What is it about?

Smokers are more prone to viral and bacterial respiratory infections resulting in acute respiratory failure and have higher mortality rates in the previous outbreak of MERS-CoV 2. Smoking is directly related with the severity of SARS-CoV-2 outcomes among patients, including ICU admission, ventilator use, and higher mortality rates. The higher expression of the angiotensin-converting enzyme-2 (ACE2) receptor, a novel site of SARS-CoV-2 adhesion that causes COVID-19 infection in humans, among smokers further supported this link and placed them in the zone of vulnerability for SARS-CoV-2 infection.

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Why is it important?

It emphasizes on clinically considering the Smoking history among the patients of COVID to minimize the severity of outcomes, and to take immediate clinical precautionary measures and treatment to them to avoid mortality and severity.

Perspectives

I would suggest the scientific community to study and deal cases of COVID-19 by considering this important finding. Awareness should be spread among the general population to quit smoking as well.

Maha Qasim

Read the Original

This page is a summary of: Susceptibility of SARS-CoV-2 COVID-19 Infection among Smokers/Tobacco Users Upregulating the Expression of Angiotensin-Converting Enzyme-2 (ACE2), December 2022, Sciencedomain International,
DOI: 10.9734/bpi/pramr/v2/4385a.
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