All Stories

  1. Deficiency of heme oxygenase 1a causes detrimental effects on cardiac function

    Article • Journal of Cellular and Molecular Medicine, March 2024, Wiley

    Päivi Lakkisto

  2. miR‐619‐5p and cardiogenic shock in patients with ST‐segment elevation myocardial infarction

    Article • European Journal of Clinical Investigation, February 2024, Wiley

    Päivi Lakkisto

  3. Development of circulating microRNA-based biomarkers for medical decision-making: a friendly reminder of what should NOT be done

    Article • Critical Reviews in Clinical Laboratory Sciences, November 2022, Taylor & Francis

    Päivi Lakkisto

  4. Moderate hyperuricaemia ameliorated kidney damage in a low‐renin model of experimental renal insufficiency

    Article • Basic & Clinical Pharmacology & Toxicology, October 2022, Wiley

    Päivi Lakkisto

  5. Tankyrase Inhibition Attenuates Cardiac Dilatation and Dysfunction in Ischemic Heart Failure

    Article • International Journal of Molecular Sciences, September 2022, MDPI AG

    Päivi Lakkisto, Mikko I. Mäyränpää

  6. Alterations of Cardiac Protein Kinases in Cyclic Nucleotide-Dependent Signaling Pathways in Human Ischemic Heart Failure

    Article • Frontiers in Cardiovascular Medicine, June 2022, Frontiers

    Päivi Lakkisto, Mikko I. Mäyränpää

  7. MiR-185-5p regulates the development of myocardial fibrosis

    Article • Journal of Molecular and Cellular Cardiology, April 2022, Elsevier

    Päivi Lakkisto

  8. Consensus guidelines for the validation of qRT-PCR assays in clinical research by the CardioRNA consortium

    Article • Molecular Therapy — Methods & Clinical Development, March 2022, Elsevier

    Päivi Lakkisto

  9. GSK3β Serine 389 Phosphorylation Modulates Cardiomyocyte Hypertrophy and Ischemic Injury

    Article • International Journal of Molecular Sciences, December 2021, MDPI AG

    Päivi Lakkisto

  10. Zebrafish Heart Failure Models

    Article • Frontiers in Cell and Developmental Biology, May 2021, Frontiers

    Päivi Lakkisto

  11. Association of miR-21-5p, miR-122-5p, and miR-320a-3p with 90-Day Mortality in Cardiogenic Shock

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Päivi Lakkisto

  12. Two subphenotypes of septic acute kidney injury are associated with different 90-day mortality and renal recovery

    Article • Critical Care, April 2020, Springer Science + Business Media

    Päivi Lakkisto

  13. Unfavorable Reduction in the Ratio of Endothelin B to A Receptors in Experimental 5/6 Nephrectomy and Adenine Models of Chronic Renal Insufficiency

    Article • International Journal of Molecular Sciences, January 2020, MDPI AG

    Päivi Lakkisto

  14. Vezf1 regulates cardiac structure and contractile function

    Article • EBioMedicine, January 2020, Elsevier

    Päivi Lakkisto

  15. Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality: data from the FINNAKI observational study

    Article • Annals of Intensive Care, September 2019, Springer Science + Business Media

    Päivi Lakkisto

  16. The association of endothelial injury and systemic inflammation with perioperative myocardial infarction

    Article • Annals of Clinical Biochemistry International Journal of Laboratory Medicine, September 2019, SAGE Publications

    Päivi Lakkisto

  17. Circulating MiRNA Dynamics in ST-Segment Elevation Myocardial Infarction-driven Cardiogenic Shock

    Article • Revista Española de Cardiología (English Edition), September 2019, Elsevier

    Päivi Lakkisto

  18. Heme oxygenase-1 repeat polymorphism in septic acute kidney injury

    Article • PLOS One, May 2019, PLOS

    Päivi Lakkisto

  19. Inhibition of let-7c Regulates Cardiac Regeneration after Cryoinjury in Adult Zebrafish

    Article • Journal of Cardiovascular Development and Disease, April 2019, MDPI AG

    Päivi Lakkisto

  20. Catalyzing Transcriptomics Research in Cardiovascular Disease: The CardioRNA COST Action CA17129

    Article • Non-Coding RNA, March 2019, MDPI AG

    Päivi Lakkisto

  21. Circulating levels of microRNA 423-5p are associated with 90 day mortality in cardiogenic shock

    Article • ESC Heart Failure, November 2018, Wiley

    Päivi Lakkisto

  22. Characterizing the Key Metabolic Pathways of the Neonatal Mouse Heart Using a Quantitative Combinatorial Omics Approach

    Article • Frontiers in Physiology, April 2018, Frontiers

    Päivi Lakkisto

  23. Carbon monoxide releasing molecule improves structural and functional cardiac recovery after myocardial injury

    Article • European Journal of Pharmacology, January 2018, Elsevier

    Päivi Lakkisto

  24. Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset PreeclampsiaNovelty and Significance

    Article • Hypertension, December 2017, Wolters Kluwer Health

    Päivi Lakkisto

  25. Endothelin A receptor blocker and calcimimetic in the adenine rat model of chronic renal insufficiency

    Article • BMC Nephrology, October 2017, Springer Science + Business Media

    Päivi Lakkisto

  26. Sept7b is required for the subcellular organization of cardiomyocytes and cardiac function in zebrafish

    Article • AJP Heart and Circulatory Physiology, May 2017, American Physiological Society

