All Stories

  1. Time to diagnosis and long-term outcomes for adults presenting with breathlessness

    Article • Thorax, November 2025, BMJ

    Prof Alex Bottle

  2. Breathlessness intensity recorded in general practice is associated with shorter times to unplanned hospital admissions and longer lengths of stay: a UK cohort study

    Article • BMJ Open Respiratory Research, July 2025, BMJ

    Prof Alex Bottle

  3. Patterns of online consultation use in Great Britain, 2019–2023: an observational analysis

    Article • BMJ Digital Health & AI, July 2025, BMJ

    Prof Alex Bottle

  4. Non-adherence to medications prescribed to patients with heart failure in general practice: prevalence, risk factors and association with mortality and hospitalisation

    Article • Open Heart, July 2025, BMJ

    Prof Alex Bottle

  5. Association Between Surgeon Volume and Patient Outcomes After Elective Patellofemoral Arthroplasty

    Article • Journal of Bone and Joint Surgery, February 2025, Wolters Kluwer Health

    Prof Alex Bottle

  6. Is geographical variation in emergency epilepsy admissions related to variation in new epilepsy diagnoses among children and young people across England? An observational study using linked datasets

    Article • BMJ Open, February 2025, BMJ

    Prof Alex Bottle

  7. GP consultations for respiratory tract infections in children aged <5 years: a retrospective cohort study 2016–2023

    Article • British Journal of General Practice, December 2024, Royal College of General Practitioners

    Prof Alex Bottle

  8. The Impact of COVID-19 on Acute Surgeries in England Among the Under-25s: A Retrospective Study of 61,360 Appendicitis and 15,850 Testicular Torsion Admissions

    Article • Journal of Pediatric Surgery, December 2024, Elsevier

    Prof Alex Bottle

  9. What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey

    Article • Health and Social Care Delivery Research, October 2024, National Institute for Health Research

    Prof Alex Bottle

  10. Incidence of rectal cancer after colectomy for inflammatory bowel disease: nationwide study

    Article • BJS Open, September 2024, Oxford University Press (OUP)

    Prof Alex Bottle

  11. GenAI Exceeds Clinical Experts in Predicting Acute Kidney Injury following Paediatric Cardiopulmonary Bypass2

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Prof Alex Bottle, Dr Richard W Issitt

  12. The impact of the COVID-19 pandemic on 397 631 elective dental admissions among the under-25s in England: a retrospective study

    Article • Journal of Public Health, May 2024, Oxford University Press (OUP)

    Prof Alex Bottle

  13. Associations between prior healthcare use, time to diagnosis, and clinical outcomes in inflammatory bowel disease: a nationally representative population-based cohort study

    Article • BMJ Open Gastroenterology, May 2024, BMJ

    Prof Alex Bottle

  14. Exploration of understanding of impactibility analysis and application through workshops to inform model design for population health management policy: a qualitative assessment

    Article • BMJ Open, May 2024, BMJ

    Prof Alex Bottle

  15. Variation in quality of care between hospitals: how to identify learning opportunities

    Article • BMJ Quality & Safety, March 2024, BMJ

    Prof Alex Bottle

  16. Time to diagnosis and long-term outcomes for adults presenting with breathlessness

    Article • February 2024, Cold Spring Harbor Laboratory Press

    Prof Alex Bottle

  17. Impact of the COVID-19 pandemic on the clinical management trends for acute appendicitis among the under-25s: a retrospective study

    Article • Archives of Disease in Childhood, February 2024, BMJ

    Prof Alex Bottle

  18. Evaluation of emergency hospital admissions for inflammatory bowel disease as a possible marker of quality of care of British IBD inflammatory bowel disease units

    Article • Frontline Gastroenterology, January 2024, BMJ

    Prof Alex Bottle

  19. Adherence to 5-aminosalicylic acid maintenance treatment in young people with ulcerative colitis: a retrospective cohort study in primary care

    Article • British Journal of General Practice, June 2023, Royal College of General Practitioners

    Prof Alex Bottle

  20. Systematic review with meta‐analysis: Time to diagnosis and the impact of delayed diagnosis on clinical outcomes in inflammatory bowel disease

    Article • Alimentary Pharmacology & Therapeutics, January 2023, Wiley

    Prof Alex Bottle

  21. Hip fracture in the COVID-19 era: what can we say about care and patient outcomes?

    Article • BMJ Quality & Safety, December 2022, BMJ

    Prof Alex Bottle

  22. Risk prediction of mortality for patients with heart failure in England: observational study in primary care

    Article • ESC Heart Failure, November 2022, Wiley

    Prof Alex Bottle

  23. Impact of COVID-19 on outpatient appointments in children and young people in England: an observational study

    Article • BMJ Open, August 2022, BMJ

    Prof Alex Bottle

  24. Factors associated with, and variations in, COVID-19 hospital death rates in England’s first two waves: observational study

    Article • BMJ Open, June 2022, BMJ

    Prof Alex Bottle

  25. Impact of COVID-19 on primary care contacts with children and young people in England: longitudinal trends study 2015–2020

    Article • British Journal of General Practice, April 2022, Royal College of General Practitioners

    Prof Alex Bottle

  26. Antidepressant medication use in Inflammatory Bowel Disease: a nationally representative population‐based study

    Article • Alimentary Pharmacology & Therapeutics, March 2022, Wiley

    Prof Alex Bottle

  27. Changes in heart failure management and long-term mortality over 10 years: observational study

    Article • Open Heart, March 2022, BMJ

    Prof Alex Bottle

  28. Bridging the impactibility gap in population health management: a systematic review

    Article • BMJ Open, December 2021, BMJ

    Prof Alex Bottle

  29. Socioeconomic deprivation and ethnicity inequalities in disruption to NHS hospital admissions during the COVID-19 pandemic: a national observational study

    Article • BMJ Quality & Safety, November 2021, BMJ

    Prof Alex Bottle

  30. Outsourcing care to the private sector: some reassuring evidence on patient outcomes

    Article • BMJ Quality & Safety, October 2021, BMJ

    Prof Alex Bottle

  31. Stability over time of the “hospital effect” on 30-day unplanned readmissions: Evidence from administrative data

    Article • Health Policy, October 2021, Elsevier

    Prof Alex Bottle

  32. Competing risks in quality and safety research: a framework to guide choice of analysis and improve reporting

    Article • BMJ Quality & Safety, September 2021, BMJ

    Prof Alex Bottle

  33. Patient-level and hospital-level variation and related time trends in COVID-19 case fatality rates during the first pandemic wave in England: multilevel modelling analysis of routine data

