All Stories

  1. Vascular dysfunctions during radiation retinopathy

    Article • Radiotherapy and Oncology, November 2025, Elsevier

    PhD François E Paris

  2. Metabolic profiling of glioblastoma stem cells reveals pyruvate carboxylase as a critical survival factor and potential therapeutic target

    Article • Neuro-Oncology, June 2024, Oxford University Press (OUP)

    PhD François E Paris

  3. Exploiting radiation immunostimulatory effects to improve glioblastoma outcome

    Article • Neuro-Oncology, October 2022, Oxford University Press (OUP)

    PhD François E Paris

  4. Microvalve bioprinting as a biofabrication tool to decipher tumor and endothelial cell crosstalk: Application to a simplified glioblastoma model

    Article • Bioprinting, December 2021, Elsevier

    PhD François E Paris

  5. Wild-type isocitrate dehydrogenase under the spotlight in glioblastoma

    Article • Oncogene, November 2021, Springer Science + Business Media

    PhD François E Paris

  6. Towards a Reduced In Silico Model Predicting Biochemical Recurrence After Radiotherapy in Prostate Cancer

    Article • IEEE Transactions on Biomedical Engineering, September 2021, Institute of Electrical & Electronics Engineers (IEEE)

    PhD François E Paris

  7. SIRPα-specific monoclonal antibody enables antibody-dependent phagocytosis of neuroblastoma cells

    Article • Medical Oncology, May 2021, Springer Science + Business Media

    PhD François E Paris

  8. Altered Macrophage Function Associated with Crystalline Lung Inflammation in Acid Sphingomyelinase Deficiency

    Article • American Journal of Respiratory Cell and Molecular Biology, May 2021, American Thoracic Society

    PhD François E Paris

  9. Mechanistic Simulation of Tumor Response Outperforms Radiomics Predicting Recurrence in Prostate Cancer Radiotherapy

    Article • April 2021, Institute of Electrical & Electronics Engineers (IEEE)

    PhD François E Paris

  10. 53BP1 Repair Kinetics for Prediction of In Vivo Radiation Susceptibility in 15 Mouse Strains

    Article • Radiation Research, September 2020, Radiation Research Society

    PhD François E Paris

  11. Glutamine uptake and utilization of human mesenchymal glioblastoma in orthotopic mouse model

    Article • Cancer & Metabolism, August 2020, Springer Science + Business Media

    PhD François E Paris

  12. Sphingolipid distribution at mitochondria-associated membranes (MAMs) upon induction of apoptosis

    Article • Journal of Lipid Research, July 2020, Elsevier

    PhD François E Paris

  13. Secretion of Acid Sphingomyelinase and Ceramide by Endothelial Cells Contributes to Radiation-Induced Intestinal Toxicity

    Article • Cancer Research, June 2020, American Association for Cancer Research (AACR)

    PhD François E Paris

  14. Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor–stroma interactions

    Article • Cell Death and Disease, April 2020, Springer Science + Business Media

    PhD François E Paris

  15. Exercise training improves radiotherapy efficiency in a murine model of prostate cancer

    Article • The FASEB Journal, February 2020, Wiley

    PhD François E Paris

  16. Influence of Radiotherapy Fractionation Schedule on the Tumor Vascular Microenvironment in Prostate and Lung Cancer Models

    Article • Cancers, January 2020, MDPI AG

    PhD François E Paris

  17. Establishing mechanisms affecting the individual response to ionising radiation

    Article • International Journal of Radiation Biology, December 2019, Taylor & Francis

    PhD François E Paris

  18. Tumor vasculature remodeling by radiation therapy increases doxorubicin distribution and efficacy

    Article • Cancer Letters, August 2019, Elsevier

    PhD François E Paris

  19. Impairing temozolomide resistance driven by glioma stem‐like cells with adjuvant immunotherapy targeting O‐acetyl GD2 ganglioside

    Article • International Journal of Cancer, July 2019, Wiley

    PhD François E Paris

  20. Reoxygenation during radiotherapy in intermediate-risk prostate cancer

    Article • Radiotherapy and Oncology, April 2019, Elsevier

    PhD François E Paris

  21. PO-0969 Sensitivity analysis of an in silico model of prostate tumour growth and response to radiotherapy

    Article • Radiotherapy and Oncology, April 2019, Elsevier

    PhD François E Paris

  22. Sensitivity Analysis Of An In Silico Model Of Tumor Growth And Radiation Response

    Article • April 2019, Institute of Electrical & Electronics Engineers (IEEE)