    Päivi Lakkisto, Sanna Lehtonen

  27. Plasma Heme Oxygenase-1 in Patients Resuscitated from out-of-Hospital Cardiac Arrest

    Article • Shock, March 2016, Wolters Kluwer Health

    Päivi Lakkisto

  28. Urinary Biomarkers Indicative of Apoptosis and Acute Kidney Injury in the Critically Ill

    Article • PLOS One, February 2016, PLOS

    Päivi Lakkisto

  29. Human plasma cell-free DNA as a predictor of infectious complications of neutropenic fever in hematological patients

    Article • Infectious Diseases, February 2015, Taylor & Francis

    Päivi Lakkisto

  30. Microsatellite Polymorphism in the Heme Oxygenase-1 Promoter Is Associated With Nonsevere and Late-Onset Preeclampsia

    Article • Hypertension, May 2014, Wolters Kluwer Health

    Päivi Lakkisto

  31. Phosphate Binding Reduces Aortic Angiotensin-Converting Enzyme and Enhances Nitric Oxide Bioactivity in Experimental Renal Insufficiency

    Article • American Journal of Nephrology, January 2014, Karger Publishers

    Päivi Lakkisto

  32. Effects of angiotensin II blockade on cardiomyocyte regeneration after myocardial infarction in rats

    Article • Journal of the Renin-Angiotensin-Aldosterone System, April 2013, SAGE Publications

    Päivi Lakkisto

  33. VEGF overexpression improves mesenchymal stem cell sheet transplantation therapy for acute myocardial infarction

    Article • Journal of Tissue Engineering and Regenerative Medicine, March 2012, Wiley

    Päivi Lakkisto

  34. Dietary Phosphate Binding and Loading Alter Kidney Angiotensin-Converting Enzyme mRNA and Protein Content in 5/6 Nephrectomized Rats

    Article • American Journal of Nephrology, January 2012, Karger Publishers

    Päivi Lakkisto

  35. Heme oxygenase-1 induction protects the heart and modulates cellular and extracellular remodelling after myocardial infarction in rats

    Article • Experimental Biology and Medicine, December 2011, SAGE Publications

    Päivi Lakkisto

  36. Effects of Levosimendan on Cardiac Gene Expression Profile and Post-Infarct Cardiac Remodelling in Diabetic Goto-Kakizaki Rats

    Article • Basic & Clinical Pharmacology & Toxicology, August 2011, Wiley

    Päivi Lakkisto

  37. hHGF Overexpression in Myoblast Sheets Enhances Their Angiogenic Potential in Rat Chronic Heart Failure

    Article • PLOS One, April 2011, PLOS

    Päivi Lakkisto

  38. Plasma cell-free DNA in patients needing mechanical ventilation

    Article • Critical Care, January 2011, Springer Science + Business Media

    Päivi Lakkisto

  39. Heat shock attenuates VEGF expression in three-dimensional myoblast sheets deteriorating therapeutic efficacy in heart failure

    Article • Medical Science Monitor, January 2011, International Scientific Literature

    Päivi Lakkisto

  40. Heme Oxygenase 1 Polymorphisms and Plasma Concentrations in Critically Ill Patients

    Article • Shock, December 2010, Wolters Kluwer Health

    Päivi Lakkisto

  41. Heme oxygenase-1 and carbon monoxide promote neovascularization after myocardial infarction by modulating the expression of HIF-1α, SDF-1α and VEGF-B

    Article • European Journal of Pharmacology, June 2010, Elsevier

    Päivi Lakkisto

  42. Angiotensin receptors in the eyes of arterial hypertensive rats

    Article • Acta Ophthalmologica, September 2009, Wiley

    Päivi Lakkisto

  43. The heme oxygenase inducer hemin protects against cardiac dysfunction and ventricular fibrillation in ischaemic/reperfused rat hearts: role of connexin 43

    Article • Scandinavian Journal of Clinical and Laboratory Investigation, January 2009, Taylor & Francis

    Päivi Lakkisto

  44. Cell-Free Plasma DNA as a Predictor of Outcome in Severe Sepsis and Septic Shock

    Article • Clinical Chemistry, April 2008, AACC

    Päivi Lakkisto

  45. Activation of protective and damaging components of the cardiac renin-angiotensin system after myocardial infarction in experimental diabetes

    Article • Journal of the Renin-Angiotensin-Aldosterone System, June 2007, SAGE Publications

    Päivi Lakkisto

  46. Association of cell-free plasma DNA with hospital mortality and organ dysfunction in intensive care unit patients

    Article • Intensive Care Medicine, May 2007, Springer Science + Business Media

    Päivi Lakkisto

  47. Sustained cardiomyocyte apoptosis and left ventricular remodelling after myocardial infarction in experimental diabetes

    Article • Diabetologia, February 2004, Springer Science + Business Media

    Päivi Lakkisto

  48. Effect of vasopeptidase inhibitor omapatrilat on cardiomyocyte apoptosis and ventricular remodeling in rat myocardial infarction

    Article • Cardiovascular Research, March 2003, European Society of Cardiology

    Päivi Lakkisto

  49. Expression of Heme Oxygenase-1 in Response to Myocardial Infarction in Rats

    Article • Journal of Molecular and Cellular Cardiology, October 2002, Elsevier

    Päivi Lakkisto