Neurology explores the brain and nervous system, with migraine representing a complex and often debilitating condition that affects how the brain processes pain and sensory signals. While migraine is sometimes dismissed as “just a headache,” it can involve a wide range of symptoms including severe throbbing pain, nausea, and sensitivity to light and sound, with significant impacts on daily life. Here we bring together notable scientific stories from across Kudos examining migraine mechanisms, triggers, treatment approaches, and advances in clinical care.