    PhD François E Paris

  23. Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target

    Article • Frontiers in Oncology, March 2019, Frontiers

    PhD François E Paris

  24. EP-1998: In silico modelling of the impact of the fractionation for hypofractionated prostate treatments

    Article • Radiotherapy and Oncology, April 2018, Elsevier

    PhD François E Paris

  25. A new tissue segmentation method to calculate 3D dose in small animal radiation therapy

    Article • Radiation Oncology, February 2018, Springer Science + Business Media

    PhD François E Paris

  26. Evaluation of tumor hypoxia prior to radiotherapy in intermediate-risk prostate cancer using 18F-fluoromisonidazole PET/CT: a pilot study

    Article • Oncotarget, January 2018, Impact Journals, LLC

    PhD François E Paris

  27. Neuroblastoma chemotherapy can be augmented by immunotargeting O-acetyl-GD2 tumor-associated ganglioside

    Article • OncoImmunology, September 2017, Taylor & Francis

    PhD François E Paris

  28. Ionizing radiation induces long-term senescence in endothelial cells through mitochondrial respiratory complex II dysfunction and superoxide generation

    Article • Free Radical Biology and Medicine, July 2017, Elsevier

    PhD François E Paris

  29. The p38 pathway, a major pleiotropic cascade that transduces stress and metastatic signals in endothelial cells

    Article • Oncotarget, May 2017, Impact Journals, LLC

    PhD François E Paris

  30. Optimizing radiotherapy protocols using computer automata to model tumour cell death as a function of oxygen diffusion processes

    Article • Scientific Reports, May 2017, Springer Science + Business Media

    PhD François E Paris

  31. Plasma membrane reorganization links acid sphingomyelinase/ceramide to p38 MAPK pathways in endothelial cells apoptosis

    Article • Cellular Signalling, May 2017, Elsevier

    PhD François E Paris

  32. TargetingO-Acetyl-GD2 Ganglioside for Cancer Immunotherapy

    Article • Journal of Immunology Research, January 2017, Hindawi Publishing Corporation

    PhD François E Paris

  33. Rapid Diminution in the Level and Activity of DNA-Dependent Protein Kinase in Cancer Cells by a Reactive Nitro-Benzoxadiazole Compound

    Article • International Journal of Molecular Sciences, May 2016, MDPI AG

    Professor Vehary Sakanyan, PhD François E Paris

  34. Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside

    Article • Oncotarget, May 2016, Impact Journals, LLC

    PhD François E Paris

  35. Oxidative stress disassembles the p38/NPM/PP2A complex, which leads to modulation of nucleophosmin-mediated signaling to DNA damage response

    Article • The FASEB Journal, May 2016, Federation of American Societies For Experimental Biology (FASEB)

    PhD François E Paris, Hala Estéphan, soizic dutoit

  36. Plasma ceramide, a real-time predictive marker of pulmonary and hepatic metastases response to stereotactic body radiation therapy combined with irinotecan

    Article • Radiotherapy and Oncology, May 2016, Elsevier

    PhD François E Paris

  37. Krüppel-like factor 4: A new potential biomarker of lung cancer

    Article • Molecular and Clinical Oncology, April 2016, Spandidos Publications

    Associate Professor Marie Claude J Fadous khalife , PhD François E Paris

  38. Validation of fast Monte Carlo dose calculation in small animal radiotherapy with EBT3 radiochromic films

    Article • Physics in Medicine and Biology, April 2016, Institute of Physics Publishing

    PhD François E Paris, David Sarrut

  39. Radiothérapie hypofractionnée : quelles sont les règles à suivre ?

    Article • Cancer/Radiothérapie, October 2015, Elsevier

    PhD François E Paris

  40. Radiation-induced PGE2 sustains human glioma cells growth and survival through EGF signaling

    Article • Oncotarget, February 2015, Impact Journals, LLC

    PhD François E Paris

  41. Bioactive lipids and the control of Bax pro-apoptotic activity

    Article • Cell Death and Disease, May 2014, Springer Science + Business Media

    PhD François E Paris

  42. Chimeric Antibody c.8B6 to O-Acetyl-GD2 Mediates the Same Efficient Anti-Neuroblastoma Effects as Therapeutic ch14.18 Antibody to GD2 without Antibody Induced Allodynia

    Article • PLOS One, February 2014, PLOS

    PhD François E Paris

  43. Underestimation of dose delivery in preclinical irradiation due to scattering conditions

    Article • Physica Medica, February 2014, Elsevier

    PhD François E Paris

  44. Improved Functionality of the Vasculature during Conventionally Fractionated Radiation Therapy of Prostate Cancer

    Article • PLOS One, December 2013, PLOS

    PhD François E Paris

  45. Membrane Signaling Induced by High Doses of Ionizing Radiation in the Endothelial Compartment. Relevance in Radiation Toxicity

