All Stories

  1. The subjective effects of gabapentin are like depressants with abuse potential.

    Article • Experimental and Clinical Psychopharmacology, January 2024, American Psychological Association (APA)

    Professor and Department Head Adam Prus

  2. Lack of sex and estrous stage effects on compulsive behavior assessed using a schedule-induced polydipsia procedure in rats

    Article • Behavioural Pharmacology, March 2023, Wolters Kluwer Health

    Professor and Department Head Adam Prus

  3. Assessment of antidepressant-like effects of dextromethorphan on differential reinforcement of low-rate 72-s performance in rats

    Article • Behavioural Pharmacology, August 2021, Wolters Kluwer Health

    Professor and Department Head Adam Prus

  4. Conditioned Place Preference Test for Assessing the Rewarding Effects of Drugs of Abuse

    Article • December 2020, Springer Science + Business Media

    Professor and Department Head Adam Prus

  5. Drug Discrimination: Historical Origins, Important Concepts, and Principles

    Article • January 2018, Springer Science + Business Media

    Professor and Department Head Adam Prus

  6. The Neurotensin NTS1 Receptor Agonist PD149163 Produces Antidepressant‐Like Effects in the Forced Swim Test: Further Support for Neurotensin as a Novel Pharmacologic Strategy for Antidepressant Drugs

    Article • Drug Development Research, July 2017, Wiley

    Professor and Department Head Adam Prus

  7. Neurotensin NTS 1 and NTS 2 receptor agonists produce anxiolytic-like effects in the 22-kHz ultrasonic vocalization model in rats

    Article • Brain Research, March 2017, Elsevier

    Professor and Department Head Adam Prus

  8. Translational Value of Drug Discrimination with Typical and Atypical Antipsychotic Drugs

    Article • January 2017, Springer Science + Business Media

    Professor and Department Head Adam Prus

  9. Discriminative stimulus properties of 1.25 mg/kg clozapine in rats: Mediation by serotonin 5-HT 2 and dopamine D 4 receptors

    Article • Brain Research, October 2016, Elsevier

    Professor and Department Head Adam Prus

  10. The Discriminative Stimulus Properties of Drugs Used to Treat Depression and Anxiety

    Article • January 2016, Springer Science + Business Media

    Professor and Department Head Adam Prus

  11. The antidepressant drugs fluoxetine and duloxetine produce anxiolytic-like effects in a schedule-induced polydipsia paradigm in rats

    Article • Behavioural Pharmacology, August 2015, Wolters Kluwer Health

    Professor and Department Head Adam Prus

  12. The quetiapine active metabolite N-desalkylquetiapine and the neurotensin NTS₁ receptor agonist PD149163 exhibit antidepressant-like effects on operant responding in male rats.

    Article • Experimental and Clinical Psychopharmacology, December 2014, American Psychological Association (APA)

    Professor and Department Head Adam Prus

  13. The Discriminative Stimulus Effects of the Neurotensin NTS1Receptor Agonist PD149163 in Rats: Stimulus Generalization Testing with Dopamine D1and D2Receptor Ligands

    Article • Drug Development Research, March 2014, Wiley

    Professor and Department Head Adam Prus

  14. Acute, but not repeated, administration of the neurotensin NTS1 receptor agonist PD149163 decreases conditioned footshock-induced ultrasonic vocalizations in rats

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, March 2014, Elsevier

    Professor and Department Head Adam Prus

  15. Systemic administration of the neurotensin NTS₁-receptor agonist PD149163 improves performance on a memory task in naturally deficient male Brown Norway rats.

    Article • Experimental and Clinical Psychopharmacology, January 2014, American Psychological Association (APA)

    Professor and Department Head Adam Prus

  16. Effects of the neurotensin NTS1 receptor agonist PD149163 on visual signal detection in rats

    Article • European Journal of Pharmacology, December 2013, Elsevier

    Professor and Department Head Adam Prus

  17. Assessment of attention in male and female Brattleboro rats using a self-paced five-choice serial reaction time task

    Article • Brain Research, November 2013, Elsevier

    Professor and Department Head Adam Prus

  18. The neurotensin-1 receptor agonist PD149163 inhibits conditioned avoidance responding without producing catalepsy in rats

    Article • European Neuropsychopharmacology, July 2011, Elsevier

    Professor and Department Head Adam Prus

  19. Evaluation of the effects of α2 adrenoceptor antagonism with the D2 receptor antagonist raclopride on conditioned avoidance responding in rats

    Article • Behavioural Pharmacology, October 2010, Wolters Kluwer Health

    Professor and Department Head Adam Prus

  20. Discriminative stimulus properties of idazoxan: mediation by both α2 adrenoceptor antagonism and 5‐HT1A receptor agonism

    Article • Drug Development Research, June 2010, Wiley

    Professor and Department Head Adam Prus

  21. Differential Effects of M1 and 5-Hydroxytryptamine1A Receptors on Atypical Antipsychotic Drug-Induced Dopamine Efflux in the Medial Prefrontal Cortex

    Article • Journal of Pharmacology and Experimental Therapeutics, June 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Professor and Department Head Adam Prus

