All Stories

  1. Habitual exercisers versus sedentary subjects with Parkinson's Disease: Multimodal PET and fMRI study
  2. Win-Concurrent Sensory Cues Can Promote Riskier Choice
  3. Operationalizing Neuroimaging for Disorders of Consciousness in the Canadian Context
  4. Developing consensus among movement disorder specialists on clinical indicators for identification and management of advanced Parkinson’s disease: a multi-country Delphi-panel approach
  5. Neurobiology of placebo effect in Parkinson's disease: What we have learned and where we are going
  6. PBB3 binding in a patient with corticobasal syndrome
  7. Conclusions
  8. Dyskinesias and levodopa therapy: why wait?
  9. Challenges and unfulfilled promises in Parkinson's disease
  10. DNAJC12 and dopa-responsive nonprogressive parkinsonism
  11. Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy
  12. Homozygous alpha-synuclein p.A53V in familial Parkinson's disease
  13. PBB3 imaging in Parkinsonian disorders: Evidence for binding to tau and other proteins
  14. Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies
  15. Gender differences in Parkinson's disease depression
  16. Glucose utilization: still in the synapse
  17. The underlying mechanism of prodromal PD: insights from the parasympathetic nervous system and the olfactory system
  18. Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers
  19. Editors' Note: The 200th Anniversary of the Shaking Palsy
  20. Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient
  21. Tau imaging in progressive supranuclear palsy
  22. Renovo
  23. Ethical and Clinical Considerations at the Intersection of Functional Neuroimaging and Disorders of Consciousness
  24. Reply to letter to the editor: Is there anything more to learn from SWEDD?
  25. DCTN1 p.K56R in progressive supranuclear palsy
  26. Raul de la Fuente-Fernandez, February 22, 1959-May 11, 2016
  27. Salivary gland biopsy for diagnosis of Parkinson's disease?
  28. The role of biomarkers and imaging in Parkinson’s disease
  29. Movement disorders
  30. Optimizing diagnosis in Parkinson's disease: Radionuclide imaging
  31. Comment: Increased D3binding—A substrate for levodopa-induced dyskinesias?
  32. A scan without evidence is not evidence of absence: Scans without evidence of dopaminergic deficit in a symptomatic leucine-rich repeat kinase 2 mutation carrier
