All Stories

  1. Early Alzheimer´s disease blood biomarkers are associated with a higher risk for postoperative long‐term cognitive decline: Insights from the FINDERI study

    Article • Alzheimer s & Dementia, July 2026, Wiley

    Oliver Wirths

  2. Evaluation of fully automated ApoE4 proteotyping for APOE ε4 genotype estimation in the FINDERI cohort

    Article • Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring, April 2026, Wiley

    Oliver Wirths

  3. Aggregation-dependent epitope sequence and modification fingerprints of anti-Aβ antibodies

    Article • eLife, February 2026, eLife

    Oliver Wirths

  4. Amyloid Plaques Ameliorate Memory Deficits and Hippocampal Neuron Loss in an Aβ4-42-Driven Alzheimer’s Disease Mouse Model

    Article • Molecular Neurobiology, January 2026, Springer Science + Business Media

    Oliver Wirths

  5. Characterization of a pathogenic gain-of-function mutation in the N-terminal domain of STAT1 which is reported to be associated with eosinophilic esophagitis

    Article • Cell Communication and Signaling, August 2025, Springer Science + Business Media

    Oliver Wirths

  6. Behavioral assessment and gene expression changes in a mouse model with dysfunctional STAT1 signaling

    Article • Cell Communication and Signaling, July 2025, Springer Science + Business Media

    Oliver Wirths

  7. N-terminal truncation of STAT1 transcription factor causes CD3- and CD20-negative non-Hodgkin lymphoma through upregulation of STAT3-mediated oncogenic functions

    Article • Cell Communication and Signaling, April 2025, Springer Science + Business Media

    Oliver Wirths

  8. Cognitive decline and neuroinflammation in a mouse model of obesity: An accelerating role of ageing

    Article • Brain Behavior and Immunity, March 2025, Elsevier

    Oliver Wirths

  9. Social inhibition in depressed patients is associated with an altered activation profile of the interleukin-6-inducible transcription factor STAT3

    Article • Brain Behavior & Immunity - Health, March 2025, Elsevier

    Oliver Wirths

  10. Caffeine and potential use in Alzheimer’s disease

    Article • January 2025, Elsevier

    Oliver Wirths

  11. Identification of isoAsp7-Aβ as a major Aβ variant in Alzheimer’s disease, dementia with Lewy bodies and vascular dementia

    Article • Acta Neuropathologica, December 2024, Springer Science + Business Media

    Oliver Wirths

  12. Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis

    Article • Immunity, November 2024, Elsevier

    Dr Andrew Octavian Sasmita, Oliver Wirths

  13. Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer’s disease model mice

    Article • Nature Neuroscience, August 2024, Springer Science + Business Media

    Dr Andrew Octavian Sasmita, Oliver Wirths

  14. Amino‐terminally elongated Aβ peptides are generated by the secreted metalloprotease ADAMTS4 and deposit in a subset of Alzheimer's disease brains

    Article • Neuropathology and Applied Neurobiology, June 2024, Wiley

    Oliver Wirths

  15. Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer’s disease

    Article • European Archives of Psychiatry and Clinical Neuroscience, February 2024, Springer Science + Business Media

    Oliver Wirths

  16. Blood plasma biomarkers for Alzheimer’s disease: Aβ1–42/1–40 vs. AβX–42/X–40

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), October 2023, De Gruyter

    Oliver Wirths

  17. A novel interface between the N-terminal and coiled-coil domain of STAT1 functions in an auto-inhibitory manner

    Article • Cell Communication and Signaling, July 2023, Springer Science + Business Media

    Oliver Wirths

  18. Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease

    Article • Nature, May 2023, Springer Science + Business Media

    Dr Andrew Octavian Sasmita, Oliver Wirths

  19. Brain Region-Specific Differences in Amyloid-β Plaque Composition in 5XFAD Mice

    Article • Life, April 2023, MDPI AG

    Oliver Wirths

  20. Lack of STAT1 co-operative DNA binding protects against adverse cardiac remodelling in acute myocardial infarction

    Article • Frontiers in Cardiovascular Medicine, February 2023, Frontiers

    Oliver Wirths

  21. Matrix Development for the Detection of Phosphorylated Amyloid-β Peptides by MALDI-TOF-MS

    Article • Journal of the American Society for Mass Spectrometry, January 2023, American Chemical Society (ACS)