    Article • BMJ Quality & Safety, July 2021, BMJ

    Prof Alex Bottle

  34. Online application for self-referral of the patients with breast symptoms

    Article • Annals of Medicine and Surgery, June 2021, Wolters Kluwer Health

    Prof Alex Bottle

  35. Association between antidepressant medication use and steroid dependency in patients with ulcerative colitis: a population-based study

    Article • BMJ Open Gastroenterology, May 2021, BMJ

    Prof Alex Bottle

  36. Five-year outcomes following left ventricular assist device implantation in England

    Article • Open Heart, May 2021, BMJ

    Prof Alex Bottle

  37. CCopeY: A Mixed-Methods Coproduced Study on the Mental Health Status and Coping Strategies of Young People During COVID-19 UK Lockdown

    Article • Journal of Adolescent Health, April 2021, Elsevier

    Prof Alex Bottle

  38. COPD: still an unpredictable journey

    Article • European Respiratory Journal, March 2021, European Respiratory Society (ERS)

    Prof Alex Bottle

  39. Periprosthetic fractures: the next fragility fracture epidemic? A national observational study

    Article • BMJ Open, December 2020, BMJ

    Prof Alex Bottle

  40. Characteristics of frequent paediatric users of emergency departments in England: an observational study using routine national data

    Article • Emergency Medicine Journal, November 2020, BMJ

    Prof Alex Bottle

  41. Depression in individuals who subsequently develop inflammatory bowel disease: a population-based nested case–control study

    Article • Gut, October 2020, BMJ

    Prof Alex Bottle

  42. Stage at Diagnosis and Survival of Colorectal Cancer With or Without Underlying Inflammatory Bowel Disease: A Population-based Study

    Article • Journal of Crohn s and Colitis, September 2020, Oxford University Press (OUP)

    Prof Alex Bottle

  43. Impact of a pay-for-performance scheme for long-acting reversible contraceptive (LARC) advice on contraceptive uptake and abortion in British primary care: An interrupted time series study

    Article • PLoS Medicine, September 2020, PLOS

    Prof Alex Bottle

  44. How an electronic health record became a real-world research resource: comparison between London’s Whole Systems Integrated Care database and the Clinical Practice Research Datalink

    Article • BMC Medical Informatics and Decision Making, April 2020, Springer Science + Business Media

    Prof Alex Bottle

  45. Frequent attendances at emergency departments in England

    Article • Emergency Medicine Journal, April 2020, BMJ

    Prof Alex Bottle

  46. Protocol for developing a core outcome set for evaluating school-based physical activity interventions in primary schools

    Article • BMJ Open, December 2019, BMJ

    Prof Alex Bottle

  47. The impact of smoking and smoking cessation on disease outcomes in ulcerative colitis: a nationwide population‐based study

    Article • Alimentary Pharmacology & Therapeutics, August 2019, Wiley

    Prof Alex Bottle

  48. Risk factors for early revision after total hip and knee arthroplasty: National observational study from a surgeon and population perspective

    Article • PLOS One, April 2019, PLOS

    Prof Alex Bottle

  49. Predictors of 30-Day Readmission After Total Knee Arthroplasty: Analysis of 566,323 Procedures in the United Kingdom

    Article • The Journal of Arthroplasty, February 2019, Elsevier

    Prof Alex Bottle

  50. American Heart Association’s Cholesterol CarePlan as a Smartphone-Delivered Web App for Patients Prescribed Cholesterol-Lowering Medication: Protocol for an Observational Feasibility Study

    Article • JMIR Research Protocols, January 2019, JMIR Publications Inc.

    Prof Alex Bottle

  51. Frailty and co-morbidity predict first hospitalisation after heart failure diagnosis in primary care: population-based observational study in England

    Article • Age and Ageing, January 2019, Oxford University Press (OUP)

    Prof Alex Bottle

  52. Real-world presentation with heart failure in primary care: do patients selected to follow diagnostic and management guidelines have better outcomes?

    Article • Open Heart, November 2018, BMJ

    Prof Alex Bottle

  53. Trajectory Modelling to Assess Trends in Long-Term Readmission Rate among Abdominal Aortic Aneurysm Patients

    Article • Surgery Research and Practice, October 2018, Hindawi Publishing Corporation

    Prof Alex Bottle

  54. National hospital mortality surveillance system: a descriptive analysis

    Article • BMJ Quality & Safety, October 2018, BMJ

    Prof Alex Bottle

  55. Common Sequences of Emergency Readmissions among High-Impact Users following AAA Repair

    Article • Surgery Research and Practice, July 2018, Hindawi Publishing Corporation

    Prof Alex Bottle

  56. Comparison of 3 Types of Readmission Rates for Measuring Hospital and Surgeon Performance After Primary Total Hip and Knee Arthroplasty

    Article • The Journal of Arthroplasty, July 2018, Elsevier

    Prof Alex Bottle

  57. Factors associated with hospital emergency readmission and mortality rates in patients with heart failure or chronic obstructive pulmonary disease: a national observational study

    Article • Health Services and Delivery Research, July 2018, National Institute for Health Research

    Prof Alex Bottle

  58. Investigating the association of alerts from a national mortality surveillance system with subsequent hospital mortality in England: an interrupted time series analysis

    Article • BMJ Quality & Safety, May 2018, BMJ

    Prof Alex Bottle

  59. American Heart Association’s Cholesterol CarePlan as a Smartphone-Delivered Web App for Patients Prescribed Cholesterol-Lowering Medication: Protocol for an Observational Feasibility Study (Preprint)

    Article • February 2018, JMIR Publications Inc.

    Prof Alex Bottle

  60. Evaluation of a national surveillance system for mortality alerts: a mixed-methods study

    Article • Health Services and Delivery Research, February 2018, National Institute for Health Research

    Prof Alex Bottle

  61. Retrospective analysis of the national impact of industrial action by English junior doctors in 2016

    Article • BMJ Open, January 2018, BMJ

    Prof Alex Bottle

  62. Reorganisation of stroke care and impact on mortality in patients admitted during weekends: a national descriptive study based on administrative data

    Article • BMJ Quality & Safety, October 2017, BMJ

    Prof Alex Bottle

  63. Secondary analysis of hospital patient experience scores across England’s National Health Service – How much has improved since 2005?

