemic Escherichia coli O104:H4 Strain

    Article • Antimicrobial Agents and Chemotherapy, March 2012, ASM Journals

    Prof. Dr. Alexander Mellmann

  129. Real-Time Multiplex PCR for Detecting Shiga Toxin 2-Producing Escherichia coli O104:H4 in Human Stools

    Article • Journal of Clinical Microbiology, February 2012, ASM Journals

    Prof. Dr. Alexander Mellmann

  130. Effizientes MRSA-Management

    Article • Zeitschrift für Herz- Thorax- und Gefäßchirurgie, January 2012, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  131. MRSA eradication in dermatologic outpatients - theory and practice

    Article • JDDG Journal der Deutschen Dermatologischen Gesellschaft, December 2011, Wiley

    Prof. Dr. Alexander Mellmann

  132. Highly divergent Staphylococcus aureus isolates from African non-human primates

    Article • Environmental Microbiology Reports, December 2011, Wiley

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  133. Comparison of Asymptomatic Bacteriuria Escherichia coli Isolates from Healthy Individuals versus Those from Hospital Patients Shows that Long-Term Bladder Colonization Selects for Attenuated Virulence Phenotypes

    Article • Infection and Immunity, November 2011, ASM Journals

    Professor Ulrich Dobrindt, Prof. Dr. Alexander Mellmann

  134. Synergistic Adaptive Mutations in the Hemagglutinin and Polymerase Acidic Protein Lead to Increased Virulence of Pandemic 2009 H1N1 Influenza A Virus in Mice

    Article • The Journal of Infectious Diseases, November 2011, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  135. Virulence factors and genotypes of Staphylococcus aureus from infection and carriage in Gabon

    Article • Clinical Microbiology and Infection, October 2011, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  136. Characterisation of the Escherichia coli strain associated with an outbreak of haemolytic uraemic syndrome in Germany, 2011: a microbiological study

    Article • The Lancet Infectious Diseases, September 2011, Elsevier

    Prof. Dr. Alexander Mellmann

  137. Comparison of Multilocus Variable-Number Tandem-Repeat Analysis and Multilocus Sequence Typing for Differentiation of Hemolytic-Uremic Syndrome-Associated Escherichia coli (HUSEC) Collection Strains

    Article • Journal of Clinical Microbiology, August 2011, ASM Journals

    Prof. Dr. Alexander Mellmann

  138. Automatic MDCT Injectors: Hygiene and Efficiency of Disposable, Prefilled, and Multidosing Roller Pump Systems in Clinical Routine

    Article • American Journal of Roentgenology, August 2011, American Roentgen Ray Society

    Prof. Dr. Alexander Mellmann

  139. Prospective Genomic Characterization of the German Enterohemorrhagic Escherichia coli O104:H4 Outbreak by Rapid Next Generation Sequencing Technology

    Article • PLOS One, July 2011, PLOS

    Prof. Dr. Alexander Mellmann

  140. Do complement factor H 402Y and C7 M allotypes predispose to (typical) haemolytic uraemic syndrome?

    Article • International Journal of Immunogenetics, June 2011, Wiley

    Prof. Dr. Alexander Mellmann

  141. Characterization of Escherichia coli Strains Isolated from Patients with Diarrhea in São Paulo, Brazil: Identification of Intermediate Virulence Factor Profiles by Multiplex PCR

    Article • Journal of Clinical Microbiology, April 2011, ASM Journals

    Prof. Dr. Alexander Mellmann

  142. Chromosomal instability in enterohaemorrhagic Escherichia coli O157:H7: impact on adherence, tellurite resistance and colony phenotype

    Article • Molecular Microbiology, January 2011, Wiley

    Prof. Dr. Alexander Mellmann, Professor Ulrich Dobrindt

  143. Evolutionary analysis and distribution of type III effector genes in pathogenic Escherichia coli from human, animal and food sources