    Oliver Wirths

  22. A Combination of Caffeine Supplementation and Enriched Environment in an Alzheimer’s Disease Mouse Model

    Article • International Journal of Molecular Sciences, January 2023, MDPI AG

    Oliver Wirths

  23. Is plasma amyloid-β 1–42/1–40 a better biomarker for Alzheimer’s disease than AβX–42/X–40?

    Article • Fluids and Barriers of the CNS, December 2022, Springer Science + Business Media

    Oliver Wirths

  24. Evaluation of the putative lymphoma-associated point mutation D427H in the STAT3 transcription factor

    Article • BMC Molecular and Cell Biology, June 2022, Springer Science + Business Media

    Oliver Wirths

  25. Combined long-term enriched environment and caffeine supplementation improve memory function in C57Bl6 mice

    Article • European Archives of Psychiatry and Clinical Neuroscience, June 2022, Springer Science + Business Media

    Oliver Wirths

  26. An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form

    Article • Cell Communication and Signaling, March 2022, Springer Science + Business Media

    Oliver Wirths

  27. Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer’s disease

    Article • Cellular and Molecular Life Sciences, March 2022, Springer Science + Business Media

    Steffen E. Storck, Oliver Wirths

  28. Detection and quantification of Aβ−3–40 (APP669‐711) in cerebrospinal fluid

    Article • Journal of Neurochemistry, January 2022, Wiley

    Oliver Wirths

  29. Long-term caffeine treatment of Alzheimer mouse models ameliorates behavioural deficits and neuron loss and promotes cellular and molecular markers of neurogenesis

    Article • Cellular and Molecular Life Sciences, December 2021, Springer Science + Business Media

    Oliver Wirths

  30. Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy

    Article • Nature Communications, November 2021, Springer Science + Business Media

    Oliver Wirths

  31. The anti-parallel dimer binding interface in STAT3 transcription factor is required for the inactivation of cytokine-mediated signal transduction

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, November 2021, Elsevier

    Oliver Wirths

  32. A microRNA signature that correlates with cognition and is a target against cognitive decline

    Article • EMBO Molecular Medicine, October 2021, Springer Science + Business Media

    Oliver Wirths

  33. Characterization of a Mouse Model of Alzheimer’s Disease Expressing Aβ4-42 and Human Mutant Tau

    Article • International Journal of Molecular Sciences, May 2021, MDPI AG

    Oliver Wirths

  34. Evaluation of cerebrospinal fluid glycoprotein NMB (GPNMB) as a potential biomarker for Alzheimer’s disease

    Article • Alzheimer s Research & Therapy, May 2021, Springer Science + Business Media

    Oliver Wirths

  35. Physical activity and cognitive stimulation ameliorate learning and motor deficits in a transgenic mouse model of Alzheimer’s disease

    Article • Behavioural Brain Research, January 2021, Elsevier

    Oliver Wirths

  36. Alzheimer’s Disease

    Article • January 2021, Springer Science + Business Media

    Oliver Wirths

  37. Immunotherapy Targeting Amyloid-ß Peptides in Alzheimer’s Disease

    Article • December 2020, Biogenic Press

    Oliver Wirths

  38. Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models

    Article • International Journal of Molecular Sciences, October 2020, MDPI AG

    Oliver Wirths

  39. Chronic Memantine Treatment Ameliorates Behavioral Deficits, Neuron Loss, and Impaired Neurogenesis in a Model of Alzheimer’s Disease

    Article • Molecular Neurobiology, September 2020, Springer Science + Business Media

    Oliver Wirths

  40. Development and Technical Validation of an Immunoassay for the Detection of APP669–711 (Aβ−3–40) in Biological Samples

