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Energetic deterioration in white matter in Alzheimer's disease is specific to glucose and occurs first in limbic tracts. Ketone supply, the brain’s alternative fuel to glucose, is either unchanged or higher in white matter tracts in Alzheimer's disease.

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This page is a summary of: Fascicle- and Glucose-Specific Deterioration in White Matter Energy Supply in Alzheimer’s Disease, Journal of Alzheimer s Disease, June 2020, IOS Press,
DOI: 10.3233/jad-200213.
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