What is it about?

it is about subacute sclerosing panencephalitis (SSPE), which is a progressive degenerative disease caused by measles infection with overall poor prognosis in spite multiple modalities of treatment. Here we report two cases with atypical presentation of early rather than late movement disorder during illness and the unusual association of central precocious puberty preceding the course of illness in one of the cases.

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Why is it important?

it show a different presentation of that disease.

Perspectives

Subacute sclerosing panencephalitis (SSPE) is a progressive degenerative disease caused by measles infection with overall poor prognosis in spite multiple modalities of treatment. The course of the disease is characterized by progressive neurological decline in the form of behavioral and personality changes followed by a stage of characteristic periodic myoclonic spasms followed by a stage of quadriplegia movement disorder, vegetative state and frequently early death. Here we report two cases with atypical presentation of early rather than late movement disorder during illness and the unusual association of central precocious puberty preceding the course of illness in one of the cases.

Hanin Algethami
King Fahad Medical City

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This page is a summary of: Movement Disorder Early in the Presentation of Two Children with Subacute Sclerosing Pan-Encephalitis, International Neuropsychiatric Disease Journal, April 2019, Sciencedomain International,
DOI: 10.9734/indj/2019/v13i130101.
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