All Stories

  1. Omecamtiv mecarbil and Mavacamten target the same myosin pocket despite opposite effects in heart contraction

    Article • Nature Communications, June 2024, Springer Science + Business Media

    Professor Hans-Joachim Knölker

  2. Synthesis of 1,1′‐Bicarbazoles by Sequential Iron(III)‐ and Palladium(II)‐Catalyzed Oxidative Coupling Reactions**

    Article • Chemistry - A European Journal, February 2024, Wiley

    Professor Hans-Joachim Knölker

  3. 2,2′‐Bis(arylamino)‐1,1′‐biaryls as Building Blocks for the Synthesis of Dibenzo[d,f][1,3]diazepines, Dibenzo[d,f][1,3]diazepinones, and Dibenzo[c,e][1,2,7]thiadiazepine 6‐Oxides

    Article • European Journal of Organic Chemistry, August 2023, Wiley

    Professor Hans-Joachim Knölker

  4. Changes in lipid metabolism driven by steroid signalling modulate proteostasis in C. elegans

    Article • EMBO Reports, April 2023, EMBO

    Professor Hans-Joachim Knölker

  5. μ-Oxo-bis[(octacosafluoro-meso-tetraphenylporphyrinato)iron(iii)] – synthesis, crystal structure, and catalytic activity in oxidation reactions

    Article • Chemical Science, January 2023, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  6. Atroposelective Synthesis of 2,2′‐Bis(arylamino)‐1,1′‐biaryls by Oxidative Iron(III)‐ and Phosphoric Acid‐Catalyzed C−C Coupling of Diarylamines**

    Article • Chemistry - A European Journal, November 2022, Wiley

    Professor Hans-Joachim Knölker

  7. First Synthesis, Confirmation of Stereochemistry, and Cytotoxic Activity of Oxyfungiformin

    Article • European Journal of Organic Chemistry, September 2022, Wiley

    Professor Hans-Joachim Knölker

  8. Palladium‐Catalyzed Synthesis of Alkylcarbazoles and Their Identification in Petroleum and Source Rocks**

    Article • European Journal of Organic Chemistry, June 2022, Wiley

    Professor Hans-Joachim Knölker

  9. Iron‐Catalyzed Oxidative C−O and C−N Coupling Reactions Using Air as Sole Oxidant**

    Article • Chemistry - A European Journal, March 2022, Wiley

    Professor Hans-Joachim Knölker

  10. Preface

    Article • January 2022, Elsevier

    Professor Hans-Joachim Knölker

  11. Preface

    Article • January 2022, Elsevier

    Professor Hans-Joachim Knölker

  12. Myosin 1c: A novel regulator of glucose uptake in brown adipocytes

    Article • Molecular Metabolism, November 2021, Elsevier

    Professor Hans-Joachim Knölker

  13. Mechanistic Studies on the Hexadecafluorophthalocyanine–Iron‐Catalyzed Wacker‐Type Oxidation of Olefins to Ketones**

    Article • Chemistry - A European Journal, October 2021, Wiley

    Professor Hans-Joachim Knölker

  14. Isolation and structure elucidation of pyridine alkaloids from the aerial parts of the Mongolian medicinal plant Caryopteris mongolica Bunge

    Article • Scientific Reports, July 2021, Springer Science + Business Media

    Professor Hans-Joachim Knölker

  15. Loss of Motor Protein MYO1C Causes Rhodopsin Mislocalization and Results in Impaired Visual Function

    Article • Cells, May 2021, MDPI AG

    Professor Hans-Joachim Knölker

  16. Iron‐Catalyzed Wacker‐type Oxidation of Olefins at Room Temperature with 1,3‐Diketones or Neocuproine as Ligands**

    Article • Angewandte Chemie, May 2021, Wiley

    Professor Hans-Joachim Knölker

  17. Iron‐Catalyzed Wacker‐type Oxidation of Olefins at Room Temperature with 1,3‐Diketones or Neocuproine as Ligands**

    Article • Angewandte Chemie, May 2021, Wiley

    Professor Hans-Joachim Knölker

  18. UHPLC-IM-Q-ToFMS analysis of maradolipids, found exclusively in Caenorhabditis elegans dauer larvae

    Article • Analytical and Bioanalytical Chemistry, February 2021, Springer Science + Business Media

