All Stories

  1. Beyond ORBIT: Mapping the Constellation of Pseudomonas Endotypes in Bronchiectasis Clinical Trials

    Article • American Review of Respiratory Disease, August 2025, American Thoracic Society

    Dr Micheál Mac Aogáin

  2. Ever tried. Ever failed. No matter. The CFMATTERS study and the future of microbiome-directed trials in cystic fibrosis

    Article • European Respiratory Journal, August 2025, European Respiratory Society (ERS)

    Dr Micheál Mac Aogáin

  3. Accelerated Lung Function Decline and Mucus–Microbe Evolution in Chronic Obstructive Pulmonary Disease

    Article • American Review of Respiratory Disease, August 2024, American Thoracic Society

    Dr Micheál Mac Aogáin

  4. Unsung Heroes? Decoding the Protective Effects of Airway Microbiota in Chronic Obstructive Pulmonary Disease

    Article • American Review of Respiratory Disease, July 2024, American Thoracic Society

    Dr Micheál Mac Aogáin

  5. Airway “Resistotypes” and Clinical Outcomes in Bronchiectasis

    Article • American Review of Respiratory Disease, July 2024, American Thoracic Society

    Dr Micheál Mac Aogáin

  6. Infection and the microbiome in bronchiectasis

    Article • European Respiratory Review, July 2024, European Respiratory Society (ERS)

    Dr Micheál Mac Aogáin

  7. Targeting respiratory microbiomes in COPD and bronchiectasis

    Article • Expert Review of Respiratory Medicine, April 2024, Taylor & Francis

    Dr Micheál Mac Aogáin

  8. Reply to Ward et al.

    Article • American Review of Respiratory Disease, September 2023, American Thoracic Society

    Dr Micheál Mac Aogáin

  9. Microbial Dysregulation of the Gut-Lung Axis in Bronchiectasis

    Article • American Review of Respiratory Disease, April 2023, American Thoracic Society

    Professor Krasimira Tsaneva-Atanasova, Dr Micheál Mac Aogáin

  10. Bronchiectasis

    Article • January 2022, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  11. Aspergillus-Associated Endophenotypes in Bronchiectasis

    Article • Seminars in Respiratory and Critical Care Medicine, July 2021, Thieme Publishing Group

    Dr Micheál Mac Aogáin

  12. Similarity network fusion (SNF) for the integration of multi-omics and microbiomes in respiratory disease

    Article • European Respiratory Journal, June 2021, European Respiratory Society (ERS)

    Professor Krasimira Tsaneva-Atanasova, Dr Micheál Mac Aogáin

  13. On Bugs and Blowholes: Why Is Aspiration the Rule, Not the Exception?

    Article • American Review of Respiratory Disease, May 2021, American Thoracic Society

    Dr Micheál Mac Aogáin

  14. Integrative microbiomics in bronchiectasis exacerbations

    Article • Nature Medicine, April 2021, Springer Science + Business Media

    Professor Krasimira Tsaneva-Atanasova, Dr Micheál Mac Aogáin

  15. Metagenomics Reveals a Core Macrolide Resistome Related to Microbiota in Chronic Respiratory Disease

    Article • American Review of Respiratory Disease, August 2020, American Thoracic Society

    Professor Krasimira Tsaneva-Atanasova, Dr Micheál Mac Aogáin

  16. Increased Chitotriosidase Is Associated With Aspergillus and Frequent Exacerbations in South-East Asian Patients With Bronchiectasis

    Article • CHEST Journal, August 2020, Elsevier

    Dr Micheál Mac Aogáin

  17. “High-Risk” Clinical and Inflammatory Clusters in COPD of Chinese Descent

    Article • CHEST Journal, July 2020, Elsevier

    Professor Krasimira Tsaneva-Atanasova, Fanny Ko, Dr Micheál Mac Aogáin

  18. Environmental fungal sensitisation associates with poorer clinical outcomes in COPD

    Article • European Respiratory Journal, April 2020, European Respiratory Society (ERS)

    Fanny Ko, Dr Micheál Mac Aogáin

  19. Whole-Genome Sequencing of Aspergillus terreus Species Complex

    Article • Mycopathologia, February 2020, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  20. Reply to: Bacterial DNA in Fetal Lung Samples May Be Explained by Sample Contamination

    Article • American Review of Respiratory Disease, February 2020, American Thoracic Society