    Article • PLOS One, October 2017, PLOS

    Prof Alex Bottle

  64. How and where do patients get their diagnosis of heart failure in England?

    Article • Heart, October 2017, BMJ

    Prof Alex Bottle

  65. What patient factors predict emergency hospital readmission after hip replacement?

    Article • JAMA Surgery, October 2017, American Medical Association (AMA)

    Prof Alex Bottle

  66. Nation-wide trends in non-alcoholic steatohepatitis (NASH) in patients with and without diabetes between 2004–05 and 2014–15 in England

    Article • Diabetes Research and Clinical Practice, October 2017, Elsevier

    Prof Alex Bottle

  67. ISQUA17-1421COMPARISON OF HOSPITALISATION AND MORTALITY FOR PATIENTS WITH HEART FAILURE IN ENGLAND AND LOMBARDY REGION (NORTHERN ITALY)

    Article • International Journal for Quality in Health Care, September 2017, Oxford University Press (OUP)

    Prof Alex Bottle

  68. ISQUA17-1767ARE MORTALITY ALERTS ASSOCIATED WITH OTHER INDICATORS OF HOSPITAL QUALITY IN ENGLAND? A NATIONAL CROSS-SECTIONAL STUDY

    Article • International Journal for Quality in Health Care, September 2017, Oxford University Press (OUP)

    Prof Alex Bottle

  69. The Risk of Adverse Pregnancy Outcomes Following Nonobstetric Surgery During Pregnancy

    Article • Annals of Surgery, August 2017, Wolters Kluwer Health

    Prof Alex Bottle

  70. Does early return to theatre add value to rates of revision at 3 years in assessing surgeon performance for elective hip and knee arthroplasty? National observational study

    Article • BMJ Quality & Safety, August 2017, BMJ

    Prof Alex Bottle

  71. Regional variation in hospitalisation and mortality in heart failure: comparison of England and Lombardy using multistate modelling

    Article • Health Care Management Science, July 2017, Springer Science + Business Media

    Prof Alex Bottle

  72. A retrospective cohort study of high-impact users among patients with cerebrovascular conditions

    Article • BMJ Open, June 2017, BMJ

    Prof Alex Bottle

  73. 5 The relation between length of stay, a&e attendance and readmission for heart failure patients

    Article • Heart, June 2017, BMJ

    Prof Alex Bottle

  74. Investigating Adverse Event Free Admissions in Medicare Inpatients as a Patient Safety Indicator

    Article • Annals of Surgery, May 2017, Wolters Kluwer Health

    Prof Alex Bottle

  75. The relationship between ethnicity, social deprivation and late presentation of colorectal cancer

    Article • Cancer Epidemiology, April 2017, Elsevier

    Prof Alex Bottle

  76. Main reasons for readmissions over time among stroke patients

    Article • Stroke Research and Treatment, January 2017, Hindawi Publishing Corporation

    Prof Alex Bottle

  77. Alex Bottle, Paul Aylin: Statistical methods for healthcare performance monitoring

    Article • Statistical Papers, October 2016, Springer Science + Business Media

    Prof Alex Bottle

  78. ISQUA16-2316IS THERE A RELATIONSHIP BETWEEN EARLY UNPLANNED RETURN TO THEATRE AND THREE-YEAR REVISION RATES FOR ELECTIVE HIP AND KNEE REPLACEMENT SURGERY?

    Article • International Journal for Quality in Health Care, October 2016, Oxford University Press (OUP)

    Prof Alex Bottle

  79. ISQUA16-2703THE ASSOCIATION BETWEEN WEEKEND/WEEKDAY IN-HOSPITAL MORTALITY AND CENTRALISATION OF STROKE SERVICES

    Article • International Journal for Quality in Health Care, October 2016, Oxford University Press (OUP)

    Prof Alex Bottle

  80. Does laminar flow ventilation reduce the rate of infection?: an observational study of trauma in England

    Article • The Bone & Joint Journal, September 2016, Bone & Joint

    Prof Alex Bottle

  81. Defining the timing and causes of death amongst patients undergoing colorectal resection in England

    Article • Colorectal Disease, June 2016, Wiley

    Prof Alex Bottle

  82. Use of hospital services by age and comorbidity after an index heart failure admission in England: an observational study

    Article • BMJ Open, June 2016, BMJ

    Prof Alex Bottle

  83. Surgeon Volume and Cancer Esophagectomy, Gastrectomy, and Pancreatectomy

    Article • Annals of Surgery, April 2016, Wolters Kluwer Health

    Prof Alex Bottle

  84. Mo1149 Wide Variation in Resection Rates and Survival in Elderly Colorectal Cancer Patients in England

    Article • Gastroenterology, April 2016, Elsevier

    Prof Alex Bottle

  85. Association Between Day of Delivery and Obstetric Outcomes

    Article • Obstetrical & Gynecological Survey, March 2016, Wolters Kluwer Health

    Prof Alex Bottle

  86. Stroke Severity Is a Crucial Predictor of Outcome: An International Prospective Validation Study

    Article • Journal of the American Heart Association, January 2016, Wolters Kluwer Health

    Prof Alex Bottle

  87. Multi-Morbidity in Hospitalised Older Patients: Who Are the Complex Elderly?

    Article • PLOS One, December 2015, PLOS

    Prof Alex Bottle

  88. Risk of Post-Discharge Venous Thromboembolism and Associated Mortality in General Surgery: A Population-Based Cohort Study Using Linked Hospital and Primary Care Data in England

    Article • PLOS One, December 2015, PLOS

    Prof Alex Bottle

  89. Association between day of delivery and obstetric outcomes: observational study

    Article • BMJ, November 2015, BMJ

    Prof Alex Bottle

  90. Linked Hospital and Primary Care Database Analysis of the Incidence and Impact of Psychiatric Morbidity Following Gastrointestinal Cancer Surgery in England

