What is it about?
The study aimed to scientifically validate the therapeutic significance of neem in combating multidrug-resistant clinical isolates, including bacteria and fungi. Antimicrobial Assessment and In-silico Molecular Docking of Azadirachta indica (Neem) Leaf Extracts on Some Multidrug Resistance Clinical Isolates" was done. Neem oil had the strongest minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) at 2.00 mg/ml, indicating its potent antimicrobial properties.
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Why is it important?
In-silico molecular docking revealed that bioactive compounds like diethylphthalate and 9,17-octadecadienal (Z) have strong binding affinities with microbial proteins, indicating their potential as microbial inhibitors.
Perspectives
The increasing incidence of antimicrobial resistance has necessitated the development of plant-based alternatives. This study explores the therapeutic properties of the neem plant in combating multidrug-resistant clinical isolates.
Tajudeen Oladunni GANIYU
Fountain University
Read the Original
This page is a summary of: Antimicrobial Assessment and In-silico Molecular Docking of Azadirachta indica (Neem) Leaf Extracts on Some Multidrug Resistance Clinical Isolates, Journal of Advances in Microbiology, October 2025, Sciencedomain International,
DOI: 10.9734/jamb/2025/v25i10999.
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