    Article • Environmental Microbiology, September 2010, Wiley

    Prof. Dr. Alexander Mellmann

  144. EnterohemorrhagicEscherichia coliO26:H11–Associated Hemolytic Uremic Syndrome: Bacteriology and Clinical Presentation

    Article • Seminars in Thrombosis and Hemostasis, September 2010, Thieme Publishing Group

    Prof. Dr. Alexander Mellmann

  145. Distribution and Phylogeny of Immunoglobulin-Binding Protein G in Shiga Toxin-Producing Escherichia coli and Its Association with Adherence Phenotypes

    Article • Infection and Immunity, June 2010, ASM Journals

    Prof. Dr. Alexander Mellmann

  146. Phylogenetic Analysis of EnterohemorrhagicEscherichia coliO157, Germany, 1987–2008

    Article • Emerging Infectious Diseases, April 2010, Centers for Disease Control and Prevention (CDC)

    Prof. Dr. Alexander Mellmann

  147. Comparison of Traditional Phenotypic Identification Methods with Partial 5' 16S rRNA Gene Sequencing for Species-Level Identification of Nonfermenting Gram-Negative Bacilli

    Article • Journal of Clinical Microbiology, February 2010, ASM Journals

    Dr Jim Dunn, Prof. Dr. Alexander Mellmann

  148. Semi-selective broth improves screening for methicillin-resistant Staphylococcus aureus

    Article • Journal of Antimicrobial Chemotherapy, February 2010, Oxford University Press (OUP)

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  149. Microbiologic Contamination and Time Efficiency of Use of Automatic MDCT Injectors With Prefilled Syringes: Results of a Clinical Investigation

    Article • American Journal of Roentgenology, February 2010, American Roentgen Ray Society

    Prof. Dr. Alexander Mellmann

  150. Geographic Distribution of Staphylococcus aureus Causing Invasive Infections in Europe: A Molecular-Epidemiological Analysis

    Article • PLoS Medicine, January 2010, PLOS

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  151. High Interlaboratory Reproducibility of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry-Based Species Identification of Nonfermenting Bacteria

    Article • Journal of Clinical Microbiology, September 2009, ASM Journals

    Prof. Dr. Alexander Mellmann

  152. Phylogeny and Disease Association of Shiga Toxin–producingEscherichia coliO91

    Article • Emerging Infectious Diseases, September 2009, Centers for Disease Control and Prevention (CDC)

    Prof. Dr. Alexander Mellmann

  153. Intrahost Genome Alterations in Enterohemorrhagic Escherichia coli

    Article • Gastroenterology, May 2009, Elsevier

    Prof. Dr. Alexander Mellmann

  154. Shiga Toxin, Cytolethal Distending Toxin, and Hemolysin Repertoires in Clinical Escherichia coli O91 Isolates

    Article • Journal of Clinical Microbiology, April 2009, ASM Journals

    Prof. Dr. Alexander Mellmann

  155. Cross-border comparison of the admission prevalence and clonal structure of meticillin-resistant Staphylococcus aureus

    Article • Journal of Hospital Infection, April 2009, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  156. Phenotypic and Genotypic Traits of Shiga Toxin–Negative E. coli O157:H7/H− Bovine and Porcine Strains

    Article • Foodborne Pathogens and Disease, March 2009, Mary Ann Liebert Inc

    Prof. Dr. Alexander Mellmann

  157. Microbiologic Contamination of Automatic Injectors at MDCT: Experimental and Clinical Investigations

    Article • American Journal of Roentgenology, December 2008, American Roentgen Ray Society

    Prof. Dr. Alexander Mellmann

  158. Detection and Characterization of the Fimbrial sfp Cluster in Enterohemorrhagic Escherichia coli O165:H25/NM Isolates from Humans and Cattle

    Article • Applied and Environmental Microbiology, October 2008, ASM Journals

    Prof. Dr. Alexander Mellmann

  159. Lack of Evidence for "Acinetobacter septicus" as a Species Different from Acinetobacter ursingii?

    Article • Journal of Clinical Microbiology, August 2008, ASM Journals

    Prof. Dr. Alexander Mellmann

  160. Analysis of Collection of Hemolytic Uremic Syndrome–associated EnterohemorrhagicEscherichia coli

    Article • Emerging Infectious Diseases, August 2008, Centers for Disease Control and Prevention (CDC)