  22. Drug discrimination: 30 years of progress

    Article • Psychopharmacology, February 2009, Springer Science + Business Media

    Professor and Department Head Adam Prus

  23. Further characterization of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in C57BL/6 mice: role of 5-HT2A serotonergic and α1 adrenergic antagonism

    Article • Psychopharmacology, November 2008, Springer Science + Business Media

    Professor and Department Head Adam Prus

  24. Acute nicotine reduces and repeated nicotine increases spontaneous activity in male and female Lewis rats

    Article • Pharmacology Biochemistry and Behavior, November 2008, Elsevier

    Dr Alan Lars Pehrson, Professor and Department Head Adam Prus

  25. Discriminative stimulus properties of atypical and typical antipsychotic drugs: a review of preclinical studies

    Article • Psychopharmacology, September 2008, Springer Science + Business Media

    Professor and Department Head Adam Prus

  26. The role of M1 muscarinic cholinergic receptors in the discriminative stimulus properties of N-desmethylclozapine and the atypical antipsychotic drug clozapine in rats

    Article • Psychopharmacology, August 2008, Springer Science + Business Media

    Dr Alan Lars Pehrson, Professor and Department Head Adam Prus

  27. Acute behavioral tolerance to nicotine in the conditioned taste aversion paradigm

    Article • Drug Development Research, December 2007, Wiley

    Professor and Department Head Adam Prus

  28. The neurotensin analog NT69L enhances medial prefrontal cortical dopamine and acetylcholine efflux: Potentiation of risperidone-, but not haloperidol-, induced dopamine efflux

    Article • Brain Research, December 2007, Elsevier

    Professor and Department Head Adam Prus

  29. AC260584 (4-[3-(4-butylpiperidin-1-yl)-propyl]-7-fluoro-4H-benzo[1,4]oxazin-3-one), a selective muscarinic M1 receptor agonist, increases acetylcholine and dopamine release in rat medial prefrontal cortex and hippocampus

    Article • European Journal of Pharmacology, October 2007, Elsevier

    Professor and Department Head Adam Prus

  30. 5-HT6 receptor antagonist SB-399885 potentiates haloperidol and risperidone-induced dopamine efflux in the medial prefrontal cortex or hippocampus

    Article • Brain Research, February 2007, Elsevier

    Professor and Department Head Adam Prus

  31. NK3 receptor antagonists for the treatment of schizophrenia

    Article • Drug Discovery Today Therapeutic Strategies, December 2006, Elsevier

    Professor and Department Head Adam Prus

  32. Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25???mg/kg clozapine vs. 5.0???mg/kg clozapine vs. vehicle

    Article • Behavioural Pharmacology, March 2006, Wolters Kluwer Health

    Dr Alan Lars Pehrson, Professor and Department Head Adam Prus

  33. Serotonergic mechanisms in schizophrenia: Evolution and current concepts

    Article • Current Psychosis & Therapeutics Reports, March 2006, Springer Science + Business Media

    Professor and Department Head Adam Prus

  34. Generalization to atypical antipsychotic drugs depends on training dose in rats trained to discriminate 1.25 mg/kg clozapine versus 5.0 mg/kg clozapine versus vehicle in a three-choice drug discrimination task

    Article • Behavioural Pharmacology, November 2005, Wolters Kluwer Health

    Professor and Department Head Adam Prus

  35. ACP-103, a 5-HT2A/2C inverse agonist, potentiates haloperidol-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens

    Article • Psychopharmacology, October 2005, Springer Science + Business Media

    Professor and Department Head Adam Prus

  36. Serotonin receptor mechanisms mediate the discriminative stimulus properties of the atypical antipsychotic clozapine in C57BL/6 mice

    Article • Psychopharmacology, February 2005, Springer Science + Business Media

    Dr Alan Lars Pehrson, Professor and Department Head Adam Prus

  37. Generalization testing with atypical and typical antipsychotic drugs in rats trained to discriminate 5.0 mg/kg clozapine from vehicle in a two-choice drug discrimination task

    Article • Drug Development Research, January 2005, Wiley

    Dr Alan Lars Pehrson, Professor and Department Head Adam Prus

  38. Discriminative stimulus properties of the atypical antipsychotic clozapine and the typical antipsychotic chlorpromazine in a three-choice drug discrimination procedure in rats

    Article • Psychopharmacology, August 2004, Springer Science + Business Media

    Professor and Department Head Adam Prus

  39. Discriminative stimulus properties of 1.25 and 5.0 mg/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms

    Article • Pharmacology Biochemistry and Behavior, February 2004, Elsevier

    Professor and Department Head Adam Prus

  40. Reevaluation of PNU-99194A discriminative stimulus effects

    Article • Pharmacology Biochemistry and Behavior, November 2002, Elsevier

    Professor and Department Head Adam Prus

  41. Common discriminative stimulus properties in rats of muscarinic antagonists, clozapine and the D 3 preferring antagonist PNU-99194A: an analysis of possible mechanisms

    Article • Behavioural Pharmacology, September 2001, Wolters Kluwer Health

    Professor and Department Head Adam Prus