What is it about?

We completed a Systematic Review to evaluate whether Immersive Virtual Reality (iVR) is acceptable and useful in the Assessment and Treatment of Alzheimer's Disease

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Why is it important?

Alzheimer's Disease is the most common form of dementia in the world and affects of many millions of patients and their families. We do not have any effective treatment to modify the progression of disease. Focus is now on identifying Alzheimer's disease as early as possible to try and modify outcomes and providing support to those already affected. iVR allows an individual to enter a computer generated world which they control intuitively. Depending on the goal this environment can be configured to challenge or support their spatial navigation and cognition. As we know spatial navigation is affected early in Alzheimer's Disease the technology can be used to formally assess potential deficits. The relative efficacy of iVR for assessment and and the value of iVR in the treatment of Alzheimer's Disease is not well defined. Other reviews have looked at this area more broadly but none specifically at immersive technology which has the most powerful potential to engage patients intuitively and support their early deficits in spatial navigation affected as part of their disease process. We found that iVR is emerging as a viable method of assessing older adults and people with AD. Strongest benefits were seen when closely integrated with theoretical models of neurodegeneration and existing screening methods. Further randomized controlled trials integrated with clinical populations are required. This will consolidate the power of iVR for assessment of MCI and clarify treatment efficacy beyond current applications in physical rehabilitation.

Perspectives

Excitingly we already have evidence that iVR can detect preclinical deficits in spatial navigation which correlate with patients at high genetic risk of subsequent dementia. Development of this this research is hoped to allow low cost, intuitive assessment which can contribute to early treatment. I am also very interested in the potential of iVR for bringing people together, reducing inequality around functional deficits and reducing distress. In our review we see that people with Alzheimer's Dementia mostly enjoy iVR technology which can support their deficits in spatial navigation and functional limitations. At the time of publication the world has changed significantly due to social distancing measures which are especially onerous for those with cognitive deficits and I hope iVR can be part of our future support for this group.

Felix Clay
Cambridge and Peterborough Foundation Trust

Read the Original

This page is a summary of: Use of Immersive Virtual Reality in the Assessment and Treatment of Alzheimer’s Disease: A Systematic Review, Journal of Alzheimer s Disease, May 2020, IOS Press,
DOI: 10.3233/jad-191218.
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