    Article • Annals of Surgery, November 2015, Wolters Kluwer Health

    Prof Alex Bottle

  91. Additive impact of pneumococcal conjugate vaccines on pneumonia and empyema hospital admissions in England

    Article • Journal of Infection, October 2015, Elsevier

    Prof Alex Bottle

  92. Lack of Engagement in Surgical Quality Improvement Research Is Associated with Poorer Quality of Care

    Article • Journal of the American College of Surgeons, October 2015, Elsevier

    Prof Alex Bottle

  93. Monitoring patient safety in primary care: an exploratory study using in-depth semistructured interviews: Table 1

    Article • BMJ Open, September 2015, BMJ

    Prof Alex Bottle

  94. Trends in Immediate Postmastectomy Breast Reconstruction in the United Kingdom

    Article • Plastic and Reconstructive Surgery Global Open, September 2015, Wolters Kluwer Health

    Prof Alex Bottle

  95. Exploring the impact of consultants’ experience on hospital mortality by day of the week: a retrospective analysis of hospital episode statistics 

    Article • BMJ Quality & Safety, July 2015, BMJ

    Prof Alex Bottle

  96. The Global Comparators project: international comparison of 30-day in-hospital mortality by day of the week

    Article • BMJ Quality & Safety, July 2015, BMJ

    Prof Alex Bottle

  97. Evaluation of a continuous monitoring and feedback initiative to improve quality of anaesthetic care: a mixed-methods quasi-experimental study

    Article • Health Services and Delivery Research, July 2015, National Institute for Health Research

    Prof Alex Bottle

  98. Relation between process measures and diagnosis-specific readmission rates in patients with heart failure

    Article • Heart, June 2015, BMJ

    Prof Alex Bottle

  99. The effect of medications to prevent blood clots after hip and knee replacement

    Article • Arthroplasty Today, June 2015, Elsevier

    Prof Alex Bottle

  100. PTU-269 Lack of engagement in surgical quality improvement research is associated with poorer quality of care

    Article • Gut, June 2015, BMJ

    Prof Alex Bottle

  101. The “Friday effect”: Can epidemiology tell us when to operate?

    Article • Canadian Journal of Anesthesia/Journal canadien d anesthésie, May 2015, Springer Science + Business Media

    Prof Alex Bottle

  102. Understanding how colorectal units achieve short length of stay: an interview survey among representative hospitals in England

    Article • Patient Safety in Surgery, January 2015, Springer Science + Business Media

    Prof Alex Bottle

  103. The US hospital standardised mortality ratio: Retrospective database study of Massachusetts hospitals

    Article • JRSM Open, January 2015, SAGE Publications

    Prof Alex Bottle

  104. Arthroplasty return to theatre

    Article • The Bone & Joint Journal, December 2014, Bone & Joint

    Prof Alex Bottle

  105. Can valid and practical risk-prediction or casemix adjustment models, including adjustment for comorbidity, be generated from English hospital administrative data (Hospital Episode Statistics)? A national observational study

    Article • Health Services and Delivery Research, November 2014, National Institute for Health Research

    Prof Alex Bottle

  106. Changing Indications and Socio-Demographic Determinants of (Adeno)Tonsillectomy among Children in England – Are They Linked? A Retrospective Analysis of Hospital Data

    Article • PLOS One, August 2014, PLOS

    Prof Alex Bottle

  107. Effect of the readmission primary diagnosis and time interval in heart failure patients: analysis of English administrative data

    Article • European Journal of Heart Failure, July 2014, Wiley

    Prof Alex Bottle

  108. Preoperative Risk Factors in 10,418 Patients With Prior Myocardiac Infarction and 5241 Patients With Previous Unstable Angina Undergoing Elective Coronary Artery Bypass Graft Surgery

    Article • Survey of Anesthesiology, June 2014, Wolters Kluwer Health

    Prof Alex Bottle

  109. Assessment of abdominoperineal resection rate as a surrogate marker of hospital quality in rectal cancer surgery (Br J Surg 2013; 100: 1655–1663)

    Article • BJS, April 2014, Oxford University Press (OUP)

    Prof Alex Bottle

  110. Classifying Hospitals as Mortality Outliers: Logistic Versus Hierarchical Logistic Models

    Article • Journal of Medical Systems, April 2014, Springer Science + Business Media

    Prof Alex Bottle

  111. Risk Factors for Hospital Admission with RSV Bronchiolitis in England: A Population-Based Birth Cohort Study

    Article • PLOS One, February 2014, PLOS

    Prof Alex Bottle

  112. Classifier calibration using splined empirical probabilities in clinical risk prediction

    Article • Health Care Management Science, February 2014, Springer Science + Business Media

    Prof Alex Bottle

  113. Preoperative Stroke and Outcomes After Coronary Artery Bypass Graft Surgery

    Article • Survey of Anesthesiology, February 2014, Wolters Kluwer Health

    Prof Alex Bottle

  114. Care is needed in epidemiological research not to overgeneralise about cancer diagnosis and treatment

    Article • BMJ, December 2013, BMJ

    Prof Alex Bottle

  115. A national analysis of the outcome of major head and neck cancer surgery: implications for surgeon-level data publication

    Article • Clinical Otolaryngology, December 2013, Wiley

    Prof Alex Bottle

  116. Current ICD10 codes are insufficient to clearly distinguish acute myocardial infarction type: a descriptive study

    Article • BMC Health Services Research, November 2013, Springer Science + Business Media

    Prof Alex Bottle

  117. Have contractual changes in primary care affected unplanned short stay childhood admissions in England? National time trends study 2001–11

    Article • The Lancet, November 2013, Elsevier

    Prof Alex Bottle

  118. The role of caseload in determining outcome following laparoscopic colorectal cancer resection: an observational study

    Article • Surgical Endoscopy, September 2013, Springer Science + Business Media

    Prof Alex Bottle

  119. Hierarchical multilevel analysis of increased caseload volume and postoperative outcome after elective colorectal surgery

    Article • BJS, September 2013, Wiley

    Prof Alex Bottle

  120. Provider profiling models for acute coronary syndrome mortality using administrative data

    Article • International Journal of Cardiology, September 2013, Elsevier

    Prof Alex Bottle

  121. Predictors of Readmission in Heart Failure Patients Vary by Cause of Readmission: Hospital-Level Cause-Specific Readmission Rates Show No Correlation

    Article • September 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Prof Alex Bottle