    Article • International Journal of Molecular Sciences, September 2020, MDPI AG

    Professor Hans-Joachim Knölker, Oliver Wirths

  41. N‐terminal heterogeneity of parenchymal and vascular amyloid‐β deposits in Alzheimer’s disease

    Article • Neuropathology and Applied Neurobiology, June 2020, Wiley

    Oliver Wirths

  42. Loss of Hippocampal Calretinin and Parvalbumin Interneurons in the 5XFAD Mouse Model of Alzheimer’s Disease

    Article • ASN NEURO, January 2020, Taylor & Francis

    Oliver Wirths

  43. Emerging roles of N- and C-terminally truncated Aβ species in Alzheimer’s disease

    Article • Expert Opinion on Therapeutic Targets, December 2019, Taylor & Francis

    Oliver Wirths

  44. N-Terminally Truncated Aß Peptide Variants in Alzheimer’s Disease

    Article • November 2019, Codon Publications

    Oliver Wirths

  45. N-Terminal Truncated Aβ4-42 Is a Substrate for Neprilysin Degradation in vitro and in vivo

    Article • Journal of Alzheimer’s Disease, February 2019, IOS Press

    Oliver Wirths

  46. Physical Activity Ameliorates Impaired Hippocampal Neurogenesis in the Tg4-42 Mouse Model of Alzheimer’s Disease

    Article • ASN NEURO, January 2019, SAGE Publications

    Oliver Wirths

  47. A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease

    Article • Alzheimer s Research & Therapy, December 2018, Springer Science + Business Media

    Oliver Wirths

  48. The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease

    Article • Acta Neuropathologica, November 2018, Springer Science + Business Media

    Oliver Wirths, Steffen E. Storck

  49. Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

    Article • Acta Neuropathologica Communications, October 2018, Springer Science + Business Media

    Oliver Wirths

  50. The presubiculum is preserved from neurodegenerative changes in Alzheimer’s disease

    Article • Acta Neuropathologica Communications, July 2018, Springer Science + Business Media

    Oliver Wirths

  51. Synergistic Effect on Neurodegeneration by N-Truncated Aβ4−42 and Pyroglutamate Aβ3−42 in a Mouse Model of Alzheimer's Disease

    Article • Frontiers in Aging Neuroscience, March 2018, Frontiers

    Oliver Wirths

  52. N-truncated Aβ4–x peptides in sporadic Alzheimer’s disease cases and transgenic Alzheimer mouse models

    Article • Alzheimer s Research & Therapy, October 2017, Springer Science + Business Media

    Oliver Wirths

  53. Altered neurogenesis in mouse models of Alzheimer disease

    Article • Neurogenesis, January 2017, Taylor & Francis

    Oliver Wirths, Oliver Wirths

  54. Extraction of Soluble and Insoluble Protein Fractions from Mouse Brains and Spinal Cords

    Article • BIO-PROTOCOL, January 2017, Bio-Protocol, LLC

    Oliver Wirths

  55. Preparation of Crude Synaptosomal Fractions from Mouse Brains and Spinal Cords

    Article • BIO-PROTOCOL, January 2017, Bio-Protocol, LLC

    Oliver Wirths

  56. Effects of Long-Term Environmental Enrichment on Anxiety, Memory, Hippocampal Plasticity and Overall Brain Gene Expression in C57BL6 Mice

    Article • Frontiers in Molecular Neuroscience, August 2016, Frontiers

    Oliver Wirths

  57. Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model

    Article • Translational Psychiatry, May 2016, Springer Science + Business Media

    Oliver Wirths

  58. Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer’s disease and transgenic mouse models

    Article • Acta Neuropathologica Communications, March 2016, Springer Science + Business Media

    Oliver Wirths

  59. The Cannabinoid CB1/CB2 Agonist WIN55212.2 Promotes Oligodendrocyte DifferentiationIn Vitroand Neuroprotection During the Cuprizone-Induced Central Nervous System Demyelination

    Article • CNS Neuroscience & Therapeutics, February 2016, Wiley

    Oliver Wirths

  60. Endogenous Apolipoprotein E (ApoE) Fragmentation Is Linked to Amyloid Pathology in Transgenic Mouse Models of Alzheimer’s Disease

    Article • Molecular Neurobiology, January 2016, Springer Science + Business Media