    Professor Hans-Joachim Knölker

  19. Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes

    Article • Journal of Cell Biology, January 2021, Rockefeller University Press

    Professor Hans-Joachim Knölker

  20. In vitro and in vivo effects of inhibitors on actin and myosin

    Article • Bioorganic & Medicinal Chemistry, January 2021, Elsevier

    Professor Hans-Joachim Knölker

  21. Preface

    Article • January 2021, Elsevier

    Professor Hans-Joachim Knölker

  22. Preface

    Article • January 2021, Elsevier

    Professor Hans-Joachim Knölker

  23. First Total Synthesis and Investigation of the X-ray Crystal Structure of the Pyrano[3,2-a]carbazole Alkaloid Clausenalansine A

    Article • Synthesis, November 2020, Thieme Publishing Group

    Professor Hans-Joachim Knölker

  24. Development and Technical Validation of an Immunoassay for the Detection of APP669–711 (Aβ−3–40) in Biological Samples

    Article • International Journal of Molecular Sciences, September 2020, MDPI AG

    Professor Hans-Joachim Knölker, Oliver Wirths

  25. Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines

    Article • Frontiers in Immunology, September 2020, Frontiers

    Professor Hans-Joachim Knölker

  26. Synthesis of Clausenal, 1,5‐Dimethoxycarbazole‐3‐carbaldehyde and 2,5‐Dimethoxycarbazole‐3‐carbaldehyde

    Article • European Journal of Organic Chemistry, August 2020, Wiley

    Professor Hans-Joachim Knölker

  27. Iron-Catalyzed Synthesis, Structure, and Photophysical Properties of Tetraarylnaphthidines

    Article • Molecules, April 2020, MDPI AG

    Professor Hans-Joachim Knölker

  28. Iron‐Catalyzed Oxidative C−C Cross‐Coupling Reaction of Tertiary Anilines with Hydroxyarenes by Using Air as Sole Oxidant

    Article • Chemistry - A European Journal, February 2020, Wiley

    Professor Hans-Joachim Knölker

  29. Outstanding Reviewers for Organic & Biomolecular Chemistry in 2019

    Article • Organic & Biomolecular Chemistry, January 2020, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  30. Preface

    Article • January 2020, Elsevier

    Professor Hans-Joachim Knölker

  31. Preface

    Article • January 2020, Elsevier

    Professor Hans-Joachim Knölker

  32. Synthesis and Crystal Structure of Dimorphic Dibenzo[ cde , opq ]rubicene

    Article • Chemistry - A European Journal, September 2019, Wiley

    Professor Hans-Joachim Knölker

  33. Pentachloropseudilin Impairs Angiogenesis by Disrupting the Actin Cytoskeleton, Integrin Trafficking and the Cell Cycle

    Article • ChemBioChem, August 2019, Wiley

    Professor Hans-Joachim Knölker

  34. The motor protein Myo1c regulates transforming growth factor-β–signaling and fibrosis in podocytes

    Article • Kidney International, July 2019, Elsevier

    Professor Hans-Joachim Knölker

  35. Opposing steroid signals modulate protein homeostasis through deep changes in fat metabolism in Caenorhabditis elegans

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Professor Hans-Joachim Knölker

  36. Preface

    Article • January 2019, Elsevier

    Professor Hans-Joachim Knölker

  37. Preface

    Article • January 2019, Elsevier

    Professor Hans-Joachim Knölker

  38. Enantioselective Total Synthesis and Assignment of the Absolute Configuration of the Furo[3,2-a]carbazole Alkaloid Furoclausine-B

    Article • The Journal of Organic Chemistry, November 2018, American Chemical Society (ACS)