    Article • International Journal of Molecular Sciences, November 2013, MDPI AG

    PhD François E Paris

  46. Cell cycle arrest and apoptosis induced by O-acetyl-GD2-specific monoclonal antibody 8B6 inhibits tumor growth in vitro and in vivo

    Article • Cancer Letters, June 2013, Elsevier

    PhD François E Paris

  47. Corrigendum to “Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions” [Radiother Oncol 106 (2013) 138–146]

    Article • Radiotherapy and Oncology, May 2013, Elsevier

    PhD François E Paris

  48. Inhibition of tumor angiogenesis by globotriaosylceramide immunotargeting

    Article • OncoImmunology, April 2013, Taylor & Francis

    PhD François E Paris

  49. Re-orienting the immune system

    Article • OncoImmunology, April 2013, Taylor & Francis

    PhD François E Paris

  50. Differentiation-Related Response to DNA Breaks in Human Mesenchymal Stem Cells

    Article • Stem Cells, March 2013, Wiley

    PhD François E Paris

  51. Radiosensitization of prostate cancer cells by the dual PI3K/mTOR inhibitor BEZ235 under normoxic and hypoxic conditions

    Article • Radiotherapy and Oncology, January 2013, Elsevier

    PhD François E Paris

  52. Anti-Gb3 Monoclonal Antibody Inhibits Angiogenesis and Tumor Development

    Article • PLOS One, November 2012, PLOS

    PhD François E Paris

  53. Toxicité rectale de la radiothérapie : signes cliniques, physiopathologie et prise en charge

    Article • Cancer/Radiothérapie, September 2012, Elsevier

    PhD François E Paris

  54. Radiobiologie appliquée à l’endothélium

    Article • Cancer/Radiothérapie, February 2012, Elsevier

    PhD François E Paris

  55. Stereotactic body radiation therapy for abdominal oligometastases: a biological and clinical review

    Article • Radiation Oncology, January 2012, Springer Science + Business Media

    PhD François E Paris

  56. RhoA GTPase regulates radiation-induced alterations in endothelial cell adhesion and migration

    Article • Biochemical and Biophysical Research Communications, November 2011, Elsevier

    PhD François E Paris

  57. A Monoclonal Antibody to O-Acetyl-GD2 Ganglioside and Not to GD2 Shows Potent Anti-Tumor Activity without Peripheral Nervous System Cross-Reactivity

    Article • PLOS One, September 2011, PLOS

    PhD François E Paris

  58. Current state of knowledge regarding the use of antiangiogenic agents with radiation therapy

    Article • Cancer Treatment Reviews, May 2011, Elsevier

    PhD François E Paris

  59. S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism

    Article • Cell Death and Disease, February 2011, Springer Science + Business Media

    PhD François E Paris

  60. Sphingosine-1-Phosphate Activates the AKT Pathway to Protect Small Intestines from Radiation-Induced Endothelial Apoptosis

    Article • Cancer Research, November 2010, American Association for Cancer Research (AACR)

    PhD François E Paris

  61. « Dose-painting » : mythe ou réalité ?

    Article • Cancer/Radiothérapie, October 2010, Elsevier

    PhD François E Paris

  62. Plasma membrane signaling induced by ionizing radiation

    Article • Mutation Research/Reviews in Mutation Research, April 2010, Elsevier

    PhD François E Paris

  63. Comparative Toxicity and Efficacy of Combined Radioimmunotherapy and Antiangiogenic Therapy in Carcinoembryonic Antigen-Expressing Medullary Thyroid Cancer Xenograft

    Article • Journal of Nuclear Medicine, March 2010, Society of Nuclear Medicine

    PhD François E Paris

  64. Deficiency or blockade of angiotensin II type 2 receptor delays tumorigenesis by inhibiting malignant cell proliferation and angiogenesis

    Article • International Journal of Cancer, February 2010, Wiley

    PhD François E Paris

  65. Toxicity and efficacy of combined radioimmunotherapy and bevacizumab in a mouse model of medullary thyroid carcinoma

    Article • Cancer, February 2010, Wiley

    PhD François E Paris

  66. Review and meta-analysis of epidemiological associations between low/moderate doses of ionizing radiation and circulatory disease risks, and their possible mechanisms

    Article • Radiation and Environmental Biophysics, October 2009, Springer Science + Business Media

    Dr Soile Tapio, PhD François E Paris

  67. Relationship between responsiveness of cancer cells to Oncostatin M and/or IL‐6 and survival of stage III melanoma patients treated with tumour‐infiltrating lymphocytes