    Dr Micheál Mac Aogáin

  21. The Mycobiome in Health and Disease: Emerging Concepts, Methodologies and Challenges

    Article • Mycopathologia, January 2020, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  22. Airway microbiome composition correlates with lung function and arterial stiffness in an age-dependent manner

    Article • PLOS One, November 2019, PLOS

    Dr Micheál Mac Aogáin

  23. Optimisation and Benchmarking of Targeted Amplicon Sequencing for Mycobiome Analysis of Respiratory Specimens

    Article • International Journal of Molecular Sciences, October 2019, MDPI AG

    Dr Micheál Mac Aogáin

  24. MycopathologiaGENOMES: The New ‘Home’ for the Publication of Fungal Genomes

    Article • Mycopathologia, August 2019, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  25. Bronchiectasis and cough: An old relationship in need of renewed attention

    Article • Pulmonary Pharmacology & Therapeutics, August 2019, Elsevier

    Dr Micheál Mac Aogáin

  26. Distinct “Immunoallertypes” of Disease and High Frequencies of Sensitization in Non–Cystic Fibrosis Bronchiectasis

    Article • American Review of Respiratory Disease, April 2019, American Thoracic Society

    Dr Micheál Mac Aogáin

  27. Intercontinental translocation of latent multidrug‐resistant tuberculosis to Australia demonstrated by whole genome sequencing

    Article • The Medical Journal of Australia, February 2019, Wiley

    Dr Micheál Mac Aogáin

  28. Inhaled nanomaterials and the respiratory microbiome: clinical, immunological and toxicological perspectives

    Article • Particle and Fibre Toxicology, November 2018, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  29. Immunological corollary of the pulmonary mycobiome in bronchiectasis: the CAMEB study

    Article • European Respiratory Journal, June 2018, European Respiratory Society (ERS)

    Dr Micheál Mac Aogáin

  30. Antimicrobial resistance and molecular epidemiology using whole-genome sequencing of Neisseria gonorrhoeae in Ireland, 2014–2016: focus on extended-spectrum cephalosporins and azithromycin

    Article • European Journal of Clinical Microbiology & Infectious Diseases, June 2018, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  31. Geographic variation in the aetiology, epidemiology and microbiology of bronchiectasis

    Article • BMC Pulmonary Medicine, May 2018, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  32. Field of genes: using Apache Kafka as a bioinformatic data repository

    Article • GigaScience, April 2018, Oxford University Press (OUP)

    Dr Micheál Mac Aogáin

  33. The Microbial Endocrinology of Pseudomonas aeruginosa: Inflammatory and Immune Perspectives

    Article • Archivum Immunologiae et Therapiae Experimentalis, March 2018, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  34. Molecular epidemiology of tuberculosis in Tasmania and genomic characterisation of its first known multi-drug resistant case

    Article • PLOS One, February 2018, PLOS

    Dr Micheál Mac Aogáin

  35. Draft Genome Sequence of the First Confirmed Isolate of Multidrug-Resistant Mycobacterium tuberculosis in Tasmania

    Article • Genome Announcements, November 2017, ASM Journals

    Dr Micheál Mac Aogáin, Ronan O'Toole

  36. Fourteen Draft Genome Sequences for the First Reported Cases of Azithromycin-Resistant Neisseria gonorrhoeae in Ireland

    Article • Genome Announcements, June 2017, ASM Journals

    Dr Micheál Mac Aogáin

  37. Differential carriage of virulence-associated loci in the New Zealand Rangipo outbreak strain of Mycobacterium tuberculosis

    Article • Infectious Diseases, May 2017, Taylor & Francis

    Dr Micheál Mac Aogáin, Ronan O'Toole

  38. The role of acute and chronic respiratory colonization and infections in the pathogenesis of COPD

    Article • Respirology, March 2017, Wiley

    Dr Micheál Mac Aogáin

  39. Understanding COPD-overlap syndromes

    Article • Expert Review of Respiratory Medicine, March 2017, Taylor & Francis

    Dr Micheál Mac Aogáin

  40. Microbiomes in respiratory health and disease: An Asia-Pacific perspective

    Article • Respirology, January 2017, Wiley

    Dr Shakti Dhar Shukla, Dr Micheál Mac Aogáin

  41. Draft Genome Sequence of a New Zealand Rangipo Strain of Mycobacterium tuberculosis

    Article • Genome Announcements, July 2016, ASM Journals

    Dr Micheál Mac Aogáin

  42. Possible Interplay Between Hospital and Community Transmission of a Novel Clostridium Difficile Sequence Type 295 Recognized by Next-Generation Sequencing