  122. The effects of resource availability on mortality for emergency general surgical admissions

    Article • Journal of the American College of Surgeons, September 2013, Elsevier

    Prof Alex Bottle

  123. Cancer diagnosed by emergency admission in England: an observational study using the general practice research database

    Article • BMC Health Services Research, August 2013, Springer Science + Business Media

    Prof Alex Bottle

  124. Adverse events recorded in English primary care: observational study using the General Practice Research Database

    Article • British Journal of General Practice, August 2013, Royal College of General Practitioners

    Prof Alex Bottle

  125. Mortality in high-risk emergency general surgical admissions

    Article • BJS, July 2013, Wiley

    Prof Alex Bottle

  126. Global Comparators Project: International Comparison of Hospital Outcomes Using Administrative Data

    Article • Health Services Research, June 2013, Wiley

    Prof Alex Bottle

  127. A retrospective study of the impact of the doctors’ strike in England on 21 June 2012

    Article • Journal of the Royal Society of Medicine, June 2013, SAGE Publications

    Prof Alex Bottle

  128. Sore throat consultations in general practice prior to tonsillectomy among eight hundred and sixty‐three children in England: is this in accordance with the SIGN guidelines?

    Article • Clinical Otolaryngology, June 2013, Wiley

    Prof Alex Bottle

  129. Day of week of procedure and 30 day mortality for elective surgery: retrospective analysis of hospital episode statistics

    Article • BMJ, May 2013, BMJ

    Prof Alex Bottle

  130. Ethnic group differences in cardiovascular risk assessment scores: national cross-sectional study

    Article • Ethnicity and Health, May 2013, Taylor & Francis

    Prof Alex Bottle

  131. National outcomes and uptake of laparoscopic gastrectomy for cancer in England

    Article • Surgical Endoscopy, April 2013, Springer Science + Business Media

    Prof Alex Bottle

  132. Preoperative risk factors in 10 418 patients with prior myocardial infarction and 5241 patients with prior unstable angina undergoing elective coronary artery bypass graft surgery

    Article • British Journal of Anaesthesia, April 2013, Oxford University Press (OUP)

    Prof Alex Bottle

  133. Meeting the ambition of measuring the quality of hospitals' stroke care using routinely collected administrative data: a feasibility study

    Article • International Journal for Quality in Health Care, April 2013, Oxford University Press (OUP)

    Prof Alex Bottle

  134. Preoperative Stroke and Outcomes after Coronary Artery Bypass Graft Surgery

    Article • Anesthesiology, April 2013, Wolters Kluwer Health

    Prof Alex Bottle

  135. Failure to Rescue Patients After Reintervention in Gastroesophageal Cancer Surgery in England

    Article • JAMA Surgery, March 2013, American Medical Association (AMA)

    Prof Alex Bottle

  136. Staff perceptions of quality of care: an observational study of the NHS Staff Survey in hospitals in England

    Article • BMJ Quality & Safety, February 2013, BMJ

    Prof Alex Bottle

  137. Is “failure to rescue” derived from administrative data in England a nurse sensitive patient safety indicator for surgical care? Observational study

    Article • International Journal of Nursing Studies, February 2013, Elsevier

    Prof Alex Bottle, Prof Peter Griffiths

  138. Weekend Admissions and Increased Risk for Mortality: Less Urgent Treatments Only?—Reply

    Article • JAMA Neurology, January 2013, American Medical Association (AMA)

    Prof Alex Bottle

  139. Systematic Review of Comorbidity Indices for Administrative Data

    Article • Medical Care, December 2012, Wolters Kluwer Health

    Prof Alex Bottle

  140. Minimal-access colorectal surgery is associated with fewer adhesion-related admissions than open surgery

    Article • BJS, November 2012, Wiley

    Prof Alex Bottle

  141. Significantly increasing hospital admissions for acute throat infections among children in England: is this related to tonsillectomy rates?

    Article • Archives of Disease in Childhood, October 2012, BMJ

    Prof Alex Bottle

  142. Dying for the Weekend

    Article • Archives of Neurology, October 2012, American Medical Association (AMA)

    Prof Alex Bottle

  143. Quality of routine hospital birth records and the feasibility of their use for creating birth cohorts

    Article • Journal of Public Health, September 2012, Oxford University Press (OUP)

    Prof Alex Bottle

  144. Association between patient and general practice characteristics and unplanned first-time admissions for cancer: observational study

    Article • British Journal of Cancer, July 2012, Nature

    Prof Alex Bottle

  145. Poor 1-Year Survival in Elderly Patients Undergoing Nonelective Colorectal Resection

    Article • Diseases of the Colon & Rectum, July 2012, Wolters Kluwer Health

    Prof Alex Bottle

  146. Independent Preoperative Predictors of Outcomes in Orthopedic and Vascular Surgery

    Article • Annals of Surgery, May 2012, Wolters Kluwer Health

    Prof Alex Bottle

  147. Creating a birth cohort to examine RSV bronchiolitis hospital admission rates among term and preterm infants in England

    Article • Archives of Disease in Childhood, May 2012, BMJ

    Prof Alex Bottle

  148. Rising acute throat infection admissions in children are not related to falling tonsillectomy rates

    Article • Archives of Disease in Childhood, May 2012, BMJ

    Prof Alex Bottle

  149. Examining the ‘gold standard’: a comparative critical analysis of three consecutive decades of monopolar transurethral resection of the prostate (TURP) outcomes

    Article • BJU International, April 2012, Wiley

    Prof Alex Bottle

  150. Using routine data to monitor inequalities in an acute trust: a retrospective study

    Article • BMC Health Services Research, April 2012, Springer Science + Business Media

    Prof Alex Bottle

  151. Assessment of administrative data for evaluating the shifting acquisition of Clostridium difficile infection in England

    Article • Journal of Hospital Infection, March 2012, Elsevier

    Prof Alex Bottle

  152. Reduced Risk of Medical Morbidity and Mortality in Patients Selected for Laparoscopic Colorectal Resection in England

    Article • Archives of Surgery, March 2012, American Medical Association (AMA)

