All Stories

  1. New Therapeutic Options Against Clinically Relevant Proteases in Cancer Progression

    Article • Mini-Reviews in Medicinal Chemistry, February 2026, Bentham Science Publishers

    Alessandro Parodi

  2. Unveiling the Roles of Cysteine Proteinases F and W: From Structure to Pathological Implications and Therapeutic Targets

    Article • Cells, May 2024, MDPI AG

    Alessandro Parodi

  3. Swelling, Rupture and Endosomal Escape of Biological Nanoparticles Per Se and Those Fused with Liposomes in Acidic Environment

    Article • Pharmaceutics, May 2024, MDPI AG

    Alessandro Parodi, Dr Ilya Gordeychuk

  4. Reprogramming Tumor-Associated Macrophage Using Nanocarriers: New Perspectives to Halt Cancer Progression

    Article • Pharmaceutics, May 2024, MDPI AG

    Alessandro Parodi

  5. Antiproliferative efficacy and mechanism of action of aggregation-resistant, polymorphous nanosilver functionalized with asparagus phytochemicals (Ar-AgNPs) in the breast adenocarcinoma MDA-MB-231 cells

    Article • Inorganica Chimica Acta, May 2024, Elsevier

    Alessandro Parodi

  6. Physiologically based pharmacokinetic model for predicting the biodistribution of albumin nanoparticles after induction and recovery from acute lung injury

    Article • Heliyon, May 2024, Elsevier

    Alessandro Parodi

  7. Bioprospecting of Chlamydomonas reinhardtii for boosting biofuel-related products production based on novel aggregation-induced emission active extracellular polymeric substances nanoprobes

    Article • Bioresource Technology, May 2024, Elsevier

    Alessandro Parodi

  8. The Intricate Balance between Life and Death: ROS, Cathepsins, and Their Interplay in Cell Death and Autophagy

    Article • International Journal of Molecular Sciences, April 2024, MDPI AG

    Alessandro Parodi

  9. The menace of severe adverse events and deaths associated with viral gene therapy and its potential solution

    Article • Medicinal Research Reviews, March 2024, Wiley

    Alessandro Parodi

  10. Clinical course and peculiarities of Parechovirus and Enterovirus central nervous system infections in newborns: a single-center experience

    Article • European Journal of Pediatrics, March 2024, Springer Science + Business Media

    Alessandro Parodi

  11. Disruption of Cerebellar Granular Layer as a Consequence of Germinal Matrix Intraventricular Hemorrhage in Extreme Prematurity: An Acute Direct Mechanism Too?

    Article • Pediatric Neurology, March 2024, Elsevier

    Alessandro Parodi

  12. Early Extra-Uterine Growth Restriction in Very-Low-Birth-Weight Neonates with Normal or Mildly Abnormal Brain MRI: Effects on a 2–3-Year Neurodevelopmental Outcome

    Article • Nutrients, February 2024, MDPI AG

    Alessandro Parodi

  13. Therapeutic and diagnostic applications of carbon nanotubes in cancer: recent advances and challenges

    Article • Journal of Drug Targeting, February 2024, Taylor & Francis

    Alessandro Parodi

  14. Bioactive peptides: an alternative therapeutic approach for cancer management

    Article • Frontiers in Immunology, January 2024, Frontiers

    Alessandro Parodi

  15. Early Extra-Uterine Growth Restriction in Very Low Birth Weight Neonates with Normal or Mildly Abnormal Brain MRI: Effects on 2–3 Years Neurodevelopmental Outcome

    Article • January 2024, MDPI AG

    Alessandro Parodi

  16. The Importance of Nanocarriers’ Intra- and Extracellular Degradation: What we Know and Should Know About it?

    Article • Current Medicinal Chemistry, January 2024, Bentham Science Publishers

    Alessandro Parodi

  17. Single-Step Fabrication of Resonant Silicon–Gold Hybrid Nanoparticles for Efficient Optical Heating and Nanothermometry in Cells

    Article • ACS Applied Nano Materials, October 2023, American Chemical Society (ACS)

    Alessandro Parodi

  18. Expression, Intracellular Localization, and Maturation of Cysteine Cathepsins in Renal Embryonic and Cancer Cell Lines

