What is it about?
This communication describes DNA polymerases, their active site amino acids and a plausible catalytic mechanism
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Why is it important?
This communication analyzes all the DNA polymerases, both from prokayotes and eukaryotes and describes a plausible mechanism of action, based on genetic, site-directed mutagenesis, X-ray crystallographic and protein sequence analysis data using E. coli DNA polymerase-I as the model enzyme
Perspectives
It is a very long paper but interesting to read
Professor Peramachi Palalniveu
Madurai Kamaraj University
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This page is a summary of: DNA Polymerases: An Insight into Their Active Sites and Catalytic Mechanism, International Journal of Biochemistry Research & Review, January 2013, Sciencedomain International,
DOI: 10.9734/ijbcrr/2013/3777.
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