    Professor Hans-Joachim Knölker

  39. Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure

    Article • Frontiers in Immunology, September 2018, Frontiers

    Professor Hans-Joachim Knölker

  40. Synthesis of Euchrestifoline Using Iron- and Palladium-Catalyzed C-H Bond Activations

    Article • European Journal of Organic Chemistry, August 2018, Wiley

    Professor Hans-Joachim Knölker

  41. Synthesis and Activity against Mycobacterium tuberculosis of Olivacine and Oxygenated Derivatives

    Article • Molecules, June 2018, MDPI AG

    Professor Hans-Joachim Knölker

  42. Synthesis and Activity Against <em>Mycobacterium tuberculosis</em> of Olivacine and Oxygenated Derivatives

    Article • June 2018, MDPI AG

    Professor Hans-Joachim Knölker

  43. Synthesis and Anti-Tuberculosis Activity of Olivacine and Oxygenated Derivatives

    Article • May 2018, MDPI AG

    Professor Hans-Joachim Knölker

  44. Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves

    Article • Scientific Reports, April 2018, Springer Science + Business Media

    Professor Hans-Joachim Knölker

  45. First Total Synthesis of 7-Isovaleryloxy-8-methoxygirinimbine

    Article • Synthesis, April 2018, Thieme Publishing Group

    Professor Hans-Joachim Knölker

  46. Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics

    Article • Journal of Cell Biology, March 2018, Rockefeller University Press

    Professor Hans-Joachim Knölker

  47. Pentachloropseudilin Inhibits Transforming Growth Factor-β (TGF-β) Activity by Accelerating Cell-Surface Type II TGF-β Receptor Turnover in Target Cells

    Article • ChemBioChem, March 2018, Wiley

    Professor Hans-Joachim Knölker

  48. Decoding Allosteric Networks in Biocatalysts: Rational Approach to Therapies and Biotechnologies

    Article • ACS Catalysis, February 2018, American Chemical Society (ACS)

    Professor Hans-Joachim Knölker

  49. Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity

    Article • Journal of Enzyme Inhibition and Medicinal Chemistry, January 2018, Taylor & Francis

    Professor Hans-Joachim Knölker

  50. Preface

    Article • January 2018, Elsevier

    Professor Hans-Joachim Knölker

  51. Preface

    Article • January 2018, Elsevier

    Professor Hans-Joachim Knölker

  52. Conversion of Olefins into Ketones by an Iron-Catalyzed Wacker-type Oxidation Using Oxygen as the Sole Oxidant

    Article • Angewandte Chemie, December 2017, Wiley

    Professor Hans-Joachim Knölker

  53. Conversion of Olefins into Ketones by an Iron-Catalyzed Wacker-type Oxidation Using Oxygen as the Sole Oxidant

    Article • Angewandte Chemie, December 2017, Wiley

    Professor Hans-Joachim Knölker

  54. Synthesis of 1,1′- and 2,2′-Bicarbazole Alkaloids by Iron(III)-Catalyzed Oxidative Coupling of 2- and 1-Hydroxycarbazoles

    Article • Chemistry - A European Journal, December 2017, Wiley

    Professor Hans-Joachim Knölker

  55. Synthesis of Tetranuclear Palladium(II) Complexes and Their Catalytic Activity for Cross-Coupling Reactions

    Article • Chemistry - A European Journal, November 2017, Wiley

    Professor Hans-Joachim Knölker

  56. Anti-tuberculosis activity and structure–activity relationships of oxygenated tricyclic carbazole alkaloids and synthetic derivatives

    Article • Bioorganic & Medicinal Chemistry, November 2017, Elsevier

    Professor Hans-Joachim Knölker

  57. Reductive Eliminations from Diarylpalladium(II) Complexes: A Combined Experimental and Computational Investigation

    Article • Chemistry - A European Journal, October 2017, Wiley

    Professor Hans-Joachim Knölker

  58. Quantitative Structure-Retention Relationships for Polycyclic Aromatic Hydrocarbons and their Oligoalkynyl-Substituted Derivatives

    Article • ChemistryOpen, July 2017, Wiley

    Professor Hans-Joachim Knölker

  59. Isolation and structure elucidation of natural products of three soft corals and a sponge from the coast of Madagascar

    Article • Organic & Biomolecular Chemistry, January 2017, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  60. Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar

    Article • Organic & Biomolecular Chemistry, January 2016, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  61. Regioselective prenylation of bromocarbazoles by palladium(0)-catalysed cross coupling – synthesis of O-methylsiamenol, O-methylmicromeline and carquinostatin A

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  62. First total syntheses of chrestifoline-B and (±)-chrestifoline-C, and improved synthetic routes to bismurrayafoline-A, bismurrayafolinol and chrestifoline-D

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  63. Palladium(ii)-catalysed total synthesis of naturally occurring pyrano[3,2-a]carbazole and pyrano[2,3-b]carbazole alkaloids

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Hans-Joachim Knölker

  64. Total synthesis of the cyclic monoterpenoid pyrano[3,2-a]carbazole alkaloids derived from 2-hydroxy-6-methylcarbazole

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Professor Hans-Joachim Knölker