  33. Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease
  34. Canadian Perspectives on the Clinical Actionability of Neuroimaging in Disorders of Consciousness
  35. The Saskatchewan Movement Disorders Program: Commitment Pays Off
  36. Imaging in Parkinson’s disease: time to look below the neck
  37. Phosphorylated α-synuclein in Parkinson’s disease: correlation depends on disease severity
  38. Clinical Correlations With Lewy Body Pathology in LRRK2 -Related Parkinson Disease
  39. DNAJC13genetic variants in parkinsonism
  40. A familial form of parkinsonism, dementia, and motor neuron disease: A longitudinal study
  41. Central pharmacokinetics of levodopa: Lessons from imaging studies
  42. Clinical, positron emission tomography, and pathological studies of DNAJC13 p.N855S Parkinsonism
  43. DAT-SPECT diagnoses dopamine depletion, but not PD
  44. Imaging insights into basal ganglia function, Parkinson's disease, and dystonia
  45. In vivo dopaminergic and serotonergic dysfunction inDCTN1gene mutation carriers
  46. Gene therapy for Parkinson's disease: a step closer?
  47. Developments in neuroimaging: positron emission tomography
  48. Imaging of Dopamine and Serotonin Receptors and Transporters
  49. Insights into LRRK2-Mutation Related PD from PET Imaging Studies
  50. Parkinson’s Disease
  51. The effects of exercise on cognition in Parkinson’s disease: a systematic review
  52. Measurements of Dopaminergic Function in the Rat Brain Using [18F]FDOPA PET and Microdialysis
  53. Mechanisms and therapeutic implications of the placebo effect in neurological and psychiatric conditions
  54. DNAJC13 mutations in Parkinson disease
  55. Decisions under risk in Parkinson’s disease: Preserved evaluation of probability and magnitude
  56. SLC20A2 and THAP1 deletion in familial basal ganglia calcification with dystonia
  57. The Nature of Progression in Parkinson’s Disease: An Application of Non-Linear, Multivariate, Longitudinal Random Effects Modelling
  58. Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations
  59. Anterior brain glucose hypometabolism predates dementia in progranulin mutation carriers
  60. Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
  61. Novel spatial analysis method for PET images using 3D moment invariants: Applications to Parkinson's disease
  62. Neurology in Canada: History of the Canadian Neurological Society
  63. Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis
  64. Neuroimaging of Sleep and Sleep Disorders
  65. Imaging striatal dopaminergic function inPhospholipase A2 Group VI-related parkinsonism
  66. In-vivo Measurement of LDOPA Uptake, Dopamine Reserve and Turnover in the Rat Brain Using [18F]FDOPA PET
  67. Creation of an Open-Access, Mutation-Defined Fibroblast Resource for Neurological Disease Research
  68. Biomarkers for trials of neuroprotection in Parkinson's disease
  69. Imaging neural correlates of mild cognitive impairment in Parkinson's disease
  70. Neuroimaging: Current role in detecting pre-motor Parkinson's disease
  71. DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function
  72. Variant ataxia-telangiectasia presenting as primary-appearing dystonia in Canadian Mennonites
  73. Neuroimaging
  74. Neuroimaging in the early diagnosis of neurodegenerative disease
  75. Cerebrospinal fluid amyloid   and tau in LRRK2 mutation carriers
  76. Advances in imaging in Parkinson's disease
  77. Longitudinal evolution of compensatory changes in striatal dopamine processing in Parkinson's disease
  78. Liquid Xenon Detectors for Positron Emission Tomography
  79. Dopaminergic Imaging in Parkinson’s Disease: PET
  80. Functional Imaging Studies in Parkinson's Disease: The Non-Dopaminergic Systems
  81. A family with parkinsonism, essential tremor, restless legs syndrome, and depression
  82. Milestones in neuroimaging
  83. Ethical Issues In The Management Of Parkinson’S Disease
  84. Age-specific progression of nigrostriatal dysfunction in Parkinson's disease
  85. Neuroimaging in Parkinson’s Disease
  86. Movement disorders: new insights into Parkinson's disease
  87. Dopamine turnover increases in asymptomatic LRRK2 mutations carriers
  88. Parkin and Parkinson's disease: Differentiated by non-dopaminergic dysfunction?
  89. Effects of Expectation on Placebo-Induced Dopamine Release in Parkinson Disease
  90. Continuous dopaminergic therapy in Parkinson disease: Time to stride back?
  91. Response to Heat Pain Stimulation in Idiopathic Parkinson's Disease
  92. Effect of electroconvulsive therapy on brain 5-HT2 receptors in major depression
  93. Scans without evidence of dopamine deficiency: The triumph of careful clinical assessment
  94. Dopamine transporter PET in normal aging: Dopamine transporter decline and its possible role in preservation of motor function
  95. Imaging the nigrostriatal system to monitor disease progression and treatment-induced complications
  96. Functional imaging studies of non-motoric manifestations of Parkinson's Disease
  97. Longitudinal progression of sporadic Parkinson's disease: a multi-tracer positron emission tomography study
  98. Genetic factors influencing age at onset in LRRK2-linked Parkinson disease
  99. Visualizing vesicular dopamine dynamics in Parkinson's disease
  100. Familial parkinsonism: Study of original Sagamihara PARK8 (I2020T) kindred with variable clinicopathologic outcomes
  101. Pallidonigral TDP-43 pathology in Perry syndrome
  102. Dopamine transporter relation to levodopa-derived synaptic dopamine in a rat model of Parkinson’s: anin vivoimaging study
  103. DCTN1 mutations in Perry syndrome
  104. Radionuclide scanning to diagnose Parkinson disease: is it cost-effective?
  105. Progression of dopaminergic dysfunction in a LRRK2 kindred: A multitracer PET study
  106. PET demonstrates reduced dopamine transporter expression in PD with dyskinesias
  107. Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: A double blind video-based analysis
  108. Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
  109. Invited Article: Functional imaging in Parkinson disease
  110. Potential therapeutic targets for Parkinson's disease
  111. Dihydrotetrabenazine positron emission tomography imaging in early, untreated Parkinson's disease
  112. Neuroimaging
  113. Ten-year follow-up of Parkinson's disease patients randomized to initial therapy with ropinirole or levodopa
  114. Gene therapy for Parkinson's disease: early data
  115. Understanding the Placebo Effect: Contributions from Neuroimaging
  116. Dopamine transporter relation to dopamine turnover in Parkinson's disease: a positron emission tomography study
  117. Is there seasonal variation in risk of Parkinson's disease?
  118. Positron emission tomography in premotor Parkinson's disease
  119. Randomized trial of the triple monoamine reuptake inhibitor NS 2330 (tesofensine) in early Parkinson's disease
  120. Correction
  121. Autosomal dominant dystonia-plus with cerebral calcifications
  122. Genetic heterogeneity in paroxysmal nonkinesigenic dyskinesia
  123. Oral methylphenidate fails to elicit significant changes in extracellular putaminal dopamine levels in Parkinson's disease patients: Positron emission tomographic studies