    Prof. Dr. Alexander Mellmann

  161. Shiga Toxin–Negative Attaching and EffacingEscherichia coli:Distinct Clinical Associations with Bacterial Phylogeny and Virulence Traits and Inferred In‐Host Pathogen Evolution

    Article • Clinical Infectious Diseases, July 2008, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  162. Characterization of Clonal Relatedness among the Natural Population of Staphylococcus aureus Strains by Using spa Sequence Typing and the BURP (Based upon Repeat Patterns) Algorithm

    Article • Journal of Clinical Microbiology, June 2008, ASM Journals

    Prof. Dr. Alexander Mellmann

  163. Evaluation of Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry in Comparison to 16S rRNA Gene Sequencing for Species Identification of Nonfermenting Bacteria

    Article • Journal of Clinical Microbiology, April 2008, ASM Journals

    Dr Jim Dunn, Prof. Dr. Alexander Mellmann

  164. Evidence for cost reduction based on pre-admission MRSA screening in general surgery

    Article • International Journal of Hygiene and Environmental Health, March 2008, Elsevier

    Prof. Dr. Alexander Mellmann

  165. Acinetobacter septicus sp. nov. Association with a Nosocomial Outbreak of Bacteremia in a Neonatal Intensive Care Unit

    Article • Journal of Clinical Microbiology, December 2007, ASM Journals

    Prof. Dr. Alexander Mellmann

  166. Recycling of Shiga Toxin 2 Genes in Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:NM

    Article • Applied and Environmental Microbiology, November 2007, ASM Journals

    Prof. Dr. Alexander Mellmann

  167. Shiga Toxin-Mediated Hemolytic Uremic Syndrome: Time to Change the Diagnostic Paradigm?

    Article • PLOS One, October 2007, PLOS

    Prof. Dr. Alexander Mellmann

  168. Subtypes of the Plasmid-Encoded Serine Protease EspP in Shiga Toxin-Producing Escherichia coli: Distribution, Secretion, and Proteolytic Activity

    Article • Applied and Environmental Microbiology, August 2007, ASM Journals

    Prof. Dr. Alexander Mellmann

  169. Distribution of capsular and surface polysaccharide serotypes of Staphylococcus aureus

    Article • Diagnostic Microbiology and Infectious Disease, July 2007, Elsevier

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  170. Staphylococcus pettenkoferi sp. nov., a novel coagulase-negative staphylococcal species isolated from human clinical specimens

    Article • INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, July 2007, Society for General Microbiology

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  171. Prevalence, Virulence Profiles, and Clinical Significance of Shiga Toxin-Negative Variants of Enterohemorrhagic Escherichia coli O157 Infection in Humans

    Article • Clinical Infectious Diseases, July 2007, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  172. Staphylococcal Chromosomal Cassette mec Type I, spa Type, and Expression of Pls Are Determinants of Reduced Cellular Invasiveness of Methicillin‐Resistant Staphylococcus aureus Isolates

    Article • The Journal of Infectious Diseases, June 2007, Oxford University Press (OUP)

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  173. Shiga Toxin Gene Loss and Transfer In Vitro and In Vivo during Enterohemorrhagic Escherichia coli O26 Infection in Humans

    Article • Applied and Environmental Microbiology, March 2007, ASM Journals

    Prof. Dr. Alexander Mellmann

  174. Structural and functional differences between disease-associated genes of enterohaemorrhagic Escherichia coli O111

    Article • International Journal of Medical Microbiology, February 2007, Elsevier

    Prof. Dr. Alexander Mellmann

  175. Based Upon Repeat Pattern (BURP): an algorithm to characterize the long-term evolution of Staphylococcus aureus populations based on spa polymorphisms

