What is it about?
Irisin improved endothelial function by modulating HO-1/adiponectin axis in perivascular adipose tissue in obese mice.
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Why is it important?
These findings suggest that regulating perivascular adipose tissue function may be a potential mechanism by which irisin improves endothelial function in obesity.
Perspectives
Writing this article was a great pleasure as it has co-authors with whom I have had long standing collaborations. This article also lead to consideration of the importance of perivascular adipose tissue.
Xiaodong Sun
Read the Original
This page is a summary of: Irisin Regulates Heme Oxygenase-1/Adiponectin Axis in Perivascular Adipose Tissue and Improves Endothelial Dysfunction in Diet-Induced Obese Mice, Cellular Physiology and Biochemistry, January 2017, Karger Publishers,
DOI: 10.1159/000477864.
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