    Prof Alex Bottle

  153. Impact of transfer for angioplasty and distance on AMI in-hospital mortality

    Article • Acute Cardiac Care, February 2012, Taylor & Francis

    Prof Alex Bottle

  154. Single measures of performance do not reflect overall institutional quality in colorectal cancer surgery

    Article • Gut, February 2012, BMJ

    Prof Alex Bottle

  155. Short-Term Outcomes Following Open Versus Minimally Invasive Esophagectomy for Cancer in England

    Article • Annals of Surgery, February 2012, Wolters Kluwer Health

    Prof Alex Bottle

  156. Mortality and morbidity following hip fractures related to hospital thromboprophylaxis policy

    Article • Hip International, January 2012, Wichtig

    Prof Alex Bottle

  157. Nationwide Study on Trends in Hospital Admissions for Major Cardiovascular Events and Procedures Among People With and Without Diabetes in England, 2004-2009

    Article • Diabetes Care, December 2011, American Diabetes Association

    Prof Alex Bottle

  158. Comorbidity scores for administrative data benefited from adaptation to local coding and diagnostic practices

    Article • Journal of Clinical Epidemiology, December 2011, Elsevier

    Prof Alex Bottle

  159. A Review of Patient Safety Measures Based on Routinely Collected Hospital Data

    Article • American Journal of Medical Quality, September 2011, SAGE Publications

    Prof Alex Bottle

  160. Logistic Versus Hierarchical Modeling: An Analysis of a Statewide Inpatient Sample

    Article • Journal of the American College of Surgeons, September 2011, Elsevier

    Prof Alex Bottle

  161. What is the role of risk-adjusted funnel plots in the analysis of radical cystectomy volume-outcome relationships?

    Article • BJU International, August 2011, Wiley

    Prof Alex Bottle

  162. Value of failure to rescue as a marker of the standard of care following reoperation for complications after colorectal resection

    Article • BJS, August 2011, Wiley

    Prof Alex Bottle

  163. Variation in reoperation after colorectal surgery in England as an indicator of surgical performance: retrospective analysis of Hospital Episode Statistics

    Article • BMJ, August 2011, BMJ

    Prof Alex Bottle

  164. Association of practice size and pay-for-performance incentives with the quality of diabetes management in primary care

    Article • Canadian Medical Association Journal, August 2011, Canadian Medical Association (CMA)

    Prof Alex Bottle

  165. Systematic review of discharge coding accuracy

    Article • Journal of Public Health, July 2011, Oxford University Press (OUP)

    Prof Alex Bottle

  166. Hospital Standardized Mortality Ratios: Sensitivity Analyses on the Impact of Coding

    Article • Health Services Research, July 2011, Wiley

    Prof Alex Bottle

  167. The comparison of cardiovascular risk scores using two methods of substituting missing risk factor data in patient medical records

    Article • Journal of Innovation in Health Informatics, July 2011, BCS Learning and Development Limited

    Prof Alex Bottle

  168. The performance of automated case-mix adjustment regression model building methods in a health outcome prediction setting

    Article • Health Care Management Science, May 2011, Springer Science + Business Media

    Prof Alex Bottle

  169. Uptake of the NHS Health Checks programme in a deprived, culturally diverse setting: cross-sectional study

    Article • Journal of Public Health, May 2011, Oxford University Press (OUP)

    Prof Alex Bottle

  170. Increased health burden associated with Clostridium difficile diarrhoea in patients with inflammatory bowel disease

    Article • Alimentary Pharmacology & Therapeutics, April 2011, Wiley

    Prof Alex Bottle

  171. Mo1566 Surgery for Benign Colorectal Polyps in England - Trends and Outcomes From 1997 to 2007

    Article • Gastrointestinal Endoscopy, April 2011, Elsevier

    Prof Alex Bottle

  172. Surgery for benign colorectal polyps in England - trends and outcomes from 1997 to 2007

    Article • Gut, March 2011, BMJ

    Prof Alex Bottle

  173. Polypectomy at colonoscopy and sigmoidoscopy in England: a review of national data between 1997 and 2007

    Article • Gut, March 2011, BMJ

    Prof Alex Bottle

  174. Inequalities in Stroke Patients' Management in English Public Hospitals: A Survey on 200,000 Patients

    Article • PLOS One, March 2011, PLOS

    Prof Alex Bottle

  175. The volume-outcome relationship for radical cystectomy in England: an analysis of outcomes other than mortality

    Article • BJU International, February 2011, Wiley

    Prof Alex Bottle

  176. Interventions to optimise prescribing in care homes: systematic review

    Article • Age and Ageing, January 2011, Oxford University Press (OUP)

    Prof Alex Bottle

  177. Association of population and primary healthcare factors with hospital admission rates for chronic obstructive pulmonary disease in England: national cross-sectional study

    Article • Thorax, November 2010, BMJ

    Prof Alex Bottle

  178. Volume analysis of outcome following restorative proctocolectomy

    Article • BJS, November 2010, Wiley

    Prof Alex Bottle

  179. Trial of Therapeutic Assessment in London: randomised controlled trial of Therapeutic Assessment versus standard psychosocial assessment in adolescents presenting with self-harm

    Article • Archives of Disease in Childhood, October 2010, BMJ

    Prof Alex Bottle

  180. A colorectal perspective on voluntary submission of outcome data to clinical registries

    Article • BJS, October 2010, Wiley

    Prof Alex Bottle

  181. Blood pressure monitoring and control by cardiovascular disease status in UK primary care: 10 year retrospective cohort study 1998-2007

    Article • Journal of Public Health, October 2010, Oxford University Press (OUP)

    Prof Alex Bottle

  182. Admission rates and in-hospital mortality for hip fractures in England 1998 to 2009: time trends study

    Article • Journal of Public Health, October 2010, Oxford University Press (OUP)

    Prof Alex Bottle

  183. Changes in the Incidence of Lower Extremity Amputations in Individuals With and Without Diabetes in England Between 2004 and 2008

    Article • Diabetes Care, September 2010, American Diabetes Association

    Prof Alex Bottle

  184. Impact of the seven-valent pneumococcal conjugate vaccination (PCV7) programme on childhood hospital admissions for bacterial pneumonia and empyema in England: national time-trends study, 1997-2008

    Article • Thorax, August 2010, BMJ

    Prof Alex Bottle

  185. Implementation of the NHS Health Checks programme: baseline assessment of risk factor recording in an urban culturally diverse setting

    Article • Family Practice, August 2010, Oxford University Press (OUP)