    Article • Infection Control, April 2016, Cambridge University Press

    Dr Micheál Mac Aogáin

  43. Characterization of Escherichia coli bloodstream isolates associated with mortality

    Article • Journal of Medical Microbiology, January 2016, Society for General Microbiology

    Dr Micheál Mac Aogáin

  44. Identification of emergent blaCMY-2-carrying Proteus mirabilis lineages by whole-genome sequencing

    Article • New Microbes and New Infections, January 2016, Elsevier

    Dr Micheál Mac Aogáin

  45. A first glance at the genome of Mycobacterium chimeara - a pathogen of renewed clinical importance

    Article • Genome Announcements, December 2015, ASM Journals

    Dr Micheál Mac Aogáin

  46. Identification of a novel mutation at the primary dimer interface of GyrA conferring fluoroquinolone resistance in Clostridium difficile

    Article • Journal of Global Antimicrobial Resistance, December 2015, Elsevier

    Dr Micheál Mac Aogáin

  47. Typhlocolitis associated with Clostridium difficile ribotypes 078 and 110 in neonatal piglets from a commercial Irish pig herd

    Article • Irish Veterinary Journal, December 2015, Springer Science + Business Media

    Dr Micheál Mac Aogáin

  48. Enhanced Tracking of Nosocomial Transmission of Endemic Sequence Type 22 Methicillin-Resistant Staphylococcus aureus Type IV Isolates among Patients and Environmental Sites by Use of Whole-Genome Sequencing

    Article • Journal of Clinical Microbiology, November 2015, ASM Journals

    David C Coleman, Dr Micheál Mac Aogáin

  49. Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection

    Article • PLoS Pathogens, November 2015, PLOS

    Dr Micheál Mac Aogáin, Joan A Geoghegan

  50. Whole-genome sequencing improves discrimination of relapse from reinfection and identifies transmission events among patients with recurrent Clostridium difficile infections

    Article • Journal of Hospital Infection, June 2015, Elsevier

    Dr Micheál Mac Aogáin

  51. Draft Genome Sequence of a Drug-Susceptible New Zealand Isolate of Mycobacterium tuberculosis Lineage 3

    Article • Genome Announcements, May 2015, ASM Journals

    Dr Micheál Mac Aogáin, Ronan O'Toole

  52. Detailed characterization of the first high-level azithromycin-resistant Neisseria gonorrhoeae cases in Ireland: Table 1.

    Article • Journal of Antimicrobial Chemotherapy, April 2015, Oxford University Press (OUP)

    Dr Micheál Mac Aogáin

  53. Draft Genome Sequence of a Multidrug-Resistant New Zealand Isolate of Mycobacterium tuberculosis Lineage 3

    Article • Genome Announcements, October 2014, ASM Journals

    Dr Micheál Mac Aogáin, Ronan O'Toole

  54. Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in Ireland

    Article • Genome Announcements, October 2014, ASM Journals

    Ms Emma Roycroft, Dr Micheál Mac Aogáin

  55. Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant Mycobacterium tuberculosis in New Zealand

    Article • Genome Announcements, May 2014, ASM Journals

    Dr Micheál Mac Aogáin

  56. The non-classical ArsR-family repressor PyeR (PA4354) modulates biofilm formation in Pseudomonas aeruginosa

    Article • Microbiology, July 2012, Society for General Microbiology

    Dr Micheál Mac Aogáin

  57. Characterization of imipenem resistance mechanisms in Pseudomonas aeruginosa isolates from Turkey

    Article • Clinical Microbiology and Infection, July 2012, Elsevier

    Dr Micheál Mac Aogáin

  58. MexT Functions as a Redox-Responsive Regulator Modulating Disulfide Stress Resistance in Pseudomonas aeruginosa

    Article • Journal of Bacteriology, April 2012, ASM Journals

    Dr Micheál Mac Aogáin

  59. Emergence of extended-spectrum β-lactamase and fluoroquinolone resistance genes among Irish multidrug-resistant isolates

    Article • Diagnostic Microbiology and Infectious Disease, May 2010, Elsevier

    Dr Micheál Mac Aogáin

  60. Transcriptome profiling defines a novel regulon modulated by the LysR-type transcriptional regulator MexT in Pseudomonas aeruginosa

    Article • Nucleic Acids Research, October 2009, Oxford University Press (OUP)

    Dr Micheál Mac Aogáin

  61. MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump

    Article • Microbial Pathogenesis, October 2009, Elsevier

    Dr Micheál Mac Aogáin