Loading... Assessing MBI with the MBI-C in People with MCI

What is it about?

Neuropsychiatric Symptoms (NPS) are non-cognitive, behavioral or psychiatric symptoms that include disturbances of mood, perception, and behavior related to a neurocognitive disorder. NPS are frequent in Mild Cognitive Impairment (MCI) and associated to a higher risk of dementia. The Mild Behavioral Impairment (MBI) is a new diagnostic entity, developed by the International Society to Advance Alzheimer and Treatment (ISTAAART), a subgroup of Alzheimer Association (AA). Subsequently, the Mild Behavioral Impairment-Checklist (MBI-C) was developed by this workgroup to operationalize the measurement of the MBI. Our findings suggest that the MBI-C is useful for sensibly detecting MBI in people with MCI (cutoff point 6.5; sensitivity 1.0, specificity 78.2). We also report a MBI prevalence of 14.2% in our MCI participants. People with MCI presented few and subtle NPS, as measured by the MBI-C. The MBI-C total score correlated with functional, emotional and subjective cognitive measures.

Featured Image

Why is it important?

Our results could be highly beneficial for both clinicians and researchers, by providing a better understanding of the behavioral, cognitive and functional manifestations of neurocognitive diseases.