What is it about?
Mice subjected to long term stress showed in the kidney degeneration of the cells of the glomerulus and the convoluted tubules. In the liver, they showed congested sinusoids and the presence of some fatty change, whereas in the suprarenal gland mice subjected to 21 days of stress showed moderate hypertrophy and hyperplasia of the adrenal cortex with the presence of moderate lipoid deposits when compared to controls. The overall effect on short term stress was mild when compared to exposure to 21 days stress
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Why is it important?
Long term stress can cause degeneration in hepatic cells and can also cause nephrotoxicity. In the suprarenal gland, long term stress can induce hypertrophy of the adrenal cortex.
Perspectives
These morphological changes can explain the impaired immunity which develops in organisms that are exposed to chronic stress.
Chukwuma Okafor
Read the Original
This page is a summary of: Effect of Short and Long Term Restraint Stress on the Histology of Liver, Kidney and Suprarenal Gland in Albino Mice during Postweaning Period, Journal of Pharmaceutical Research International, January 2021, Sciencedomain International,
DOI: 10.9734/jpri/2020/v32i4031029.
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