    Prof Alex Bottle

  186. Introduction of laparoscopic bariatric surgery in England: observational population cohort study

    Article • BMJ, August 2010, BMJ

    Prof Alex Bottle

  187. Predicting the false alarm rate in multi-institution mortality monitoring

    Article • Journal of the Operational Research Society, August 2010, Nature

    Prof Alex Bottle

  188. Open Versus Minimally Invasive Esophagectomy

    Article • Annals of Surgery, August 2010, Wolters Kluwer Health

    Prof Alex Bottle

  189. Ten-year trends in hospital admissions for adverse drug reactions in England 1999–2009

    Article • Journal of the Royal Society of Medicine, May 2010, SAGE Publications

    Prof Alex Bottle

  190. A plea for reason

    Article • BMJ, May 2010, BMJ

    Prof Alex Bottle

  191. Towards a scientific workflow methodology for primary care database studies

    Article • Statistical Methods in Medical Research, May 2010, SAGE Publications

    Prof Alex Bottle

  192. Elective colonic surgery for cancer in the elderly: an investigation into postoperative mortality in English NHS hospitals between 1996 and 2007

    Article • Colorectal Disease, April 2010, Wiley

    Prof Alex Bottle

  193. Hospital stay amongst patients undergoing major elective colorectal surgery: predicting prolonged stay and readmissions in NHS hospitals

    Article • Colorectal Disease, April 2010, Wiley

    Prof Alex Bottle

  194. 2084 HAS MODERN TURP EVOLVED OVER THREE DECADES?: A COMPARATIVE ANALYSIS

    Article • The Journal of Urology, April 2010, Elsevier

    Prof Alex Bottle

  195. Impact of Hospital Institutional Volume on Postoperative Mortality After Major Emergency Colorectal Surgery in English National Health Service Trusts, 2001 to 2005

    Article • Diseases of the Colon & Rectum, April 2010, Wolters Kluwer Health

    Prof Alex Bottle

  196. Nonelective Excisional Colorectal Surgery in English National Health Service Trusts: A Study of Outcomes from Hospital Episode Statistics Data between 1996 and 2007

    Article • Journal of the American College of Surgeons, April 2010, Elsevier

    Prof Alex Bottle

  197. The volume-mortality relation for radical cystectomy in England: retrospective analysis of hospital episode statistics

    Article • BMJ, March 2010, BMJ

    Prof Alex Bottle

  198. Increasing Skin Infections and Staphylococcus aureus Complications in Children, England, 1997–2006

    Article • Emerging Infectious Diseases, March 2010, Centers for Disease Control and Prevention (CDC)

    Prof Alex Bottle

  199. Trends in lower extremity amputations in people with and without diabetes in England, 1996–2005

    Article • Diabetes Research and Clinical Practice, February 2010, Elsevier

    Prof Alex Bottle

  200. The hospital standardised mortality ratio: a powerful tool for Dutch hospitals to assess their quality of care?

    Article • BMJ Quality & Safety, February 2010, BMJ

    Prof Alex Bottle

  201. Weekend mortality for emergency admissions. A large, multicentre study

    Article • BMJ Quality & Safety, January 2010, BMJ

    Prof Alex Bottle

  202. Strengths and weaknesses of hospital standardised mortality ratios

    Article • BMJ, January 2010, BMJ

    Prof Alex Bottle

  203. Impact of a Pay-for-Performance Incentive Scheme on Age, Sex, and Socioeconomic Disparities in Diabetes Management in UK Primary Care

    Article • Journal of Ambulatory Care Management, January 2010, Wolters Kluwer Health

    Prof Alex Bottle

  204. The impact of national guidelines for the prophylaxis of venous thromboembolism on the complications of arthroplasty of the lower limb

    Article • Journal of Bone and Joint Surgery - British Volume, January 2010, Bone & Joint

    Prof Alex Bottle

  205. Diverticular disease hospital admissions are increasing, with poor outcomes in the elderly and emergency admissions

    Article • Alimentary Pharmacology & Therapeutics, December 2009, Wiley

    Prof Alex Bottle

  206. Provision of radical pelvic urological surgery in England, and compliance with improving outcomes guidance

    Article • BJU International, November 2009, Wiley

    Prof Alex Bottle

  207. Increasing Short-Stay Unplanned Hospital Admissions among Children in England; Time Trends Analysis ’97–‘06

    Article • PLOS One, October 2009, PLOS

    Prof Alex Bottle

  208. Laparoscopically Assisted vs. Open Elective Colonic and Rectal Resection: A Comparison of Outcomes in English National Health Service Trusts Between 1996 and 2006

    Article • Diseases of the Colon & Rectum, October 2009, Wolters Kluwer Health

    Prof Alex Bottle

  209. Early In-Hospital Mortality following Trainee Doctors' First Day at Work

    Article • PLOS One, September 2009, PLOS

    Prof Alex Bottle

  210. Pay for perfomance and the quality of diabetes management in individuals with and without co-morbid medical conditions

    Article • Journal of the Royal Society of Medicine, September 2009, SAGE Publications

    Prof Alex Bottle

  211. Application of AHRQ patient safety indicators to English hospital data

    Article • BMJ Quality & Safety, August 2009, BMJ

    Prof Alex Bottle

  212. Is Laparoscopic Appendectomy Associated with Better Outcomes?

    Article • Annals of Surgery, May 2009, Wolters Kluwer Health

    Prof Alex Bottle

  213. Monitoring mortality

    Article • BMJ, April 2009, BMJ

    Prof Alex Bottle

  214. Funnel Plots and Their Emerging Application in Surgery

    Article • Annals of Surgery, March 2009, Wolters Kluwer Health

    Prof Alex Bottle

  215. Descriptive study of selected healthcare-associated infections using national Hospital Episode Statistics data 1996–2006 and comparison with mandatory reporting systems

    Article • Journal of Hospital Infection, December 2008, Elsevier

    Prof Alex Bottle

  216. Traditional and Laparoscopic Appendectomy in Adults

    Article • Annals of Surgery, November 2008, Wolters Kluwer Health

    Prof Alex Bottle

  217. Ethnic Disparities in Blood Pressure Management in Patients With Hypertension After the Introduction of Pay for Performance

    Article • The Annals of Family Medicine, November 2008, Annals of Family Medicine