  124. GDNF in treatment of Parkinson's disease: response to editorial
  125. Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease
  126. Age-related differences in levodopa dynamics in Parkinson's: implications for motor complications
  127. Expectation and the placebo effect in Parkinson's disease patients with subthalamic nucleus deep brain stimulation
  128. PET in LRRK2 mutations: comparison to sporadic Parkinson's disease and evidence for presymptomatic compensation
  129. Positron emission tomography after fetal transplantation in Huntington's disease
  130. Treatment for the progression of Parkinson's disease
  131. Parkinson's disease: in vivo assessment of disease progression using positron emission tomography
  132. The placebo response as a reward mechanism
  133. Hot spots: Can positron emission tomography offer insights into the pathogenesis of PD?
  134. Positron Emission Tomography in Parkinson’s Disease
  135. The Placebo Effect in Parkinson’s Disease
  136. Lack of Regional Selectivity During the Progression of Parkinson Disease
  137. Levodopa-induced changes in synaptic dopamine levels increase with progression of Parkinson's disease: implications for dyskinesias
  138. Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology
  139. Tremor induced by thalamic deep brain stimulation in patients with complex regional facial pain
  140. Clustering of Parkinson Disease
  141. Placebo mechanisms and reward circuitry: clues from Parkinson's disease
  142. Willing oneself better on placebo—effective in its own right
  143. Profile of families with parkinsonism-predominant spinocerebellar ataxia type 2 (SCA2)
  144. Presynaptic mechanisms of motor fluctuations in Parkinson’s disease: a probabilistic model
  145. Impact of the Spatial Normalization Template and Realignment Procedure on the SPM Analysis of [11C]Raclopride PET Studies
  146. The PARK8 Locus in Autosomal Dominant Parkinsonism: Confirmation of Linkage and Further Delineation of the Disease-Containing Interval
  147. Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease
  148. [11C]DTBZ-PET correlates of levodopa responses in asymmetric Parkinson's disease
  149. Agonizing over dopaminergic replacement therapy—lessons from animal models of parkinson’s disease
  150. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
  151. Neural transplantation for the treatment of Parkinson's disease
  152. Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study
  153. Central administration of the neurotensin receptor antagonist sr48692 attenuates vacuous chewing movements in a rodent model of tardive dyskinesia
  154. VMAT2 binding is elevated in dopa-responsive dystonia: Visualizing empty vesicles by PET
  155. Leg muscle strength is reduced in Parkinson's disease and relates to the ability to rise from a chair
  156. Effects of oligonucleotide antisense to dopamine D3 receptor mRNA in a rodent model of behavioural sensitization to levodopa
  157. The Biochemical Bases for Reward
  158. Age and severity of nigrostriatal damage at onset of Parkinson's disease
  159. SCA-2 presenting as parkinsonism in an Alberta family: Clinical, genetic, and PET findings
  160. Dopamine release in human ventral striatum and expectation of reward
  161. Rett Syndrome: Investigation of Nine Patients, including PET Scan
  162. PET Study of the Effects of Valproate on Dopamine D 2 Receptors in Neuroleptic- and Mood-Stabilizer-Naive Patients With Nonpsychotic Mania
  163. Parkinsonʼs disease: imaging update
  164. “Stiff in the Closet” - Who Provides Care for Parkinsonian Patients?
  165. [18F]-Dopa positron emission tomography imaging in early-stage, non-parkin juvenile parkinsonism
  166. Blockade of nigral and pallidal opioid receptors suppresses vacuous chewing movements in a rodent model of tardive dyskinesia
  167. Somatostatin modulates the behavioral effects of dopamine receptor activation in parkinsonian rats
  168. The placebo effect in Parkinson's disease
  169. The placebo effect in neurological disorders
  170. PET Study of [ 18 F]6-Fluoro- l -Dopa Uptake in Neuroleptic- and Mood-Stabilizer-Naive First-Episode Nonpsychotic Mania: Effects of Treatment With Divalproex Sodium
  171. Bilateral human fetal striatal transplantation in Huntington's disease
  172. Alternating two finger tapping with contralateral activation is an objective measure of clinical severity in Parkinson's disease and correlates with PET [18F]-DOPA Ki
