What is it about?

Monosodium glutamate is well known flavour enhancer. We have shown the toxic effects (cytotoxicity, free radical generation, and genotoxicity) of MSG on human neuronal cells, which provide information to us this chemical in limited amount. We also used the Celastrus paniculatus seeds extract to mitigate its effect and found potent herbal medicine for neuronal impairment or neurodegenerative diseases. For this we have used IMR-32 human neuronal cells as model.

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Why is it important?

Our findings showed the efficacy of herbal remedy as a neuroprotective agent. As well as it provide information regarding the use of MSG to be controlled as it causes many alteration in human body.

Perspectives

This article is thought-provoking. Especially to the new generation who is having very fast life and eat more fast foods and food packets. This article also support Ayurveda and give primary information for pharmaceutical industry for new formulation in medicinal world for neurodegenerative diseases.

Naumita Shah
Gujarat University

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This page is a summary of: Neuroprotection Effects of Celastrus paniculatus Seed Oil against Monosodium Glutamate in Human IMR-32 Cells, Annual Research & Review in Biology, February 2018, Sciencedomain International,
DOI: 10.9734/arrb/2018/39256.
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