What is it about?

The aim of the study was to investigate the prognostic value of circulating Bcl-2 and anti-p53 antibodies (p53Abs) in a 17.5-year follow-up of breast cancer patients.

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Why is it important?

Our results suggest that breast cancer patients with high serum levels of p53Abs and Bcl-2 present an especially unfavorable group in a long follow-up.

Perspectives

Analysis of these circulating, apoptosis related markers, may be useful in defining the group of patients that may benefit of some therapeutic modalities.

Maja Sirotkovic-Skerlev
School of Medicine, University of Zagreb, Croatia

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This page is a summary of: Prognostic value of circulating Bcl-2 and anti-p53 antibodies in patients with breast cancer: A long term follow-up (17.5 years), Cancer Biomarkers, February 2021, IOS Press,
DOI: 10.3233/cbm-201497.
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