  173. Daytime somnolence in patients with Parkinson's disease
  174. Assessing the integrity of the dopamine system in Parkinson's disease: How best to do it?
  175. Positron emission tomography of dopamine pathways in familial Parkinsonian syndromes
  176. Expectation and Dopamine Release: Mechanism of the Placebo Effect in Parkinson's Disease
  177. Antisense strategies for the treatment of neurological disease
  178. Positron emission tomography in pallido-ponto-nigral degeneration (PPND) family (frontotemporal dementia with parkinsonism linked to chromosome 17 and point mutation in tau gene)
  179. Biochemical variations in the synaptic level of dopamine precede motor fluctuations in Parkinson's disease: PET evidence of increased dopamine turnover
  180. Pharmacodynamic modeling of oral levodopa in Parkinson's disease
  181. Dopamine D1A receptor function in a rodent model of tardive dyskinesia
  182. Effects of oligonucleotide antisense to dopamine D1A receptor messenger RNA in a rodent model of levodopa-induced dyskinesia
  183. Unilateral pallidotomy for reduction of parkinsonian pain
  184. Neuroreceptor imaging: new developments in PET and SPECT imaging of neuroreceptor binding (including dopamine transporters, vesicle transporters and post synaptic receptor sites)
  185. Effect of age on caudate dopaminergic function in idiopathic Parkinsonism
  186. Striatal D2 receptors in symptomatic and asymptomatic carriers of dopa-responsive dystonia measured with [11C]-raclopride and positron-emission tomography
  187. The effects of CCK-4 on dopamine D1 agonist-induced grooming are blocked by a CCKA receptor antagonist: Evidence for a novel CCK receptor subtype?
  188. Pallidotomy for tardive dyskinesia
  189. Effects of graft-derived dopaminergic innervation on the target neurons of patch and matrix compartments of the striatum
  190. The Neurotensin Antagonist SR 48692 Fails to Modify the Behavioural Responses to a Dopamine D1 Receptor Agonist in the Rat
  191. Which dopamine receptor(s) do we need for motor function? Lessons from gene targeting and translational blockade
  192. Effects of ethanol in a putative rodent model of tardive dyskinesia
  193. Behavioural evidence for cholecystokinin-dopamine D1 receptor interactions in the rat
  194. Absence of Mutations in Superoxide Dismutase and Catalase Genes in Patients With Parkinson's Disease
  195. Pharmacological characterization of grooming induced by a selective NK-1 tachykinin receptor agonist
  196. Environmental Exposures in Elderly Canadians With Parkinson’s Disease
  197. Effects of neurotensin in a rodent model of tardive dyskinesia
  198. Dopamine D1 receptor agonist-induced grooming is blocked by the opioid receptor antagonist naloxone
  199. Localization of striatal and nigral tachykinin receptors in the rat
  200. Effects of ageing on tachykinin function in the basal ganglia
  201. Neuroleptic-induced chewing movements in the rat are suppressed by peripherally but not centrally administered CCK and abolished by bilateral subdiaphragmatic vagotomy
  202. The opiate antagonist naloxone suppresses a rodent model of tardive dyskinesia
  203. Behavioural effects of selective tachykinin agonists in midbrain dopamine regions
  204. Neurotensin and neurotensin analogues modify the effects of chronic neuroleptic administration in the rat
  205. Autoradiographic visualization of NK-3 tachykinin binding sites in the rat brain, utilizing [3H]senktide
  206. Pharmacological characterization of the behavioral syndrome induced by the NK-3 tachykinin agonist senktide in rodents: evidence for mediation by endogenous 5-HT
  207. Effects of ageing on the behavioural responses to dopamine agonists: decreased yawning and locomotion, but increased stereotypy
  208. Chronic neuroleptic-induced mouth movements in the rat: suppression by CCK and selective dopamine D1 and D2 receptor antagonists
  209. The NK-3 tachykinin agonist senktide elicits yawning and chewing mouth movements following subcutaneous administration in the rat. Evidence for cholinergic mediation
  210. The NK-3 tachykinin receptor agonist senktide elicits 5-HT-mediated behaviour following central or peripheral administration in mice and rats
  211. Apomorphine-induced yawning in rats is abolished by bilateral 6-hydroxydopamine lesions of the substantia nigra
  212. Senktide, a selective neurokinin B-like agonist, elicits serotonin-mediated behaviour following intracisternal administration in the mouse
  213. Controlling for Cerebral Atrophy in Positron Emission Tomography Data
  214. Regression Model for Predicting Dissociations of Regional Cerebral Glucose Metabolism in Individuals at Risk for Huntington's Disease
  215. Dementia in Movement Disorders
  216. DOUBLE-BLIND STUDY OF BOTULINUM TOXIN IN SPASMODIC TORTICOLLIS
  217. Glucose Use Correlations: A Matter of Inference
  218. Cerebral metabolism of glucose in benign hereditary chorea
  219. (+)-4-PROPYL-9-HYDROXYNAPHTHOXAZINE (PHNO), A NEW DOPAMINOMIMETIC, IN TREATMENT OF PARKINSONISM
  220. Nemaline Myopathy With Associated Cardiomyopathy
  221. Positron emission tomography after MPTP: observations relating to the cause of Parkinson's disease
  222. Synthesis of thromboxane B2 and prostaglandins by bovine gastric mucosal microsomes
  223. Positron Emission Tomography in Parkinson’s Disease
  224. Neuroimaging of Parkinson's disease
  225. Imaging of the Parkinsonian Brain in Relation to Restorative Therapy
  226. Imaging of the Parkinsonian Brain in Relation to Restorative Therapy