    Article • Biochemistry (Moscow), July 2023, Pleiades Publishing Ltd

    Alessandro Parodi

  19. Smart Delivery Systems Responsive to Cathepsin B Activity for Cancer Treatment

    Article • Pharmaceutics, June 2023, MDPI AG

    Alessandro Parodi

  20. Proteolytic Resistance Determines Albumin Nanoparticle Drug Delivery Properties and Increases Cathepsin B, D, and G Expression

    Article • International Journal of Molecular Sciences, June 2023, MDPI AG

    Alessandro Parodi

  21. Technological aspects of manufacturing and analytical control of biological nanoparticles

    Article • Biotechnology Advances, May 2023, Elsevier

    Alessandro Parodi

  22. Hydroxychloroquine Enhances Cytotoxic Properties of Extracellular Vesicles and Extracellular Vesicle–Mimetic Nanovesicles Loaded with Chemotherapeutics

    Article • Pharmaceutics, February 2023, MDPI AG

    Alessandro Parodi, Dr Ilya Gordeychuk

  23. Surface topography of nanoplastics modulates their internalization and toxicity in liver cells

    Article • Environmental Science Nano, January 2023, Royal Society of Chemistry

    Alessandro Parodi

  24. Hydroxychloroquine Enhances Cytotoxic Properties of Extracellular Vesicles and Extracellular Vesicle-Mimetic Nanovesicles Loaded with Chemotherapeutics

    Article • December 2022, MDPI AG

    Alessandro Parodi, Dr Ilya Gordeychuk

  25. Cathepsin K in Pathological Conditions and New Therapeutic and Diagnostic Perspectives

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Alessandro Parodi

  26. Anticancer Nanotherapeutics in Clinical Trials: The Work behind Clinical Translation of Nanomedicine

    Article • International Journal of Molecular Sciences, November 2022, MDPI AG

    Alessandro Parodi

  27. Biomimetic approaches for targeting tumor-promoting inflammation

    Article • Seminars in Cancer Biology, November 2022, Elsevier

    Alessandro Parodi

  28. Physiologically Based Pharmacokinetic Modeling of Nanoparticle Biodistribution: A Review of Existing Models, Simulation Software, and Data Analysis Tools

    Article • International Journal of Molecular Sciences, October 2022, MDPI AG

    Alessandro Parodi

  29. New Advances in the Understanding of Proteases as Diagnostic and Pharmaceutical Targets in Homeostatic and Pathologic Conditions

    Article • Pharmaceutics, July 2022, MDPI AG

    Alessandro Parodi

  30. In Silico, In Vitro, and Clinical Investigations of Cathepsin B and Stefin A mRNA Expression and a Correlation Analysis in Kidney Cancer

    Article • Cells, April 2022, MDPI AG

    Alessandro Parodi

  31. Nanomedicine for Treating Diabetic Retinopathy Vascular Degeneration

    Article • International Journal of Translational Medicine, November 2021, MDPI AG

    Alessandro Parodi

  32. Nanomedicine for increasing the oral bioavailability of cancer treatments

    Article • Journal of Nanobiotechnology, October 2021, Springer Science + Business Media