    Oliver Wirths

  61. Alzheimer’s Disease

    Article • January 2016, Springer Science + Business Media

    Oliver Wirths

  62. Immunotherapy Against N-Truncated Amyloid-β Oligomers

    Article • January 2016, Springer Science + Business Media

    Oliver Wirths

  63. Gene Expression Profiling in the APP/PS1KI Mouse Model of Familial Alzheimer’s Disease

    Article • Journal of Alzheimer’s Disease, November 2015, IOS Press

    Oliver Wirths

  64. N-Truncated Aβ2-X Starting with Position Two in Sporadic Alzheimer’s Disease Cases and Two Alzheimer Mouse Models

    Article • Journal of Alzheimer’s Disease, September 2015, IOS Press

    Oliver Wirths

  65. Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease

    Article • Journal of Alzheimer’s Disease, April 2015, IOS Press

    Oliver Wirths

  66. Neprilysin Deficiency Alters the Neuropathological and Behavioral Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease

    Article • Journal of Alzheimer’s Disease, February 2015, IOS Press

    Oliver Wirths

  67. I716F AβPP Mutation Associates with the Deposition of Oligomeric Pyroglutamate Amyloid-β and α-Synucleinopathy with Lewy Bodies

    Article • Journal of Alzheimer’s Disease, January 2015, IOS Press

    Oliver Wirths

  68. Immunocytochemical Detection of Intraneuronal Aβ Peptides in Mouse Models of Alzheimer’s Disease

    Article • January 2015, Springer Science + Business Media

    Oliver Wirths

  69. Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Aβ accumulation

    Article • Frontiers in Aging Neuroscience, June 2014, Frontiers

    Oliver Wirths

  70. Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease

    Article • Acta Neuropathologica, May 2014, Springer Science + Business Media

    Oliver Wirths

  71. Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing

    Article • Frontiers in Aging Neuroscience, April 2014, Frontiers

    Oliver Wirths

  72. Aβ38 in the Brains of Patients with Sporadic and Familial Alzheimer's Disease and Transgenic Mouse Models

    Article • Journal of Alzheimer’s Disease, February 2014, IOS Press

    Oliver Wirths

  73. Immunolesion-induced loss of cholinergic projection neurones promotes β-amyloidosis and tau hyperphosphorylation in the hippocampus of triple-transgenic mice

    Article • Neuropathology and Applied Neurobiology, January 2014, Wiley

    Oliver Wirths

  74. Abundance of Aβ5-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer’s disease

    Article • Molecular Neurodegeneration, January 2014, Springer Science + Business Media

    Oliver Wirths

  75. Accelerated tau pathology with synaptic and neuronal loss in a novel triple transgenic mouse model of Alzheimer's disease

    Article • Neurobiology of Aging, November 2013, Elsevier

    Oliver Wirths

  76. Oligomeric Pyroglutamate Amyloid-β is Present in Microglia and a Subfraction of Vessels in Patients with Alzheimer's Disease: Implications for Immunotherapy

    Article • Journal of Alzheimer’s Disease, May 2013, IOS Press

    Oliver Wirths

  77. N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits

    Article • Acta Neuropathologica, May 2013, Springer Science + Business Media

    Oliver Wirths

  78. Abundant pyroglutamate-modified ABri and ADan peptides in extracellular and vascular amyloid deposits in familial British and Danish dementias

    Article • Neurobiology of Aging, May 2013, Elsevier

    Oliver Wirths

  79. Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer’s disease

    Article • Acta Neuropathologica, March 2013, Springer Science + Business Media

    Oliver Wirths

  80. N-truncated Abeta starting with position four: early intraneuronal accumulation and rescue of toxicity using NT4X-167, a novel monoclonal antibody

    Article • Acta Neuropathologica Communications, January 2013, Springer Science + Business Media

    Oliver Wirths

  81. Problems During Aging (Alzheimer’s and Others)

    Article • January 2013, Springer Science + Business Media

    Oliver Wirths

  82. The Arctic AβPP mutation leads to Alzheimer’s disease pathology with highly variable topographic deposition of differentially truncated Aβ

    Article • Acta Neuropathologica Communications, January 2013, Springer Science + Business Media

    Oliver Wirths

  83. Intraneuronal Aβ accumulation and neurodegeneration: Lessons from transgenic models

    Article • Life Sciences, December 2012, Elsevier

    Oliver Wirths

  84. Amyloid Precursor Protein Is a Biomarker for Transformed Human Pluripotent Stem Cells

    Article • American Journal Of Pathology, April 2012, Elsevier

    Oliver Wirths

  85. No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease

    Article • Neurobiology of Aging, April 2012, Elsevier

    Oliver Wirths

  86. Antibody 9D5 Recognizes Oligomeric Pyroglutamate Amyloid-β in a Fraction of Amyloid-β Deposits in Alzheimer's Disease without Cross-Reactivity with other Protein Aggregates

