What is it about?
Drug resistant microorganisms are evading conventional drugs at a horrifying rate causing difficulties with treatment of infectious diseases. In view of this, we investigated a microorganism that can produce antibiotics and found it can kill some of the disease causing bugs. We worked further with the microorganisms and discovered it to produce 13 important compounds. All the compounds have useful biological activities, however, 4 among will require further investigation. We concluded that the organism found locally could serve as a valuable source for lead compounds for pharmaceutical purposes.
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Why is it important?
The discovery will assist with more investigations into discovering more lead compounds to fortify or replacing the weak drugs currently in use.
Perspectives
It was a great pleasure collaborating with senior researchers in this field and understanding the nitty grity in the discovery of lead compounds to solve problems of antimicrobial resistance.
Dr Olasinbo Balogun
Institute of Human Virology, Nigeria (IHV-N)
Read the Original
This page is a summary of: GC-MS Analysis and Antimicrobial Activity of the Extract and Fractions of Bacillus subtilis subsp. subtilis 168 Isolated from a River Bank in Nigeria, Microbiology Research Journal International, July 2022, Sciencedomain International,
DOI: 10.9734/mrji/2022/v32i230374.
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GC-MS Analysis and Antimicrobial Activity of the Extract and Fractions of Bacillus subtilis subsp. subtilis 168 Isolated from a River Bank in Nigeria
Drug resistant microorganisms are evading conventional drugs at a horrifying rate causing difficulties with treatment of infectious diseases. In view of this, we investigated a microorganism that can produce antibiotics and found it can kill some of the disease causing bugs. We worked further with the microorganisms and discovered it to produce 13 important compounds. All the compounds have useful biological activities, however, 4 among will require further investigation. We concluded that the organism found locally could serve as a valuable source for lead compounds for pharmaceutical purposes.
GC-MS Analysis and Antimicrobial Activity of the Extract and Fractions of Bacillus subtilis subsp. subtilis 168 Isolated from a River Bank in Nigeria
Drug resistant microorganisms are evading conventional drugs at a horrifying rate causing difficulties with treatment of infectious diseases. In view of this, we investigated a microorganism that can produce antibiotics and found it can kill some of the disease causing bugs. We worked further with the microorganisms and discovered it to produce 13 important compounds. All the compounds have useful biological activities, however, 4 among will require further investigation. We concluded that the organism found locally could serve as a valuable source for lead compounds for pharmaceutical purposes.
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