    Alessandro Parodi

  33. Cathepsin D—Managing the Delicate Balance

    Article • Pharmaceutics, June 2021, MDPI AG

    Alessandro Parodi

  34. Long Non-Coding PROX1-AS1 Expression Correlates with Renal Cell Carcinoma Metastasis and Aggressiveness

    Article • Non-Coding RNA, April 2021, MDPI AG

    Alessandro Parodi

  35. Endosomal Escape of Polymer‐Coated Silica Nanoparticles in Endothelial Cells

    Article • Small, July 2020, Wiley

    Alessandro Parodi, Michael Evangelopoulos

  36. Liposome-Embedding Silicon Microparticle for Oxaliplatin Delivery in Tumor Chemotherapy

    Article • Pharmaceutics, June 2020, MDPI AG

    Alessandro Parodi, Dr Marcello Locatelli

  37. Smart Nanotheranostics Responsive to Pathological Stimuli

    Article • Frontiers in Bioengineering and Biotechnology, May 2020, Frontiers

    Alessandro Parodi

  38. Cysteine Cathepsins Inhibition Affects Their Expression and Human Renal Cancer Cell Phenotype

    Article • Cancers, May 2020, MDPI AG

    Alessandro Parodi

  39. Cellular Aging Characteristics and Their Association with Age-Related Disorders

    Article • Antioxidants, January 2020, MDPI AG

    Alessandro Parodi

  40. Biomimetic cellular vectors for enhancing drug delivery to the lungs

    Article • Scientific Reports, January 2020, Springer Science + Business Media

    Alessandro Parodi, Michael Evangelopoulos

  41. The Role of Cysteine Cathepsins in Cancer Progression and Drug Resistance

    Article • International Journal of Molecular Sciences, July 2019, MDPI AG

    Alessandro Parodi

  42. Albumin Nanovectors in Cancer Therapy and Imaging

    Article • Biomolecules, June 2019, MDPI AG

    Alessandro Parodi

  43. Established and Emerging Strategies for Drug Delivery Across the Blood-Brain Barrier in Brain Cancer

    Article • Pharmaceutics, May 2019, MDPI AG

    Alessandro Parodi

  44. Inflammation and Cancer: In Medio Stat Nano

    Article • Current Medicinal Chemistry, December 2018, Bentham Science Publishers

    Dr Ennio Tasciotti, Michael Evangelopoulos, Alessandro Parodi

  45. Trends towards Biomimicry in Theranostics

    Article • Nanomaterials, August 2018, MDPI AG

    Michael Evangelopoulos, Alessandro Parodi

  46. Bio-inspired engineering of cell- and virus-like nanoparticles for drug delivery

    Article • Biomaterials, December 2017, Elsevier

    Alessandro Parodi, Michael Evangelopoulos

  47. Ghee Butter as a Therapeutic Delivery System

    Article • Journal of Nanoscience and Nanotechnology, February 2017, American Scientific Publishers

    Alessandro Parodi, Michael Evangelopoulos

  48. Biomimetic carriers mimicking leukocyte plasma membrane to increase tumor vasculature permeability

    Article • Scientific Reports, October 2016, Springer Science + Business Media

    Michael Evangelopoulos, Alessandro Parodi

  49. Abstract 3910: Biomimetic proteo-lipid vesicles for the treatment of melanoma

    Article • Cancer Research, July 2016, American Association for Cancer Research (AACR)

    Alessandro Parodi

  50. Effects of the protein corona on liposome–liposome and liposome–cell interactions

    Article • International Journal of Nanomedicine, July 2016, Dove Medical Press

    Dr Ennio Tasciotti, Alessandro Parodi

  51. Biomimetic proteolipid vesicles for targeting inflamed tissues

    Article • Nature Materials, May 2016, Springer Science + Business Media

    Michael Evangelopoulos, Alessandro Parodi

  52. One-pot synthesis of pH-responsive hybrid nanogel particles for the intracellular delivery of small interfering RNA

    Article • Biomaterials, May 2016, Elsevier

    Dr Ennio Tasciotti, Michael Evangelopoulos, Alessandro Parodi

  53. Biologically Inspired Nanomaterials and Nanobiomagnetism: A Synergy among New Emerging Concepts in Regenerative Medicine

    Article • March 2016, Taylor & Francis

    Alessandro Parodi

  54. Cell source determines the immunological impact of biomimetic nanoparticles

    Article • Biomaterials, March 2016, Elsevier

    Dr Iman K Yazdi, Dr Ennio Tasciotti, Michael Evangelopoulos, Alessandro Parodi

  55. Case Study: Application of LeukoLike Technology to Camouflage Nanoparticles from the Immune Recognition

    Article • February 2016, World Scientific Pub Co Pte Lt

    Dr Ennio Tasciotti, Alessandro Parodi

  56. The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery

    Article • Nanomedicine, January 2016, Future Medicine

    Dr Alessandro Parodi, Dr Ennio Tasciotti, Alessandro Parodi

  57. Biomimetic interfaces to trigger tissue restoration

    Article • Frontiers in Bioengineering and Biotechnology, January 2016, Frontiers

    Alessandro Parodi

  58. Proteomic Profiling of a Biomimetic Drug Delivery Platform

    Article • Current Drug Targets, October 2015, Bentham Science Publishers

    Dr Ennio Tasciotti, Alessandro Parodi

  59. Abstract 4536: Biomimetic carriers modulate tumor vascular barrier function

    Article • Cancer Research, August 2015, American Association for Cancer Research (AACR)

