What is it about?
Urinary tract infection (UTI) is one of the most common bacterial infections occurring in both males and females of all ages. Antibiotic resistance in uropathogens is a worldwide problem. Empirical therapy of urinary tract infection (UTI) is based on the susceptibility patterns of locally isolated bacteria in a given time period. Escherichia coli (E.coli), the most common pathogen causing UTI has developed resistance against most of the antibiotics for empirical use.
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Why is it important?
Fosfomycin is one of the best antibiotics to treat UTI, however very little information is available about the susceptibility rate of E. coli to fosfomycin in Nepal
Perspectives
E. coli urinary isolates revealed a high level of resistance to all the antibiotics tested with the exception of fosfomycin. Fosfomycin showed the highest efficacy against E. coli and is the best choice for empirical treatment in Nepal. This study revealed that quinolones, cephalosporins and cotrimoxazole cannot be used for empirical treatment of UTI in Nepal.
Birendra Tiwari
Saint James School of Medicine
Read the Original
This page is a summary of: High Susceptibility of Fosfomycin to Uropathogenic Escherichia coli Isolated at Tertiary Care Hospital of Nepal, Journal of Advances in Microbiology, November 2018, Sciencedomain International,
DOI: 10.9734/jamb/2018/44514.
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