What is it about?
FA is a genetic disorder that has an effect on the nervous system. It affects about 1 in 50,000 people. FA is the most common in Europe, the Middle East, North Africa, South Africa, and quite rare in the Far East. In Native American, Southeast Asians, and Sub-Saharan Africans, this disorder has not been documented. To slow down FA, genetic counseling and gene therapy can be used. Genetic counseling helps people and their families to make informed medical and personal decision. Gene therapy may heal permanently FA disorder. Gene therapy has shown crucial progress in slowing FA disorder in the animal models.
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Why is it important?
This paper described gene therapy for FA disorder. It is important for treatment of FA in future. The paper is very detailed and is easy to understand. It has a figure and three tables.
Perspectives
This is a review paper written beautifully. In this paper, the figure describes the location of FXN gene on the chromosome map. It makes easy for readers to know where the mutated gene location. Table 1 describes gene-shipping vehicles used in gene therapy. Table 2 describes potential gene therapy tools for treating the FA. Table 3 describes gene therapy tools that are useful for the treatment of FA disorder.
Martin Nelwan
Nelwan Institution for Human Resource Development
Read the Original
This page is a summary of: Friedreich Ataxia: Treatment with Genetic Approach, Journal of Advances in Biology & Biotechnology, January 2017, Sciencedomain International,
DOI: 10.9734/jabb/2017/36113.
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