    Dr Ennio Tasciotti, Alessandro Parodi

  60. Enabling cytoplasmic delivery and organelle targeting by surface modification of nanocarriers

    Article • Nanomedicine, July 2015, Future Medicine

    Dr Ennio Tasciotti, Alessandro Parodi

  61. Bromelain Surface Modification Increases the Diffusion of Silica Nanoparticles in the Tumor Extracellular Matrix

    Article • ACS Nano, October 2014, American Chemical Society (ACS)

    Dr Iman K Yazdi, Alessandro Parodi

  62. Abstract 4586: The Leukosome: A biomimetic liposome for the targeting of inflamed tumor vasculature

    Article • Cancer Research, September 2014, American Association for Cancer Research (AACR)

    Dr Ennio Tasciotti, Michael Evangelopoulos, Alessandro Parodi

  63. Electrophysiology and biochemical analysis of cyclocreatine uptake and effect in hippocampal slices

    Article • Journal of Integrative Neuroscience, June 2013, World Scientific Pub Co Pte Lt

    Alessandro Parodi

  64. Synthetic nanoparticles functionalized with biomimetic leukocyte membranes possess cell-like functions

    Article • Nature Physics, December 2012, Springer Science + Business Media

    Dr Ciro Chiappini, Dr Iman K Yazdi, Dr Ennio Tasciotti, Michael Evangelopoulos, Alessandro Parodi

  65. Evaluation of Cell Function Upon Nanovector Internalization

    Article • Small, November 2012, Wiley

    Dr Ennio Tasciotti, Alessandro Parodi

  66. Encyclopedia of Nanotechnology

    Article • January 2012, Springer Science + Business Media

    Alessandro Parodi

  67. Interactions of single-wall carbon nanotubes with endothelial cells

    Article • Nanomedicine Nanotechnology Biology and Medicine, April 2010, Elsevier

    Alessandro Parodi

  68. A comparative study of leukaemia inhibitory factor and interleukin-1α intracellular content in a human keratinocyte cell line after exposure to cosmetic fragrances and sodium dodecyl sulphate

    Article • Toxicology Letters, February 2010, Elsevier

    Alessandro Parodi

  69. Cytotoxic effect on human keratinocytes of crude extracts from planktonic Cnidaria

    Article • Journal of Biological Research - Bollettino della Società Italiana di Biologia Sperimentale, January 2009, PAGEPress Publications

    Alessandro Parodi

  70. Salvia somalensis essential oil as a potential cosmetic ingredient: solvent‐free microwave extraction, hydrodistillation, GC–MS analysis, odour evaluation and in vitro cytotoxicity assays

    Article • International Journal of Cosmetic Science, January 2009, Wiley

    Alessandro Parodi

  71. Comparison of the irritation potentials of Boswellia serrata gum resin and of acetyl-11-keto-β-boswellic acid by in vitro cytotoxicity tests on human skin-derived cell lines

    Article • Toxicology Letters, March 2008, Elsevier

    Alessandro Parodi

  72. 3,3,5‐Trimethylcyclohexanols and derived esters: green synthetic procedures, odour evaluation and in vitro skin cytotoxicity assays1

    Article • International Journal of Cosmetic Science, November 2006, Wiley

    Alessandro Parodi

  73. The creatine transporter mediates the uptake of creatine by brain tissue, but not the uptake of two creatine-derived compounds

    Article • Neuroscience, November 2006, Elsevier

    Professor Tullio Florio, Alessandro Parodi

  74. Handbook of Immunological Properties of Engineered Nanomaterials

    Article • World Scientific Pub Co Pte Lt

    Alessandro Parodi, Neill Liptrott