    Article • Journal of Alzheimer’s Disease, March 2012, IOS Press

    Prof. Herbert Budka, Oliver Wirths

  87. AβPP Accumulation and/or Intraneuronal Amyloid-β Accumulation? The 3xTg-AD Mouse Model Revisited

    Article • Journal of Alzheimer’s Disease, February 2012, IOS Press

    Oliver Wirths

  88. Pyroglutamate Amyloid β (Aβ) Aggravates Behavioral Deficits in Transgenic Amyloid Mouse Model for Alzheimer Disease

    Article • Journal of Biological Chemistry, January 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Oliver Wirths

  89. Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice

    Article • Neurobiology of Aging, January 2012, Elsevier

    Oliver Wirths

  90. Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease

    Article • Neurobiology of Aging, January 2012, Elsevier

    Oliver Wirths

  91. Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease

    Article • Journal of Biological Chemistry, September 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Oliver Wirths

  92. Reduced levels of IgM autoantibodies against N-truncated pyroglutamate Aβ in plasma of patients with Alzheimer's disease

    Article • Neurobiology of Aging, August 2011, Elsevier

    Oliver Wirths

  93. Intraneuronal Aβ as a trigger for neuron loss: can this be translated into human pathology?

    Article • Biochemical Society Transactions, July 2011, Portland Press Ltd.

    Oliver Wirths

  94. Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Phenotype in 5XFAD Mice

    Article • Journal of Biological Chemistry, December 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Oliver Wirths

  95. Identification of Low Molecular Weight Pyroglutamate Aβ Oligomers in Alzheimer Disease

    Article • Journal of Biological Chemistry, October 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Oliver Wirths

  96. Concomitant detection of β-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice

    Article • Journal of Chemical Neuroanatomy, September 2010, Elsevier

    Oliver Wirths

  97. Intracellular Aβ triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease

    Article • Neurobiology of Aging, July 2010, Elsevier

    Oliver Wirths

  98. Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease

    Article • Neurobiology of Aging, May 2010, Elsevier

    Oliver Wirths

  99. Accumulation of intraneuronal Aβ correlates with ApoE4 genotype

    Article • Acta Neuropathologica, March 2010, Springer Science + Business Media

    Oliver Wirths

  100. Gene expression of neuregulin-1 isoforms in different brain regions of elderly schizophrenia patients

    Article • The World Journal of Biological Psychiatry, March 2010, Taylor & Francis

    Oliver Wirths

  101. Histone Deacetylase Inhibitor Valproic Acid Inhibits Cancer Cell Proliferation via Down-regulation of the Alzheimer Amyloid Precursor Protein

    Article • Journal of Biological Chemistry, February 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Oliver Wirths

  102. Intracellular accumulation of amyloid-beta – a predictor for synaptic dysfunction and neuron loss in Alzheimer’s disease

    Article • Frontiers in Aging Neuroscience, January 2010, Frontiers

    Oliver Wirths

  103. Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

    Article • International Journal of Alzheimer s Disease, January 2010, Hindawi Publishing Corporation

    Oliver Wirths

  104. Formic acid is essential for immunohistochemical detection of aggregated intraneuronal Aβ peptides in mouse models of Alzheimer's disease