    Prof Alex Bottle

  218. Trends in cardiovascular admissions and procedures for people with and without diabetes in England, 1996–2005

    Article • Diabetologia, October 2008, Springer Science + Business Media

    Prof Alex Bottle

  219. Laparoscopic and conventional appendicectomy in children: outcomes in English hospitals between 1996 and 2006

    Article • Pediatric Surgery International, September 2008, Springer Science + Business Media

    Prof Alex Bottle

  220. Volume–outcome relationship in surgical urology: Myth or reality?

    Article • British Journal of Medical and Surgical Urology, September 2008, SAGE Publications

    Prof Alex Bottle

  221. Trends in hospital admissions for pulmonary embolism in England: 1996/7 to 2005/6

    Article • Clinical Medicine, August 2008, Royal College of Physicians

    Prof Alex Bottle

  222. Quality of Primary Care and Hospital Admissions for Diabetes Mellitus in England

    Article • Journal of Ambulatory Care Management, July 2008, Wolters Kluwer Health

    Prof Alex Bottle

  223. Demonstrating safety through in-hospital mortality analysis following elective abdominal aortic aneurysm repair in England (Br J Surg 2008; 95: 64-71)

    Article • BJS, March 2008, Wiley

    Prof Alex Bottle

  224. Changing trends in surgery for acute appendicitis (Br J Surg 2008; 95: 363–368)

    Article • BJS, January 2008, Wiley

    Prof Alex Bottle

  225. Are hospital league tables calculated correctly? A commentary

    Article • Public Health, December 2007, Elsevier

    Prof Alex Bottle

  226. Hospital episode statistics v central cardiac audit database

    Article • BMJ, October 2007, BMJ

    Prof Alex Bottle

  227. Association Between Quality of Primary Care and Hospitalization for Coronary Heart Disease in England: National Cross-sectional Study

    Article • Journal of General Internal Medicine, October 2007, Springer Science + Business Media

    Prof Alex Bottle

  228. Intelligent Information: A National System for Monitoring Clinical Performance

    Article • Health Services Research, June 2007, Wiley

    Prof Alex Bottle

  229. Use of administrative data or clinical databases as predictors of risk of death in hospital: comparison of models

    Article • BMJ, May 2007, BMJ

    Prof Alex Bottle

  230. Identifying patients at high risk of emergency hospital admissions: a logistic regression analysis

    Article • Journal of the Royal Society of Medicine, August 2006, SAGE Publications

    Prof Alex Bottle

  231. Mortality associated with delay in operation after hip fracture: observational study

    Article • BMJ, March 2006, BMJ

    Prof Alex Bottle

  232. Obesity and type 2 diabetes in children, 1996-7 to 2003-4

    Article • BMJ, November 2005, BMJ

    Prof Alex Bottle

  233. Trends in day surgery rates

    Article • BMJ, October 2005, BMJ

    Prof Alex Bottle

  234. Variation in operation rates by primary care trust

    Article • BMJ, September 2005, BMJ

    Prof Alex Bottle

  235. Length of hospital stay and subsequent emergency readmission

    Article • BMJ, August 2005, BMJ

    Prof Alex Bottle

  236. “Frequent flier” patients

    Article • BMJ, April 2005, BMJ

    Prof Alex Bottle

  237. Variations in vaginal and abdominal hysterectomy by region and trust in England

    Article • BJOG An International Journal of Obstetrics & Gynaecology, March 2005, Wiley

    Prof Alex Bottle

  238. Monitoring changes in hospital standardised mortality ratios

    Article • BMJ, February 2005, BMJ

    Prof Alex Bottle

  239. Hospital admissions for drug and alcohol use in people aged under 45

    Article • BMJ, January 2005, BMJ

    Prof Alex Bottle

  240. Counting hospital activity: spells or episodes?

    Article • BMJ, November 2004, BMJ

    Prof Alex Bottle

  241. Paediatric cardiac surgical mortality in England after Bristol: descriptive analysis of hospital episode statistics 1991-2002

    Article • BMJ, October 2004, BMJ

    Prof Alex Bottle

  242. Prescribing of lipid regulating drugs and admissions for myocardial infarction in England

    Article • BMJ, September 2004, BMJ

    Prof Alex Bottle

  243. How often are adverse events reported in English hospital statistics?

    Article • BMJ, August 2004, BMJ

    Prof Alex Bottle

  244. Statistical issues in the prospective monitoring of health outcomes across multiple units

    Article • Journal of the Royal Statistical Society Series A (Statistics in Society), August 2004, Wiley

    Prof Alex Bottle

  245. Using GIS for Environmental Exposure Assessment

    Article • June 2004, Taylor & Francis

    Prof Alex Bottle

  246. Social class and elective caesareans in the English NHS

    Article • BMJ, June 2004, BMJ

    Prof Alex Bottle

  247. Some way to go for consistent implementation of guidance on hip fracture

    Article • BMJ, May 2004, BMJ

    Prof Alex Bottle

  248. Trends in admissions and deaths in English NHS hospitals

    Article • BMJ, April 2004, BMJ

    Prof Alex Bottle

  249. Discharge destination and length of stay: differences between US and English hospitals for people aged 65 and over

    Article • BMJ, March 2004, BMJ

    Prof Alex Bottle

  250. Acute stroke units and early CT scans are linked to lower in-hospital mortality rates

    Article • BMJ, February 2004, BMJ

    Prof Alex Bottle

  251. Controlling for provider of treatment in the modelling of respiratory disease risk near cokeworks

    Article • Statistics in Medicine, January 2004, Wiley

    Prof Alex Bottle

  252. Monitoring of mortality rates in primary care

    Article • The Lancet, October 2003, Elsevier

    Prof Alex Bottle

  253. Following Shipman: a pilot system for monitoring mortality rates in primary care

    Article • The Lancet, August 2003, Elsevier

    Prof Alex Bottle

  254. Hospital episode statistics: time for clinicians to get involved?

    Article • Clinical Medicine, September 2002, Royal College of Physicians

    Prof Alex Bottle

  255. Accessing and using hospital activity data

    Article • Journal of Public Health, March 2001, Oxford University Press (OUP)

    Prof Alex Bottle

  256. Proximity to coke works and hospital admissions for respiratory and cardiovascular disease in England and Wales

    Article • Thorax, March 2001, BMJ

    Prof Alex Bottle

  257. The productivity of British, American and Nigerian chemists compared

    Article • Journal of Information Science, June 1994, SAGE Publications

    Prof Alex Bottle