    Article • The Journal of Pathology, September 2008, Wiley

    PhD François E Paris

  68. A Systematic Review of Epidemiological Associations between Low and Moderate Doses of Ionizing Radiation and Late Cardiovascular Effects, and Their Possible Mechanisms

    Article • Radiation Research, January 2008, Radiation Research Society

    Dr Soile Tapio, PhD François E Paris

  69. Binding Activities and Antitumor Properties of a New Mouse/Human Chimeric Antibody Specific for GD2 Ganglioside Antigen

    Article • Clinical Cancer Research, September 2007, American Association for Cancer Research (AACR)

    PhD François E Paris

  70. Radiothérapie interne vectorisée : seule ou en association ?

    Article • Médecine Nucléaire, September 2007, Elsevier

    PhD François E Paris

  71. Sphingosine-1-Phosphate Protects Proliferating Endothelial Cells from Ceramide-Induced Apoptosis but not from DNA Damage-Induced Mitotic Death

    Article • Cancer Research, February 2007, American Association for Cancer Research (AACR)

    PhD François E Paris

  72. Intestinal Epithelial Cell Dysfunction is Mediated by an Endothelial-Specific Radiation-Induced Bystander Effect

    Article • Radiation Research, February 2007, Radiation Research Society

    PhD François E Paris

  73. Enteric glia inhibit intestinal epithelial cell proliferation partly through a TGF-β1-dependent pathway

    Article • AJP Gastrointestinal and Liver Physiology, January 2007, American Physiological Society

    PhD François E Paris

  74. Multiple Trichoepitheliomas in the Lines of Blaschko

    Article • Pediatric Dermatology, March 2006, Wiley

    PhD François E Paris

  75. Erratum: Corrigendum: ATM regulates target switching to escalating doses of radiation in the intestines

    Article • Nature Medicine, February 2006, Springer Science + Business Media

    PhD François E Paris

  76. ATM regulates target switching to escalating doses of radiation in the intestines

    Article • Nature Medicine, May 2005, Springer Science + Business Media

    PhD François E Paris

  77. Tumor Response to Radiotherapy Regulated by Endothelial Cell Apoptosis

    Article • Science, May 2003, American Association for the Advancement of Science

    PhD François E Paris

  78. Erratum: Streptococcus pyogenes and phagocytic killing

    Article • Nature Medicine, November 2002, Springer Science + Business Media

    PhD François E Paris

  79. Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring

    Article • Nature Medicine, September 2002, Springer Science + Business Media

    PhD François E Paris

  80. Insertional Mutagenesis of the Mouse Acid Ceramidase Gene Leads to Early Embryonic Lethality in Homozygotes and Progressive Lipid Storage Disease in Heterozygotes

    Article • Genomics, June 2002, Elsevier

    PhD François E Paris

  81. Correlation between antioxidant status, tumorigenicity and radiosensitivity in sister rat cell lines

    Article • Carcinogenesis, May 2002, Oxford University Press (OUP)

    PhD François E Paris

  82. Insertional Mutagenesis of the Mouse Acid Ceramidase Gene Leads to Early Embryonic Lethality in Homozygotes and Progressive Lipid Storage Disease in Heterozygotes

    Article • Genomics, February 2002, Elsevier

    PhD François E Paris

  83. Endothelial Apoptosis as the Primary Lesion Initiating Intestinal Radiation Damage in Mice

    Article • Science, July 2001, American Association for the Advancement of Science

    PhD François E Paris

  84. Ceramide Enables Fas to Cap and Kill

    Article • Journal of Biological Chemistry, April 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD François E Paris

  85. Comment bloquer l'apoptose des ovocytes.

    Article • médecine/sciences, January 2001, INIST-CNRS

    PhD François E Paris

  86. Natural Ceramide Reverses Fas Resistance ofAcid Sphingomyelinase−/−Hepatocytes

    Article • Journal of Biological Chemistry, November 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD François E Paris

  87. Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine -1-phosphate therapy

    Article • Nature Medicine, October 2000, Springer Science + Business Media

    PhD François E Paris

  88. CD95-mediated apoptosis in vivo requires acid sphingomyelinase

    Article • Journal of Biological Chemistry, June 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD François E Paris

  89. Role of Acidic Sphingomyelinase in Fas/CD95-mediated Cell Death

    Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD François E Paris

  90. Enhanced Expression of the Kin17 Protein Immediately after Low Doses of Ionizing Radiation

    Article • Radiation Research, April 1997, JSTOR

    PhD François E Paris