    Article • Brain Research, November 2009, Elsevier

    Oliver Wirths

  105. Pyroglutamate Abeta pathology in APP/PS1KI mice, sporadic and familial Alzheimer’s disease cases

    Article • Acta Neurovegetativa, October 2009, Springer Science + Business Media

    Oliver Wirths

  106. Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

    Article • Acta Neuropathologica, June 2009, Springer Science + Business Media

    Oliver Wirths

  107. Circulating immune complexes of Aβ and IgM in plasma of patients with Alzheimer’s disease

    Article • Acta Neurovegetativa, May 2009, Springer Science + Business Media

    Oliver Wirths

  108. APP/PS1KI bigenic mice develop early synaptic deficits and hippocampus atrophy

    Article • Acta Neuropathologica, April 2009, Springer Science + Business Media

    Oliver Wirths

  109. Die modifizierte Amyloid-Hypothese der Alzheimer-Demenz – intraneuronales Abeta induziert Neurodegeneration

    Article • e-Neuroforum, January 2009, De Gruyter

    Oliver Wirths

  110. Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice

    Article • Acta Neuropathologica, October 2008, Springer Science + Business Media

    Oliver Wirths

  111. Effect of copper intake on CSF parameters in patients with mild Alzheimer’s disease: a pilot phase 2 clinical trial

    Article • Acta Neurovegetativa, October 2008, Springer Science + Business Media

    Oliver Wirths

  112. Early Intraneuronal β-Amyloid Pathology: Do Transgenic Mice Represent Valid Model Systems?

    Article • Open Longevity Science, October 2008, Bentham Science Publishers

    Oliver Wirths

  113. Alzheimer-Demenz

    Article • Der Nervenarzt, September 2008, Springer Science + Business Media

    Oliver Wirths

  114. Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice

    Article • Brain Research, July 2008, Elsevier

    Oliver Wirths

  115. Deficits in working memory and motor performance in the APP/PS1ki mouse model for Alzheimer's disease

    Article • Neurobiology of Aging, June 2008, Elsevier

    Oliver Wirths

  116. Motor impairment in Alzheimer’s disease and transgenic Alzheimer’s disease mouse models

    Article • Genes Brain & Behavior, January 2008, Wiley

    Oliver Wirths

  117. Review on the APP/PS1KI mouse model: intraneuronal Aβ accumulation triggers axonopathy, neuron loss and working memory impairment

    Article • Genes Brain & Behavior, January 2008, Wiley

    Oliver Wirths

  118. Intraneuronal β-Amyloid Is a Major Risk Factor – Novel Evidence from the APP/PS1KI Mouse Model

    Article • Neurodegenerative Diseases, January 2008, Karger Publishers

    Oliver Wirths

  119. Age-dependent axonal degeneration in an Alzheimer mouse model

    Article • Neurobiology of Aging, November 2007, Elsevier

    Oliver Wirths

  120. Altered cholesterol metabolism in APP695-transfected neuroblastoma cells

    Article • Brain Research, June 2007, Elsevier

    Oliver Wirths

  121. Gender dependent APP processing in a transgenic mouse model of Alzheimer’s disease

    Article • Acta Neurovegetativa, October 2006, Springer Science + Business Media

    Oliver Wirths

  122. Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease

    Article • Acta Neuropathologica, March 2006, Springer Science + Business Media

    Oliver Wirths

  123. Decreased plasma cholesterol levels during aging in transgenic mouse models of Alzheimer's disease

    Article • Experimental Gerontology, February 2006, Elsevier

    Oliver Wirths

  124. OTX1 and OTX2 Expression Correlates With the Clinicopathologic Classification of Medulloblastomas

    Article • Journal of Neuropathology & Experimental Neurology, February 2006, Oxford University Press (OUP)

    Oliver Wirths

  125. Traumatic brain injury: cause or risk of Alzheimer’s disease? A review of experimental studies

    Article • Acta Neurovegetativa, June 2005, Springer Science + Business Media

    Oliver Wirths

  126. A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide - the first step of a fatal cascade

    Article • Journal of Neurochemistry, November 2004, Wiley

    Oliver Wirths

  127. Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice

    Article • Experimental Neurology, November 2003, Elsevier

    Oliver Wirths

  128. No alterations of hippocampal neuronal number and synaptic bouton number in a transgenic mouse model expressing the β-cleaved C-terminal APP fragment

    Article • Neurobiology of Disease, March 2003, Elsevier

    Oliver Wirths

  129. α-Synuclein, Aβ and Alzheimer's disease

    Article • Progress in Neuro-Psychopharmacology and Biological Psychiatry, February 2003, Elsevier

    Oliver Wirths

  130. Reelin in plaques of β-amyloid precursor protein and presenilin-1 double-transgenic mice

    Article • Neuroscience Letters, December 2001, Elsevier

    Oliver Wirths

  131. Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

    Article • Neuroscience Letters, June 2001, Elsevier

    Oliver Wirths