    Article • BMC Microbiology, January 2007, Springer Science + Business Media

    Prof. Dr. Alexander Mellmann

  176. EUREGIO-Projekt MRSA-net Twente/Münsterland

    Article • Das Gesundheitswesen, November 2006, Thieme Publishing Group

    Prof. Dr. Alexander Mellmann

  177. Urease genes in non-O157 Shiga toxin-producing Escherichia coli: mostly silent but valuable markers for pathogenicity

    Article • Clinical Microbiology and Infection, May 2006, Elsevier

    Prof. Dr. Alexander Mellmann

  178. Chromosomal Dynamism in Progeny of Outbreak-Related Sorbitol-Fermenting Enterohemorrhagic Escherichia coli O157:NM

    Article • Applied and Environmental Microbiology, March 2006, ASM Journals

    Prof. Dr. Alexander Mellmann

  179. High Interlaboratory Reproducibility of DNA Sequence-Based Typing of Bacteria in a Multicenter Study

    Article • Journal of Clinical Microbiology, February 2006, ASM Journals

    Prof. Dr. Alexander Mellmann

  180. Automated DNA Sequence-Based Early Warning System for the Detection of Methicillin-Resistant Staphylococcus aureus Outbreaks

    Article • PLoS Medicine, January 2006, PLOS

    Prof. Dr. Alexander Mellmann

  181. Ridom TraceEdit: a DNA trace editor and viewer

    Article • Bioinformatics, December 2005, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  182. Shiga Toxin 2e-Producing Escherichia coli Isolates from Humans and Pigs Differ in Their Virulence Profiles and Interactions with Intestinal Epithelial Cells

    Article • Applied and Environmental Microbiology, December 2005, ASM Journals

    Prof. Dr. Alexander Mellmann

  183. Enterohemorrhagic Escherichia coli in Human Infection: In Vivo Evolution of a Bacterial Pathogen

    Article • Clinical Infectious Diseases, September 2005, Oxford University Press (OUP)

    Prof. Dr. Alexander Mellmann

  184. Evidenzbasierte Hygienemaßnahmen mittelsspa-Typisierung bei MRSA-Häufungen im Krankenhaus

    Article • DMW - Deutsche Medizinische Wochenschrift, June 2005, Thieme Publishing Group

    Prof. Dr. Alexander Mellmann

  185. Variation of the Polymorphic Region X of the Protein A Gene during Persistent Airway Infection of Cystic Fibrosis Patients Reflects Two Independent Mechanisms of Genetic Change in Staphylococcus aureus

    Article • Journal of Clinical Microbiology, January 2005, ASM Journals

    Prof. Dr. Alexander Mellmann

  186. Development and Evaluation of a Quality-Controlled Ribosomal Sequence Database for 16S Ribosomal DNA-Based Identification of Staphylococcus Species

    Article • Journal of Clinical Microbiology, November 2004, ASM Journals

    Prof. Dr. med. Karsten Becker, Prof. Dr. Alexander Mellmann

  187. Phylogeny, Clinical Associations, and Diagnostic Utility of the Pilin Subunit Gene (sfpA) of Sorbitol-Fermenting, Enterohemorrhagic Escherichia coli O157:H-

    Article • Journal of Clinical Microbiology, October 2004, ASM Journals

    Prof. Dr. Alexander Mellmann

  188. Sequence-Based Typing of flaB Is a More Stable Screening Tool Than Typing of flaA for Monitoring of Campylobacter Populations

    Article • Journal of Clinical Microbiology, October 2004, ASM Journals

    Prof. Dr. Alexander Mellmann

  189. Evaluation of RIDOM, MicroSeq, and GenBank services in the molecular identification of Nocardia species

    Article • International Journal of Medical Microbiology, January 2003, Elsevier

    Prof. Dr. Alexander Mellmann

  190. Nosocomial cross transmission as a primary cause of vancomycin-resistant enterococci in Austria

    Article • Journal of Hospital Infection, April 2000, Elsevier

    Prof. Dr. Alexander Mellmann